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RECRUITING Phase 3 ClinicalTrials.gov

A Study Evaluating the Efficacy and Safety of Divarasib and Pembrolizumab Versus Pembrolizumab and Pemetrexed and Carboplatin or Cisplatin in Participants With Previously Untreated, KRAS G12C-Mutated, Advanced or Metastatic Non-Squamous Non-Small Cell Lung Cancer

Sponsor: Hoffmann-La Roche • ClinicalTrials.gov ID: NCT06793215

Registry updated: 2026-10-06
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Description

The purpose of this study is to evaluate the efficacy and safety of divarasib and pembrolizumab compared with pembrolizumab and pemetrexed and carboplatin or cisplatin, for the first-line treatment of adult participants with KRAS G12C-mutated, advanced or metastatic non squamous non-small cell lung cancer (NSCLC).

Interventions

  • Divarasib (Drug)
    Divarasib will be administered orally QD
  • Pembrolizumab (Drug)
    Pembrolizumab will be administered via IV infusion Q3W
  • Pemetrexed (Drug)
    Pemetrexed will be administered via IV infusion Q3W
  • Carboplatin (Drug)
    Carboplatin will be administered via IV infusion Q3W
  • Cisplatin (Drug)
    Cisplatin will be administered via IV infusion Q3W

Eligibility criteria

Inclusion Criteria: * Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1 * Histologically or cytologically confirmed diagnosis of advanced or metastatic non squamous NSCLC that is not eligible for curative surgery and/or definitive chemoradiotherapy * Measurable disease, as defined by RECIST v1.1 * No prior systemic treatment for advanced or metastatic NSCLC * Documentation of the presence of a KRAS G12C mutation * Documentation of known PD-L1 expression status in tumor tissue * Availability of a representative tumor specimen * Adequate end-organ function * Eligible to receive a platinum-based chemotherapy regimen Exclusion Criteria Related to NSCLC: * Known concomitant second oncogenic driver with available targeted treatment * Symptomatic, untreated, or actively progressing central nervous system (CNS) metastases * Spinal cord compression not definitively treated with surgery and/or radiation or previously diagnosed and treated spinal cord compression without evidence that disease has been clinically stable for \>=2 weeks prior to randomization * History of leptomeningeal disease * Uncontrolled tumor-related pain * Uncontrolled pleural effusion, pericardial effusion, or ascites requiring recurrent drainage procedures (once a month or more frequently) Exclusion Criteria Related to Current or Prior Treatments: * Any anti-cancer systemic therapy, including hormonal therapy, within 21 days prior to randomization, or is expected to require any other form of antineoplastic therapy while in the study * Radiation therapy including palliative RT to bone metastases within 2 weeks prior to randomization and RT to the lung \>30Gy within 6 months prior to randomization * Prior treatment with KRAS G12C inhibitors or pan-KRAS/RAS inhibitors * Treatment with systemic immunosuppressive or immunostimulatory medications, including CD137 agonists and immune checkpoint inhibitors * Current treatment with medications that are well known to prolong the QT interval * Treatment with therapeutic oral or IV antibiotics within 2 weeks prior to randomization * Prior allogeneic stem cell or solid organ transplantation Exclusion Criteria Related to General Health: * History of malignancy other than NSCLC within 5 years prior to screening, with the exception of malignancies with a negligible risk of metastasis or death (e.g., 5-year overall survival \[OS\] rate \>90%), such as adequately treated carcinoma in situ of the cervix, non melanoma skin carcinoma, localized prostate cancer, ductal breast carcinoma in situ, or Stage I uterine cancer * Individuals with chronic diarrhea, short bowel syndrome or significant upper gastrointestinal surgery including gastric resection, a history of inflammatory bowel disease (e.g., Crohn's disease or ulcerative colitis) or any active bowel inflammation (including diverticulitis), malabsorption syndrome, conditions that would interfere with enteral absorption * History of idiopathic pulmonary fibrosis, organizing pneumonia (e.g., bronchiolitis obliterans), drug-induced pneumonitis, or idiopathic pneumonitis, or evidence of active pneumonitis on the screening chest computed tomography scan * Significant cardiovascular disease within 3 months prior to screening

Conditions

Non-Small Cell Lung Cancer KRAS G12C Lung Cancer

Locations

  • Alaska Oncology and Hematology — Anchorage, Alaska, United States
  • City of Hope - Phoenix — Goodyear, Arizona, United States
  • Community Cancer Institute (CCI) — Clovis, California, United States
  • Marin Cancer Care Inc — Greenbrae, California, United States
  • UCI Health-CIACC — Irvine, California, United States
  • UCLA Oncology Center — Los Angeles, California, United States
  • Hoag Memorial Hospital — Newport Beach, California, United States
  • University of California Irvine — Orange, California, United States
  • Palo Alto Medical Foundation Research Center — Palo Alto, California, United States
  • Sutter Institute for Medical Research — Roseville, California, United States
  • California Pacific Medical Center — San Francisco, California, United States
  • UC Health Oncology Research — Colorado Springs, Colorado, United States
  • Poudre Valley Health Care, Inc. d/b/a Poudre Valley Health System — Fort Collins, Colorado, United States
  • Hartford Hospital — Hartford, Connecticut, United States
  • Florida Cancer Specialists - SOUTH - SCRI - PPDS — Fort Myers, Florida, United States
  • University of Florida Health at Shands — Gainesville, Florida, United States
  • BioResearch Partner — Hialeah, Florida, United States
  • Memorial Healthcare System - Memorial Regional Hospital — Hollywood, Florida, United States
  • Sylvester Comprehensive Cancer Center — Miami, Florida, United States
  • Advent Health Orlando — Orlando, Florida, United States
  • Ascension Sacred Heart — Pensacola, Florida, United States
  • Florida Cancer Specialists - NORTH - SCRI - PPDS — St. Petersburg, Florida, United States
  • Florida Cancer Specialists - EAST - SCRI - PPDS — West Palm Beach, Florida, United States
  • Piedmont Cancer Institute, PC — Atlanta, Georgia, United States
  • City of Hope® Atlanta — Newnan, Georgia, United States
  • Summit Cancer Care PC — Savannah, Georgia, United States
  • St. Luke's Cancer Institute — Boise, Idaho, United States
  • Affiliated Oncologists, LLC — Chicago Ridge, Illinois, United States
  • Hope and Healing Cancer Services — Hinsdale, Illinois, United States
  • City of Hope® Cancer Center Chicago — Zion, Illinois, United States
  • Mission Cancer + Blood - IMMC — Des Moines, Iowa, United States
  • University of Iowa — Iowa City, Iowa, United States
  • Saint Agnes Hospital - Baltimore - Hunt - PPDS — Baltimore, Maryland, United States
  • Walter Reed National Military Medical Center — Bethesda, Maryland, United States
  • Massachusetts General Hospital — Boston, Massachusetts, United States
  • University of Massachusetts Memorial Medical Center — Worcester, Massachusetts, United States
  • Profound Research, LLC — Farmington Hills, Michigan, United States
  • Metro-Minnesota Community Oncology Research Consortium — Saint Louis Park, Minnesota, United States
  • Missouri Baptist Medical Center — St Louis, Missouri, United States
  • NHO Revive Research Institute — Lincoln, Nebraska, United States
  • Cancer Care Specialists — Reno, Nevada, United States
  • AsteraCancer Care — East Brunswick, New Jersey, United States
  • San Juan Oncology Associates — Farmington, New Mexico, United States
  • SUNY Upstate Medical University — Syracuse, New York, United States
  • Montefiore Einstein Cancer Center — The Bronx, New York, United States
  • Clinical Research Alliance — Westbury, New York, United States
  • Firsthealth of The Carolinas — Pinehurst, North Carolina, United States
  • Ohio State University — Columbus, Ohio, United States
  • Oregon Health and Science University — Portland, Oregon, United States
  • St. Luke's University Health Network — Bethlehem, Pennsylvania, United States
  • Allegheny Cancer Center — Pittsburgh, Pennsylvania, United States
  • Reading Hospital - McGlinn Cancer Institute — West Reading, Pennsylvania, United States
  • Baptist Cancer Center — Memphis, Tennessee, United States
  • The University of Texas Southwestern Medical Center at Dallas — Dallas, Texas, United States
  • Renovatio Clinical - El Paso — El Paso, Texas, United States
  • JPS Health Network — Fort Worth, Texas, United States
  • The University of Texas MD Anderson Cancer Center — Houston, Texas, United States
  • Community Clinical Trials — Kingwood, Texas, United States
  • Texas Tech Health Science Center — Lubbock, Texas, United States
  • Renovatio Clinical — The Woodlands, Texas, United States
  • University of Texas Health Center at Tyler — Tyler, Texas, United States
  • Virginia Oncology Associates — Norfolk, Virginia, United States
  • Ascension Network - St Elizabeth's Hospital — Appleton, Wisconsin, United States
  • Ascension Columbia St. Mary's — Milwaukee, Wisconsin, United States
  • Hospital Aleman de Buenos Aires — Buenos Aires, Argentina
  • Hospital Italiano — Buenos Aires, Argentina
  • Hospital Britanico — Ciudad Autonoma Buenos Aires, Argentina
  • Centro Oncologico Korben — Ciudad Autonoma Buenos Aires, Argentina
  • Clinica Adventista Belgrano — Ciudad Autonoma Buenos Aires, Argentina
  • Kinghorn Cancer Centre — Darlinghurst, New South Wales, Australia
  • Liverpool Hospital — Liverpool, New South Wales, Australia
  • Calvary Mater Newcastle — Waratah, New South Wales, Australia
  • Sunshine Coast University Hospital — Birtinya, Queensland, Australia
  • Royal Hobart Hospital — Hobart, Tasmania, Australia
  • Monash Health — Clayton, Victoria, Australia
  • Austin Health — Heidelberg, Victoria, Australia
  • Peter Maccallum Cancer Centre — Melbourne, Victoria, Australia
  • AZORG Campus Aalst-Moorselbaan — Aalst, Belgium
  • UZ Brussel — Brussels, Belgium
  • Cliniques Universitaires St-Luc — Brussels, Belgium
  • Jessa Zkh (Campus Virga Jesse) — Hasselt, Belgium
  • UZ Leuven Gasthuisberg — Leuven, Belgium
  • CHU de Liège (Sart Tilman) — Liège, Belgium
  • CHU HELORA - Hôpital de Mons - Site Kennedy — Mons, Belgium
  • AZ Delta (Campus Rumbeke) — Roeselare, Belgium
  • Crio - Centro Regional Integrado de Oncologia — Fortaleza, Ceará, Brazil
  • Centro Integrado de Oncologia de Curitiba — Curitiba, Paraná, Brazil
  • Liga Norte Riograndense Contra O Câncer — Natal, Rio Grande do Norte, Brazil
  • Irmandade Da Santa Casa de Misericordia de Porto Alegre — Porto Alegre, Rio Grande do Sul, Brazil
  • Hospital Nossa Senhora da Conceicao — Porto Alegre, Rio Grande do Sul, Brazil
  • Fundação Pio XII Hospital de Câncer de Barretos — Barretos, São Paulo, Brazil
  • Instituto do Cancer do Estado de Sao Paulo - ICESP — São Paulo, São Paulo, Brazil
  • BC Cancer ? Kelowna (Sindi Ahluwalia Hawkins Centre) — Kelowna, British Columbia, Canada
  • BC Cancer - Victoria — Victoria, British Columbia, Canada
  • Royal Victoria Regional Health Centre — Barrie, Ontario, Canada
  • William Osler Health Centre - Brampton Civic Hospital — Brampton, Ontario, Canada
  • Ottawa Hospital Research Institute — Ottawa, Ontario, Canada
  • Jewish General Hospital — Montreal, Quebec, Canada
  • Centre Hospitalier Regional De Rimouski — Rimouski, Quebec, Canada
  • Saskatoon Cancer Centre — Saskatoon, Saskatchewan, Canada
  • CHU de Quebec - Hopital de l'Enfant-Jesus — Québec, Canada
  • Anhui Provincial Hospital(The First Affiliated Hospital of USTC) — Hefei, Anhui, China
  • The First Affiliated Hospital of Nanchang University — Nanchang, Jiangxi, China
  • Beijing Cancer Hospital — Beijing, China
  • Hunan Cancer Hospital — Changsha, China
  • West China Hospital - Sichuan University — Chengdu, China
  • The First Affilicated Hospital, Sun Yat-sen University — Guangzhou, China
  • Sir Run Run Shaw Hospital Zhejiang University — Hangzhou, China
  • Harbin Medical University Cancer Hospital — Harbin, China
  • Shandong Cancer Hospital — Jinan, China
  • Yunnan Cancer Hospital — Kunming, China
  • Nantong Tumor Hospital — Nantong, China
  • Fudan University Shanghai Cancer Center — Shanghai, China
  • Shanghai East Hospital — Shanghai, China
  • Shanghai Pulmonary Hospital — Shanghai, China
  • Tumor Hospital of the affiliated medical college of Shantou University — Shantou, China
  • Hubei Cancer Hospital — Wuhan, China
  • Sjællands Universitetshospital, Køge;Onkologisk Afdeling — Køge, Denmark > Enter Text, Denmark
  • Aarhus Universitetshospital — Aarhus N, Denmark
  • Herlev Hospital, Afdeling for Kræftbehandling, Center for Kræftforskning, Klinisk Forskningsenhed — Herlev, Denmark
  • Rigshospitalet — København Ø, Denmark
  • Onkologisk Ambulatorium - Sønderborg — Sønderborg, Denmark
  • CHU Angers — Angers, France
  • Hopital Avicenne — Bobigny, France
  • Hôpital Louis Pradel, Hospices Civils de Lyon — Bron, France
  • Centre Francois Baclesse — Caen, France
  • Centre Leon Berard — Lyon, France
  • CHU Montpellier — Montpellier, France
  • Centre Antoine Lacassagne — Nice, France
  • Groupe Hospitalier Paris Saint Joseph — Paris, France
  • Hopital Tenon — Paris, France
  • CHU Bordeaux — Pessac, France
  • Centre Hospitalier Universitaire de Reims — Reims, France
  • CH de Saint Quentin — Saint-Quentin, France
  • CHU Strasbourg - Nouvel Hopital Civil — Strasbourg, France
  • Centre Hospitalier Bretagne Atlantique Vannes — Vannes, France
  • Vivantes - Klinikum Im Friedrichshain;Innere Medizin ? Hämatologie, Onkologie und Palliativmedizin — Berlin, Germany
  • Charite - Universitätsmedizin Berlin — Berlin, Germany
  • Helios Klinikum Emil von Behring GmbH — Berlin, Germany
  • Technische Universität Dresden - Medizinische Fakultät Carl Gustav Carus;Medizinische Klinik und Poliklinik I — Dresden, Germany
  • KEM/Evang. Kliniken Essen Mitte gGmbH — Essen, Germany
  • Universitätsklinikum Essen — Essen, Germany
  • Klinikum Esslingen — Esslingen am Neckar, Germany
  • Asklepios Fachkliniken GmbH — Gauting, Germany
  • LungenClinic Grosshansdorf GmbH — Großhansdorf, Germany
  • Christliches Klinikum Halle (Saale) GmbH, Standort Dölau — Halle, Germany
  • Universitätsklinikum Hamburg-Eppendorf — Hamburg, Germany
  • Asklepios Klinik Harburg — Hamburg, Germany
  • KRH Klinikum Siloah-Oststadt-Heidehaus — Hanover, Germany
  • Thoraxklinik Heidelberg gGmbH — Heidelberg, Germany
  • Universität Des Saarlandes — Homburg, Germany
  • Lungenfachklinik Immenhausen — Immenhausen, Germany
  • ViDia Christliche Kliniken Karlsruhe;Medizinische Klinik 2, Studienzentrale Prof. MzB. / Raum G.018 — Karlsruhe, Germany
  • SLK Kliniken Heilbronn GmbH, Standort Fachklinik Löwenstein — Löwenstein, Germany
  • Universitätsklinikum Schleswig-Holstein — Lübeck, Germany
  • Universität Mannheim — Mannheim, Germany
  • Klinikum Bogenhausen — München, Germany
  • Universitaetsklinikum Muenster — Münster, Germany
  • Pius Hospital Oldenburg — Oldenburg, Germany
  • Universitätsklinikum Regensburg — Regensburg, Germany
  • Universitätsklinikum Tübingen — Tübingen, Germany
  • Klinikum Würzburg Mitte gGmbH — Würzburg, Germany
  • Sotiria General Hospital of Athens — Athens, Greece
  • Alexandras Hospital — Athens, Greece
  • Errikos Dynan Hospital — Athens, Greece
  • University Hospital of Larissa — Larissa, Greece
  • Interbalkan Medical Center of Thessaloniki — Thessaloniki, Greece
  • Theageneion Anticancer Hospital — Thessaloniki, Greece
  • Ag. Loukas Hospital — Thessaloniki, Greece
  • Queen Mary Hospital — Hong Kong, Hong Kong
  • Tuen Mun Hospital — Hong Kong, Hong Kong
  • Queen Elizabeth Hospital Department of Clinical Oncology — Kowloon, Hong Kong
  • Prince of Wales Hosp — Shatin, Hong Kong
  • Orszagos Koranyi Pulmonologiai Intezet — Budapest, Hungary
  • Matrai Gyogyintezet — Mátraháza, Hungary
  • Pécsi Tudományegyetem — Pécs, Hungary
  • Református Pulmonológiai Centrum — Törökbálint, Hungary
  • St James Hospital — Dublin, Ireland
  • Beaumont Hospital — Dublin, Ireland
  • Tallaght Hospital — Dublin, Ireland
  • Mater Misecordiae University Hospital — Dublin, Ireland
  • Ospedale Giuseppe Moscati — Statte, Apulia, Italy
  • AORN Ospedali dei Colli Ospedale Monaldi — Naples, Campania, Italy
  • Istituto Nazionale Tumori Fondazione G. Pascale — Naples, Campania, Italy
  • A.O. Universitaria Policlinico Di Modena — Modena, Emilia-Romagna, Italy
  • Presidio san salvatore muraglia — Pesaro, Emilia-Romagna, Italy
  • Irccs Centro Di Riferimento Oncologico (CRO) — Aviano, Friuli Venezia Giulia, Italy
  • Azienda Ospedaliera San Camillo Forlanini — Rome, Lazio, Italy
  • Policlinico Universitario "Agostino Gemelli" — Rome, Lazio, Italy
  • IEO Istituto Europeo di Oncologia — Milan, Lombardy, Italy
  • Azienda Socio Sanitaria Territoriale Niguarda (Ospedale Niguarda Ca' Granda) — Milan, Lombardy, Italy
  • Azienda Ospedaliera San Gerardo di Monza — Monza MI, Lombardy, Italy
  • Humanitas Centro Catanese Di Oncologia — Misterbianco (CT), Sicily, Italy
  • USL 6 Toscana Nord Ovest ? P.O. Livorno — Livorno, Tuscany, Italy
  • Ospedale P. Pederzoli Casa di cura Privata — Peschiera Del Garda (VR), Veneto, Italy
  • Fujita Health University Hospital — Aichi, Japan
  • Kyushu University Hospital — Fukuoka, Japan
  • Kurume University Hospital — Fukuoka, Japan
  • Hakodate Goryoukaku Hospital — Hokkaido, Japan
  • Hyogo Medical University Hospital — Hyōgo, Japan
  • Kagoshima University Hospital — Kagoshima, Japan
  • Kanagawa Cancer Center — Kanagawa, Japan
  • Sendai Kousei Hospital — Miyagi, Japan
  • Niigata University Medical & Dental Hospital — Niigata, Japan
  • Okayama University Hospital — Okayama, Japan
  • Osaka Metropolitan University Hospital — Osaka, Japan
  • Kansai Medical University Hospital — Osaka, Japan
  • Kindai University Hospital — Osaka, Japan
  • Tohoku University Hospital — Sendai, Japan
  • Shizuoka Cancer Center — Shizuoka, Japan
  • National Cancer Center Hospital — Tokyo, Japan
  • Juntendo University Hospital — Tokyo, Japan
  • The Cancer Institute Hospital of JFCR — Tokyo, Japan
  • Tokyo Medical University Hospital — Tokyo, Japan
  • Wakayama Medical University Hospital — Wakayama, Japan
  • Hospital Civil de Guadalajara Fray Antonio Alcalde — Guadalajara, Jalisco, Mexico
  • ARKE Estudios Clínicos S.A. de C.V. — Mexico City, Mexico
  • Meander Medisch Centrum — Amersfoort, Utrecht, Netherlands
  • NKI The Netherlands Cancer Institute — Amsterdam, Netherlands
  • Ziekenhuis Rijnstate — Arnhem, Netherlands
  • Amphia Ziekenhuis — Breda, Netherlands
  • Ziekenhuis St. Jansdal — Harderwijk, Netherlands
  • Medisch Centrum Haaglanden, locatie Antoniushove — Leidschendam, Netherlands
  • Isala — Zwolle, Netherlands
  • Harbour Cancer and Wellness — Auckland, New Zealand
  • Wellington Hospital — Newtown, New Zealand
  • Centrum Pulmonologii i Torakochirurgii — Bystra, Poland
  • Uniwersyteckie Centrum Kliniczne — Gda?sk, Poland
  • Krakowski Szpital Specjalistyczny im sw.Jana Pawla II — Krakow, Poland
  • Uniwersytecki Szpital Kliniczny nr 4 w Lublinie — Lublin, Poland
  • Warminsko-Mazurskie Centrum Chorób P?uc w Olsztynie — Olsztyn, Poland
  • Wielkopolskie Centrum Pulmonologii i Torakochirurgii w Poznaniu — Poznan, Poland
  • Radomskie Centrum Onkologii — Radom, Poland
  • Instytut Gruzlicy I Chorob Pluc — Warsaw, Poland
  • Mazowiecki Szpital Onkologiczny — Wieliszew, Poland
  • Dolnoslaskie Centrum Chorob Pluc — Wroclaw, Poland
  • Hospital de Braga — Braga, Portugal
  • Hospital Beatriz Angelo — Loures, Portugal
  • IPO do Porto — Porto, Portugal
  • CHVNG/E_Unidade 1 — Vila Nova de Gaia, Portugal
  • National University Hospital — Singapore, Singapore
  • National Cancer Centre — Singapore, Singapore
  • Wits Donald Gordon Clinical Trial Centre — Parktown, South Africa
  • University of Pretoria Oncology Department — Pretoria, South Africa
  • Chris Hani Baragwanath Clinical Trial Site — Soweto, South Africa
  • Pusan National University Hospital — Busan, South Korea
  • Chungbuk National University Hospital — Cheongju-si, South Korea
  • Kyungpook National University Chilgok Hospital — Daegu, South Korea
  • The Catholic University of Korea, Seoul St. Mary's Hospital — Seoul, South Korea
  • Seoul National University Hospital — Seoul, South Korea
  • Korea University Guro Hospital — Seoul, South Korea
  • Hospital Universitario Son Espases — Palma de Mallorca, Balearic Islands, Spain
  • Hospital Universitario Marques de Valdecilla — Santander, Cantabria, Spain
  • Complejo Hospitalario Universitario Insular?Materno Infantil — Las Palmas de Gran Canaria, LAS Palmas, Spain
  • Clinica Universitaria de Navarra — Pamplona, Navarre, Spain
  • Hospital Universitari Vall d Hebron — Barcelona, Spain
  • Hospital Clinic i Provincial de Barcelona — Barcelona, Spain
  • Hospital de la Santa Creu i Sant Pau — Barcelona, Spain
  • ICO L'Hospitalet — Barcelona, Spain
  • Clinica Universidad de Navarra Madrid — Madrid, Spain
  • Hospital Ramon y Cajal — Madrid, Spain
  • Hospital Universitario 12 de Octubre — Madrid, Spain
  • Hospital Universitario La Paz — Madrid, Spain
  • Hospital Clinico Universitario Virgen de la Victoria — Málaga, Spain
  • Hospital Universitario Virgen Macarena — Seville, Spain
  • Hospital Clínico Universitario de Valencia — Valencia, Spain
  • Kantonsspital Baden — Baden, Switzerland
  • Universitaetsspital Basel — Basel, Switzerland
  • Kantonsspital Graubünden Medizin Onkologie — Chur, Switzerland
  • Hôpital Universitaire de Genève (HUG) — Geneva, Switzerland
  • Kaohsiung Medical University Chung-Ho Memorial Hospital — Kaohsiung City, Taiwan
  • E-DA Hospital — Kaohsiung City, Taiwan
  • Chung Shan Medical University Hospital — Taichung, Taiwan
  • National Taiwan University Hospital — Taipei, Taiwan
  • Taipei Medical University Hospital — Taipei, Taiwan
  • Taipei Veterans General Hospital — Taipei, Taiwan
  • National Taiwan University Cancer Center — Zhongzheng Dist., Taiwan
  • Blackpool Teaching Hospitals NHS Foundation Trust , Victoria Hospital — Blackpool, United Kingdom
  • Bristol Haematology & Oncology Centre — Bristol, United Kingdom
  • East Kent Hospitals University NHS Foundation Trust — Canterbury, United Kingdom
  • Velindre NHS Trust - Velindre Cancer Centre — Cardiff, United Kingdom
  • Hull University Teaching Hospitals NHS Trust — Hull, United Kingdom
  • Barts and the London NHS Trust — London, United Kingdom
  • Royal Marsden Hospital - Fulham — London, United Kingdom
  • Sarah Cannon Research Institute — London, United Kingdom
  • Maidstone and Tunbridge Wells NHS Trust — Maidstone, United Kingdom
  • Oxford University Hospitals NHS Trust - Churchill Hospital — Oxford, United Kingdom
  • Royal Marsden NHS Foundation Trust — Sutton, United Kingdom
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record