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RECRUITING Not applicable ClinicalTrials.gov

Exploring Neurophysiological Markers of Brain Health

Sponsor: The University of Texas at Dallas • ClinicalTrials.gov ID: NCT06731452

Registry updated: 2026-09-21
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Description

The combination of transcranial magnetic stimulation (TMS) and electroencephalography (EEG) has been suggested as a promising brain imaging tool for identifying biomarkers of brain health. In this pilot study, study investigators will explore the neurophysiological metrics of brain health with a non-invasive brain imaging technique, alongside behavioral and fMRI metrics collected through another study (NCT04869111).

Interventions

  • Strategic Memory Advanced Reasoning Training teaches meta-cognitive strategies for individuals to apply to their daily lives for improved performance (Behavioral)
    Online SMART is a curriculum that teaches strategies of how to use the brain better, in such a way that may improve brain health and performance. SMART strives to achieve optimal cognitive function realized by the brain's ability to efficiently manage complex information by abstracting its essential meaning rather than attempting to memorize details, and to prioritize the information in order to attend to the most relevant parts. Stress Solutions extends the SMART principles to relevant domains of stress and resilience.

Eligibility criteria

Inclusion Criteria: * Must be an active brain imaging participant in The BrainHealth Project (NCT04869111) * Minimum age of 22 * Fluent in English * Able to read \& hear information over a computer * Must pass an MRI safety screener to assess the presence of contraindicators for MRI compatibility (i.e., non-removable metal within/on the body, claustrophobia, pregnancy, non-correctable vision problems, head trauma, and CNS disease)or other standard requirements as determined by the Imaging Center. * Must pass a modified TMS Adult Safety Screen * Meet all criteria for study as determined by the study physician Exclusion Criteria: * A diagnosis of a neurodegenerative disease * A history of stroke, concussion, or brain injury that currently hinders them from functioning at their prior level * A diagnosis of autism spectrum disorder that currently hinders them from functioning independently. * Metallic brain implants or fragments (like a shunt, pacemaker, clips, coils, bullet fragments, cochlear implants) * Magnetically activated implants or electronically implanted devices * Medication pumps * Personal or family history of epilepsy, seizure(s), seizure disorder. * History of, or risk factors for syncope (fainting) * Report significant cognitive challenges * Report untreated health issues (like substance abuse, hypertension, hypo- or hyper-thyroidism) * Have claustrophobia

Conditions

Healthy Lifestyle Health-Related Behavior

Locations

  • Center for BrainHealth at The University of Texas at Dallas — Dallas, Texas, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record