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RECRUITING Not applicable ClinicalTrials.gov

An Individualized Online Home-Based Exercise Program for Improving Symptoms in Gynecologic Cancer Survivors

Sponsor: Emory University • ClinicalTrials.gov ID: NCT06709534

Registry updated: 2026-10-19
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Description

This clinical trial tests an individualized online home-based exercise program in gynecologic cancer survivors and its impact on gut microbiome (the bacteria and microorganisms that live in the digestive system) and symptoms such as pain, fatigue, sleep disturbance, depression, and cognitive impairment. These symptoms can significantly reduce the quality of life (QoL) and survival rate in this cancer population. Thus, promoting physical activity among cancer survivors may help mitigate these severe symptoms. Using online platforms such as Zoom can help participants access an individualized exercise program that meets their specific needs to engage in physical activity and decrease their symptom burden. Home-based exercise, by providing self-chosen time and location and low costs, can address some barriers to physical activity for cancer survivors. An individualized online home-based exercise program may be feasible, and may improve symptoms and quality of life in gynecologic cancer survivors.

Interventions

  • Exercise Intervention (Other)
    Participate in an individualized online home-based exercise intervention
  • Functional Assessment (Other)
    Complete functional capacity assessment
  • Medical Device Usage and Evaluation (Other)
    Wear an activity tracker
  • Questionnaire Administration (Other)
    Ancillary studies
  • Supportive Care (Other)
    Receive social support

Eligibility criteria

Inclusion Criteria: * Women aged ≥ 18 years old * Previously diagnosed with gynecologic cancer (e.g., uterine, ovarian, cervical) * Completed cancer treatment (chemotherapy or chemoradiation) * Able to read and speak English * Do not meet recommended exercise levels as defined by The American College of Sports Medicine Exclusion Criteria: * History of metastatic or other primary cancer * Serious mental health conditions (e.g., bipolar disorder, schizophrenia, major depression) * Certain chronic diseases (e.g., muscular-skeletal diseases that limit mobility, autoimmune diseases, uncontrolled diabetes, hypertension, renal disease (creatinine \> 2.5 mg/dL) * Unable to read/speak English

Conditions

Malignant Female Reproductive System Neoplasm

Locations

  • Grady Health System — Atlanta, Georgia, United States
  • Emory University Hospital Midtown — Atlanta, Georgia, United States
  • Emory University Hospital/Winship Cancer Institute — Atlanta, Georgia, United States
  • Emory Decatur Hospital — Decatur, Georgia, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record