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RECRUITING Phase 1 ClinicalTrials.gov

The Effects of Cannabidiol on the Driving Performance of Healthy Adults by Dose and Sex

Sponsor: West Virginia University • ClinicalTrials.gov ID: NCT06686914

Registry updated: 2026-10-06
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Description

The objectives/purpose of this study are to comprehensively investigate the effects of non-prescription CBD on driving performance, drowsiness, sedation, and cognitive function in a large sample of healthy adults aged 18-30 years, with additional characterization of effects by dose and by sex, using a rigorous RCT design which will naturally mitigate confounding factors.

Interventions

  • Cannabidiol (CBD) Oil 300mg (Drug)
    Cannabidiol (CBD) Oil 300mg, 1 dose
  • Cannabidiol (CBD) Oil 150mg (Drug)
    Cannabidiol (CBD) Oil 150mg, 1 dose
  • Placebo Oil (Drug)
    Placebo Oil, 1 dose

Eligibility criteria

Inclusion Criteria: * Possess a current drivers' license * Driven a motor vehicle at least once in the past 30 days * Able to read English * Test negative for all substances on a urine drug test and complete a test drive to ensure the absence of simulation sickness * Not taking any daily prescription medications (excluding birth control) * Not diagnosed with any serious chronic disease by a licensed healthcare provider (including but not limited to Alzheimer's and related dementias, Parkinson's disease or other neurodegenerative disorder, major depressive or anxiety disorder, schizophrenia or other serious mental illness, arrhythmias, cataracts, glaucoma, chronic obstructive pulmonary disease, diabetes, epilepsy, sleep apnea, and fibromyalgia) * Have an individual willing to drive them home after testing or be taken home by study staff after testing Exclusion Criteria: * Currently smoke, vape or use tobacco products, used CBD in the past 30 days * Used illegal drugs in the past 30 days (e.g., cocaine/crack, heroin, methamphetamine, 3,4-methylenedioxy-methamphetamine, inhalants, phencyclidine, lysergic acid diethylamide, psilocybin mushrooms, or marijuana) * Are pregnant or lactating at time of study

Conditions

Cannabidiol Effects Driving Performance

Locations

  • West Virginia University — Morgantown, West Virginia, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record