RECRUITING Not applicable ClinicalTrials.gov

Does Ethyl Chloride Spray Work?

Sponsor: University of Chicago • ClinicalTrials.gov ID: NCT06651788

Registry updated: 2026-10-08

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Description

A procedure frequently performed by orthopaedic providers is the administration of corticosteroid injections for the management of various soft tissues and joint-related conditions, such as osteoarthritis, tendinitis, carpal tunnel syndrome, trigger finger, and de Quervain's tenosynovitis. While these injections have demonstrated effectiveness in alleviating symptoms, the discomfort associated with the procedure can be a source of anxiety and apprehension for patients. This discomfort arises from the sensation of the needle entering the affected area and the burning sensation induced by the corticosteroid solution.

Interventions

Ethyl Chloride (Other)
Topical anesthetic that rapidly cools the skin and underlying tissues
Cold Saline Spray (Other)
placebo application of cold saline spray

Eligibility criteria

Inclusion Criteria: * 18 years and older * Receiving a corticosteroid injection in an upper or lower extremity (to include soft tissue and joint injections) Exclusion Criteria: * 17 years old and younger * declines enrollment

Conditions

Injection Fear Injection Pain Prevention Injection Complication

Locations

University of Chicago — Chicago, Illinois, United States

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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

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