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Monitoring and Optimization of Cerebral Perfusion Pressure in Post-cardiac Arrest Patients: a Pilot Study

Sponsor: National Taiwan University Hospital • ClinicalTrials.gov ID: NCT06601842

Registry updated: 2026-09-18

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Description

The goal of this study is to establish the ICP and CPP monitoring process and analyze the results in post-arrest patients, to validate the correlation between direct and non-invasive ICP monitoring indicators, to establish a protocol of management of elevated ICP and insufficient CPP in post-arrest care, to establish a protocol for personalizing CPP and MAP optimization, and to analyze its impact on neuroprognosis. Participants will receive ICP monitoring within 12 hours post-ROSC if meet all inclusion and exclusion criteria.

Interventions

ICP monitoring (Device)
ICP monitoring

Eligibility criteria

Inclusion Criteria: * non-traumatic cardiac arrest * admitted to ICU * GCS: motor \<=5 * severity: TIMECARD score medium-risk group Exclusion Criteria: * traumatic cardiac arrest * pregnancy * intracranial hemorrhage * coagulopathy * anti-platelet or anti-coagulation use * terminal illness * pre-arrest CPC score \>=3 * GWR \< 1.2 on CT or severe hypoxic ischemic encephalopathy * CNS infection

Conditions

Cardiac Arrest

Locations

National Taiwan University Hospital — Taipei, Taiwan

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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

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