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RECRUITING Not applicable ClinicalTrials.gov

Michigan Split-belt Treadmill Training Program to Improve Long-Term Knee Biomechanics After ACL Reconstruction

Sponsor: University of Michigan • ClinicalTrials.gov ID: NCT06529692

Registry updated: 2026-09-15
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Description

The goal of this study is to gather pilot data to help inform a future clinical trial. As such, the investigators will employ a randomized clinical trial design, but data will only be collected on 9 total subjects. Nine subjects will be randomized to 2 split-belt intervention groups (one group where early stance loading is trained and the other where midstance loading is trained) and a placebo group. The goal of this study is to explore the adaptations in knee loading from a 6-week split-belt training intervention. The investigators' main question for this aim is: 1. Does knee loading, measured by the sagittal plane knee moment, change to a greater extent in the split-belt treadmill training groups compared to the placebo group? 2. Are there differences in training-related knee loading changes between individuals trained in the early stance vs. midstance loading split-belt training?

Interventions

  • Placebo Split-Belt Training (Behavioral)
    Walking on a split-belt treadmill in which the belt under the ACL leg will move at a speed that is minimally slower than the other belt.
  • Split-Belt Training (Behavioral)
    Walking on a split-belt treadmill in which the treadmill belt under the ACL leg will move at a speed faster or slower than the belt under the Non-ACL leg.

Eligibility criteria

Inclusion Criteria: * aged 14-45 years * suffered an acute, complete ACL rupture as confirmed by MRI and physical exam * have undergone ACL reconstruction w autograft within the past 10 months * willingness to participate in testing and follow-up as outlined in the protocol * English-speaking Exclusion Criteria: * inability to provide written informed consent * female subjects who are pregnant or are planning to become pregnant (self-reported) * previous ACL injury * previous surgery to either knee * bony fracture accompanying ACL injury * patients who experienced a knee dislocation * patients who had their ACL reconstructed with an allograft * patients who underwent a multi-ligamentous and/or staged ACL reconstruction

Conditions

ACL Anterior Cruciate Ligament ACL Injury

Locations

  • University of Michigan — Ann Arbor, Michigan, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record