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RECRUITING Phase 3 ClinicalTrials.gov

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

Sponsor: National Cancer Institute (NCI) • ClinicalTrials.gov ID: NCT06498635

Registry updated: 2026-10-19
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Description

This phase III trial compares durvalumab to the usual approach (patient observation) after surgery for the treatment of patients with early-stage non-small cell lung cancer. Immunotherapy with monoclonal antibodies, such as durvalumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. The usual approach for patients who are not in a study is to closely watch a patient's condition after surgery and to have regular visits with their doctor to watch for signs of the cancer coming back. Usually, patients do not receive further treatment unless the cancer returns. This study will help determine whether this different approach with durvalumab is better, the same, or worse than the usual approach of observation. Giving durvalumab may help patients live longer and prevent early-stage non-small cell lung cancer from coming back as compared to the usual approach.

Interventions

  • Biospecimen Collection (Procedure)
    Undergo blood sample collection
  • Computed Tomography (Procedure)
    Undergo CT
  • Durvalumab (Biological)
    Given IV
  • Patient Observation (Other)
    Undergo active surveillance
  • Questionnaire Administration (Other)
    Ancillary studies

Eligibility criteria

Inclusion Criteria: * Participants must have histologically or cytological confirmed diagnosis of clinical stage II-IIIB (excluding clinical N3 disease) non-small cell lung cancer (NSCLC) * Participants must have had a complete (R0) resection of NSCLC (with appropriate lymph node sampling as defined by the National Comprehensive Cancer Network \[NCCN\] guidelines) within 84 days (12 weeks) prior to randomization. Acceptable types of surgical resection are: lobectomy, sleeve resection, bi-lobectomy, or pneumonectomy. Wedge resection is not allowed. * Note the NCCN guidelines: N1 and N2 node resection and mapping is a routine component of lung cancer resections. It is recommended at a minimum one N1 and three N2 stations is sampled or complete lymph node dissection. Formal ipsilateral mediastinal lymph node dissection is indicated for participants undergoing resection for N2 disease * Participants must have a pathologic complete response (pCR) (no viable tumor in the resected specimen or lymph nodes), as determined by local pathology review * Participants must have a PD-L1 status result (e.g. \[\< 1% versus \>= 1% or unknown\]) * Participants must not have known EGFR mutations, or ALK gene fusion * Participants must have received at least two cycles of neoadjuvant platinum-based chemotherapy and anti-PD-1 or anti-PD-L1 therapy. The neoadjuvant treatment must be Food and Drug Administration (FDA) approved and standard of care as listed in NCCN guidelines * Participants must not be planning to receive any concurrent non-protocol directed chemotherapy, immunotherapy, biologic or hormonal therapy for NSCLC treatment while receiving treatment on this study * Participants must not have received any prior systemic therapy (systemic chemotherapy, immunotherapy or investigational drug) within 28 days prior to randomization * Participants must not have medical contraindications or severe adverse events to receiving anti-PD-1 or anti-PD-L1 therapy * Participants must not have received post-operative radiation therapy (PORT) for NSCLC * Participants must not have any unresolved toxicity National Cancer Institute (NCI) CTCAE grade ≥ 2 from previous anticancer therapy with the exception of alopecia, and vitiligo. Note, participants with grade ≥2 neuropathy may be included at the discretion of the treating investigator. Note, participants with irreversible toxicity not reasonably expected to be exacerbated by treatment with durvalumab may be included at the discretion of the treating investigator * Participant must be ≥ 18 years old at time of study entry * Participants must have body weight \> 30 kg * Participant must have Zubrod performance status of 0-2 * Participant must have a complete medical history and physical exam within 28 days prior to randomization * Hemoglobin \> 9.0 g/dL (within 28 days prior to randomization) * Absolute neutrophil count ≥ 1.5 x 10\^3/uL (within 28 days prior to randomization) * Platelets ≥ 100 x 10\^3/uL (within 28 days prior to randomization) * Total bilirubin ≤ 1 x institutional upper limit of normal (ULN) unless history of Gilbert's disease. Participants with history of Gilbert's disease must have total bilirubin ≤ 5 x institutional ULN (within 28 days prior to randomization) * Aspartate transaminase (AST)/alanine transaminase (ALT) ≤ 3 × institutional ULN (within 28 days prior to randomization) * Participants must have a calculated creatinine clearance ≥ 40 mL/min using the following Cockcroft-Gault formula. This specimen must have been drawn and processed within 28 days prior to randomization. For creatinine clearance formula see the tools on the Clinical Research Associate (CRA) Workbench https://txwb.crab.org/TXWB/Tools.aspx * Participants must have fully recovered from the effects of prior surgery in the opinion of the treating investigator * Participants with a known history of human immunodeficiency virus (HIV)-infection must be on effective anti-retroviral therapy at registration and have undetectable viral load test on the most recent test results obtained within 6 months prior to randomization * Participants with a known history of chronic hepatitis B virus (HBV) infection must have undetectable HBV viral load while on suppressive therapy on the most recent test results obtained within 6 months prior to randomization, if indicated * Participants with a known history of hepatitis C virus (HCV) infection must have been treated and cured. Participants currently being treated for HCV infection must have undetectable HCV viral load test on the most recent test results obtained within 6 months prior to randomization, if indicated * Participants must not have had an organ transplant * Participants must not have a prior or concurrent malignancy whose natural history or treatment (in the opinion of the treating physician) has the potential to interfere with the safety or efficacy assessment of the investigational regimen * Participant must not have medical contraindications to receiving immunotherapy, including history of non-infectious pneumonitis that required steroids or active autoimmune disease that has required systemic treatment with disease modifying agents, corticosteroids or immunosuppressive drugs in the past two years. Replacement therapy (e.g. thyroxine for pre-existing hypothyroidism, insulin for type I diabetes mellitus, or physiologic corticosteroid replacement therapy for adrenal or pituitary insufficiency, etc.) is not considered a form of systemic treatment. Intra-articular steroid injections are allowed * Participants must not be pregnant or nursing (nursing includes breast milk fed to an infant by any means, including from the breast, milk expressed by hand, or pumped). Individuals who are of reproductive potential must have agreed to use an effective contraceptive method during protocol therapy and for 6 months following completion of protocol therapy with details provided as a part of the consent process. A person who has had menses at any time in the preceding 12 consecutive months or who has semen likely to contain sperm is considered to be of "reproductive potential." In addition to routine contraceptive methods, "effective contraception" also includes refraining from sexual activity that might result in pregnancy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) including hysterectomy, bilateral oophorectomy, bilateral tubal ligation/occlusion, and vasectomy with testing showing no sperm in the semen. Participants should not breastfeed during protocol therapy and for 6 months following completion of protocol therapy * Participants must not have received a live or live attenuated vaccine within 28 days prior randomization. Examples of live vaccines include, but are not limited to, the following: measles, mumps, rubella, varicella/zoster, yellow fever rabies, Bacillus Calmette-Guerin (BCG) and typhoid vaccine. Seasonal influenza vaccines and coronavirus disease 19 (COVID-19) vaccines are allowed, however, intranasal influenza vaccines (e.g. Flu-Mist) are live attenuated, and are not allowed * Participants must be offered the opportunity to participate in specimen banking * Participants who can complete FACT-L, FACT-BRM, and PRO-CTCAE questionnaires forms in English, or Spanish must agree to participate in the patient-reported outcome study * NOTE: As a part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system * Participants must be informed of the investigational nature of this study and must sign and give informed consent in accordance with institutional and federal guidelines * For participants with impaired decision-making capabilities, legally authorized representatives may sign and give informed consent on behalf of study participants in accordance with applicable federal, local, and Central Institutional Review Board (CIRB) regulations

Conditions

Lung Non-Small Cell Carcinoma Stage II Lung Cancer AJCC v8 Stage IIIA Lung Cancer AJCC v8 Stage IIIB Lung Cancer AJCC v8

Locations

  • NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro — Jonesboro, Arkansas, United States
  • Tower Cancer Research Foundation — Beverly Hills, California, United States
  • Kaiser Permanente Dublin — Dublin, California, United States
  • Kaiser Permanente-Fremont — Fremont, California, United States
  • Kaiser Permanente Fresno Orchard Plaza — Fresno, California, United States
  • UC San Diego Moores Cancer Center — La Jolla, California, United States
  • Veterans Affairs Loma Linda Healthcare System — Loma Linda, California, United States
  • Cedars-Sinai Medical Center — Los Angeles, California, United States
  • Kaiser Permanente- Modesto MOB II — Modesto, California, United States
  • Kaiser Permanente-Oakland — Oakland, California, United States
  • Kaiser Permanente-Roseville — Roseville, California, United States
  • Kaiser Permanente Downtown Commons — Sacramento, California, United States
  • University of California Davis Comprehensive Cancer Center — Sacramento, California, United States
  • Kaiser Permanente-South Sacramento — Sacramento, California, United States
  • Kaiser Permanente-San Francisco — San Francisco, California, United States
  • Kaiser Permanente-Santa Teresa-San Jose — San Jose, California, United States
  • Kaiser Permanente San Leandro — San Leandro, California, United States
  • Kaiser San Rafael-Gallinas — San Rafael, California, United States
  • Kaiser Permanente Medical Center - Santa Clara — Santa Clara, California, United States
  • Kaiser Permanente-Santa Rosa — Santa Rosa, California, United States
  • Kaiser Permanente-South San Francisco — South San Francisco, California, United States
  • Torrance Memorial Physician Network - Cancer Care — Torrance, California, United States
  • Kaiser Permanente-Vallejo — Vallejo, California, United States
  • Kaiser Permanente-Walnut Creek — Walnut Creek, California, United States
  • Kaiser Permanente-Franklin — Denver, Colorado, United States
  • Saint Mary's Hospital and Regional Medical Center — Grand Junction, Colorado, United States
  • Kaiser Permanente-Rock Creek — Lafayette, Colorado, United States
  • Kaiser Permanente-Lone Tree — Lone Tree, Colorado, United States
  • Hartford HealthCare - Avon — Avon, Connecticut, United States
  • Hartford Hospital — Hartford, Connecticut, United States
  • Hartford HealthCare - Manchester — Manchester, Connecticut, United States
  • Midstate Medical Center — Meriden, Connecticut, United States
  • The Hospital of Central Connecticut — New Britain, Connecticut, United States
  • Beebe South Coastal Health Campus — Millville, Delaware, United States
  • Helen F Graham Cancer Center — Newark, Delaware, United States
  • Medical Oncology Hematology Consultants PA — Newark, Delaware, United States
  • Beebe Health Campus — Rehoboth Beach, Delaware, United States
  • Morton Plant Hospital — Clearwater, Florida, United States
  • Miami Cancer Institute — Miami, Florida, United States
  • South Florida Baptist Hospital — Plant City, Florida, United States
  • Saint Anthony's Hospital Cancer Care Center — St. Petersburg, Florida, United States
  • Moffitt Cancer Center-International Plaza — Tampa, Florida, United States
  • Saint Joseph's Hospital/Children's Hospital-Tampa — Tampa, Florida, United States
  • Moffitt Cancer Center - McKinley Campus — Tampa, Florida, United States
  • Moffitt Cancer Center — Tampa, Florida, United States
  • Winter Haven Hospital — Winter Haven, Florida, United States
  • Emory University Hospital Midtown — Atlanta, Georgia, United States
  • Emory University Hospital/Winship Cancer Institute — Atlanta, Georgia, United States
  • Emory Saint Joseph's Hospital — Atlanta, Georgia, United States
  • Emory Decatur Hospital — Decatur, Georgia, United States
  • Emory Johns Creek Hospital — Johns Creek, Georgia, United States
  • Hawaii Cancer Care Inc - Waterfront Plaza — Honolulu, Hawaii, United States
  • Queen's Cancer Cenrer - POB I — Honolulu, Hawaii, United States
  • Queen's Medical Center — Honolulu, Hawaii, United States
  • Queen's Cancer Center - Kuakini — Honolulu, Hawaii, United States
  • Kaiser Permanente Moanalua Medical Center — Honolulu, Hawaii, United States
  • Hawaii Cancer Care - Westridge — ‘Aiea, Hawaii, United States
  • The Queen's Medical Center - West Oahu — ‘Ewa Beach, Hawaii, United States
  • Saint Luke's Cancer Institute - Boise — Boise, Idaho, United States
  • Kootenai Health - Coeur d'Alene — Coeur d'Alene, Idaho, United States
  • Saint Luke's Cancer Institute - Fruitland — Fruitland, Idaho, United States
  • Saint Luke's Cancer Institute - Meridian — Meridian, Idaho, United States
  • Saint Alphonsus Cancer Care Center-Nampa — Nampa, Idaho, United States
  • Saint Luke's Cancer Institute - Nampa — Nampa, Idaho, United States
  • Kootenai Clinic Cancer Services - Post Falls — Post Falls, Idaho, United States
  • Kootenai Clinic Cancer Services - Sandpoint — Sandpoint, Idaho, United States
  • Northwestern University — Chicago, Illinois, United States
  • Northwestern Medicine Cancer Center Kishwaukee — DeKalb, Illinois, United States
  • Northwestern Medicine Cancer Center Delnor — Geneva, Illinois, United States
  • Northwestern Medicine Glenview Outpatient Center — Glenview, Illinois, United States
  • Northwestern Medicine Grayslake Outpatient Center — Grayslake, Illinois, United States
  • Northwestern Medicine Huntley Hospital — Huntley, Illinois, United States
  • Northwestern Medicine Lake Forest Hospital — Lake Forest, Illinois, United States
  • Loyola University Medical Center — Maywood, Illinois, United States
  • Northwestern Medicine Oak Brook — Oak Brook, Illinois, United States
  • Northwestern Medicine Orland Park — Orland Park, Illinois, United States
  • Northwestern Medicine Cancer Center Warrenville — Warrenville, Illinois, United States
  • IU Health West Hospital — Avon, Indiana, United States
  • IU Health North Hospital — Carmel, Indiana, United States
  • Indiana University/Melvin and Bren Simon Cancer Center — Indianapolis, Indiana, United States
  • Sidney and Lois Eskenazi Hospital — Indianapolis, Indiana, United States
  • Mary Greeley Medical Center — Ames, Iowa, United States
  • McFarland Clinic - Ames — Ames, Iowa, United States
  • UI Health Care Mission Cancer and Blood - Ankeny Clinic — Ankeny, Iowa, United States
  • McFarland Clinic - Boone — Boone, Iowa, United States
  • Saint Anthony Regional Hospital — Carroll, Iowa, United States
  • UI Health Care Mission Cancer and Blood - West Des Moines Clinic — Clive, Iowa, United States
  • Iowa Methodist Medical Center — Des Moines, Iowa, United States
  • UI Health Care Mission Cancer and Blood - Des Moines Clinic — Des Moines, Iowa, United States
  • Broadlawns Medical Center — Des Moines, Iowa, United States
  • Mercy Medical Center - Des Moines — Des Moines, Iowa, United States
  • UI Health Care Mission Cancer and Blood - Laurel Clinic — Des Moines, Iowa, United States
  • McFarland Clinic - Trinity Cancer Center — Fort Dodge, Iowa, United States
  • UI Healthcare Mission Cancer and Blood - Fort Dodge — Fort Dodge, Iowa, United States
  • McFarland Clinic - Jefferson — Jefferson, Iowa, United States
  • McFarland Clinic - Marshalltown — Marshalltown, Iowa, United States
  • UI Health Care Mission Cancer and Blood - Waukee Clinic — Waukee, Iowa, United States
  • HaysMed — Hays, Kansas, United States
  • Lawrence Memorial Hospital — Lawrence, Kansas, United States
  • The University of Kansas Cancer Center - Olathe — Olathe, Kansas, United States
  • Salina Regional Health Center — Salina, Kansas, United States
  • University of Kansas Health System Saint Francis Campus — Topeka, Kansas, United States
  • University Medical Center New Orleans — New Orleans, Louisiana, United States
  • Harold Alfond Center for Cancer Care — Augusta, Maine, United States
  • MaineHealth Maine Medical Center- Scarborough — Scarborough, Maine, United States
  • MaineHealth Cancer Care and IV Therapy - South Portland — South Portland, Maine, United States
  • UM Upper Chesapeake Hematology and Oncology - Aberdeen — Aberdeen, Maryland, United States
  • Johns Hopkins University/Sidney Kimmel Cancer Center — Baltimore, Maryland, United States
  • UPMC Western Maryland — Cumberland, Maryland, United States
  • Beverly Hospital — Beverly, Massachusetts, United States
  • Lahey Clinic — Burlington, Massachusetts, United States
  • Addison Gilbert Hospital — Gloucester, Massachusetts, United States
  • Lahey Clinic Peabody — Peabody, Massachusetts, United States
  • Baystate Medical Center — Springfield, Massachusetts, United States
  • UMass Memorial Medical Center - University Campus — Worcester, Massachusetts, United States
  • University of Michigan Rogel Cancer Center — Ann Arbor, Michigan, United States
  • Bronson Battle Creek — Battle Creek, Michigan, United States
  • Trinity Health IHA Medical Group Hematology Oncology - Brighton — Brighton, Michigan, United States
  • University of Michigan - Brighton Center for Specialty Care — Brighton, Michigan, United States
  • Trinity Health IHA Medical Group Hematology Oncology - Canton — Canton, Michigan, United States
  • Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital — Chelsea, Michigan, United States
  • Henry Ford Macomb Hospital-Clinton Township — Clinton Township, Michigan, United States
  • Henry Ford Hospital — Detroit, Michigan, United States
  • Henry Ford Health Saint John Hospital — Detroit, Michigan, United States
  • Henry Ford River District Hospital — East China Township, Michigan, United States
  • OSF Saint Francis Hospital and Medical Group — Escanaba, Michigan, United States
  • Cancer Hematology Centers - Flint — Flint, Michigan, United States
  • Genesee Hematology Oncology PC — Flint, Michigan, United States
  • Genesys Hurley Cancer Institute — Flint, Michigan, United States
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital — Grand Rapids, Michigan, United States
  • Trinity Health Grand Rapids Hospital — Grand Rapids, Michigan, United States
  • Henry Ford Saint John Hospital - Academic — Grosse Pointe Woods, Michigan, United States
  • Henry Ford Saint John Hospital - Breast — Grosse Pointe Woods, Michigan, United States
  • Henry Ford Saint John Hospital - Van Elslander — Grosse Pointe Woods, Michigan, United States
  • Bronson Methodist Hospital — Kalamazoo, Michigan, United States
  • West Michigan Cancer Center — Kalamazoo, Michigan, United States
  • University of Michigan Health - Sparrow Lansing — Lansing, Michigan, United States
  • Trinity Health Saint Mary Mercy Livonia Hospital — Livonia, Michigan, United States
  • Henry Ford Saint John Hospital - Macomb Medical — Macomb, Michigan, United States
  • Henry Ford Warren Hospital - Breast Macomb — Macomb, Michigan, United States
  • Trinity Health Muskegon Hospital — Muskegon, Michigan, United States
  • Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan, United States
  • Cancer and Hematology Centers of Western Michigan - Norton Shores — Norton Shores, Michigan, United States
  • Henry Ford Health Providence Novi Hospital — Novi, Michigan, United States
  • Trinity Health Saint Joseph Mercy Oakland Hospital — Pontiac, Michigan, United States
  • Corewell Health Reed City Hospital — Reed City, Michigan, United States
  • Corewell Health William Beaumont University Hospital — Royal Oak, Michigan, United States
  • Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center — Saint Joseph, Michigan, United States
  • Corewell Health Lakeland Hospitals - Saint Joseph Hospital — Saint Joseph, Michigan, United States
  • Henry Ford Health Providence Southfield Hospital — Southfield, Michigan, United States
  • Munson Medical Center — Traverse City, Michigan, United States
  • Corewell Health Beaumont Troy Hospital — Troy, Michigan, United States
  • Henry Ford Health Warren Hospital — Warren, Michigan, United States
  • Henry Ford Madison Heights Hospital - Breast — Warren, Michigan, United States
  • Henry Ford Warren Hospital - GLCMS — Warren, Michigan, United States
  • University of Michigan Health - West — Wyoming, Michigan, United States
  • Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus — Ypsilanti, Michigan, United States
  • Sanford Joe Lueken Cancer Center — Bemidji, Minnesota, United States
  • Essentia Health Saint Joseph's Medical Center — Brainerd, Minnesota, United States
  • Mercy Hospital — Coon Rapids, Minnesota, United States
  • Essentia Health - Deer River Clinic — Deer River, Minnesota, United States
  • Essentia Health Cancer Center — Duluth, Minnesota, United States
  • Fairview Southdale Hospital — Edina, Minnesota, United States
  • Minnesota Oncology - Edina — Edina, Minnesota, United States
  • Essentia Health Hibbing Clinic — Hibbing, Minnesota, United States
  • Abbott-Northwestern Hospital — Minneapolis, Minnesota, United States
  • Minneapolis VA Medical Center — Minneapolis, Minnesota, United States
  • Park Nicollet Clinic - Saint Louis Park — Saint Louis Park, Minnesota, United States
  • Regions Hospital — Saint Paul, Minnesota, United States
  • United Hospital — Saint Paul, Minnesota, United States
  • Essentia Health Sandstone — Sandstone, Minnesota, United States
  • Essentia Health Virginia Clinic — Virginia, Minnesota, United States
  • Baptist Memorial Hospital and Cancer Center-Golden Triangle — Columbus, Mississippi, United States
  • Baptist Cancer Center-Grenada — Grenada, Mississippi, United States
  • University of Mississippi Medical Center — Jackson, Mississippi, United States
  • Baptist Memorial Hospital and Cancer Center-Union County — New Albany, Mississippi, United States
  • Baptist Memorial Hospital and Cancer Center-Oxford — Oxford, Mississippi, United States
  • Baptist Memorial Hospital and Cancer Center-Desoto — Southhaven, Mississippi, United States
  • Mercy Oncology and Hematology - Clayton-Clarkson — Ballwin, Missouri, United States
  • University Health Truman Medical Center — Kansas City, Missouri, United States
  • Mercy Hospital South — St Louis, Missouri, United States
  • Mercy Hospital Saint Louis — St Louis, Missouri, United States
  • Community Hospital of Anaconda — Anaconda, Montana, United States
  • Billings Clinic Cancer Center — Billings, Montana, United States
  • Saint Vincent Frontier Cancer Center — Billings, Montana, United States
  • Bozeman Health Deaconess Hospital — Bozeman, Montana, United States
  • Benefis Sletten Cancer Institute — Great Falls, Montana, United States
  • Logan Health Medical Center — Kalispell, Montana, United States
  • Community Medical Center — Missoula, Montana, United States
  • University of New Mexico Cancer Center — Albuquerque, New Mexico, United States
  • Roswell Park Cancer Institute — Buffalo, New York, United States
  • Montefiore Medical Center-Einstein Campus — The Bronx, New York, United States
  • Montefiore Medical Center-Weiler Hospital — The Bronx, New York, United States
  • Montefiore Medical Center - Moses Campus — The Bronx, New York, United States
  • James J Peters VA Medical Center — The Bronx, New York, United States
  • Duke Cancer Center Cary — Cary, North Carolina, United States
  • Durham VA Medical Center — Durham, North Carolina, United States
  • Duke University Medical Center — Durham, North Carolina, United States
  • FirstHealth of the Carolinas-Moore Regional Hospital — Pinehurst, North Carolina, United States
  • Duke Cancer Center Raleigh — Raleigh, North Carolina, United States
  • Sanford Bismarck Medical Center — Bismarck, North Dakota, United States
  • Essentia Health Cancer Center-South University Clinic — Fargo, North Dakota, United States
  • Sanford Broadway Medical Center — Fargo, North Dakota, United States
  • Sanford Roger Maris Cancer Center — Fargo, North Dakota, United States
  • Aultman Health Foundation — Canton, Ohio, United States
  • Miami Valley Hospital South — Centerville, Ohio, United States
  • Ohio State University Comprehensive Cancer Center — Columbus, Ohio, United States
  • Miami Valley Hospital — Dayton, Ohio, United States
  • Miami Valley Hospital North — Dayton, Ohio, United States
  • Atrium Medical Center-Middletown Regional Hospital — Franklin, Ohio, United States
  • Miami Valley Cancer Care and Infusion — Greenville, Ohio, United States
  • Upper Valley Medical Center — Troy, Ohio, United States
  • University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma, United States
  • Providence Hood River Memorial Hospital — Hood River, Oregon, United States
  • Providence Newberg Medical Center — Newberg, Oregon, United States
  • Providence Willamette Falls Medical Center — Oregon City, Oregon, United States
  • Providence Portland Medical Center — Portland, Oregon, United States
  • Providence Saint Vincent Medical Center — Portland, Oregon, United States
  • Oregon Health and Science University — Portland, Oregon, United States
  • Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania, United States
  • Lehigh Valley Hospital - Muhlenberg — Bethlehem, Pennsylvania, United States
  • Bryn Mawr Hospital — Bryn Mawr, Pennsylvania, United States
  • Pocono Medical Center — East Stroudsburg, Pennsylvania, United States
  • UPMC Hillman Cancer Center Erie — Erie, Pennsylvania, United States
  • UPMC Cancer Centers - Arnold Palmer Pavilion — Greensburg, Pennsylvania, United States
  • UPMC Pinnacle Cancer Center/Community Osteopathic Campus — Harrisburg, Pennsylvania, United States
  • Lehigh Valley Hospital-Hazleton — Hazleton, Pennsylvania, United States
  • UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion — Mechanicsburg, Pennsylvania, United States
  • Riddle Memorial Hospital — Media, Pennsylvania, United States
  • UPMC Hillman Cancer Center - Monroeville — Monroeville, Pennsylvania, United States
  • Paoli Memorial Hospital — Paoli, Pennsylvania, United States
  • Thomas Jefferson University Hospital — Philadelphia, Pennsylvania, United States
  • Jefferson Torresdale Hospital — Philadelphia, Pennsylvania, United States
  • UPMC Hillman Cancer Center — Pittsburgh, Pennsylvania, United States
  • Reading Hospital — West Reading, Pennsylvania, United States
  • Lankenau Medical Center — Wynnewood, Pennsylvania, United States
  • Prisma Health Cancer Institute - Spartanburg — Boiling Springs, South Carolina, United States
  • Prisma Health Cancer Institute - Easley — Easley, South Carolina, United States
  • Gibbs Cancer Center-Gaffney — Gaffney, South Carolina, United States
  • Tidelands Georgetown Memorial Hospital — Georgetown, South Carolina, United States
  • Prisma Health Cancer Institute - Butternut — Greenville, South Carolina, United States
  • Prisma Health Cancer Institute - Faris — Greenville, South Carolina, United States
  • Prisma Health Cancer Institute - Eastside — Greenville, South Carolina, United States
  • Prisma Health Cancer Institute - Greer — Greer, South Carolina, United States
  • Gibbs Cancer Center-Pelham — Greer, South Carolina, United States
  • Prisma Health Cancer Institute - Seneca — Seneca, South Carolina, United States
  • Spartanburg Medical Center — Spartanburg, South Carolina, United States
  • SMC Center for Hematology Oncology Union — Union, South Carolina, United States
  • Sanford Cancer Center Oncology Clinic — Sioux Falls, South Dakota, United States
  • Sanford USD Medical Center - Sioux Falls — Sioux Falls, South Dakota, United States
  • Baptist Memorial Hospital and Cancer Center-Collierville — Collierville, Tennessee, United States
  • Baptist Memorial Hospital and Cancer Center-Memphis — Memphis, Tennessee, United States
  • Hematology Oncology Associates of Fredericksburg Inc — Fredericksburg, Virginia, United States
  • Centra Alan B Pearson Regional Cancer Center — Lynchburg, Virginia, United States
  • Virginia Cancer Institute — Richmond, Virginia, United States
  • VCU Community Memorial Health Center — South Hill, Virginia, United States
  • Swedish Cancer Institute-Edmonds — Edmonds, Washington, United States
  • Swedish Cancer Institute-Issaquah — Issaquah, Washington, United States
  • Swedish Medical Center-First Hill — Seattle, Washington, United States
  • Edwards Comprehensive Cancer Center — Huntington, West Virginia, United States
  • Aspirus Cancer Care-Antigo-Volm Cancer Center — Antigo, Wisconsin, United States
  • Duluth Clinic Ashland — Ashland, Wisconsin, United States
  • Marshfield Medical Center-EC Cancer Center — Eau Claire, Wisconsin, United States
  • Saint Vincent Hospital Cancer Center Green Bay — Green Bay, Wisconsin, United States
  • Saint Vincent Hospital Cancer Center at Saint Mary's — Green Bay, Wisconsin, United States
  • Gundersen Lutheran Medical Center — La Crosse, Wisconsin, United States
  • Marshfield Medical Center-Marshfield — Marshfield, Wisconsin, United States
  • Aspirus Medford Hospital — Medford, Wisconsin, United States
  • ProHealth D N Greenwald Center — Mukwonago, Wisconsin, United States
  • ProHealth Oconomowoc Memorial Hospital — Oconomowoc, Wisconsin, United States
  • Saint Vincent Hospital Cancer Center at Oconto Falls — Oconto Falls, Wisconsin, United States
  • Aspirus Cancer Care-Rhinelander-James Beck Cancer Center — Rhinelander, Wisconsin, United States
  • Saint Vincent Hospital Cancer Center at Sheboygan — Sheboygan, Wisconsin, United States
  • Sheboygan Physicians Group — Sheboygan, Wisconsin, United States
  • Aspirus Cancer Care - Stevens Point — Stevens Point, Wisconsin, United States
  • Marshfield Medical Center-River Region at Stevens Point — Stevens Point, Wisconsin, United States
  • Saint Vincent Hospital Cancer Center at Sturgeon Bay — Sturgeon Bay, Wisconsin, United States
  • UW Cancer Center at ProHealth Care — Waukesha, Wisconsin, United States
  • Aspirus Cancer Care-Wausau — Wausau, Wisconsin, United States
  • Marshfield Medical Center - Weston — Weston, Wisconsin, United States
  • Aspirus Cancer Care - Wisconsin Rapids — Wisconsin Rapids, Wisconsin, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record