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RECRUITING Not applicable ClinicalTrials.gov

Enhancing Attention and Wellbeing Using Digital Therapeutics

Sponsor: University of California, San Francisco • ClinicalTrials.gov ID: NCT06397469

Registry updated: 2026-08-24
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Description

The goals of the proposed research are to first determine the minimal and/or optimal dose of a digital intervention required for cognitive enhancement, and then to examine the impact of several potential moderators of treatment effects (i.e., cognitive decline, AD polygenic hazard score, cardiovascular risk, and race/ethnicity). This knowledge gained from his high-impact study with transform the field of cognitive interventions, paving the way for a precision medicine model for cognitive enhancing interventions that improve quality of life for older adults and individuals with cognitive deficits at risk of developing dementia.

Interventions

  • MediTrain (Device)
    MediTrain is a tablet-based, meditation-inspired, cognitive training game aimed at improving self-regulation of internal attention and distractions. It was developed in collaboration with meditation thought-leader Jack Kornfield, and Zynga, a world-class video game company. It was created to make benefits of concentrative meditation more easily accessible to anyone, including complete novices. This is achieved by creating a game that yields quantifiable and attainable goals, provides feedback, and includes an adaptive algorithm to gradually increase difficulty as users improve.
  • Worder (Device)
    Worder was designed to enhance visual motor and visual spatial skills in individuals of all ages and cognitive abilities. Visual processing is required for all cognitive abilities that involve vision including attention, working memory, and task management. Worder's goal is to improve cognitive function more broadly by developing this critical skill underlying multiple abilities.

Eligibility criteria

Inclusion Criteria: * 60+ years old (adult) * English language fluency * owning a smartphone or tablet Exclusion Criteria: * Under 60 years old (minor)

Conditions

Aging MCI Cognitive Decline

Locations

  • University of California San Francisco — San Francisco, California, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record