Niraparib Maintenance in HRD-Positive Advanced Ovarian Cancer Following Front-Line Chemotherapy + Bevacizumab
Sponsor: Peking University Cancer Hospital & Institute • ClinicalTrials.gov ID: NCT06141265
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This study is a multicenter, open-label, single-arm phase II clinical trial investigating the efficacy and safety of niraparib monotherapy maintenance in HRD-positive newly diagnosed advanced epithelial ovarian cancer (EOC), including primary peritoneal and/or fallopian tube tumors, following response to front-line chemotherapy in combination with bevacizumab. A total of 116 patients will be enrolled.
Interventions
-
Niraparib
(Drug)
The starting dose is 300mg or 200mg QD based on the subject's baseline body weight or baseline platelet count
Eligibility criteria
Conditions
Locations
- Peking University Cancer Hospital — Beijing, Beijing Municipality, China
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Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
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