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RECRUITING Not applicable ClinicalTrials.gov

Home-based Rehabilitation Intervention for Phantom Limb Pain in Veterans With Lower Limb Amputations

Sponsor: VA Office of Research and Development • ClinicalTrials.gov ID: NCT06106984

Registry updated: 2026-10-02
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Description

Nearly 60-85% of Veterans with amputations experience pain at the location of the amputated limb called phantom limb pain (PLP). PLP is a major problem and can have a profound impact on Veteran's daily function and ability to fully participate in life. Although several rehabilitation interventions are promising, advances in novel rehabilitation interventions are limited. The objective of this project is to refine a mobile app for graded motor imagery in 12 Veterans with amputations and test the mobile app with 36 Veterans with amputations. For this pilot project, the investigators will measure the preliminary feasibility and acceptability of the intervention. Knowledge from this project will provide evidence to guide future larger studies of this graded motor imagery intervention. Developing novel strategies for chronic pain in this population will positively impact quality of life for Veterans with amputations.

Interventions

  • Graded motor imagery mobile app (Device)
    The Graded Motor Imagery mobile app is a mobile app designed for intervention in phantom limb pain.

Eligibility criteria

Inclusion Criteria: * Must be a military Veteran * \>1 year since unilateral below knee amputation * Moderate or severe (NRS score 4 on a 0-10 scale) PLP * Stable medications over the past 2 weeks * Willing and able to give informed consent * Able to participate in the telehealth study activities with a personal device Exclusion Criteria: * Unstable medical conditions (e.g., uncontrolled diabetes, heart failure exacerbation) * Unstable mental illness or substance use disorder (e.g., active suicidality or psychosis) * Unable to give informed consent due to a cognitive impairment * Fibromyalgia or complex regional pain syndrome-like symptoms

Conditions

Phantom Limb Pain

Locations

  • Minneapolis VA Health Care System, Minneapolis, MN — Minneapolis, Minnesota, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record