RECRUITING Phase 2 / Phase 3 ClinicalTrials.gov

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

Sponsor: National Cancer Institute (NCI) • ClinicalTrials.gov ID: NCT05987241

Registry updated: 2026-10-22

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Description

This phase II/III trial examines whether patients who have undergone surgical removal of bladder, kidney, ureter or urethra, but require an additional treatment called immunotherapy to help prevent their urinary tract (urothelial) cancer from coming back, can be identified by a blood test. Many types of tumors tend to lose cells or release different types of cellular products including their DNA which is referred to as circulating tumor DNA (ctDNA) into the bloodstream before changes can be seen on scans. Health care providers can measure the level of ctDNA in blood or other bodily fluids to determine which patients are at higher risk for disease progression or relapse. In this study, a blood test is used to measure ctDNA and see if there is still cancer somewhere in the body after surgery and if giving a treatment will help eliminate the cancer. Immunotherapy with monoclonal antibodies, such as nivolumab and relatlimab, can help the body's immune system to attack the cancer, and can interfere with the ability of tumor cells to grow and spread. This trial may help doctors determine if ctDNA measurement in blood can better identify patients that need additional treatment, if treatment with nivolumab prolongs patients' life and whether the additional immunotherapy treatment with relatlimab extends time without disease progression or prolongs life of urothelial cancer patients who have undergone surgical removal of their bladder, kidney, ureter or urethra.

Interventions

Biospecimen Collection (Procedure)
Undergo collection of tissue and blood
cfDNA or ctDNA Measurement (Other)
Undergo ctDNA surveillance
Computed Tomography (Procedure)
Undergo CT
Cystoscopy (Procedure)
Undergo cystoscopy
Magnetic Resonance Imaging (Procedure)
Undergo MRI
Nivolumab (Biological)
Given IV
Questionnaire Administration (Other)
Ancillary studies
Relatlimab (Biological)
Given IV

Eligibility criteria

Inclusion Criteria: * PRE-REGISTRATION (STEP 0): Histologically confirmed muscle-invasive urothelial carcinoma of the urethra, bladder, ureter or renal pelvis * PRE-REGISTRATION (STEP 0): Variant histology, including neuroendocrine differentiation, sarcomatoid, micropapillary, glandular, trophoblastic, Mullerian, is allowed if urothelial cancer is predominant histology (any amount of squamous differentiation is allowed provided the tumor is not a pure squamous cell cancer) * PRE-REGISTRATION (STEP 0): Radical surgery (cystectomy with lymph node dissection or nephroureterectomy or ureterectomy) must be ≥ 3 weeks and ≤ 12 weeks (central Signatera pathway) or ≤ 16 weeks (commercial Signatera pathwary) prior to pre-registration. Patients who have had a partial cystectomy as definitive therapy are not eligible * PRE-REGISTRATION (STEP 0): Patients who have had a partial cystectomy as definitive therapy are not eligible * PRE-REGISTRATION (STEP 0): No gross cancer at the surgical margins. Microscopic invasive urothelial carcinoma at the surgical margins (i.e., "positive margins") are allowed. Carcinoma in situ (CIS) at margins is considered negative margins * PRE-REGISTRATION (STEP 0): No evidence of residual cancer or metastasis after radical cystectomy or nephroureterectomy or ureterectomy (imaging is not required prior to pre-registration but is required prior to registration) * PRE-REGISTRATION (STEP 0): Have undergone a radical cystectomy nephroureterectomy, or ureterectomy with pathological evidence of urothelial carcinoma at high risk of recurrence as described in one of the two scenarios below (i or ii). The 7th edition of American Joint Committee on Cancer (AJCC) staging will be utilized.: * (i) Patients who have not received neoadjuvant systemic therapy: pT4N0 or pTanyN+ on radical surgery pathology specimen (i.e., cystectomy, nephroureterectomy, or ureterectomy) and are not eligible for adjuvant cisplatin chemotherapy * (i) Patients ineligible for cisplatin due to at least one of the following criteria and reason for ineligibility should be documented: * (i) Creatinine Clearance (using Cockcroft-Gault): \< 60 mL/min * (i) Common Terminology Criteria for Adverse Events (CTCAE) version 5, grade \>= 2 audiometric hearing loss * (i) CTCAE version 5, grade \>= 2 or above peripheral neuropathy * New York Heart Association Class III heart failure * (i) Eastern Cooperative Oncology Group (ECOG) performance status = 2 * (i) Patients who are eligible for adjuvant cisplatin may be candidates if they refuse adjuvant cisplatin-based chemotherapy, despite being informed by the investigator about the treatment options. The patient's refusal must be documented. * (i) Patients with pT2N0 urothelial cancer on radical surgery specimen (without prior neoadjuvant systemic therapy) with ctDNA(+) Signatera results are eligible only if the result was obtained via commercial testing (central testing is not permitted for this population) (Note: this is distinct from patients with ypT2N0 who are eligible based on ii). * (ii) Patients who received neoadjuvant systemic therapy: ypT2-T4N0 or Nx or ypTanyN+ on radical surgery (i.e., cystectomy. , nephroureterectomy, or ureterectomy) pathology specimen. Neoadjuvant systemic therapy may have included cisplatin-based chemotherapy, cisplatin-based chemotherapy plus PD-1/PD-L1 blockade, or enfortumab vedotin plus PD-1/PD-L1 blockade * PRE-REGISTRATION (STEP 0): Patients are required to meet criteria for one of two criteria: * 1\) Commercial Signatera pathway: * Available commercial Signatera testing result (i.e., ctDNA+ or ctDNA-) from blood sample obtained ≥ 3 weeks and ≤ 16 weeks from time of radical surgery performed as part of standard care * Sites are required to verify that the commercial Signatera report demonstrates a complete 16 target assay design and that the test was designed on exome. This verification is conducted at the site level during the eligibility review. OR * Central Signatera pathway: * Pre-registration samples are to be submitted after pre-registration, at ≥ 3 weeks but ≤ 12 weeks from the time of radical surgery * Ineligible patients for the commercial pathway must use the central Signatera pathway and provide tumor tissue as part of the A032103 study * For patients who have not had neoadjuvant chemotherapy, tumor tissue is preferred from the radical surgery specimen * For patients who have had neoadjuvant therapy, tissue is preferred from the pre-chemotherapy specimen diagnosing muscle-invasive disease (e.g., transurethral resection of bladder tumor specimen) * PRE-REGISTRATION (STEP 0): Age \>= 18 years * PRE-REGISTRATION (STEP 0): ECOG performance status 0-2 * PRE-REGISTRATION (STEP 0): Not pregnant and not nursing, because this study involves an agent that has known genotoxic, mutagenic and teratogenic effects * PRE-REGISTRATION (STEP 0): No postoperative adjuvant systemic therapy after radical surgery * PRE-REGISTRATION (STEP 0): No adjuvant radiation after radical surgery * PRE-REGISTRATION (STEP 0): No treatment with any other type of investigational agent =\< 4 weeks before pre-registration * PRE-REGISTRATION (STEP 0): No previous treatment with LAG-3 blockade therapy * PRE-REGISTRATION (STEP 0): Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial * PRE-REGISTRATION (STEP 0): Absolute neutrophil count (ANC) \>= 1,200/mm\^3 * PRE-REGISTRATION (STEP 0): Platelet count \>= 100,000/mm\^3 * PRE-REGISTRATION (STEP 0): Hemoglobin \>= 8 g/dL * PRE-REGISTRATION (STEP 0): Creatinine =\< 1.5 x upper limit of normal (ULN) or calculated (calc.) creatinine clearance \> 30 mL/min (using either Cockcroft-Gault formula or Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation * PRE-REGISTRATION (STEP 0): Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =\< 3 x ULN * PRE-REGISTRATION (STEP 0): Total bilirubin =\< 1.5 x upper limit of normal (ULN) (except in patients with Gilbert Syndrome, who can have total bilirubin \< 3.0 mg/dL) * PRE-REGISTRATION (STEP 0): For women of childbearing potential only: A negative urine or serum pregnancy test done =\< 14 days prior to pre-registration is required * PRE-REGISTRATION (STEP 0): Not currently requiring hemodialysis * PRE-REGISTRATION (STEP 0): No current or prior history of myocarditis * PRE-REGISTRATION (STEP 0): No history of a grade ≥ 3 immune related adverse event with prior PD-1/PD-L1 blockade in the neoadjuvant setting * PRE-REGISTRATION (STEP 0): No active autoimmune disease or history of autoimmune disease that might recur, which may affect vital organ function or require immune suppressive treatment including systemic corticosteroids. These include but are not limited to patients with a history of immune related neurologic disease, multiple sclerosis, autoimmune (demyelinating) neuropathy, Guillain-Barre syndrome, myasthenia gravis; systemic autoimmune disease such as systemic lupus erythematosus (SLE), connective tissue diseases, scleroderma, inflammatory bowel disease (IBD), Crohn's, ulcerative colitis, hepatitis; and patients with a history of toxic epidermal necrolysis (TEN), Stevens- Johnson syndrome, or phospholipid syndrome because of the risk of recurrence or exacerbation of disease. * PRE-REGISTRATION (STEP 0): Patients with vitiligo, endocrine deficiencies including type I diabetes mellitus, thyroiditis managed with replacement hormones including physiologic corticosteroids are eligible. * PRE-REGISTRATION (STEP 0): Patients with rheumatoid arthritis and other arthropathies, Sjögren's syndrome and psoriasis controlled with topical medication and patients with positive serology, such as antinuclear antibodies (ANA), anti-thyroid antibodies should be evaluated for the presence of target organ involvement and potential need for systemic treatment but should otherwise be eligible. * PRE-REGISTRATION (STEP 0): No current pneumonitis or prior history of non-infectious pneumonitis that required steroids within the previous 5 years. * PRE-REGISTRATION (STEP 0): No known active hepatitis B (e.g., hepatitis B surface antigen \[HBsAg\] reactive) or hepatitis C (e.g., hepatitis C virus \[HCV\] ribonucleic acid \[RNA\] \[qualitative\] is detected). * PRE-REGISTRATION (STEP 0): For patients with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy, if indicated. Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load. * PRE-REGISTRATION (STEP 0): Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible. * PRE-REGISTRATION (STEP 0): No concurrent antineoplastic therapy including anti-hormonal treatments used for cancer therapy (e.g., leuprolide, antiandrogens) * PRE-REGISTRATION (STEP 0): No current immunosuppressive agents (except for corticosteroids as described below). * PRE-REGISTRATION (STEP 0): No condition requiring systemic treatment with either corticosteroids (\> 10 mg daily prednisone equivalents) or other immunosuppressive medications within 14 days of pre-registration (with the exception of steroid pre-medications for contrast allergies). Inhaled or topical steroids and adrenal replacement doses \< 10 mg daily prednisone equivalents are permitted in the absence of active autoimmune disease. * REGISTRATION (STEP 1): Patient must have had radical cystectomy and lymph node dissection or nephroureterectomy or ureterectomy =\< 18 weeks prior to registration. * REGISTRATION (STEP 1): Must have evaluable ctDNA Signatera assay result (i.e., ctDNA+ or ctDNA-) based on either: * Commercial Signatera result OR * Central Signatera testing result (i.e. testing that was performed as part of A032103.) * REGISTRATION (STEP 1): All patients must have confirmed disease-free status defined as no measurable disease by Response Evaluation Criteria in Solid Tumors (RECIST) 1.1, or definitive non-measurable radiographic metastatic disease, within 60 days prior to registration. Patients with equivocal lymph nodes less than 15 mm in short axis, or \< 10 mm in long axis for non-lymph node lesions, not considered by the investigator to represent malignant disease will be eligible. Attempts should be made to resolve the etiology of equivocal lesions with complementary imaging (e.g., PET scan) or biopsy. * REGISTRATION (STEP 1): No major surgery =\< 3 weeks before registration. * REGISTRATION (STEP 1): No live vaccine within 30 days prior to registration. Examples of live vaccines include, but are not limited to, the following: measles, mumps, rubella, varicella/zoster (chicken pox), yellow fever, rabies, Bacillus Calmette- Guerin (BCG), and typhoid vaccine. Seasonal influenza vaccines for injection are generally killed virus vaccines and are allowed; however, intranasal influenza vaccines (e.g., FluMist \[registered trademark\]) are live attenuated vaccines and are not allowed. Coronavirus disease 2019 (COVID-19) vaccines are not live vaccines and are allowed * REGISTRATION (STEP 1): No change since Step 0 pre-registration in clinical condition and/or laboratory tests that would impact the safety of nivolumab +/- relatlimab administration in the opinion of the treating investigator * REGISTRATION (STEP 1): No evidence of high grade urothelial cancer in the bladder for patients with primary urothelial cancers of the upper urinary tract * RE-REGISTRATION (STEP 2) COHORT B, ARM 4 PATIENTS INITIATING NIVOLUMAB AFTER CONVERSION OF ctDNA ASSAY FROM ctDNA(-) to ctDNA (+): * Patient must have converted to ctDNA(+) during serial monitoring performed centrally as part of A032103 * RE-REGISTRATION (STEP 2) COHORT B, ARM 4 PATIENTS INITIATING NIVOLUMAB AFTER CONVERSION OF ctDNA ASSAY FROM ctDNA(-) to ctDNA (+): * No evidence of metastatic disease on the most recent scheduled imaging assessment as outlined in the study calendar (no repeat imaging is necessary specifically at the time of the conversion from ctDNA\[-\] to ctDNA\[+\]). * RE-REGISTRATION (STEP 2) COHORT B, ARM 4 PATIENTS INITIATING NIVOLUMAB AFTER CONVERSION OF ctDNA ASSAY FROM ctDNA(-) to ctDNA (+): * In the opinion of the treating investigator, patient clinical condition and laboratory tests would not impact the safety of nivolumab administration in the opinion of the treating investigator

Conditions

Muscle Invasive Bladder Urothelial Carcinoma Muscle Invasive Renal Pelvis Urothelial Carcinoma Muscle Invasive Ureter Urothelial Carcinoma Muscle Invasive Urethral Urothelial Carcinoma Stage II Bladder Urothelial Carcinoma AJCC v6 and v7 Stage III Bladder Urothelial Carcinoma AJCC v6 and v7 Stage IV Bladder Urothelial Carcinoma AJCC v7

Locations

Cancer Center at Saint Joseph's — Phoenix, Arizona, United States
Mayo Clinic Hospital in Arizona — Phoenix, Arizona, United States
University of Arizona Cancer Center-Orange Grove Campus — Tucson, Arizona, United States
Banner University Medical Center - Tucson — Tucson, Arizona, United States
University of Arizona Cancer Center-North Campus — Tucson, Arizona, United States
Highlands Oncology Group - Fayetteville — Fayetteville, Arkansas, United States
Highlands Oncology Group - Rogers — Rogers, Arkansas, United States
Highlands Oncology Group — Springdale, Arkansas, United States
Kaiser Permanente-Anaheim — Anaheim, California, United States
Kaiser Permanente-Baldwin Park — Baldwin Park, California, United States
Kaiser Permanente-Bellflower — Bellflower, California, United States
Kaiser Permanente Dublin — Dublin, California, United States
Kaiser Permanente-Fontana — Fontana, California, United States
Kaiser Permanente-Fremont — Fremont, California, United States
Kaiser Permanente Fresno Orchard Plaza — Fresno, California, United States
Kaiser Permanente-Fresno — Fresno, California, United States
Kaiser Permanente South Bay — Harbor City, California, United States
Kaiser Permanente-Irvine — Irvine, California, United States
UC San Diego Moores Cancer Center — La Jolla, California, United States
Keck Medicine of USC Koreatown — Los Angeles, California, United States
Kaiser Permanente Los Angeles Medical Center — Los Angeles, California, United States
Los Angeles General Medical Center — Los Angeles, California, United States
USC / Norris Comprehensive Cancer Center — Los Angeles, California, United States
Kaiser Permanente West Los Angeles — Los Angeles, California, United States
UCLA / Jonsson Comprehensive Cancer Center — Los Angeles, California, United States
Kaiser Permanente- Modesto MOB II — Modesto, California, United States
Kaiser Permanente-Modesto — Modesto, California, United States
USC Norris Oncology/Hematology-Newport Beach — Newport Beach, California, United States
Kaiser Permanente-Oakland — Oakland, California, United States
Kaiser Permanente-Ontario — Ontario, California, United States
Stanford Cancer Institute Palo Alto — Palo Alto, California, United States
Kaiser Permanente - Panorama City — Panorama City, California, United States
Kaiser Permanente-Riverside — Riverside, California, United States
Kaiser Permanente-Roseville — Roseville, California, United States
Kaiser Permanente Downtown Commons — Sacramento, California, United States
University of California Davis Comprehensive Cancer Center — Sacramento, California, United States
Kaiser Permanente-South Sacramento — Sacramento, California, United States
Kaiser Permanente-San Diego Zion — San Diego, California, United States
Kaiser Permanente-San Francisco — San Francisco, California, United States
Kaiser Permanente-Santa Teresa-San Jose — San Jose, California, United States
Kaiser Permanente San Leandro — San Leandro, California, United States
Kaiser Permanente-San Marcos — San Marcos, California, United States
Kaiser San Rafael-Gallinas — San Rafael, California, United States
Kaiser Permanente Medical Center - Santa Clara — Santa Clara, California, United States
Saint John's Cancer Institute — Santa Monica, California, United States
Kaiser Permanente-Santa Rosa — Santa Rosa, California, United States
Kaiser Permanente-South San Francisco — South San Francisco, California, United States
Kaiser Permanente-Vallejo — Vallejo, California, United States
Kaiser Permanente-Walnut Creek — Walnut Creek, California, United States
Kaiser Permanente-Woodland Hills — Woodland Hills, California, United States
UCHealth University of Colorado Hospital — Aurora, Colorado, United States
Kaiser Permanente-Franklin — Denver, Colorado, United States
Poudre Valley Hospital — Fort Collins, Colorado, United States
Cancer Care and Hematology-Fort Collins — Fort Collins, Colorado, United States
UCHealth Greeley Hospital — Greeley, Colorado, United States
UCHealth Highlands Ranch Hospital — Highlands Ranch, Colorado, United States
Kaiser Permanente-Rock Creek — Lafayette, Colorado, United States
Kaiser Permanente-Lone Tree — Lone Tree, Colorado, United States
UCHealth Lone Tree Health Center — Lone Tree, Colorado, United States
Medical Center of the Rockies — Loveland, Colorado, United States
Hartford HealthCare - Avon — Avon, Connecticut, United States
Hartford HealthCare - Saint Vincent's Medical Center — Bridgeport, Connecticut, United States
Smilow Cancer Hospital-Derby Care Center — Derby, Connecticut, United States
Hartford Healthcare - Fairfield — Fairfield, Connecticut, United States
Smilow Cancer Hospital Care Center-Fairfield — Fairfield, Connecticut, United States
Smilow Cancer Hospital Care Center at Glastonbury — Glastonbury, Connecticut, United States
Smilow Cancer Hospital Care Center at Greenwich — Greenwich, Connecticut, United States
Smilow Cancer Hospital Care Center - Guilford — Guilford, Connecticut, United States
Hartford Hospital — Hartford, Connecticut, United States
Smilow Cancer Hospital Care Center at Saint Francis — Hartford, Connecticut, United States
Hartford HealthCare - Manchester — Manchester, Connecticut, United States
Midstate Medical Center — Meriden, Connecticut, United States
The Hospital of Central Connecticut — New Britain, Connecticut, United States
Yale University — New Haven, Connecticut, United States
Yale-New Haven Hospital North Haven Medical Center — North Haven, Connecticut, United States
Smilow Cancer Hospital Care Center at Long Ridge — Stamford, Connecticut, United States
Smilow Cancer Hospital-Torrington Care Center — Torrington, Connecticut, United States
Smilow Cancer Hospital Care Center-Trumbull — Trumbull, Connecticut, United States
Smilow Cancer Hospital-Waterbury Care Center — Waterbury, Connecticut, United States
Smilow Cancer Hospital Care Center - Waterford — Waterford, Connecticut, United States
Helen F Graham Cancer Center — Newark, Delaware, United States
Medical Oncology Hematology Consultants PA — Newark, Delaware, United States
MedStar Georgetown University Hospital — Washington D.C., District of Columbia, United States
MedStar Washington Hospital Center — Washington D.C., District of Columbia, United States
Sibley Memorial Hospital — Washington D.C., District of Columbia, United States
George Washington University Medical Center — Washington D.C., District of Columbia, United States
Mount Sinai Comprehensive Cancer Center at Aventura — Aventura, Florida, United States
UM Sylvester Comprehensive Cancer Center at Aventura — Aventura, Florida, United States
UM Sylvester Comprehensive Cancer Center at Coral Gables — Coral Gables, Florida, United States
UM Sylvester Comprehensive Cancer Center at Deerfield Beach — Deerfield Beach, Florida, United States
Malcom Randall Veterans Administration Medical Center — Gainesville, Florida, United States
UF Health Cancer Institute - Gainesville — Gainesville, Florida, United States
Memorial Regional Hospital/Joe DiMaggio Children's Hospital — Hollywood, Florida, United States
Mayo Clinic in Florida — Jacksonville, Florida, United States
University of Miami Miller School of Medicine-Sylvester Cancer Center — Miami, Florida, United States
Miami Cancer Institute — Miami, Florida, United States
UM Sylvester Comprehensive Cancer Center at Kendall — Miami, Florida, United States
Mount Sinai Medical Center — Miami Beach, Florida, United States
University of Miami Sylvester Comprehensive Cancer Center at Sole Mia — North Miami, Florida, United States
AdventHealth Orlando — Orlando, Florida, United States
Memorial Hospital West — Pembroke Pines, Florida, United States
UM Sylvester Comprehensive Cancer Center at Plantation — Plantation, Florida, United States
Grady Health System — Atlanta, Georgia, United States
Emory University Hospital Midtown — Atlanta, Georgia, United States
Emory University Hospital/Winship Cancer Institute — Atlanta, Georgia, United States
Emory Saint Joseph's Hospital — Atlanta, Georgia, United States
Northside Hospital — Atlanta, Georgia, United States
Northside Hospital - Duluth — Duluth, Georgia, United States
Emory Johns Creek Hospital — Johns Creek, Georgia, United States
Northside Hospital - Gwinnett — Lawrenceville, Georgia, United States
Kaiser Permanente Moanalua Medical Center — Honolulu, Hawaii, United States
Saint Alphonsus Cancer Care Center-Boise — Boise, Idaho, United States
Saint Alphonsus Cancer Care Center-Caldwell — Caldwell, Idaho, United States
Kootenai Health - Coeur d'Alene — Coeur d'Alene, Idaho, United States
Saint Alphonsus Cancer Care Center-Nampa — Nampa, Idaho, United States
Kootenai Clinic Cancer Services - Post Falls — Post Falls, Idaho, United States
Kootenai Clinic Cancer Services - Sandpoint — Sandpoint, Idaho, United States
Advocate Good Shepherd Hospital — Barrington, Illinois, United States
Illinois CancerCare-Bloomington — Bloomington, Illinois, United States
Illinois CancerCare-Canton — Canton, Illinois, United States
Illinois CancerCare-Carthage — Carthage, Illinois, United States
Northwestern University — Chicago, Illinois, United States
University of Illinois — Chicago, Illinois, United States
Swedish Covenant Hospital — Chicago, Illinois, United States
University of Chicago Comprehensive Cancer Center — Chicago, Illinois, United States
Advocate Illinois Masonic Medical Center — Chicago, Illinois, United States
AMG Crystal Lake - Oncology — Crystal Lake, Illinois, United States
Carle at The Riverfront — Danville, Illinois, United States
Cancer Care Specialists of Illinois - Decatur — Decatur, Illinois, United States
Decatur Memorial Hospital — Decatur, Illinois, United States
Northwestern Medicine Cancer Center Kishwaukee — DeKalb, Illinois, United States
Illinois CancerCare-Dixon — Dixon, Illinois, United States
Advocate Good Samaritan Hospital — Downers Grove, Illinois, United States
Carle Physician Group-Effingham — Effingham, Illinois, United States
Crossroads Cancer Center — Effingham, Illinois, United States
Advocate Sherman Hospital — Elgin, Illinois, United States
Elmhurst Memorial Hospital — Elmhurst, Illinois, United States
Illinois CancerCare-Eureka — Eureka, Illinois, United States
NorthShore University HealthSystem-Evanston Hospital — Evanston, Illinois, United States
Illinois CancerCare-Galesburg — Galesburg, Illinois, United States
Northwestern Medicine Cancer Center Delnor — Geneva, Illinois, United States
NorthShore University HealthSystem-Glenbrook Hospital — Glenview, Illinois, United States
Northwestern Medicine Glenview Outpatient Center — Glenview, Illinois, United States
Northwestern Medicine Grayslake Outpatient Center — Grayslake, Illinois, United States
Ingalls Memorial Hospital — Harvey, Illinois, United States
Advocate South Suburban Hospital — Hazel Crest, Illinois, United States
NorthShore University HealthSystem-Highland Park Hospital — Highland Park, Illinois, United States
Illinois CancerCare-Kewanee Clinic — Kewanee, Illinois, United States
Northwestern Medicine Lake Forest Hospital — Lake Forest, Illinois, United States
AMG Libertyville - Oncology — Libertyville, Illinois, United States
Condell Memorial Hospital — Libertyville, Illinois, United States
Illinois CancerCare-Macomb — Macomb, Illinois, United States
Carle Physician Group-Mattoon/Charleston — Mattoon, Illinois, United States
Edward Hospital/Cancer Center — Naperville, Illinois, United States
UC Comprehensive Cancer Center at Silver Cross — New Lenox, Illinois, United States
Cancer Care Center of O'Fallon — O'Fallon, Illinois, United States
Northwestern Medicine Oak Brook — Oak Brook, Illinois, United States
Advocate Christ Medical Center — Oak Lawn, Illinois, United States
Northwestern Medicine Orland Park — Orland Park, Illinois, United States
University of Chicago Medicine-Orland Park — Orland Park, Illinois, United States
Illinois CancerCare-Ottawa Clinic — Ottawa, Illinois, United States
Advocate Lutheran General Hospital — Park Ridge, Illinois, United States
Illinois CancerCare-Pekin — Pekin, Illinois, United States
Illinois CancerCare-Peoria — Peoria, Illinois, United States
Illinois CancerCare-Peru — Peru, Illinois, United States
Edward Hospital/Cancer Center?Plainfield — Plainfield, Illinois, United States
Illinois CancerCare-Princeton — Princeton, Illinois, United States
UW Health Carbone Cancer Center Rockford — Rockford, Illinois, United States
Memorial Hospital East — Shiloh, Illinois, United States
Southern Illinois University School of Medicine — Springfield, Illinois, United States
Springfield Clinic — Springfield, Illinois, United States
Springfield Memorial Hospital — Springfield, Illinois, United States
Carle Cancer Center — Urbana, Illinois, United States
Northwestern Medicine Cancer Center Warrenville — Warrenville, Illinois, United States
Illinois CancerCare - Washington — Washington, Illinois, United States
UChicago Medicine Northwest Indiana — Crown Point, Indiana, United States
Indiana University/Melvin and Bren Simon Cancer Center — Indianapolis, Indiana, United States
Mary Greeley Medical Center — Ames, Iowa, United States
McFarland Clinic - Ames — Ames, Iowa, United States
UI Health Care Mission Cancer and Blood - Ankeny Clinic — Ankeny, Iowa, United States
University of Iowa Healthcare Cancer Services Quad Cities — Bettendorf, Iowa, United States
McFarland Clinic - Boone — Boone, Iowa, United States
UI Health Care Mission Cancer and Blood - West Des Moines Clinic — Clive, Iowa, United States
Iowa Methodist Medical Center — Des Moines, Iowa, United States
UI Health Care Mission Cancer and Blood - Des Moines Clinic — Des Moines, Iowa, United States
Mercy Medical Center - Des Moines — Des Moines, Iowa, United States
UI Health Care Mission Cancer and Blood - Laurel Clinic — Des Moines, Iowa, United States
McFarland Clinic - Trinity Cancer Center — Fort Dodge, Iowa, United States
University of Iowa/Holden Comprehensive Cancer Center — Iowa City, Iowa, United States
McFarland Clinic - Jefferson — Jefferson, Iowa, United States
McFarland Clinic - Marshalltown — Marshalltown, Iowa, United States
UI Health Care Mission Cancer and Blood - Waukee Clinic — Waukee, Iowa, United States
HaysMed — Hays, Kansas, United States
University of Kansas Cancer Center — Kansas City, Kansas, United States
Lawrence Memorial Hospital — Lawrence, Kansas, United States
The University of Kansas Cancer Center - Olathe — Olathe, Kansas, United States
University of Kansas Cancer Center-Overland Park — Overland Park, Kansas, United States
Salina Regional Health Center — Salina, Kansas, United States
University of Kansas Health System Saint Francis Campus — Topeka, Kansas, United States
University of Kansas Hospital-Westwood Cancer Center — Westwood, Kansas, United States
University of Kentucky/Markey Cancer Center — Lexington, Kentucky, United States
The James Graham Brown Cancer Center at University of Louisville — Louisville, Kentucky, United States
Baptist Health Louisville — Louisville, Kentucky, United States
UofL Health Medical Center Northeast — Louisville, Kentucky, United States
Louisiana Hematology Oncology Associates LLC — Baton Rouge, Louisiana, United States
Mary Bird Perkins Cancer Center - Metairie — Metairie, Louisiana, United States
Ochsner Medical Center Jefferson — New Orleans, Louisiana, United States
Lafayette Family Cancer Center-EMMC — Brewer, Maine, United States
University of Maryland/Greenebaum Cancer Center — Baltimore, Maryland, United States
Johns Hopkins University/Sidney Kimmel Cancer Center — Baltimore, Maryland, United States
UPMC Western Maryland — Cumberland, Maryland, United States
FMH James M Stockman Cancer Institute — Frederick, Maryland, United States
Beverly Hospital — Beverly, Massachusetts, United States
Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
Dana-Farber Cancer Institute — Boston, Massachusetts, United States
Dana-Farber Cancer Institute at Boston Medical Center - Brighton — Brighton, Massachusetts, United States
Lahey Clinic — Burlington, Massachusetts, United States
Dana-Farber Cancer Institute at Foxborough — Foxborough, Massachusetts, United States
Addison Gilbert Hospital — Gloucester, Massachusetts, United States
Dana-Farber/Brigham and Women's Cancer Center at Milford Regional — Milford, Massachusetts, United States
Lahey Clinic Peabody — Peabody, Massachusetts, United States
Dana-Farber/Brigham and Women's Cancer Center at South Shore — South Weymouth, Massachusetts, United States
Beth Israel Deaconess Medical Center/Winchester Center for Cancer Care — Winchester, Massachusetts, United States
Trinity Health Saint Joseph Mercy Hospital Ann Arbor — Ann Arbor, Michigan, United States
University of Michigan Rogel Cancer Center — Ann Arbor, Michigan, United States
Bronson Battle Creek — Battle Creek, Michigan, United States
McLaren Cancer Institute-Bay City — Bay City, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology - Brighton — Brighton, Michigan, United States
University of Michigan - Brighton Center for Specialty Care — Brighton, Michigan, United States
Henry Ford Cancer Institute-Downriver — Brownstown, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology - Canton — Canton, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital — Chelsea, Michigan, United States
Henry Ford Macomb Hospital-Clinton Township — Clinton Township, Michigan, United States
Henry Ford Medical Center-Fairlane — Dearborn, Michigan, United States
Wayne State University/Karmanos Cancer Institute — Detroit, Michigan, United States
Henry Ford Hospital — Detroit, Michigan, United States
OSF Saint Francis Hospital and Medical Group — Escanaba, Michigan, United States
Weisberg Cancer Treatment Center — Farmington Hills, Michigan, United States
Cancer Hematology Centers - Flint — Flint, Michigan, United States
Genesee Hematology Oncology PC — Flint, Michigan, United States
Genesys Hurley Cancer Institute — Flint, Michigan, United States
Hurley Medical Center — Flint, Michigan, United States
Corewell Health Grand Rapids Hospitals - Butterworth Hospital — Grand Rapids, Michigan, United States
Trinity Health Grand Rapids Hospital — Grand Rapids, Michigan, United States
Allegiance Health — Jackson, Michigan, United States
Bronson Methodist Hospital — Kalamazoo, Michigan, United States
West Michigan Cancer Center — Kalamazoo, Michigan, United States
Karmanos Cancer Institute at McLaren Greater Lansing — Lansing, Michigan, United States
University of Michigan Health - Sparrow Lansing — Lansing, Michigan, United States
Trinity Health Saint Mary Mercy Livonia Hospital — Livonia, Michigan, United States
Trinity Health Muskegon Hospital — Muskegon, Michigan, United States
Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan, United States
Cancer and Hematology Centers of Western Michigan - Norton Shores — Norton Shores, Michigan, United States
Henry Ford Medical Center-Columbus — Novi, Michigan, United States
McLaren Cancer Institute-Northern Michigan — Petoskey, Michigan, United States
Trinity Health Saint Joseph Mercy Oakland Hospital — Pontiac, Michigan, United States
Corewell Health Reed City Hospital — Reed City, Michigan, United States
MyMichigan Medical Center Saginaw — Saginaw, Michigan, United States
Oncology Hematology Associates of Saginaw Valley PC — Saginaw, Michigan, United States
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center — Saint Joseph, Michigan, United States
Corewell Health Lakeland Hospitals - Saint Joseph Hospital — Saint Joseph, Michigan, United States
MyMichigan Medical Center Tawas — Tawas City, Michigan, United States
Munson Medical Center — Traverse City, Michigan, United States
Henry Ford West Bloomfield Hospital — West Bloomfield, Michigan, United States
Saint Mary's Oncology/Hematology Associates of West Branch — West Branch, Michigan, United States
Henry Ford Wyandotte Hospital — Wyandotte, Michigan, United States
University of Michigan Health - West — Wyoming, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus — Ypsilanti, Michigan, United States
Sanford Joe Lueken Cancer Center — Bemidji, Minnesota, United States
Mercy Hospital — Coon Rapids, Minnesota, United States
Fairview Southdale Hospital — Edina, Minnesota, United States
Abbott-Northwestern Hospital — Minneapolis, Minnesota, United States
Hennepin County Medical Center — Minneapolis, Minnesota, United States
Coborn Cancer Center at Saint Cloud Hospital — Saint Cloud, Minnesota, United States
Park Nicollet Clinic - Saint Louis Park — Saint Louis Park, Minnesota, United States
Regions Hospital — Saint Paul, Minnesota, United States
United Hospital — Saint Paul, Minnesota, United States
University of Mississippi Medical Center — Jackson, Mississippi, United States
Mercy Oncology and Hematology - Clayton-Clarkson — Ballwin, Missouri, United States
Saint Francis Medical Center — Cape Girardeau, Missouri, United States
Siteman Cancer Center at Saint Peters Hospital — City of Saint Peters, Missouri, United States
MU Health - University Hospital/Ellis Fischel Cancer Center — Columbia, Missouri, United States
Siteman Cancer Center at West County Hospital — Creve Coeur, Missouri, United States
Parkland Health Center - Farmington — Farmington, Missouri, United States
MU Health Care Goldschmidt Cancer Center — Jefferson City, Missouri, United States
University Health Truman Medical Center — Kansas City, Missouri, United States
University of Kansas Cancer Center - Briarcliff — Kansas City, Missouri, United States
Kansas City Veterans Affairs Medical Center — Kansas City, Missouri, United States
University of Kansas Cancer Center - North — Kansas City, Missouri, United States
University of Kansas Cancer Center - Lee's Summit — Lee's Summit, Missouri, United States
University of Kansas Cancer Center at North Kansas City Hospital — North Kansas City, Missouri, United States
Sainte Genevieve County Memorial Hospital — Sainte Genevieve, Missouri, United States
Mercy Hospital Springfield — Springfield, Missouri, United States
Washington University School of Medicine — St Louis, Missouri, United States
Veteran's Affairs Medical Center - Saint Louis — St Louis, Missouri, United States
Mercy Hospital South — St Louis, Missouri, United States
Siteman Cancer Center-South County — St Louis, Missouri, United States
Missouri Baptist Medical Center — St Louis, Missouri, United States
Siteman Cancer Center at Christian Hospital — St Louis, Missouri, United States
Mercy Hospital Saint Louis — St Louis, Missouri, United States
Missouri Baptist Sullivan Hospital — Sullivan, Missouri, United States
Community Hospital of Anaconda — Anaconda, Montana, United States
Billings Clinic Cancer Center — Billings, Montana, United States
Bozeman Health Deaconess Hospital — Bozeman, Montana, United States
Benefis Sletten Cancer Institute — Great Falls, Montana, United States
Logan Health Medical Center — Kalispell, Montana, United States
Community Medical Center — Missoula, Montana, United States
Nebraska Medicine-Bellevue — Bellevue, Nebraska, United States
Nebraska Medicine-Village Pointe — Omaha, Nebraska, United States
University of Nebraska Medical Center — Omaha, Nebraska, United States
OptumCare Cancer Care at Charleston — Las Vegas, Nevada, United States
OptumCare Cancer Care at Fort Apache — Las Vegas, Nevada, United States
New Hampshire Oncology Hematology PA-Concord — Concord, New Hampshire, United States
Solinsky Center for Cancer Care — Manchester, New Hampshire, United States
Memorial Sloan Kettering Basking Ridge — Basking Ridge, New Jersey, United States
Jefferson Cherry Hill Hospital — Cherry Hill, New Jersey, United States
Hackensack University Medical Center — Hackensack, New Jersey, United States
Jersey City Medical Center — Jersey City, New Jersey, United States
Monmouth Medical Center Southern Campus — Lakewood, New Jersey, United States
Cooperman Barnabas Medical Center — Livingston, New Jersey, United States
Monmouth Medical Center — Long Branch, New Jersey, United States
Southern Ocean County Medical Center — Manahawkin, New Jersey, United States
Memorial Sloan Kettering Monmouth — Middletown, New Jersey, United States
Memorial Sloan Kettering Bergen — Montvale, New Jersey, United States
Rutgers Cancer Institute of New Jersey — New Brunswick, New Jersey, United States
Sidney Kimmel Cancer Center Washington Township — Sewell, New Jersey, United States
Robert Wood Johnson University Hospital Somerset — Somerville, New Jersey, United States
Community Medical Center — Toms River, New Jersey, United States
University of New Mexico Cancer Center — Albuquerque, New Mexico, United States
Presbyterian Kaseman Hospital — Albuquerque, New Mexico, United States
Presbyterian Rust Medical Center/Jorgensen Cancer Center — Rio Rancho, New Mexico, United States
Maimonides Medical Center — Brooklyn, New York, United States
Roswell Park Cancer Institute — Buffalo, New York, United States
Memorial Sloan Kettering Commack — Commack, New York, United States
The New York Hospital Medical Center of Queens — Flushing, New York, United States
Glens Falls Hospital — Glens Falls, New York, United States
Memorial Sloan Kettering Westchester — Harrison, New York, United States
NYU Langone Hospital - Long Island — Mineola, New York, United States
Mount Sinai Chelsea — New York, New York, United States
Laura and Isaac Perlmutter Cancer Center at NYU Langone — New York, New York, United States
Mount Sinai Hospital — New York, New York, United States
Memorial Sloan Kettering Cancer Center — New York, New York, United States
NYP/Weill Cornell Medical Center — New York, New York, United States
Rochester General Hospital — Rochester, New York, United States
Unity Park Ridge Campus — Rochester, New York, United States
University of Rochester — Rochester, New York, United States
Stony Brook University Medical Center — Stony Brook, New York, United States
Montefiore Medical Center-Einstein Campus — The Bronx, New York, United States
Memorial Sloan Kettering Nassau — Uniondale, New York, United States
Wilmot Cancer Institute at Webster — Webster, New York, United States
Atrium Health Stanly/LCI-Albemarle — Albemarle, North Carolina, United States
Duke Cancer Center Cary — Cary, North Carolina, United States
UNC Lineberger Comprehensive Cancer Center — Chapel Hill, North Carolina, United States
Carolinas Medical Center/Levine Cancer Institute — Charlotte, North Carolina, United States
Atrium Health Pineville/LCI-Pineville — Charlotte, North Carolina, United States
Levine Cancer Institute-SouthPark — Charlotte, North Carolina, United States
Atrium Health University City/LCI-University — Charlotte, North Carolina, United States
Levine Cancer Institute-Ballantyne — Charlotte, North Carolina, United States
Wake Forest University at Clemmons — Clemmons, North Carolina, United States
Atrium Health Cabarrus/LCI-Concord — Concord, North Carolina, United States
Duke University Medical Center — Durham, North Carolina, United States
Duke Cancer Center Southpoint — Durham, North Carolina, United States
Levine Cancer Institute - Rutherford — Forest City, North Carolina, United States
Levine Cancer Institute-Gaston — Gastonia, North Carolina, United States
Levine Cancer Institute - Huntersville — Huntersville, North Carolina, United States
Atrium Health Lincoln/LCI-Lincolnton — Lincolnton, North Carolina, United States
Levine Cancer Institute - Union West — Matthews, North Carolina, United States
Atrium Health Union/LCI-Union — Monroe, North Carolina, United States
FirstHealth of the Carolinas-Moore Regional Hospital — Pinehurst, North Carolina, United States
Duke Cancer Center Raleigh — Raleigh, North Carolina, United States
Atrium Health Cleveland/LCI-Cleveland — Shelby, North Carolina, United States
Wake Forest University Health Sciences — Winston-Salem, North Carolina, United States
Sanford Bismarck Medical Center — Bismarck, North Dakota, United States
Sanford Broadway Medical Center — Fargo, North Dakota, United States
Sanford Roger Maris Cancer Center — Fargo, North Dakota, United States
OhioHealth O'Bleness Hospital — Athens, Ohio, United States
University of Cincinnati Cancer Center-UC Medical Center — Cincinnati, Ohio, United States
Ohio State University Comprehensive Cancer Center — Columbus, Ohio, United States
Columbus Oncology and Hematology Associates Inc — Columbus, Ohio, United States
Riverside Methodist Hospital — Columbus, Ohio, United States
Grant Medical Center — Columbus, Ohio, United States
Doctors Hospital — Columbus, Ohio, United States
Delaware Health Center-Grady Cancer Center — Delaware, Ohio, United States
Grady Memorial Hospital — Delaware, Ohio, United States
Columbus Oncology and Hematology Associates — Dublin, Ohio, United States
Dublin Methodist Hospital — Dublin, Ohio, United States
OhioHealth Mansfield Hospital — Mansfield, Ohio, United States
OhioHealth Marion General Hospital — Marion, Ohio, United States
OhioHealth Pickerington Methodist Hospital — Pickerington, Ohio, United States
ProMedica Flower Hospital — Sylvania, Ohio, United States
University of Cincinnati Cancer Center-West Chester — West Chester, Ohio, United States
OhioHealth Westerville Medical Campus/Westerville Cancer Center — Westerville, Ohio, United States
Cancer Centers of Southwest Oklahoma Research — Lawton, Oklahoma, United States
University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma, United States
Oklahoma Cancer Specialists and Research Institute-Tulsa — Tulsa, Oklahoma, United States
Saint Alphonsus Cancer Care Center-Ontario — Ontario, Oregon, United States
Providence Willamette Falls Medical Center — Oregon City, Oregon, United States
Providence Portland Medical Center — Portland, Oregon, United States
Providence Saint Vincent Medical Center — Portland, Oregon, United States
Oregon Health and Science University — Portland, Oregon, United States
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania, United States
UPMC Altoona — Altoona, Pennsylvania, United States
UPMC-Heritage Valley Health System Beaver — Beaver, Pennsylvania, United States
Lehigh Valley Hospital - Muhlenberg — Bethlehem, Pennsylvania, United States
Pocono Medical Center — East Stroudsburg, Pennsylvania, United States
UPMC Hillman Cancer Center Erie — Erie, Pennsylvania, United States
UPMC Cancer Centers - Arnold Palmer Pavilion — Greensburg, Pennsylvania, United States
UPMC Pinnacle Cancer Center/Community Osteopathic Campus — Harrisburg, Pennsylvania, United States
Lancaster General Ann B Barshinger Cancer Institute — Lancaster, Pennsylvania, United States
UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion — Mechanicsburg, Pennsylvania, United States
UPMC Hillman Cancer Center - Monroeville — Monroeville, Pennsylvania, United States
University of Pennsylvania/Abramson Cancer Center — Philadelphia, Pennsylvania, United States
Thomas Jefferson University Hospital — Philadelphia, Pennsylvania, United States
Jefferson Torresdale Hospital — Philadelphia, Pennsylvania, United States
UPMC-Saint Margaret — Pittsburgh, Pennsylvania, United States
UPMC Hillman Cancer Center — Pittsburgh, Pennsylvania, United States
UPMC-Passavant Hospital — Pittsburgh, Pennsylvania, United States
UPMC-Saint Clair Hospital Cancer Center — Pittsburgh, Pennsylvania, United States
Reading Hospital — West Reading, Pennsylvania, United States
Asplundh Cancer Pavilion — Willow Grove, Pennsylvania, United States
Smilow Cancer Hospital Care Center - Westerly — Westerly, Rhode Island, United States
AnMed Health Cancer Center — Anderson, South Carolina, United States
Prisma Health Cancer Institute - Spartanburg — Boiling Springs, South Carolina, United States
Medical University of South Carolina — Charleston, South Carolina, United States
Prisma Health Cancer Institute - Easley — Easley, South Carolina, United States
Gibbs Cancer Center-Gaffney — Gaffney, South Carolina, United States
Prisma Health Cancer Institute - Butternut — Greenville, South Carolina, United States
Prisma Health Cancer Institute - Faris — Greenville, South Carolina, United States
Prisma Health Greenville Memorial Hospital — Greenville, South Carolina, United States
Prisma Health Cancer Institute - Eastside — Greenville, South Carolina, United States
Prisma Health Cancer Institute - Greer — Greer, South Carolina, United States
Gibbs Cancer Center-Pelham — Greer, South Carolina, United States
Levine Cancer Institute-Rock Hill — Rock Hill, South Carolina, United States
Prisma Health Cancer Institute - Seneca — Seneca, South Carolina, United States
Spartanburg Medical Center — Spartanburg, South Carolina, United States
SMC Center for Hematology Oncology Union — Union, South Carolina, United States
Sanford Cancer Center Oncology Clinic — Sioux Falls, South Dakota, United States
Sanford USD Medical Center - Sioux Falls — Sioux Falls, South Dakota, United States
The West Clinic - Wolf River — Germantown, Tennessee, United States
Vanderbilt University/Ingram Cancer Center — Nashville, Tennessee, United States
UT Southwestern Simmons Cancer Center - RedBird — Dallas, Texas, United States
UT Southwestern/Simmons Cancer Center-Dallas — Dallas, Texas, United States
UT Southwestern/Simmons Cancer Center-Fort Worth — Fort Worth, Texas, United States
Lyndon Baines Johnson General Hospital — Houston, Texas, United States
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center — Houston, Texas, United States
Ben Taub General Hospital — Houston, Texas, United States
Michael E DeBakey VA Medical Center — Houston, Texas, United States
UT Southwestern Clinical Center at Richardson/Plano — Richardson, Texas, United States
Huntsman Cancer Institute/University of Utah — Salt Lake City, Utah, United States
Central Vermont Medical Center/National Life Cancer Treatment — Berlin Corners, Vermont, United States
University of Vermont Medical Center — Burlington, Vermont, United States
University of Vermont and State Agricultural College — Burlington, Vermont, United States
University of Virginia Cancer Center — Charlottesville, Virginia, United States
Bon Secours Memorial Regional Medical Center — Mechanicsville, Virginia, United States
Bon Secours Saint Francis Medical Center — Midlothian, Virginia, United States
Bon Secours Richmond Community Hospital — Richmond, Virginia, United States
Bon Secours Saint Mary's Hospital — Richmond, Virginia, United States
VCU Massey Cancer Center at Stony Point — Richmond, Virginia, United States
VCU Massey Comprehensive Cancer Center — Richmond, Virginia, United States
VCU Community Memorial Health Center — South Hill, Virginia, United States
Virginia Mason Medical Center — Seattle, Washington, United States
Vandalia Health/CAMC Institute for Academic Medicine — Charleston, West Virginia, United States
West Virginia University Healthcare — Morgantown, West Virginia, United States
ThedaCare Regional Cancer Center — Appleton, Wisconsin, United States
Aurora Saint Luke's South Shore — Cudahy, Wisconsin, United States
Marshfield Medical Center-EC Cancer Center — Eau Claire, Wisconsin, United States
Aurora Cancer Care-Grafton — Grafton, Wisconsin, United States
Saint Vincent Hospital Cancer Center Green Bay — Green Bay, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Saint Mary's — Green Bay, Wisconsin, United States
Aurora BayCare Medical Center — Green Bay, Wisconsin, United States
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center — Madison, Wisconsin, United States
University of Wisconsin Carbone Cancer Center - University Hospital — Madison, Wisconsin, United States
Aurora Bay Area Medical Group-Marinette — Marinette, Wisconsin, United States
Marshfield Medical Center-Marshfield — Marshfield, Wisconsin, United States
Aurora Saint Luke's Medical Center — Milwaukee, Wisconsin, United States
Medical College of Wisconsin — Milwaukee, Wisconsin, United States
Aurora Sinai Medical Center — Milwaukee, Wisconsin, United States
ProHealth D N Greenwald Center — Mukwonago, Wisconsin, United States
ProHealth Oconomowoc Memorial Hospital — Oconomowoc, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Oconto Falls — Oconto Falls, Wisconsin, United States
Vince Lombardi Cancer Clinic - Oshkosh — Oshkosh, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Sheboygan — Sheboygan, Wisconsin, United States
Vince Lombardi Cancer Clinic-Sheboygan — Sheboygan, Wisconsin, United States
Marshfield Medical Center-River Region at Stevens Point — Stevens Point, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Sturgeon Bay — Sturgeon Bay, Wisconsin, United States
Aurora Medical Center in Summit — Summit, Wisconsin, United States
Vince Lombardi Cancer Clinic-Two Rivers — Two Rivers, Wisconsin, United States
ProHealth Waukesha Memorial Hospital — Waukesha, Wisconsin, United States
UW Cancer Center at ProHealth Care — Waukesha, Wisconsin, United States
Aurora Cancer Care-Milwaukee West — Wauwatosa, Wisconsin, United States
Aurora West Allis Medical Center — West Allis, Wisconsin, United States
Marshfield Medical Center - Weston — Weston, Wisconsin, United States
Arthur J E Child Comprehensive Cancer Centre — Calgary, Alberta, Canada
Cross Cancer Institute — Edmonton, Alberta, Canada
BCCA-Vancouver Cancer Centre — Vancouver, British Columbia, Canada
Waterloo Regional Health Network — Kitchener, Ontario, Canada
London Regional Cancer Program — London, Ontario, Canada
Ottawa Hospital and Cancer Center-General Campus — Ottawa, Ontario, Canada
Odette Cancer Centre- Sunnybrook Health Sciences Centre — Toronto, Ontario, Canada
University Health Network-Princess Margaret Hospital — Toronto, Ontario, Canada
Allan Blair Cancer Centre — Regina, Saskatchewan, Canada
Saskatoon Cancer Centre — Saskatoon, Saskatchewan, Canada

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