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RECRUITING Phase 4 ClinicalTrials.gov

QL Block in Laparoscopic Myomectomy

Sponsor: Joseph Findley MD • ClinicalTrials.gov ID: NCT05979493

Registry updated: 2026-09-11
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Description

This study aims to determine the efficacy of a quadratus lumborum (QL) block in decreasing postoperative pain in patients undergoing myomectomy for uterine fibroids. A QL block is a temporary anesthetic injection in the quadratus lumborum muscle, a muscle in the lower back, that has been previously shown to significantly reduce postoperative pain levels in patients undergoing abdominal and pelvic surgery. Because of its demonstrated effects, the QL block is becoming a standard of anesthesia and surgical care. Since participants will be undergoing a myomectomy procedure, the investigators believe that participants may qualify to participate in this study. The investigators will be comparing patients who receive the QL block (in addition to standard anesthesia and postoperative pain care) with patients who do not receive the QL block (in addition to standard care). The participants will be randomly assigned to one of the two groups and may or may not actually receive the block.

Interventions

  • Bupivacain (Drug)
    30cc IM injection in each quadratus lumborum muscle (60cc total).
  • Saline (Drug)
    30cc IM injection in each quadratus lumborum muscle (60cc total).

Eligibility criteria

Inclusion Criteria: * Presence of uterine fibroids requiring surgical excision with preservation of the uterus * Stated willingness to comply with all study procedures and availability for the duration of the study * Provision of signed and dated informed consent form Exclusion Criteria: * Pre-existing diagnoses of anxiety or depression * Pre-existing coagulopathies * Pre-existing neuropathic or chronic pelvic pain * Chronic opioid use * Illiteracy due to inability to read and understand plain questionnaire * Non-English speaking * BMI \>38

Conditions

Postoperative Pain Fibroid Uterus

Locations

  • University Hospitals Ahuja Medical Center — Beachwood, Ohio, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record