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RECRUITING Phase 3 ClinicalTrials.gov

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

Sponsor: NRG Oncology • ClinicalTrials.gov ID: NCT05946213

Registry updated: 2026-09-10
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Description

This phase III trial compares stereotactic body radiation therapy (SBRT), (five treatments over two weeks using a higher dose per treatment) to usual radiation therapy (20 to 45 treatments over 4 to 9 weeks) for the treatment of high-risk prostate cancer. SBRT uses special equipment to position a patient and deliver radiation to tumors with high precision. This method may kill tumor cells with fewer doses over a shorter period of time. This trial is evaluating if shorter duration radiation prevents cancer from coming back as well as the usual radiation treatment.

Interventions

  • Biospecimen Collection (Procedure)
    Undergo blood and urine sample collection
  • Bone Scan (Procedure)
    Undergo bone scan
  • Computed Tomography (Procedure)
    Undergo CT or PET/CT
  • External Beam Radiation Therapy (Radiation)
    Undergo EBRT
  • Magnetic Resonance Imaging (Procedure)
    Undergo MRI
  • Positron Emission Tomography (Procedure)
    Undergo PET/CT
  • Quality-of-Life Assessment (Other)
    Ancillary studies
  • Questionnaire Administration (Other)
    Ancillary studies
  • Stereotactic Body Radiation Therapy (Radiation)
    Undergo SBRT

Eligibility criteria

Inclusion Criteria: * Pathologically (histologically or cytologically) proven diagnosis of adenocarcinoma of prostate cancer * High-risk disease defined as having at least one or more of the following: * cT3a-T3b by digital exam or imaging (American Joint Committee on Cancer \[AJCC\] 8th edition \[Ed.\]) Note: cT4 by imaging or on digital rectal exam is not allowed * The patient's prostate specific antigen (PSA) value \> 20 ng/mL prior to starting androgen deprivation therapy (ADT) Note: Patients taking a 5-alpha reductase inhibitor (ex finasteride or dutasteride) are eligible The baseline PSA value should be doubled for PSAs taken while on 5-alpha reductase inhibitors * Gleason Score of 8-10 * Pelvic node positive by conventional imaging with a short axis of at least 1.0 cm * Prostate gland volume less than 100 cc prior to initiation of ADT as reported at time of biopsy or by separate measure with ultrasound or other imaging modalities including MRI or CT scan * No definitive clinical or radiologic evidence of metastatic disease outside of the pelvic nodes (M1a, M1b or M1c) on conventional imaging (i.e. bone scan, CT scan, MRI); Negative prostate-specific membrane antigen (PSMA) positron emission tomography (PET) is an acceptable substitute * Age \>= 18 * Eastern Cooperative Oncology Group (ECOG) Performance Status of 0-2 * No prior radiotherapy to the region of the study cancer that would result in overlap of radiation therapy fields * No prior radical prostatectomy * No prior ablative or focal therapy to the prostate (including, but not limited to, transrectal or transurethral high-intensity focused ultrasound \[HIFU\], laser ablation, cryotherapy, irreversible electroporation \[IRE\], and vascular-targeted photodynamic therapy) * Prior pharmacologic androgen ablation for prostate cancer is allowed only if the onset of androgen ablation (both luteinizing hormone releasing hormone \[LHRH\] agonist and oral anti-androgen) is =\< 185 days prior to registration; Please note: PSA prior to the start of any ADT will be used to define disease * No contraindication to prostate MRI (required for planning of radiotherapy in both arms) * Patients enrolled in NRG-GU009 must be enrolled in NRG-GU013 prior to radiation therapy treatment planning and start of radiation therapy

Conditions

Prostate Adenocarcinoma Stage III Prostate Cancer AJCC v8 Stage IVA Prostate Cancer AJCC v8

Locations

  • University of Alabama at Birmingham Cancer Center — Birmingham, Alabama, United States
  • The Kirklin Clinic at Acton Road — Birmingham, Alabama, United States
  • Lewis and Faye Manderson Cancer Center — Tuscaloosa, Alabama, United States
  • University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
  • Kaiser Permanente-Deer Valley Medical Center — Antioch, California, United States
  • Tower Cancer Research Foundation — Beverly Hills, California, United States
  • Kaiser Permanente Dublin — Dublin, California, United States
  • Kaiser Permanente-Fremont — Fremont, California, United States
  • Washington Hospital — Fremont, California, United States
  • Fresno Cancer Center — Fresno, California, United States
  • Kaiser Permanente Fresno Orchard Plaza — Fresno, California, United States
  • Kaiser Permanente-Fresno — Fresno, California, United States
  • UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care — Irvine, California, United States
  • Cedars-Sinai Medical Center — Los Angeles, California, United States
  • Kaiser Permanente- Modesto MOB II — Modesto, California, United States
  • Kaiser Permanente-Modesto — Modesto, California, United States
  • Kaiser Permanente Oakland-Broadway — Oakland, California, United States
  • Kaiser Permanente-Oakland — Oakland, California, United States
  • UC Irvine Health/Chao Family Comprehensive Cancer Center — Orange, California, United States
  • Kaiser Permanente-Rancho Cordova Cancer Center — Rancho Cordova, California, United States
  • Kaiser Permanente- Marshall Medical Offices — Redwood City, California, United States
  • Kaiser Permanente-Richmond — Richmond, California, United States
  • Rohnert Park Cancer Center — Rohnert Park, California, United States
  • Kaiser Permanente-Roseville — Roseville, California, United States
  • The Permanente Medical Group-Roseville Radiation Oncology — Roseville, California, United States
  • Kaiser Permanente Downtown Commons — Sacramento, California, United States
  • Kaiser Permanente-South Sacramento — Sacramento, California, United States
  • South Sacramento Cancer Center — Sacramento, California, United States
  • Kaiser Permanente-San Francisco — San Francisco, California, United States
  • Kaiser Permanente-Santa Teresa-San Jose — San Jose, California, United States
  • Kaiser Permanente San Leandro — San Leandro, California, United States
  • Kaiser San Rafael-Gallinas — San Rafael, California, United States
  • Kaiser Permanente Medical Center - Santa Clara — Santa Clara, California, United States
  • Kaiser Permanente-Santa Rosa — Santa Rosa, California, United States
  • Kaiser Permanente Cancer Treatment Center — South San Francisco, California, United States
  • Kaiser Permanente-South San Francisco — South San Francisco, California, United States
  • Kaiser Permanente-Stockton — Stockton, California, United States
  • Torrance Memorial Physician Network - Cancer Care — Torrance, California, United States
  • Kaiser Permanente Medical Center-Vacaville — Vacaville, California, United States
  • Kaiser Permanente-Vallejo — Vallejo, California, United States
  • Kaiser Permanente-Walnut Creek — Walnut Creek, California, United States
  • UCHealth University of Colorado Hospital — Aurora, Colorado, United States
  • Rocky Mountain Cancer Centers-Penrose — Colorado Springs, Colorado, United States
  • UCHealth Memorial Hospital Central — Colorado Springs, Colorado, United States
  • Memorial Hospital North — Colorado Springs, Colorado, United States
  • UCHealth Highlands Ranch Hospital — Highlands Ranch, Colorado, United States
  • Helen F Graham Cancer Center — Newark, Delaware, United States
  • Medical Oncology Hematology Consultants PA — Newark, Delaware, United States
  • Christiana Care Health System-Wilmington Hospital — Wilmington, Delaware, United States
  • George Washington University Medical Center — Washington D.C., District of Columbia, United States
  • Mount Sinai Comprehensive Cancer Center at Aventura — Aventura, Florida, United States
  • Bay Pines VA Healthcare System — Bay Pines, Florida, United States
  • Jupiter Medical Center — Jupiter, Florida, United States
  • Mount Sinai Medical Center — Miami Beach, Florida, United States
  • Moffitt Cancer Center at SouthShore — Ruskin, Florida, United States
  • Moffitt Cancer Center-International Plaza — Tampa, Florida, United States
  • Moffitt Cancer Center - McKinley Campus — Tampa, Florida, United States
  • Moffitt Cancer Center — Tampa, Florida, United States
  • Moffitt Cancer Center at Wesley Chapel — Wesley Chapel, Florida, United States
  • Grady Health System — Atlanta, Georgia, United States
  • Emory Proton Therapy Center — Atlanta, Georgia, United States
  • Emory University Hospital Midtown — Atlanta, Georgia, United States
  • Emory University Hospital/Winship Cancer Institute — Atlanta, Georgia, United States
  • Emory Saint Joseph's Hospital — Atlanta, Georgia, United States
  • Emory Decatur Hospital — Decatur, Georgia, United States
  • Hawaii Cancer Care Inc - Waterfront Plaza — Honolulu, Hawaii, United States
  • Queen's Cancer Cenrer - POB I — Honolulu, Hawaii, United States
  • Queen's Medical Center — Honolulu, Hawaii, United States
  • Straub Clinic and Hospital — Honolulu, Hawaii, United States
  • University of Hawaii Cancer Center — Honolulu, Hawaii, United States
  • Queen's Cancer Center - Kuakini — Honolulu, Hawaii, United States
  • The Cancer Center of Hawaii-Liliha — Honolulu, Hawaii, United States
  • Kapiolani Medical Center for Women and Children — Honolulu, Hawaii, United States
  • Castle Medical Center — Kailua, Hawaii, United States
  • Wilcox Memorial Hospital and Kauai Medical Clinic — Lihue, Hawaii, United States
  • Hawaii Cancer Care - Westridge — ‘Aiea, Hawaii, United States
  • Pali Momi Medical Center — ‘Aiea, Hawaii, United States
  • The Queen's Medical Center - West Oahu — ‘Ewa Beach, Hawaii, United States
  • Alton Memorial Hospital — Alton, Illinois, United States
  • Advocate Outpatient Center - Aurora — Aurora, Illinois, United States
  • Advocate Good Shepherd Hospital — Barrington, Illinois, United States
  • Illinois CancerCare-Bloomington — Bloomington, Illinois, United States
  • Illinois CancerCare-Carthage — Carthage, Illinois, United States
  • Northwestern University — Chicago, Illinois, United States
  • University of Illinois — Chicago, Illinois, United States
  • Advocate Illinois Masonic Medical Center — Chicago, Illinois, United States
  • AMG Crystal Lake - Oncology — Crystal Lake, Illinois, United States
  • Carle at The Riverfront — Danville, Illinois, United States
  • Decatur Memorial Hospital — Decatur, Illinois, United States
  • Northwestern Medicine Cancer Center Kishwaukee — DeKalb, Illinois, United States
  • Advocate Good Samaritan Hospital — Downers Grove, Illinois, United States
  • Carle Physician Group-Effingham — Effingham, Illinois, United States
  • Crossroads Cancer Center — Effingham, Illinois, United States
  • Advocate Sherman Hospital — Elgin, Illinois, United States
  • Elmhurst Memorial Hospital — Elmhurst, Illinois, United States
  • Illinois CancerCare-Galesburg — Galesburg, Illinois, United States
  • Northwestern Medicine Cancer Center Delnor — Geneva, Illinois, United States
  • Advocate South Suburban Hospital — Hazel Crest, Illinois, United States
  • Illinois CancerCare-Kewanee Clinic — Kewanee, Illinois, United States
  • AMG Libertyville - Oncology — Libertyville, Illinois, United States
  • Condell Memorial Hospital — Libertyville, Illinois, United States
  • Illinois CancerCare-Macomb — Macomb, Illinois, United States
  • Carle Physician Group-Mattoon/Charleston — Mattoon, Illinois, United States
  • Edward Hospital/Cancer Center — Naperville, Illinois, United States
  • Cancer Care Center of O'Fallon — O'Fallon, Illinois, United States
  • HSHS Saint Elizabeth's Hospital — O'Fallon, Illinois, United States
  • Northwestern Medicine Oak Brook — Oak Brook, Illinois, United States
  • Advocate Christ Medical Center — Oak Lawn, Illinois, United States
  • Illinois CancerCare-Ottawa Clinic — Ottawa, Illinois, United States
  • Advocate High Tech Medical Park — Palos Heights, Illinois, United States
  • Advocate Lutheran General Hospital — Park Ridge, Illinois, United States
  • Illinois CancerCare-Pekin — Pekin, Illinois, United States
  • OSF Saint Francis Medical Center — Peoria, Illinois, United States
  • Illinois CancerCare-Peru — Peru, Illinois, United States
  • Illinois CancerCare-Princeton — Princeton, Illinois, United States
  • Memorial Hospital East — Shiloh, Illinois, United States
  • Southern Illinois University School of Medicine — Springfield, Illinois, United States
  • Springfield Memorial Hospital — Springfield, Illinois, United States
  • Carle Cancer Center — Urbana, Illinois, United States
  • Northwestern Medicine Cancer Center Warrenville — Warrenville, Illinois, United States
  • Goshen Center for Cancer Care — Goshen, Indiana, United States
  • McFarland Clinic - Ames — Ames, Iowa, United States
  • University of Kansas Cancer Center — Kansas City, Kansas, United States
  • Lawrence Memorial Hospital — Lawrence, Kansas, United States
  • The University of Kansas Cancer Center - Olathe — Olathe, Kansas, United States
  • University of Kansas Cancer Center-Overland Park — Overland Park, Kansas, United States
  • University of Kansas Health System Saint Francis Campus — Topeka, Kansas, United States
  • University of Kansas Hospital-Westwood Cancer Center — Westwood, Kansas, United States
  • Ascension Via Christi Hospitals Wichita — Wichita, Kansas, United States
  • Baptist Health Hardin — Elizabethtown, Kentucky, United States
  • Saint Joseph Hospital — Lexington, Kentucky, United States
  • Saint Joseph Radiation Oncology Resource Center — Lexington, Kentucky, United States
  • Saint Joseph Hospital East — Lexington, Kentucky, United States
  • The James Graham Brown Cancer Center at University of Louisville — Louisville, Kentucky, United States
  • UofL Health Medical Center Northeast — Louisville, Kentucky, United States
  • Mary Bird Perkins Cancer Center — Baton Rouge, Louisiana, United States
  • Mary Bird Perkins Cancer Center - Gonzales — Gonzales, Louisiana, United States
  • MaineHealth Coastal Cancer Treatment Center — Bath, Maine, United States
  • MaineHealth Maine Medical Center - Portland — Portland, Maine, United States
  • MaineHealth Cancer Care Center of York County — Sanford, Maine, United States
  • MaineHealth Maine Medical Center- Scarborough — Scarborough, Maine, United States
  • Maryland Proton Treatment Center — Baltimore, Maryland, United States
  • University of Maryland/Greenebaum Cancer Center — Baltimore, Maryland, United States
  • Veterans Administration Medical Center-Baltimore — Baltimore, Maryland, United States
  • Johns Hopkins University/Sidney Kimmel Cancer Center — Baltimore, Maryland, United States
  • UM Upper Chesapeake Medical Center — Bel Air, Maryland, United States
  • Central Maryland Radiation Oncology in Howard County — Columbia, Maryland, United States
  • University of Maryland Shore Medical Center at Easton — Easton, Maryland, United States
  • UM Baltimore Washington Medical Center/Tate Cancer Center — Glen Burnie, Maryland, United States
  • UM Capital Region Medical Center — Largo, Maryland, United States
  • UM Saint Joseph Medical Center — Towson, Maryland, United States
  • Brigham and Women's Hospital — Boston, Massachusetts, United States
  • Dana-Farber Cancer Institute — Boston, Massachusetts, United States
  • Dana-Farber/Brigham and Women's Cancer Center at Milford Regional — Milford, Massachusetts, United States
  • Dana-Farber/Brigham and Women's Cancer Center at South Shore — South Weymouth, Massachusetts, United States
  • Trinity Health Saint Joseph Mercy Hospital Ann Arbor — Ann Arbor, Michigan, United States
  • University of Michigan Rogel Cancer Center — Ann Arbor, Michigan, United States
  • Trinity Health Medical Center - Brighton — Brighton, Michigan, United States
  • University of Michigan - Brighton Center for Specialty Care — Brighton, Michigan, United States
  • Henry Ford Cancer Institute-Downriver — Brownstown, Michigan, United States
  • Trinity Health Medical Center - Canton — Canton, Michigan, United States
  • Chelsea Hospital — Chelsea, Michigan, United States
  • Henry Ford Macomb Hospital-Clinton Township — Clinton Township, Michigan, United States
  • Corewell Health Dearborn Hospital — Dearborn, Michigan, United States
  • Henry Ford Hospital — Detroit, Michigan, United States
  • Genesys Hurley Cancer Institute — Flint, Michigan, United States
  • Hurley Medical Center — Flint, Michigan, United States
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital — Grand Rapids, Michigan, United States
  • University of Michigan Health - Sparrow Lansing — Lansing, Michigan, United States
  • Trinity Health Saint Mary Mercy Livonia Hospital — Livonia, Michigan, United States
  • Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan, United States
  • Corewell Health William Beaumont University Hospital — Royal Oak, Michigan, United States
  • MyMichigan Medical Center Saginaw — Saginaw, Michigan, United States
  • Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center — Saint Joseph, Michigan, United States
  • Corewell Health Lakeland Hospitals - Saint Joseph Hospital — Saint Joseph, Michigan, United States
  • Munson Medical Center — Traverse City, Michigan, United States
  • Corewell Health Beaumont Troy Hospital — Troy, Michigan, United States
  • Henry Ford West Bloomfield Hospital — West Bloomfield, Michigan, United States
  • University of Michigan Health - West — Wyoming, Michigan, United States
  • Sanford Joe Lueken Cancer Center — Bemidji, Minnesota, United States
  • Essentia Health Saint Joseph's Medical Center — Brainerd, Minnesota, United States
  • Minnesota Oncology Hematology PA-Chaska — Chaska, Minnesota, United States
  • Mercy Hospital — Coon Rapids, Minnesota, United States
  • Essentia Health - Deer River Clinic — Deer River, Minnesota, United States
  • Essentia Health Cancer Center — Duluth, Minnesota, United States
  • Essentia Health Saint Mary's Medical Center — Duluth, Minnesota, United States
  • Miller-Dwan Hospital — Duluth, Minnesota, United States
  • Saint Luke's Hospital of Duluth — Duluth, Minnesota, United States
  • Fairview Southdale Hospital — Edina, Minnesota, United States
  • Essentia Health Hibbing Clinic — Hibbing, Minnesota, United States
  • Abbott-Northwestern Hospital — Minneapolis, Minnesota, United States
  • Park Nicollet Clinic - Saint Louis Park — Saint Louis Park, Minnesota, United States
  • Regions Hospital — Saint Paul, Minnesota, United States
  • United Hospital — Saint Paul, Minnesota, United States
  • Essentia Health Sandstone — Sandstone, Minnesota, United States
  • Lakeview Hospital — Stillwater, Minnesota, United States
  • Essentia Health Virginia Clinic — Virginia, Minnesota, United States
  • Ridgeview Medical Center — Waconia, Minnesota, United States
  • Saint Francis Medical Center — Cape Girardeau, Missouri, United States
  • Siteman Cancer Center at Saint Peters Hospital — City of Saint Peters, Missouri, United States
  • Siteman Cancer Center at West County Hospital — Creve Coeur, Missouri, United States
  • University of Kansas Cancer Center - North — Kansas City, Missouri, United States
  • University of Kansas Cancer Center - Lee's Summit — Lee's Summit, Missouri, United States
  • Mercy Clinic-Rolla-Cancer and Hematology — Rolla, Missouri, United States
  • Phelps Health Delbert Day Cancer Institute — Rolla, Missouri, United States
  • Mercy Hospital Springfield — Springfield, Missouri, United States
  • Washington University School of Medicine — St Louis, Missouri, United States
  • Siteman Cancer Center-South County — St Louis, Missouri, United States
  • Missouri Baptist Medical Center — St Louis, Missouri, United States
  • Siteman Cancer Center at Christian Hospital — St Louis, Missouri, United States
  • Mercy Hospital Saint Louis — St Louis, Missouri, United States
  • Billings Clinic Cancer Center — Billings, Montana, United States
  • Benefis Sletten Cancer Institute — Great Falls, Montana, United States
  • Hi-Line Sletten Cancer Center — Havre, Montana, United States
  • Nebraska Medicine-Bellevue — Bellevue, Nebraska, United States
  • Nebraska Medicine-Village Pointe — Omaha, Nebraska, United States
  • University of Nebraska Medical Center — Omaha, Nebraska, United States
  • Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center — Lebanon, New Hampshire, United States
  • Trinitas Hospital and Comprehensive Cancer Center - Williamson Street Campus — Elizabeth, New Jersey, United States
  • Jersey City Medical Center — Jersey City, New Jersey, United States
  • Saint Barnabas Medical Center — Livingston, New Jersey, United States
  • Monmouth Medical Center — Long Branch, New Jersey, United States
  • Rutgers Cancer Institute of New Jersey — New Brunswick, New Jersey, United States
  • Rutgers New Jersey Medical School — Newark, New Jersey, United States
  • Newark Beth Israel Medical Center — Newark, New Jersey, United States
  • The Valley Hospital - Luckow Pavilion — Paramus, New Jersey, United States
  • Capital Health Medical Center-Hopewell — Pennington, New Jersey, United States
  • Community Medical Center — Toms River, New Jersey, United States
  • University of New Mexico Cancer Center — Albuquerque, New Mexico, United States
  • Northwell Health Imbert Cancer Center — Bay Shore, New York, United States
  • New York-Presbyterian/Brooklyn Methodist Hospital — Brooklyn, New York, United States
  • Sands Cancer Center — Canandaigua, New York, United States
  • Noyes Memorial Hospital/Myers Cancer Center — Dansville, New York, United States
  • The New York Hospital Medical Center of Queens — Flushing, New York, United States
  • Northwell Health Physicians Partners Radiation Medicine at Queens — Forest Hills, New York, United States
  • Northwell Health Cancer Institute at Huntington — Greenlawn, New York, United States
  • Northwell Health/Center for Advanced Medicine — Lake Success, New York, United States
  • Northern Westchester Hospital — Mount Kisco, New York, United States
  • Manhattan Eye Ear and Throat Hospital — New York, New York, United States
  • Lenox Hill Hospital — New York, New York, United States
  • Upstate Cancer Center at Oswego — Oswego, New York, United States
  • Upstate Cancer Center Radiation Oncology at Oswego — Oswego, New York, United States
  • Highland Hospital — Rochester, New York, United States
  • University of Rochester — Rochester, New York, United States
  • Phelps Memorial Hospital Center — Sleepy Hollow, New York, United States
  • Stony Brook University Medical Center — Stony Brook, New York, United States
  • State University of New York Upstate Medical University — Syracuse, New York, United States
  • Upstate Cancer Center at Hill Radiation Oncology — Syracuse, New York, United States
  • Westchester Medical Center — Valhalla, New York, United States
  • Upstate Cancer Center at Verona — Verona, New York, United States
  • Wilmot Cancer Institute at Webster — Webster, New York, United States
  • Durham VA Medical Center — Durham, North Carolina, United States
  • CarolinaEast Medical Center — New Bern, North Carolina, United States
  • Sanford Roger Maris Cancer Center — Fargo, North Dakota, United States
  • Altru Cancer Center — Grand Forks, North Dakota, United States
  • Cleveland Clinic Akron General — Akron, Ohio, United States
  • UH Seidman Cancer Center at UH Avon Health Center — Avon, Ohio, United States
  • UHHS-Chagrin Highlands Medical Center — Beachwood, Ohio, United States
  • Cleveland Clinic Mercy Hospital — Canton, Ohio, United States
  • Aultman Health Foundation — Canton, Ohio, United States
  • Case Western Reserve University — Cleveland, Ohio, United States
  • Louis Stokes Cleveland VA Medical Center — Cleveland, Ohio, United States
  • MetroHealth Medical Center — Cleveland, Ohio, United States
  • Cleveland Clinic Cancer Center/Fairview Hospital — Cleveland, Ohio, United States
  • Cleveland Clinic Foundation — Cleveland, Ohio, United States
  • Ohio State University Comprehensive Cancer Center — Columbus, Ohio, United States
  • Riverside Methodist Hospital — Columbus, Ohio, United States
  • Grant Medical Center — Columbus, Ohio, United States
  • Doctors Hospital — Columbus, Ohio, United States
  • Delaware Health Center-Grady Cancer Center — Delaware, Ohio, United States
  • Grady Memorial Hospital — Delaware, Ohio, United States
  • Dublin Methodist Hospital — Dublin, Ohio, United States
  • Cleveland Clinic Cancer Center Independence — Independence, Ohio, United States
  • OhioHealth Mansfield Hospital — Mansfield, Ohio, United States
  • Cleveland Clinic Cancer Center Mansfield — Mansfield, Ohio, United States
  • OhioHealth Marion General Hospital — Marion, Ohio, United States
  • Hillcrest Hospital Cancer Center — Mayfield Heights, Ohio, United States
  • UH Seidman Cancer Center at Lake Health Mentor Campus — Mentor, Ohio, United States
  • University Hospitals Parma Medical Center — Parma, Ohio, United States
  • University Hospitals Portage Medical Center — Ravenna, Ohio, United States
  • North Coast Cancer Care — Sandusky, Ohio, United States
  • Cleveland Clinic Cancer Center Strongsville — Strongsville, Ohio, United States
  • ProMedica Flower Hospital — Sylvania, Ohio, United States
  • ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital — Toledo, Ohio, United States
  • Cleveland Clinic Wooster Family Health and Surgery Center — Wooster, Ohio, United States
  • University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma, United States
  • Saint Charles Health System — Bend, Oregon, United States
  • Clackamas Radiation Oncology Center — Clackamas, Oregon, United States
  • Providence Portland Medical Center — Portland, Oregon, United States
  • Providence Saint Vincent Medical Center — Portland, Oregon, United States
  • Kaiser Permanente Northwest — Portland, Oregon, United States
  • UPMC-Heritage Valley Health System Beaver — Beaver, Pennsylvania, United States
  • Carlisle Regional Cancer Center — Carlisle, Pennsylvania, United States
  • Christiana Care Health System-Concord Health Center — Chadds Ford, Pennsylvania, United States
  • Chambersburg Hospital — Chambersburg, Pennsylvania, United States
  • Geisinger Medical Center — Danville, Pennsylvania, United States
  • Ephrata Cancer Center — Ephrata, Pennsylvania, United States
  • UPMC Hillman Cancer Center Erie — Erie, Pennsylvania, United States
  • UPMC Cancer Center at UPMC Horizon — Farrell, Pennsylvania, United States
  • Adams Cancer Center — Gettysburg, Pennsylvania, United States
  • UPMC Cancer Centers - Arnold Palmer Pavilion — Greensburg, Pennsylvania, United States
  • UPMC Pinnacle Cancer Center/Community Osteopathic Campus — Harrisburg, Pennsylvania, United States
  • Penn State Milton S Hershey Medical Center — Hershey, Pennsylvania, United States
  • Sechler Family Cancer Center — Lebanon, Pennsylvania, United States
  • Geisinger Medical Oncology-Lewisburg — Lewisburg, Pennsylvania, United States
  • UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion — Mechanicsburg, Pennsylvania, United States
  • UPMC Cancer Center - Monroeville — Monroeville, Pennsylvania, United States
  • UPMC-Magee Womens Hospital — Pittsburgh, Pennsylvania, United States
  • UPMC-Saint Margaret — Pittsburgh, Pennsylvania, United States
  • University of Pittsburgh Cancer Institute (UPCI) — Pittsburgh, Pennsylvania, United States
  • UPMC-Shadyside Hospital — Pittsburgh, Pennsylvania, United States
  • UPMC-Passavant Hospital — Pittsburgh, Pennsylvania, United States
  • UPMC-Saint Clair Hospital Cancer Center — Pittsburgh, Pennsylvania, United States
  • Geisinger Cancer Services-Pottsville — Pottsville, Pennsylvania, United States
  • Reading Hospital — West Reading, Pennsylvania, United States
  • Geisinger Wyoming Valley/Henry Cancer Center — Wilkes-Barre, Pennsylvania, United States
  • WellSpan Health-York Cancer Center — York, Pennsylvania, United States
  • WellSpan Health-York Hospital — York, Pennsylvania, United States
  • McLeod Regional Medical Center — Florence, South Carolina, United States
  • Gibbs Cancer Center-Gaffney — Gaffney, South Carolina, United States
  • Self Regional Healthcare — Greenwood, South Carolina, United States
  • Gibbs Cancer Center-Pelham — Greer, South Carolina, United States
  • Spartanburg Medical Center — Spartanburg, South Carolina, United States
  • SMC Center for Hematology Oncology Union — Union, South Carolina, United States
  • Sanford USD Medical Center - Sioux Falls — Sioux Falls, South Dakota, United States
  • MD Anderson in The Woodlands — Conroe, Texas, United States
  • Brooke Army Medical Center — Fort Sam Houston, Texas, United States
  • UT MD Anderson Cancer Center — Houston, Texas, United States
  • MD Anderson West Houston — Houston, Texas, United States
  • UT MD Anderson - League City — League City, Texas, United States
  • MD Anderson in Sugar Land — Sugar Land, Texas, United States
  • American Fork Hospital / Huntsman Intermountain Cancer Center — American Fork, Utah, United States
  • Sandra L Maxwell Cancer Center — Cedar City, Utah, United States
  • Farmington Health Center — Farmington, Utah, United States
  • Logan Regional Hospital — Logan, Utah, United States
  • Intermountain Medical Center — Murray, Utah, United States
  • McKay-Dee Hospital Center — Ogden, Utah, United States
  • Utah Valley Regional Medical Center — Provo, Utah, United States
  • Riverton Hospital — Riverton, Utah, United States
  • University of Utah Sugarhouse Health Center — Salt Lake City, Utah, United States
  • Huntsman Cancer Institute/University of Utah — Salt Lake City, Utah, United States
  • LDS Hospital — Salt Lake City, Utah, United States
  • Saint George Regional Medical Center — St. George, Utah, United States
  • Central Vermont Medical Center/National Life Cancer Treatment — Berlin Corners, Vermont, United States
  • University of Vermont Medical Center — Burlington, Vermont, United States
  • University of Vermont and State Agricultural College — Burlington, Vermont, United States
  • Dartmouth Cancer Center - North — Saint Johnsbury, Vermont, United States
  • Augusta Health Center for Cancer and Blood Disorders — Fishersville, Virginia, United States
  • Bon Secours Memorial Regional Medical Center — Mechanicsville, Virginia, United States
  • VCU Massey Cancer Center at Hanover Medical Park — Mechanicsville, Virginia, United States
  • Bon Secours Saint Francis Medical Center — Midlothian, Virginia, United States
  • Bon Secours Saint Mary's Hospital — Richmond, Virginia, United States
  • Bon Secours Cancer Institute at Reynolds Crossing — Richmond, Virginia, United States
  • VCU Massey Cancer Center at Stony Point — Richmond, Virginia, United States
  • VCU Massey Comprehensive Cancer Center — Richmond, Virginia, United States
  • PeaceHealth Saint Joseph Medical Center — Bellingham, Washington, United States
  • Fred Hutchinson Cancer Center — Seattle, Washington, United States
  • FHCC at Northwest Hospital — Seattle, Washington, United States
  • University of Washington Medical Center - Montlake — Seattle, Washington, United States
  • Edwards Comprehensive Cancer Center — Huntington, West Virginia, United States
  • West Virginia University Healthcare — Morgantown, West Virginia, United States
  • Camden Clark Medical Center — Parkersburg, West Virginia, United States
  • Wheeling Hospital/Schiffler Cancer Center — Wheeling, West Virginia, United States
  • Langlade Hospital and Cancer Center — Antigo, Wisconsin, United States
  • Duluth Clinic Ashland — Ashland, Wisconsin, United States
  • Northwest Wisconsin Cancer Center — Ashland, Wisconsin, United States
  • Aurora Cancer Care-Southern Lakes VLCC — Burlington, Wisconsin, United States
  • Aurora Health Care Germantown Health Center — Germantown, Wisconsin, United States
  • Aurora Cancer Care-Grafton — Grafton, Wisconsin, United States
  • Saint Vincent Hospital Cancer Center Green Bay — Green Bay, Wisconsin, United States
  • Aurora BayCare Medical Center — Green Bay, Wisconsin, United States
  • Essentia Health-Hayward Clinic — Hayward, Wisconsin, United States
  • University of Wisconsin Carbone Cancer Center - Johnson Creek — Johnson Creek, Wisconsin, United States
  • Aurora Cancer Care-Kenosha South — Kenosha, Wisconsin, United States
  • University of Wisconsin Carbone Cancer Center - Eastpark Medical Center — Madison, Wisconsin, United States
  • University of Wisconsin Carbone Cancer Center - University Hospital — Madison, Wisconsin, United States
  • Aurora Bay Area Medical Group-Marinette — Marinette, Wisconsin, United States
  • Froedtert Menomonee Falls Hospital — Menomonee Falls, Wisconsin, United States
  • Aurora Cancer Care-Milwaukee — Milwaukee, Wisconsin, United States
  • Aurora Saint Luke's Medical Center — Milwaukee, Wisconsin, United States
  • Medical College of Wisconsin — Milwaukee, Wisconsin, United States
  • Aurora Sinai Medical Center — Milwaukee, Wisconsin, United States
  • Zablocki Veterans Administration Medical Center — Milwaukee, Wisconsin, United States
  • Cancer Center of Western Wisconsin — New Richmond, Wisconsin, United States
  • Drexel Town Square Health Center — Oak Creek, Wisconsin, United States
  • Vince Lombardi Cancer Clinic - Oshkosh — Oshkosh, Wisconsin, United States
  • Aurora Cancer Care-Racine — Racine, Wisconsin, United States
  • Aspirus Cancer Care - James Beck Cancer Center — Rhinelander, Wisconsin, United States
  • Saint Vincent Hospital Cancer Center at Sheboygan — Sheboygan, Wisconsin, United States
  • Sheboygan Physicians Group — Sheboygan, Wisconsin, United States
  • Vince Lombardi Cancer Clinic-Sheboygan — Sheboygan, Wisconsin, United States
  • Essentia Health-Spooner Clinic — Spooner, Wisconsin, United States
  • Aspirus Cancer Care - Stevens Point — Stevens Point, Wisconsin, United States
  • Saint Vincent Hospital Cancer Center at Sturgeon Bay — Sturgeon Bay, Wisconsin, United States
  • Aurora Medical Center in Summit — Summit, Wisconsin, United States
  • Essentia Health Saint Mary's Hospital - Superior — Superior, Wisconsin, United States
  • Vince Lombardi Cancer Clinic-Two Rivers — Two Rivers, Wisconsin, United States
  • Aspirus Regional Cancer Center — Wausau, Wisconsin, United States
  • Aurora Cancer Care-Milwaukee West — Wauwatosa, Wisconsin, United States
  • Aurora West Allis Medical Center — West Allis, Wisconsin, United States
  • Froedtert West Bend Hospital/Kraemer Cancer Center — West Bend, Wisconsin, United States
  • Aspirus Cancer Care - Wisconsin Rapids — Wisconsin Rapids, Wisconsin, United States
  • Atlantic Health Sciences Corporation-Saint John Regional Hospital — Saint John, New Brunswick, Canada
  • Ottawa Hospital and Cancer Center-General Campus — Ottawa, Ontario, Canada
  • Odette Cancer Centre- Sunnybrook Health Sciences Centre — Toronto, Ontario, Canada
  • University Health Network-Princess Margaret Hospital — Toronto, Ontario, Canada
  • CIUSSSEMTL-Hopital Maisonneuve-Rosemont — Montreal, Quebec, Canada
  • CHUM - Centre Hospitalier de l'Universite de Montreal — Montreal, Quebec, Canada
  • The Research Institute of the McGill University Health Centre (MUHC) — Montreal, Quebec, Canada
  • CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ) — Québec, Quebec, Canada
  • Centre Hospitalier Universitaire de Sherbrooke-Fleurimont — Sherbrooke, Quebec, Canada
  • Pamela Youde Nethersole Eastern Hospital — Chai Wan, Hong Kong
  • Kantonsspital Aarau — Aarau, Switzerland
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record