N
← Back to Search
Sponsored

Accelerate Your Clinical Trial Recruitment

Reach thousands of high-intent patients matching your specific inclusion criteria.

Start Campaign
RECRUITING Not applicable ClinicalTrials.gov

Hemodynamics in Chronic Hemodialysis Patients Undergoing Isolated Ultrafiltration Compared to Conventional Hemodialysis

Sponsor: Medical University of Graz • ClinicalTrials.gov ID: NCT05642156

Registry updated: 2026-10-08
Ad

Recruiting for Similar Conditions?

Sponsors are looking for patients like you. See if you qualify for compensated research studies.

Check Eligibility →

Description

Patients treated with hemodialysis (HD) bear increased risk of cardiovascular events, which results in high morbidity and mortality among this cohort of patients. Intradialytic hypotension (IDH), which is an independent risk factor for mortality, occurs in up to 20% of hemodialysis session and may lead to myocardial stunning and cerebral ischemia resulting in increased white matter lesions, gastrointestinal ischemia and shunt vessel thrombosis. Due to the deleterious effects of IDH during HD, preventive measurements such as limiting interdialytic weight gain are recommended, but frequently fluid and salt restriction are not adhered to, thus increasing dialysis time or frequency of treatments is a common strategy in those patients.

Interventions

  • isolated Ultrafiltration (iso-UF) (Procedure)
    isolated Ultrafiltration

Eligibility criteria

Inclusion Criteria: * Written consent of the participant after being informed * At least 18 years of age * End stage kidney disease patient undergoing hemodialysis * Dry weight stable for a minimum of one month * Interdialytic weight gain of \>2 liters in the short interdialytic interval Exclusion Criteria: * No informed consent was obtained * Patients with a pacemaker or implanted medical device that prevents compliance with study regulations * Patients treated with hemodiafiltration * Patients treated with medium cut-off membranes (Theranova, Baxter) * Patients with recurrent severe hyperkalemia after the short interdialytic interval (K+ concentration \> 6.0 mmol/L, requiring more than 2 hours of dialysis to ameliorate the post-dialytic shift from other compartments. * Women of childbearing age not using contraception

Conditions

End Stage Kidney Disease

Locations

  • Medical University of Graz — Graz, Austria
Sponsored

Partner with Nurenyx

Showcase your study to thousands of motivated patients matching your criteria.

Learn More

Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record