RECRUITING Phase 3 ClinicalTrials.gov

Study of Sacituzumab Govitecan-hziy and Pembrolizumab Versus Treatment of Physician's Choice in Patients With Triple Negative Breast Cancer Who Have Residual Invasive Disease After Surgery and Neoadjuvant Therapy (ASCENT-05/AFT-65 OptimICE-RD/GBG 119/NSABP B-63)

Sponsor: Gilead Sciences • ClinicalTrials.gov ID: NCT05633654

Registry updated: 2026-10-13

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Description

The goal of this study is to find out if the experimental product, sacituzumab govitecan-hziy (SG) in combination with pembrolizumab given after surgery, is effective and safe compared to the treatment of physician's choice (TPC) which includes either pembrolizumab or pembrolizumab plus capecitabine in participants with triple negative breast cancer that still remains after surgery and pre-surgical treatment.

Interventions

Sacituzumab govitecan-hziy (SG) (Drug)
Administered intravenously
Pembrolizumab (Drug)
Administered intravenously
Capecitabine (Drug)
Tablets administered orally

Eligibility criteria

Key Inclusion Criteria: * Age \> 18 years, with residual invasive triple negative breast cancer (TNBC) in the breast or lymph nodes after neoadjuvant therapy and surgery: * TNBC criteria for the study is defined as estrogen receptor (ER) and progesterone receptor (PR) ≤ 10%, human epidermal growth factor receptor 2 (HER2)-negative per American Society of Clinical Oncology and College of American Pathologists (ASCO/CAP) guidelines (immunohistochemistry (IHC) and/or in situ hybridization (ISH)). * Adequate excision and surgical removal of all clinically evident of disease in the breast and/or lymph nodes and have adequately recovered from surgery. * Submission of both pre-neoadjuvant treatment diagnostic biopsy and resected residual invasive disease tissue. * Eastern Cooperative Oncology Group (ECOG) performance status 0-1. * Individuals must have received appropriate radiotherapy aligned with local/institutional practice and have recovered prior to starting study treatment. * Adequate organ function. Key Exclusion Criteria: * Stage IV (metastatic) breast cancer as well as history of any prior (ipsi- or contralateral) invasive breast cancer. * Prior treatment with another stimulatory or coinhibitory T-cell receptor agent (eg, cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4), OX-40, cluster of differentiation 137 (CD137), prior treatment with any HER2-directed agent, prior endocrine therapy for \> 4 weeks or planned concurrent endocrine therapy while receiving on-study treatment. * Evidence of recurrent disease following preoperative therapy and surgery. * Prior treatment with topoisomerase 1 inhibitors or antibody-drug conjugates (ADCs) containing a topoisomerase inhibitor. * Individuals with germline breast cancer gene (BRCA) mutations. * Myocardial infarction or unstable angina pectoris within 6 months of enrollment or history of serious ventricular arrhythmia (ie, ventricular tachycardia or ventricular fibrillation), high-grade atrioventricular block, or other cardiac arrhythmias or Left ventricular ejection fraction (LVEF) of \< 50% * Active serious infections requiring anti-microbial therapy. Note: Other protocol defined Inclusion/Exclusion criteria may apply.

Conditions

Triple Negative Breast Cancer

Locations

Alabama Oncology — Birmingham, Alabama, United States
Clearview Cancer Institute — Huntsville, Alabama, United States
Palo Verde Hematology Oncology — Glendale, Arizona, United States
Mayo Clinic Hospital — Phoenix, Arizona, United States
Arizona Oncology Associates — Prescott Valley, Arizona, United States
Alta Bates Summit Medical Center — Berkeley, California, United States
Community Cancer Institute — Clovis, California, United States
PIH Health Whittier Hospital — Downey, California, United States
Compassionate Cancer Care Medical Group - Inc — Fountain Valley, California, United States
Los Angeles Cancer Network — Los Angeles, California, United States
USC Norris Comprehensive Cancer Center — Los Angeles, California, United States
Cedars-Sinai Cancer at Beverly Hills — Los Angeles, California, United States
Hoag Memorial Hospital Presbyterian — Newport Beach, California, United States
Emad Ibrahim, MD, INC — Redlands, California, United States
Sutter Institute for Medical Research — Sacramento, California, United States
City of Hope (Duarte) — San Francisco, California, United States
UCSF Medical Center — San Francisco, California, United States
Sansum Clinic — Santa Barbara, California, United States
Stockton Hematology Oncology Medical Group — Stockton, California, United States
University of Colorado Cancer Center — Aurora, Colorado, United States
Norwalk Hospital — Danbury, Connecticut, United States
Stamford Hospital — Stamford, Connecticut, United States
MedStar Georgetown University Hospital — Washington D.C., District of Columbia, United States
MedStar Washington Hospital Center — Washington D.C., District of Columbia, United States
Morton Plant Hospital - Bay Care — Clearwater, Florida, United States
University of Florida — Gainesville, Florida, United States
Mayo Clinic Florida — Jacksonville, Florida, United States
Cancer Specialists of North Florida — Jacksonville, Florida, United States
Jupiter Medical Center — Jupiter, Florida, United States
Mount Sinai Comprehensive Cancer Center — Miami Beach, Florida, United States
Midland Florida Clinical Research Center, L — Orange City, Florida, United States
Orlando Health — Orlando, Florida, United States
Cancer Care Centers of Brevard, Inc — Palm Bay, Florida, United States
Memorial Healthcare System — Pembroke Pines, Florida, United States
Sacred Heart Medical Oncology Group — Pensacola, Florida, United States
Sylvester Comprehensive Cancer Center — Plantation, Florida, United States
Cleveland Clinic Florida, Martin North Hospital — Stuart, Florida, United States
St. Joseph's Hospital — Tampa, Florida, United States
Weston Hospital — Weston, Florida, United States
University Cancer & Blood Center, LLC. — Athens, Georgia, United States
Piedmont Cancer Institute — Atlanta, Georgia, United States
Northside Hospital — Atlanta, Georgia, United States
Northwest Georgia Oncology Centers, PC — Marietta, Georgia, United States
Southeastern Regional Medical Center, Inc. dba City of Hope Atlanta — Newnan, Georgia, United States
Pearlman Cancer Center — Valdosta, Georgia, United States
St Lukes Mountain States Tumor Institute — Boise, Idaho, United States
Kootenai Health — Coeur d'Alene, Idaho, United States
Northwestern Medicine — Chicago, Illinois, United States
Rush University Medical Center — Chicago, Illinois, United States
University of Illinois — Chicago, Illinois, United States
University of Chicago Medical Center — Chicago, Illinois, United States
NorthShore University Healthsystem — Evanston, Illinois, United States
Edward Hospital — Naperville, Illinois, United States
West Suburban Medical Center- River Forest — River Forest, Illinois, United States
Edward H. Kaplan MD & Associates - Hematology/Oncology of the North Shore — Skokie, Illinois, United States
Springfield Clinic LLP — Springfield, Illinois, United States
Carle Cancer Center — Urbana, Illinois, United States
Franciscan Health Indianapolis — Indianapolis, Indiana, United States
Investigative Clinical Research of Indiana, LLC — Indianapolis, Indiana, United States
IU Health Arnett Hospital — Lafayette, Indiana, United States
Franciscan Health Munster — Munster, Indiana, United States
Mercy Medical Center — Cedar Rapids, Iowa, United States
Mission Cancer & Blood - John Stoddard Cancer Center — Des Moines, Iowa, United States
University of Iowa Hospitals and Clinics — Iowa City, Iowa, United States
Cancer Center of Kansas — Wichita, Kansas, United States
University of Kentucky — Lexington, Kentucky, United States
Norton Healthcare, Inc. — Louisville, Kentucky, United States
Mercy Health — Paducah, Kentucky, United States
Mary Bird Perkins Cancer Center — Baton Rouge, Louisiana, United States
University Medical Center New Orleans — New Orleans, Louisiana, United States
University Medical Center - New Orleans — New Orleans, Louisiana, United States
New England Cancer Specialists — Scarborough, Maine, United States
Sinai Hospital of Baltimore, Inc. — Baltimore, Maryland, United States
St. Agnes Hospital — Baltimore, Maryland, United States
Johns Hopkins Medicine - The Sidney Kimmel Comprehensive Cancer Center — Baltimore, Maryland, United States
American Oncology Partners of Maryland, PA — Bethesda, Maryland, United States
James M Stockman Cancer Institute — Frederick, Maryland, United States
Greater Baltimore Medical Center — Towson, Maryland, United States
Tufts Medical Center — Boston, Massachusetts, United States
Massachusetts General Hospital — Boston, Massachusetts, United States
Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
Dana Farber Cancer Institute — Boston, Massachusetts, United States
Dana-Farber Cancer Institute @Foxborough — Foxborough, Massachusetts, United States
Dana-Farber Cancer Institude at Merrimack Valley — Methuen, Massachusetts, United States
Dana Farber Cancer Institute @ Milford Regional Hospital — Milford, Massachusetts, United States
Dana-Farber/Brigham and Women's Cancer Center (DF/BWCC) in Clinical Affiliation with South Shore Hospital — South Weymouth, Massachusetts, United States
Baystate Medical Center Inc. — Springfield, Massachusetts, United States
University of Massachusetts Worcester — Worcester, Massachusetts, United States
Henry Ford Health System — Detroit, Michigan, United States
Cancer and Hematology Centers of Western Michigan — Grand Rapids, Michigan, United States
Ascension — Grosse Pointe Woods, Michigan, United States
William Beaumont Hospital — Royal Oak, Michigan, United States
Ascension Providence Hospital Southfield Cancer Center — Southfield, Michigan, United States
Trinity Health St. Joseph Mercy Ann Arbor — Ypsilanti, Michigan, United States
Minnesota Oncology Hematology, PA — Maplewood, Minnesota, United States
Virginia Piper Cancer Center (Allina Health) — Minneapolis, Minnesota, United States
University of Minnesota Medical Center, Fairview — Minneapolis, Minnesota, United States
Mayo Clinic Rochester — Rochester, Minnesota, United States
Metro Minnesota Community Oncology — Saint Louis Park, Minnesota, United States
Washington University School of Medicine — St Louis, Missouri, United States
Baptist Clinical Research Institute — St Louis, Missouri, United States
Mercy Hospital — St Louis, Missouri, United States
Mary Lanning Healthcare - Morrison Cancer Center — Hastings, Nebraska, United States
Oncology Hematology West - Methodist — Omaha, Nebraska, United States
Nebraska Methodist Hospital (change from Chi Health Bergan Mercy) — Omaha, Nebraska, United States
Comprehensive Cancer Centers of Nevada — Las Vegas, Nevada, United States
Cancer Care & Hematology Specialists — Reno, Nevada, United States
Regional Cancer Care Associates LLC — East Brunswick, New Jersey, United States
Hunterdon Medical Center — Flemington, New Jersey, United States
Summit Medical Group, P.A. — Florham Park, New Jersey, United States
Rutgers Health — New Brunswick, New Jersey, United States
Overlook Medical Center — Summit, New Jersey, United States
University of New Mexico — Albuquerque, New Mexico, United States
San Juan Oncology Associates — Farmington, New Mexico, United States
New York Oncology Hematology (NYOH) — Amsterdam, New York, United States
Roswell Park Cancer Institute — Buffalo, New York, United States
Hematology Oncology Associates of Central New York, PC — East Syracuse, New York, United States
Northwell Health — Lake Success, New York, United States
Laura and Isaac Perlmutter Cancer Canter — New York, New York, United States
Lipson Cancer Institute - Linden Oaks — Rochester, New York, United States
New York Cancer and Blood Specialists — Shirley, New York, United States
Stony Brook Medicine — Stony Brook, New York, United States
SUNY Upstate Medical University — Syracuse, New York, United States
Montefiore Medical Center — The Bronx, New York, United States
Clinical Research Alliance — Westbury, New York, United States
White Plains Hospital Physician Associates — White Plains, New York, United States
Lineberger Comprehensive Cancer Center — Chapel Hill, North Carolina, United States
Novant Health Cancer Institute - Elizabeth (Breast) — Charlotte, North Carolina, United States
Duke Cancer Institute — Durham, North Carolina, United States
Cone Health Medical Group (Moses Cone Health System) — Greensboro, North Carolina, United States
East Carolina University Health Medical Center — Greenville, North Carolina, United States
FirstHealth Outpatient Cancer Center — Pinehurst, North Carolina, United States
UNC Rex Cancer Center — Raleigh, North Carolina, United States
UNC Nash Cancer Center — Rocky Mount, North Carolina, United States
Atrium Health Wake Forest Baptist — Winston-Salem, North Carolina, United States
Good Samaritan Hospital — Cincinnati, Ohio, United States
Oncology Hematology Care, Inc. — Cincinnati, Ohio, United States
Ohio State University CRS — Columbus, Ohio, United States
Ohio Health Research Institute — Columbus, Ohio, United States
Columbus NCORP — Columbus, Ohio, United States
Anita Stewart Oncology Center — Columbus, Ohio, United States
Toledo Clinic Cancer Center — Toledo, Ohio, United States
University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma, United States
St. Charles Health System, Inc. DBA St. Charles Medical Center — Bend, Oregon, United States
Samaritan Hospital — Corvallis, Oregon, United States
Willamette Valley Cancer Institute and Research Center — Eugene, Oregon, United States
Asante Rogue Regional Medical Center — Medford, Oregon, United States
Providence Cancer Institute - Oncology Clinical Trials — Portland, Oregon, United States
Oregon Health & Science University — Portland, Oregon, United States
Saint Luke's University Hospital — Bethlehem, Pennsylvania, United States
Lancaster General Health — Lancaster, Pennsylvania, United States
University of Pennsylvania Abramson Cancer Center — Philadelphia, Pennsylvania, United States
UPMC Magee-Womens Hospital — Pittsburgh, Pennsylvania, United States
Guthrie Clinical Research — Sayre, Pennsylvania, United States
Reading Hospital and Medical Center — West Reading, Pennsylvania, United States
Lankenau Medical Center — Wynnewood, Pennsylvania, United States
Cancer Care Associates of York — York, Pennsylvania, United States
Providence Health — Providence, Rhode Island, United States
Medical University of South Carolina — Charleston, South Carolina, United States
St. Francis Cancer Center — Greenville, South Carolina, United States
Spartanburg Medical Center — Spartanburg, South Carolina, United States
Monument Health Cancer Care Institute — Rapid City, South Dakota, United States
Avera Cancer Institute — Sioux Falls, South Dakota, United States
Ballad Health Cancer Care - Kingsport — Kingsport, Tennessee, United States
Center for Biomedical Research, LLC — Knoxville, Tennessee, United States
University of Tennessee — Knoxville, Tennessee, United States
Hendrick Health System — Abilene, Texas, United States
Texas Oncology — Austin, Texas, United States
Texas Oncology — El Paso, Texas, United States
MD Anderson Cancer Center — Houston, Texas, United States
Joe Arrington Cancer Research and Treatment Center — Lubbock, Texas, United States
Texas Oncology — San Antonio, Texas, United States
Huntsman Cancer Institute — Salt Lake City, Utah, United States
University of Virginia — Charlottesville, Virginia, United States
Inova Fairfax Hospital — Fairfax, Virginia, United States
Bon Secours Cancer Institute at St. Francis — Midlothian, Virginia, United States
Virginia Commonwealth University Medical Center — Richmond, Virginia, United States
Oncology and Hematology Associates of Southwest Virginia, Inc — Wytheville, Virginia, United States
Providence Regional Cancer System — Lacey, Washington, United States
MultiCare Regional Cancer Center - Tacoma — Puyallup, Washington, United States
Northwest Medical Specialties, PLLC — Puyallup, Washington, United States
University of Washington — Renton, Washington, United States
Medical Oncology Associates — Spokane, Washington, United States
West Virginia University Hospital — Morgantown, West Virginia, United States
ThedaCare Regional Cancer Center — Appleton, Wisconsin, United States
Ascension St. Francis Reiman Cancer Center — Franklin, Wisconsin, United States
HSHS Saint Mary's Hospital Medical Center - Green Bay — Green Bay, Wisconsin, United States
University of Wisconsin — Madison, Wisconsin, United States
Macarthur Cancer Therapy Centre, Campbelltown Hospital — Campbelltown, New South Wales, Australia
Kinghorn Cancer Centre — Darlinghurst, New South Wales, Australia
Lake Macquarie Private Hospital — Gateshead, New South Wales, Australia
Port Macquarie Base Hospital — Port Macquarie, New South Wales, Australia
Cairns Hospital — Cairns, Queensland, Australia
Townsville University Hospital — Douglass, Queensland, Australia
Princess Alexandra Hospital — Woolloongabba, Queensland, Australia
Cancer Research SA — Adelaide, South Australia, Australia
Bendigo Health — Bendigo, Victoria, Australia
Monash Medical Centre — Clayton, Victoria, Australia
Fiona Stanley Hospital — Murdoch, Western Australia, Australia
Institut Jules Bordet — Anderlecht, Belgium
AZ Klina — Brasschaat, Belgium
Chirec Delta Hospital — Brussels, Belgium
Grand Hopital de Charleroi asbl (GHdC) — Gilly, Belgium
Jessa Ziekenhuis — Hasselt, Belgium
UZ Leuven — Leuven, Belgium
Clinique CHC MontLégia — Liège, Belgium
AZ Delta vzw — Roeselare, Belgium
AZ Vitaz — Sint-Niklaas, Belgium
Ziekenhuls aan de Stroom vzw (ZAS vzw), ZAS Augustinus — Wilrijk, Belgium
St. de Habitações Individuais Sul QI 15 - Lago Sul, Brasília - DF, Brasil — Brasília, Brazil
Rua Padre Germano Mayer, 1949, Hugo Lange, Curitiba, Paraná — Curitiba, Brazil
Rua Myltho Anselmo da Silva, 870 - Mercês, Curitiba - PR, CEP 80510-130 — Curitiba, Brazil
Oncosite — Ijuí, Brazil
R. Aderbal Ramos da Silva, 148 - Centro, Itajaí - SC, 88300-000, Brasil — Itajaí, Brazil
Av. Miguel Castro, 1355, Nossa Senhora de Nazaré, Natal/RN — Natal, Brazil
Rua Professor Annes Dias, 295 - Centro Histórico, Porto Alegre - RS, , Brasil — Porto Alegre, Brazil
Av. Soledad, 569, sala 1103, Três Figueiras, CEP 90470-340 — Porto Alegre, Brazil
Av. Ipiranga 6690 — Porto Alegre, Brazil
Hospital Esperança SA — Recife, Brazil
Instituto Santa Joana Recife de Ensino e Pesquisa — Recife, Brazil
Instituto D'Or de Pesquisa e Ensino - RJ — Rio de Janiero, Brazil
Av. Milton Santos, 123 - Ondina, Salvador - BA, , Brasil — Salvador, Brazil
AMO Clinic - Rio Vermelho — Salvador, Brazil
Hospital Sirio Libanês - SP — São Paulo, Brazil
Av. Brigadeiro Luís Antônio 733, loja 8 — São Paulo, Brazil
Martiiano de Carvalho 965 — São Paulo, Brazil
CIPE Centro Internacional de Pesquisa; A.C. Camargo Cancer Center — São Paulo, Brazil
Instituto D'Or de Pesquisa e Ensino SP — São Paulo, Brazil
Rua Gardênia, 710, Edifício Prime, 4º andar, Bairro Jóquei, Teresina - PI, CEP 60449-200 — Teresina, Brazil
CHU Amiens Picardie — Amiens, France
Pôle Santé Léonard De Vinci - ROC37 — Chambray-lès-Tours, France
Institut de Cancerologie de Bourgogne — Dijon, France
Clinique Victor Hugo — Le Mans, France
chu de Limoges — Limoges, France
Institut de Cancérologie de l'Ouest (ICO) - St Herblain — Loire Atlantique, France
Hôpital Privé Jean Mermoz — Lyon, France
Centre D'Oncologie de Gentilly — Nancy, France
L'Hôpital Privé du Confluent — Nantes, France
CHU de Nimes — Nîmes, France
Hopital Privé des Côtes d'Armor - Centre CARIO-HPCA — Plérin, France
CHU de Poitiers, 2 Rue de la Milétrie — Poitiers, France
Centre Eugène Marquis — Rennes, France
Clinique Ste Anne Strasbourg_Oncologie Liberale — Strasbourg, France
Oncopole Claudius Regaud - IUCT-O — Toulouse, France
Gustave Roussy — Villejuif, France
Hämatologie-Onkologie im Zentrum MVZ GmbH — Augsburg, Germany
Schwanebecker Chaussee 50 — Berlin, Germany
Möllendorffstr. 52, 10367 Berlin 2. Behandlungsstandort: Markt 2-3, 13597 Berlin — Berlin, Germany
Teutoburger Str. 60 — Bielefeld, Germany
Josef-Albers-Str.70 — Bottrop, Germany
Studien GbR Braunschweig — Braunschweig, Germany
Klinikum Bremen-Mitte — Bremen, Germany
Hämato-Onkologische Praxis im Medicum — Bremen, Germany
St. Elisabeth Krankenhaus GmbH — Cologne, Germany
St. Johannes Hospital — Dortmund, Germany
Fetscherstraße ,74 — Dresden, Germany
Kostara Gyn. Oncology Clinic Research UG — Düsseldorf, Germany
Universitätsstraße, 21-23 — Erlangen, Germany
Henricistraße 92, 45136 Essen, Germany — Essen, Germany
Klinikum Esslingen — Esslingen am Neckar, Germany
Wilhelm-Epstein-Str. 4 — Frankfurt, Germany
Gotenstraße 6-8 — Frankfurt am Main, Germany
Hugstetter Str. 55 — Freiburg im Breisgau, Germany
Munckelstrasse 27 — Gelsenkirchen, Germany
MVZ II der Niels Stensen Kliniken — Georgsmarienhütte, Germany
Straße des Friedens 122 — Gera, Germany
Hohe Weide 17b — Hamburg, Germany
Moorkamp 2-6 — Hamburg, Germany
Am Klinikum 1 — Jena, Germany
Edgar-von-Gierke-Straße 2 — Karlsruhe, Germany
Elisabeth Krankenhaus Brustzentrum — Kassel, Germany
Arnold-Heller-Str. 3 Haus C — Kiel, Germany
InVO - Institut für Versorgungsforschung in der Onkologie GbR / Praxis für Hämatologie und Onkologie — Koblenz, Germany
Lutherplatz 40 — Krefeld, Germany
Fachärztezentrum Langen — Langen, Germany
Liebigstraße 20 — Leipzig, Germany
Biedermannstrasse 84 — Leipzig, Germany
Universitätsklinikum Mannheim — Mannheim, Germany
Taxisstrasse 3 — Munich, Germany
Bei der Marienkirche 6 — Mühlhausen, Germany
Albert-Schweitzer-Campus 1, Building A1, — Münster, Germany
Starkenburgring 66, 63069 Offenbach — Offenbach, Germany
Rahel-Straus-Straße 10 — Oldenburg, Germany
Husenerstr. 81 — Paderborn, Germany
Charlottenstraße 72 — Potsdam, Germany
Elisabethenstr. 19, 88212 Ravensburg — Ravensburg, Germany
Südring 81 — Rostock, Germany
Wismarsche Strasse 393-397 — Schwerin, Germany
Harsefelderstraße 8 — Stade, Germany
Böheimstr. 37 — Stuttgart, Germany
Schierghoferstrasse 1 — Traunstrein, Germany
Calwerstrasse 7 — Tübingen, Germany
Prittwitzstr. 43 — Ulm, Germany
Beethovenstrasse 20 — Wiesbaden, Germany
Marienplatz 2 — Witten, Germany
Klinikum Worms Frauenklinik — Worms, Germany
Helios University Hospital University Witten/Herdecke — Wuppertal, Germany
Mater Misericordiae University Hospital — Dublin, Ireland
St James's Hospital — Dublin, Ireland
Beaumont Hospital — Dublin, Ireland
University Hospital Limerick — Limerick, Ireland
Cork University Hospital — Wilton, Ireland
IRCCS Istituto Tumori "Giovanni Paolo II" — Bari, Italy
IRCCS Azienda Ospedaliero-Universitaria di Bologna — Bologna, Italy
Azienda Ospedaliera Universitaria Careggi — Florence, Italy
IRCCS AOM Ospedale Policlinico San Martino — Genova, Italy
Istituto Romagnolo Per Lo Studio Dei Tumori (IRST) 'Dino Amadori? IRCCS — Meldola, Italy
Fondazione IRCCS - Istituto Nazionale dei Tumori di Milano — Milan, Italy
Humanitas Istituto Clinico Catanese — Misterbianco, Italy
AOU Modena — Modena, Italy
AOU Federico II — Naples, Italy
IRCCS Fondazione G. Pascale — Naples, Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS — Roma, Italy
Fondazione Policlinico Universitario Campus Bio-Medico di Roma — Rome, Italy
ASST Papa Giovanni XXIII — Rozzano, Italy
AOU Città della Salute e della Scienza di Torino — Torino, Italy
Ospedale Santa Chiara — Trento, Italy
Chiba Cancer Center — Chiba, Japan
The Cancer Institute Hospital of JFCR — Tokyo, Japan
Soonchunhyang University Cheonan Hospital — Chungcheongnam-do, South Korea
Kyungpook National University Chilgok Hospital — Daegu, South Korea
Seoul National University Bundang Hospital — Gyeonggi-do, South Korea
Severance Hospital — Seodaemun-gu, South Korea
Korea University Anam Hospital — Seoul, South Korea
Asan Medical Center — Seoul, South Korea
Gangnam Severance Hospital — Seoul, South Korea
Seoul National University Hospital — Seoul, South Korea
Samsung Medical Center — Seoul, South Korea
The Catholic University of Korea, Seoul St. Mary's Hospital — Seoul, South Korea
Medical Oncology Unit. A Coruña University Hospital — A Coruña, Spain
ICO Badalona - Hospital Germans Trias I Pujol — Badalona, Spain
Hospital Universitary of Cruces — Barakaldo, Spain
Hospital Clinic de Barcelona — Barcelona, Spain
Hospital del Mar — Barcelona, Spain
Hospital de la Santa Creu i Sant Pau — Barcelona, Spain
Consorcio Hospitalario Provincial de Castellón — Castellon, Spain
Hospital Universitario San Pedro de Alcántara — Cáceres, Spain
Hospital Reina Sofia — Córdoba, Spain
Hospital Donostia — Donostia / San Sebastian, Spain
Hospital General Universitario De Elche — Elche, Spain
Hospital Universitario de Fuenlabrada — Fuenlabrada, Spain
Hospital Galdakao — Galdakao, Spain
Hospital Universitario Virgen de las Nieves — Granada, Spain
Hospital Universitario Clínico San Cecilio — Granada, Spain
Hospital Universitario de Jaen — Jaén, Spain
H. León — León, Spain
Hospital Arnau de Vilanova — Lleida, Spain
Hospital Beata María Ana — Madrid, Spain
Hospital General Universitario Gregorio Maranon — Madrid, Spain
Althaia Xarxa Assistencial de Manresa — Manresa, Spain
Hospital Universitario Virgen de la Victoria — Málaga, Spain
Hosp. Mat-Inf. Carlos Haya — Málaga, Spain
Hospital General Univers — Murcia, Spain
Hospital Universitario Morales Meseguer — Murcia, Spain
Clínica Universidad de Navarra - Madrid — Pamplona, Spain
Hospital Universitari Sant Joan de Reus — Reus, Spain
Hospital Parc Tauli — Sabadell, Spain
Hospital Universitario de Canarias — San Cristóbal de La Laguna, Spain
HU Marqués de Valdecilla — Santander, Spain
Hospital Universitario Virgen Macarena — Seville, Spain
Hospital Quironsalud Sagrado Corazón — Seville, Spain
Hospital de Toledo — Toledo, Spain
Hospital Clínico Universitario de Valencia — Valencia, Spain
Hospital Clínico Universitario de Valencia — Valencia, Spain
Hospital Clinico Universitario de Valladolid — Valladolid, Spain
Isabel la Catolica nº 1-3 — Zaragoza, Spain
Hull University Teaching Hospitals NHS Trust — Cottingham, United Kingdom
University Hospitals Birmingham NHS Foundation Trust — Edgbaston, United Kingdom
The Clatterbridge Cancer Centre NHS Foundation Trust — Liverpool, United Kingdom
Barts Health NHS Trust — London, United Kingdom
Guy's Hospital — London, United Kingdom
Royal Marsden Hospital — London, United Kingdom
The Christie NHS Foundation Trust — Manchester, United Kingdom
East and North Hertfordshire NHS Trust — Northwood, United Kingdom
Taunton and Somerset NHS Foundation Trust — Taunton, United Kingdom
York Teaching Hospital NHS Foundation Trust — York, United Kingdom

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