RECRUITING Phase 2 ClinicalTrials.gov

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Sponsor: National Cancer Institute (NCI) • ClinicalTrials.gov ID: NCT05564377

Registry updated: 2026-10-15

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Description

This ComboMATCH patient screening trial is the gateway to a coordinated set of clinical trials to study cancer treatment directed by genetic testing. Patients with solid tumors that have spread to nearby tissue or lymph nodes (locally advanced) or have spread to other places in the body (advanced) and have progressed on at least one line of standard systemic therapy or have no standard treatment that has been shown to prolong overall survival may be candidates for these trials. Genetic tests look at the unique genetic material (genes) of patients' tumor cells. Patients with some genetic changes or abnormalities (mutations) may benefit from treatment that targets that particular genetic mutation. ComboMATCH is designed to match patients to a treatment that may work to control their tumor and may help doctors plan better treatment for patients with locally advanced or advanced solid tumors.

Interventions

Alpelisib (Drug)
Given PO
Binimetinib (Drug)
Given PO
Biopsy Procedure (Procedure)
Undergo biopsy
Biospecimen Collection (Procedure)
Undergo blood collection
Bone Marrow Aspiration (Procedure)
Undergo bone marrow aspiration
Bone Marrow Biopsy (Procedure)
Undergo bone marrow biopsy
Bone Scan (Procedure)
Undergo bone scan
Computed Tomography (Procedure)
Undergo CT
Echocardiography Test (Procedure)
Undergo ECHO
Fluorouracil (Drug)
Given IV
Fulvestrant (Drug)
Given IM
Ipatasertib (Drug)
Given PO
Leucovorin (Drug)
Given IV
Magnetic Resonance Imaging (Procedure)
Undergo MRI
Multigated Acquisition Scan (Procedure)
Undergo MUGA
Mutation Carrier Screening (Procedure)
Undergo tumor mutational screening
Neratinib Maleate (Drug)
Given PO
Nilotinib Hydrochloride Monohydrate (Drug)
Given PO
Olaparib (Drug)
Given PO
Oxaliplatin (Drug)
Given IV
Paclitaxel (Drug)
Given PO or IV
Palbociclib (Drug)
Given PO
Panitumumab (Biological)
Given IV
Positron Emission Tomography (Procedure)
Undergo PET
Selumetinib Sulfate (Drug)
Given PO
Sotorasib (Drug)
Given PO

Eligibility criteria

Inclusion Criteria: * Patient must have measurable disease * Patient must have an Eastern Cooperative Oncology Group (ECOG) performance status between 0-2 OR patient must have Lansky performance status of \>= 50% or Karnofsky performance status of \>= 50% * Patient must be deemed potentially eligible for a ComboMATCH Treatment Trial as assessed by the enrolling provider * All patients must have sequencing results available from a National Cancer Institute (NCI) credentialed Designated Laboratory (DL) * Patients must have locally advanced or advanced histologically documented solid tumors requiring therapy and meet one of the following criteria: * Patients must have progressed on at least one line of standard systemic therapy OR * Patients whose disease has no standard treatment that has been shown to prolong overall survival * Patient must meet one of the following requirements: * Patients 18 years and older who have tumor amenable to minimal risk image-guided or direct vision biopsy and must be willing and able to undergo a tumor biopsy to obtain samples for research if the patient is to enroll in a ComboMATCH treatment trial OR * Patients 18 years and older who do not have disease that is biopsiable at minimal risk to the patient must confirm availability of an archival tumor tissue specimen for submission for research if the patient enrolls to a ComboMATCH Treatment Trial. This tumor tissue must meet the following criteria: * Tissue must have been collected within 12 months prior to registration to the EAY191 Registration Trial * Patient must not have had a Response Evaluation Criteria in Solid Tumors (RECIST) response (complete response \[CR\] or partial response \[PR\]) to any intervening therapy after collection of the tissue * Formalin-fixed paraffin-embedded tumor tissue block(s) or slides must be available OR * Patients under 18 years old must confirm availability of an archival tumor tissue specimen for submission for research if patient enrolls to a ComboMATCH Treatment Trial. This tumor tissue must meet the following criteria: * Formalin-fixed paraffin-embedded tumor tissue block(s) or slides must be available * NOTE: See specific ComboMATCH Treatment Trial protocol for tissue collection and management instructions. Performance of the mandatory research biopsy or submission of pre-trial formalin-fixed paraffin-embedded (FFPE) and collection and submission of the blood specimens for the integrated studies will be performed under the consent authority of the specific treatment trial protocol to which the patient is registered. No procedures to collect specimens for research only are to be performed for patients registered to the EAY191 Registration Trial only * NOTE: Each ComboMATCH Treatment Trial contains specific eligibility criteria. If patient is found to not be eligible for the assigned ComboMATCH Treatment Trial, indication of ineligibility will trigger re-evaluation and potential assignment to another Treatment Trial

Conditions

Advanced Malignant Solid Neoplasm Anatomic Stage III Breast Cancer AJCC v8 Anatomic Stage IV Breast Cancer AJCC v8 Locally Advanced Malignant Solid Neoplasm Malignant Female Reproductive System Neoplasm Metastatic HER2-Negative Breast Carcinoma Metastatic Malignant Solid Neoplasm Recurrent Endometrial Carcinoma Recurrent Fallopian Tube Carcinoma Recurrent Malignant Female Reproductive System Neoplasm Recurrent Malignant Solid Neoplasm Recurrent Ovarian Carcinoma Recurrent Primary Peritoneal Carcinoma Unresectable HER2-Negative Breast Carcinoma Unresectable Malignant Solid Neoplasm

Locations

University of Alabama at Birmingham Cancer Center — Birmingham, Alabama, United States
University of South Alabama Mitchell Cancer Institute — Mobile, Alabama, United States
Alaska Women's Cancer Care — Anchorage, Alaska, United States
CTCA at Western Regional Medical Center — Goodyear, Arizona, United States
Kingman Regional Medical Center — Kingman, Arizona, United States
Mayo Clinic Hospital in Arizona — Phoenix, Arizona, United States
NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro — Jonesboro, Arkansas, United States
PCR Oncology — Arroyo Grande, California, United States
Mercy Cancer Center - Carmichael — Carmichael, California, United States
Mercy San Juan Medical Center — Carmichael, California, United States
Epic Care-Dublin — Dublin, California, United States
Mercy Cancer Center - Elk Grove — Elk Grove, California, United States
UC San Diego Health System - Encinitas — Encinitas, California, United States
UC San Diego Moores Cancer Center — La Jolla, California, United States
The Angeles Clinic and Research Institute - West Los Angeles Office — Los Angeles, California, United States
Cedars-Sinai Medical Center — Los Angeles, California, United States
Contra Costa Regional Medical Center — Martinez, California, United States
Children's Hospital of Orange County — Orange, California, United States
Saint Joseph Hospital - Orange — Orange, California, United States
Stanford Cancer Institute Palo Alto — Palo Alto, California, United States
VA Palo Alto Health Care System — Palo Alto, California, United States
Mercy Cancer Center - Rocklin — Rocklin, California, United States
Mercy Cancer Center - Sacramento — Sacramento, California, United States
UC San Diego Medical Center - Hillcrest — San Diego, California, United States
Sharp Memorial Hospital — San Diego, California, United States
UCSF Medical Center-Mission Bay — San Francisco, California, United States
Saint John's Cancer Institute — Santa Monica, California, United States
Epic Care Cyberknife Center — Walnut Creek, California, United States
Presbyterian Intercommunity Hospital — Whittier, California, United States
Woodland Memorial Hospital — Woodland, California, United States
UCHealth University of Colorado Hospital — Aurora, Colorado, United States
Poudre Valley Hospital — Fort Collins, Colorado, United States
Cancer Care and Hematology-Fort Collins — Fort Collins, Colorado, United States
UCHealth Greeley Hospital — Greeley, Colorado, United States
Medical Center of the Rockies — Loveland, Colorado, United States
Helen F Graham Cancer Center — Newark, Delaware, United States
Medical Oncology Hematology Consultants PA — Newark, Delaware, United States
UM Sylvester Comprehensive Cancer Center at Aventura — Aventura, Florida, United States
UM Sylvester Comprehensive Cancer Center at Coral Gables — Coral Gables, Florida, United States
UM Sylvester Comprehensive Cancer Center at Deerfield Beach — Deerfield Beach, Florida, United States
Broward Health Medical Center — Fort Lauderdale, Florida, United States
UF Health Cancer Institute - Gainesville — Gainesville, Florida, United States
Mayo Clinic in Florida — Jacksonville, Florida, United States
University of Miami Miller School of Medicine-Sylvester Cancer Center — Miami, Florida, United States
UM Sylvester Comprehensive Cancer Center at Kendall — Miami, Florida, United States
University of Miami Sylvester Comprehensive Cancer Center at Sole Mia — North Miami, Florida, United States
UM Sylvester Comprehensive Cancer Center at Plantation — Plantation, Florida, United States
CTCA at Southeastern Regional Medical Center — Newnan, Georgia, United States
Hawaii Cancer Care Inc - Waterfront Plaza — Honolulu, Hawaii, United States
Queen's Cancer Cenrer - POB I — Honolulu, Hawaii, United States
Queen's Medical Center — Honolulu, Hawaii, United States
Straub Clinic and Hospital — Honolulu, Hawaii, United States
University of Hawaii Cancer Center — Honolulu, Hawaii, United States
Queen's Cancer Center - Kuakini — Honolulu, Hawaii, United States
Kapiolani Medical Center for Women and Children — Honolulu, Hawaii, United States
Hawaii Cancer Care - Westridge — ‘Aiea, Hawaii, United States
Pali Momi Medical Center — ‘Aiea, Hawaii, United States
The Queen's Medical Center - West Oahu — ‘Ewa Beach, Hawaii, United States
Saint Alphonsus Cancer Care Center-Boise — Boise, Idaho, United States
Saint Luke's Cancer Institute - Boise — Boise, Idaho, United States
Saint Alphonsus Cancer Care Center-Caldwell — Caldwell, Idaho, United States
Kootenai Health - Coeur d'Alene — Coeur d'Alene, Idaho, United States
Saint Luke's Cancer Institute - Fruitland — Fruitland, Idaho, United States
Saint Luke's Cancer Institute - Meridian — Meridian, Idaho, United States
Saint Alphonsus Cancer Care Center-Nampa — Nampa, Idaho, United States
Saint Luke's Cancer Institute - Nampa — Nampa, Idaho, United States
Kootenai Clinic Cancer Services - Post Falls — Post Falls, Idaho, United States
Kootenai Clinic Cancer Services - Sandpoint — Sandpoint, Idaho, United States
Saint Luke's Cancer Institute - Twin Falls — Twin Falls, Idaho, United States
Advocate Good Shepherd Hospital — Barrington, Illinois, United States
Illinois CancerCare-Bloomington — Bloomington, Illinois, United States
Illinois CancerCare-Canton — Canton, Illinois, United States
SIH Cancer Institute — Carterville, Illinois, United States
Illinois CancerCare-Carthage — Carthage, Illinois, United States
Centralia Oncology Clinic — Centralia, Illinois, United States
Mount Sinai Hospital Medical Center — Chicago, Illinois, United States
Northwestern University — Chicago, Illinois, United States
John H Stroger Jr Hospital of Cook County — Chicago, Illinois, United States
University of Illinois — Chicago, Illinois, United States
University of Chicago Comprehensive Cancer Center — Chicago, Illinois, United States
Advocate Illinois Masonic Medical Center — Chicago, Illinois, United States
AMG Crystal Lake - Oncology — Crystal Lake, Illinois, United States
Carle at The Riverfront — Danville, Illinois, United States
Cancer Care Specialists of Illinois - Decatur — Decatur, Illinois, United States
Decatur Memorial Hospital — Decatur, Illinois, United States
Northwestern Medicine Cancer Center Kishwaukee — DeKalb, Illinois, United States
Illinois CancerCare-Dixon — Dixon, Illinois, United States
Advocate Good Samaritan Hospital — Downers Grove, Illinois, United States
Carle Physician Group-Effingham — Effingham, Illinois, United States
Crossroads Cancer Center — Effingham, Illinois, United States
Advocate Sherman Hospital — Elgin, Illinois, United States
Illinois CancerCare-Eureka — Eureka, Illinois, United States
NorthShore University HealthSystem-Evanston Hospital — Evanston, Illinois, United States
Illinois CancerCare-Galesburg — Galesburg, Illinois, United States
Northwestern Medicine Cancer Center Delnor — Geneva, Illinois, United States
NorthShore University HealthSystem-Glenbrook Hospital — Glenview, Illinois, United States
Northwestern Medicine Glenview Outpatient Center — Glenview, Illinois, United States
Northwestern Medicine Grayslake Outpatient Center — Grayslake, Illinois, United States
Ingalls Memorial Hospital — Harvey, Illinois, United States
Advocate South Suburban Hospital — Hazel Crest, Illinois, United States
NorthShore University HealthSystem-Highland Park Hospital — Highland Park, Illinois, United States
Illinois CancerCare-Kewanee Clinic — Kewanee, Illinois, United States
Northwestern Medicine Lake Forest Hospital — Lake Forest, Illinois, United States
AMG Libertyville - Oncology — Libertyville, Illinois, United States
Condell Memorial Hospital — Libertyville, Illinois, United States
Illinois CancerCare-Macomb — Macomb, Illinois, United States
Carle Physician Group-Mattoon/Charleston — Mattoon, Illinois, United States
Loyola University Medical Center — Maywood, Illinois, United States
SSM Health Good Samaritan — Mount Vernon, Illinois, United States
UC Comprehensive Cancer Center at Silver Cross — New Lenox, Illinois, United States
Carle BroMenn Medical Center — Normal, Illinois, United States
Carle Cancer Institute Normal — Normal, Illinois, United States
Cancer Care Center of O'Fallon — O'Fallon, Illinois, United States
Advocate Christ Medical Center — Oak Lawn, Illinois, United States
Northwestern Medicine Orland Park — Orland Park, Illinois, United States
University of Chicago Medicine-Orland Park — Orland Park, Illinois, United States
Illinois CancerCare-Ottawa Clinic — Ottawa, Illinois, United States
Advocate Lutheran General Hospital — Park Ridge, Illinois, United States
Illinois CancerCare-Pekin — Pekin, Illinois, United States
Illinois CancerCare-Peoria — Peoria, Illinois, United States
Illinois CancerCare-Peru — Peru, Illinois, United States
Illinois CancerCare-Princeton — Princeton, Illinois, United States
Mercyhealth Cancer Institute - Rockford — Rockford, Illinois, United States
Memorial Hospital East — Shiloh, Illinois, United States
Southern Illinois University School of Medicine — Springfield, Illinois, United States
Springfield Clinic — Springfield, Illinois, United States
Springfield Memorial Hospital — Springfield, Illinois, United States
Carle Cancer Center — Urbana, Illinois, United States
Northwestern Medicine Cancer Center Warrenville — Warrenville, Illinois, United States
Illinois CancerCare - Washington — Washington, Illinois, United States
Midwestern Regional Medical Center — Zion, Illinois, United States
UChicago Medicine Northwest Indiana — Crown Point, Indiana, United States
Woodland Cancer Care Center — Michigan City, Indiana, United States
Reid Health — Richmond, Indiana, United States
Memorial Hospital of South Bend — South Bend, Indiana, United States
UI Health Care Mission Cancer and Blood - Ankeny Clinic — Ankeny, Iowa, United States
Mercy Hospital — Cedar Rapids, Iowa, United States
Oncology Associates at Mercy Medical Center — Cedar Rapids, Iowa, United States
UI Health Care Mission Cancer and Blood - Des Moines Clinic — Des Moines, Iowa, United States
Mercy Medical Center - Des Moines — Des Moines, Iowa, United States
UI Health Care Mission Cancer and Blood - Laurel Clinic — Des Moines, Iowa, United States
UI Health Care Mission Cancer and Blood - Waukee Clinic — Waukee, Iowa, United States
CommonSpirit Saint Joseph Medical Center - East Lexington — Lexington, Kentucky, United States
University of Kentucky/Markey Cancer Center — Lexington, Kentucky, United States
Mercy Health - Paducah Cancer Center — Paducah, Kentucky, United States
East Jefferson General Hospital — Metairie, Louisiana, United States
University Medical Center New Orleans — New Orleans, Louisiana, United States
Ochsner Medical Center Jefferson — New Orleans, Louisiana, United States
Harold Alfond Center for Cancer Care — Augusta, Maine, United States
Lafayette Family Cancer Center-EMMC — Brewer, Maine, United States
MaineHealth Maine Medical Center- Scarborough — Scarborough, Maine, United States
MaineHealth Cancer Care and IV Therapy - South Portland — South Portland, Maine, United States
University of Maryland/Greenebaum Cancer Center — Baltimore, Maryland, United States
Walter Reed National Military Medical Center — Bethesda, Maryland, United States
National Institutes of Health Clinical Center — Bethesda, Maryland, United States
UPMC Western Maryland — Cumberland, Maryland, United States
Tufts Medical Center — Boston, Massachusetts, United States
Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
Dana-Farber Cancer Institute — Boston, Massachusetts, United States
Baystate Medical Center — Springfield, Massachusetts, United States
Tufts Medical Center Cancer Center Stoneham — Stoneham, Massachusetts, United States
Trinity Health Saint Joseph Mercy Hospital Ann Arbor — Ann Arbor, Michigan, United States
University of Michigan Rogel Cancer Center — Ann Arbor, Michigan, United States
Bronson Battle Creek — Battle Creek, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology - Brighton — Brighton, Michigan, United States
Trinity Health Medical Center - Brighton — Brighton, Michigan, United States
University of Michigan - Brighton Center for Specialty Care — Brighton, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology - Canton — Canton, Michigan, United States
Trinity Health Medical Center - Canton — Canton, Michigan, United States
Chelsea Hospital — Chelsea, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital — Chelsea, Michigan, United States
Corewell Health Dearborn Hospital — Dearborn, Michigan, United States
OSF Saint Francis Hospital and Medical Group — Escanaba, Michigan, United States
Corewell Health Farmington Hills Hospital — Farmington Hills, Michigan, United States
Cancer Hematology Centers - Flint — Flint, Michigan, United States
Genesee Hematology Oncology PC — Flint, Michigan, United States
Genesys Hurley Cancer Institute — Flint, Michigan, United States
Hurley Medical Center — Flint, Michigan, United States
Corewell Health Grand Rapids Hospitals - Butterworth Hospital — Grand Rapids, Michigan, United States
Trinity Health Grand Rapids Hospital — Grand Rapids, Michigan, United States
Bronson Methodist Hospital — Kalamazoo, Michigan, United States
West Michigan Cancer Center — Kalamazoo, Michigan, United States
Beacon Kalamazoo Cancer Center — Kalamazoo, Michigan, United States
Beacon Kalamazoo — Kalamazoo, Michigan, United States
University of Michigan Health - Sparrow Lansing — Lansing, Michigan, United States
Trinity Health Saint Mary Mercy Livonia Hospital — Livonia, Michigan, United States
Henry Ford Saint John Hospital - Macomb Medical — Macomb, Michigan, United States
Schoolcraft Memorial Hospital — Manistique, Michigan, United States
Trinity Health Muskegon Hospital — Muskegon, Michigan, United States
Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan, United States
Cancer and Hematology Centers of Western Michigan - Norton Shores — Norton Shores, Michigan, United States
Michigan Healthcare Professionals Pontiac — Pontiac, Michigan, United States
Trinity Health Saint Joseph Mercy Oakland Hospital — Pontiac, Michigan, United States
Corewell Health Reed City Hospital — Reed City, Michigan, United States
Corewell Health Children's — Royal Oak, Michigan, United States
Corewell Health William Beaumont University Hospital — Royal Oak, Michigan, United States
MyMichigan Medical Center Saginaw — Saginaw, Michigan, United States
Oncology Hematology Associates of Saginaw Valley PC — Saginaw, Michigan, United States
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center — Saint Joseph, Michigan, United States
Corewell Health Lakeland Hospitals - Saint Joseph Hospital — Saint Joseph, Michigan, United States
MyMichigan Medical Center Tawas — Tawas City, Michigan, United States
Munson Medical Center — Traverse City, Michigan, United States
Corewell Health Beaumont Troy Hospital — Troy, Michigan, United States
Saint Mary's Oncology/Hematology Associates of West Branch — West Branch, Michigan, United States
University of Michigan Health - West — Wyoming, Michigan, United States
Huron Gastroenterology PC — Ypsilanti, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus — Ypsilanti, Michigan, United States
Sanford Joe Lueken Cancer Center — Bemidji, Minnesota, United States
Mercy Hospital — Coon Rapids, Minnesota, United States
Essentia Health - Deer River Clinic — Deer River, Minnesota, United States
Essentia Health Cancer Center — Duluth, Minnesota, United States
Fairview Southdale Hospital — Edina, Minnesota, United States
Essentia Health Hibbing Clinic — Hibbing, Minnesota, United States
Fairview Clinics and Surgery Center Maple Grove — Maple Grove, Minnesota, United States
Saint John's Hospital - Healtheast — Maplewood, Minnesota, United States
Abbott-Northwestern Hospital — Minneapolis, Minnesota, United States
Mayo Clinic in Rochester — Rochester, Minnesota, United States
Park Nicollet Clinic - Saint Louis Park — Saint Louis Park, Minnesota, United States
Regions Hospital — Saint Paul, Minnesota, United States
United Hospital — Saint Paul, Minnesota, United States
Essentia Health Sandstone — Sandstone, Minnesota, United States
Essentia Health Virginia Clinic — Virginia, Minnesota, United States
Baptist Memorial Hospital and Cancer Center-Golden Triangle — Columbus, Mississippi, United States
Baptist Cancer Center-Grenada — Grenada, Mississippi, United States
Gulfport Memorial Hospital — Gulfport, Mississippi, United States
Baptist Memorial Hospital and Cancer Center-Union County — New Albany, Mississippi, United States
Baptist Memorial Hospital and Cancer Center-Oxford — Oxford, Mississippi, United States
Baptist Memorial Hospital and Cancer Center-Desoto — Southhaven, Mississippi, United States
Saint Francis Medical Center — Cape Girardeau, Missouri, United States
Saint Luke's Hospital — Chesterfield, Missouri, United States
Siteman Cancer Center at Saint Peters Hospital — City of Saint Peters, Missouri, United States
Siteman Cancer Center at West County Hospital — Creve Coeur, Missouri, United States
Parkland Health Center - Farmington — Farmington, Missouri, United States
Phelps Health Delbert Day Cancer Institute — Rolla, Missouri, United States
Heartland Regional Medical Center — Saint Joseph, Missouri, United States
Sainte Genevieve County Memorial Hospital — Sainte Genevieve, Missouri, United States
Mercy Hospital Springfield — Springfield, Missouri, United States
CoxHealth South Hospital — Springfield, Missouri, United States
Washington University School of Medicine — St Louis, Missouri, United States
Mercy Hospital South — St Louis, Missouri, United States
Siteman Cancer Center-South County — St Louis, Missouri, United States
Missouri Baptist Medical Center — St Louis, Missouri, United States
Siteman Cancer Center at Christian Hospital — St Louis, Missouri, United States
Mercy Hospital Saint Louis — St Louis, Missouri, United States
Missouri Baptist Sullivan Hospital — Sullivan, Missouri, United States
Community Hospital of Anaconda — Anaconda, Montana, United States
Billings Clinic Cancer Center — Billings, Montana, United States
Bozeman Health Deaconess Hospital — Bozeman, Montana, United States
Benefis Sletten Cancer Institute — Great Falls, Montana, United States
Logan Health Medical Center — Kalispell, Montana, United States
Community Medical Center — Missoula, Montana, United States
Nebraska Medicine-Bellevue — Bellevue, Nebraska, United States
Nebraska Medicine-Village Pointe — Omaha, Nebraska, United States
University of Nebraska Medical Center — Omaha, Nebraska, United States
OptumCare Cancer Care at Charleston — Las Vegas, Nevada, United States
Alliance for Childhood Diseases/Cure 4 the Kids Foundation — Las Vegas, Nevada, United States
Summerlin Hospital Medical Center — Las Vegas, Nevada, United States
OptumCare Cancer Care at Fort Apache — Las Vegas, Nevada, United States
Renown Regional Medical Center — Reno, Nevada, United States
Hunterdon Medical Center — Flemington, New Jersey, United States
Monmouth Medical Center Southern Campus — Lakewood, New Jersey, United States
Cooperman Barnabas Medical Center — Livingston, New Jersey, United States
Monmouth Medical Center — Long Branch, New Jersey, United States
Memorial Sloan Kettering Monmouth — Middletown, New Jersey, United States
Rutgers Cancer Institute of New Jersey — New Brunswick, New Jersey, United States
Capital Health Medical Center-Hopewell — Pennington, New Jersey, United States
Sidney Kimmel Cancer Center Washington Township — Sewell, New Jersey, United States
Robert Wood Johnson University Hospital Somerset — Somerville, New Jersey, United States
Community Medical Center — Toms River, New Jersey, United States
University of New Mexico Cancer Center — Albuquerque, New Mexico, United States
Roswell Park Cancer Institute — Buffalo, New York, United States
Memorial Sloan Kettering Commack — Commack, New York, United States
Memorial Sloan Kettering Westchester — Harrison, New York, United States
NYU Langone Hospital - Long Island — Mineola, New York, United States
Laura and Isaac Perlmutter Cancer Center at NYU Langone — New York, New York, United States
Mount Sinai Hospital — New York, New York, United States
Memorial Sloan Kettering Cancer Center — New York, New York, United States
Pluta Cancer Center — Rochester, New York, United States
State University of New York Upstate Medical University — Syracuse, New York, United States
Montefiore Medical Center-Einstein Campus — The Bronx, New York, United States
Montefiore Medical Center-Weiler Hospital — The Bronx, New York, United States
Montefiore Medical Center - Moses Campus — The Bronx, New York, United States
Cone Health MedCenter Asheboro — Asheboro, North Carolina, United States
Cone Health Cancer Center at Alamance Regional — Burlington, North Carolina, United States
Southeastern Medical Oncology Center-Clinton — Clinton, North Carolina, United States
Duke University Medical Center — Durham, North Carolina, United States
Southeastern Medical Oncology Center-Goldsboro — Goldsboro, North Carolina, United States
Cone Health Cancer Center — Greensboro, North Carolina, United States
Cone Health Cancer Center at Drawbridge Parkway — Greensboro, North Carolina, United States
Hayworth Cancer Center — High Point, North Carolina, United States
Southeastern Medical Oncology Center-Jacksonville — Jacksonville, North Carolina, United States
Duke Women's Cancer Care Raleigh — Raleigh, North Carolina, United States
Annie Penn Memorial Hospital — Reidsville, North Carolina, United States
Wake Forest University Health Sciences — Winston-Salem, North Carolina, United States
Sanford Bismarck Medical Center — Bismarck, North Dakota, United States
Sanford Broadway Medical Center — Fargo, North Dakota, United States
Sanford Roger Maris Cancer Center — Fargo, North Dakota, United States
OhioHealth O'Bleness Hospital — Athens, Ohio, United States
UH Seidman Cancer Center at UH Avon Health Center — Avon, Ohio, United States
UHHS-Chagrin Highlands Medical Center — Beachwood, Ohio, United States
Strecker Cancer Center-Belpre — Belpre, Ohio, United States
Aultman Health Foundation — Canton, Ohio, United States
Miami Valley Hospital South — Centerville, Ohio, United States
Adena Regional Medical Center — Chillicothe, Ohio, United States
Good Samaritan Hospital - Cincinnati — Cincinnati, Ohio, United States
Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States
Case Western Reserve University — Cleveland, Ohio, United States
Cleveland Clinic Cancer Center/Fairview Hospital — Cleveland, Ohio, United States
Cleveland Clinic Foundation — Cleveland, Ohio, United States
Ohio State University Comprehensive Cancer Center — Columbus, Ohio, United States
Mount Carmel East Hospital — Columbus, Ohio, United States
Columbus Oncology and Hematology Associates Inc — Columbus, Ohio, United States
Riverside Methodist Hospital — Columbus, Ohio, United States
Grant Medical Center — Columbus, Ohio, United States
The Mark H Zangmeister Center — Columbus, Ohio, United States
Doctors Hospital — Columbus, Ohio, United States
Miami Valley Hospital — Dayton, Ohio, United States
Premier Blood and Cancer Center — Dayton, Ohio, United States
Dayton Physician LLC - Englewood — Dayton, Ohio, United States
Miami Valley Hospital North — Dayton, Ohio, United States
Delaware Health Center-Grady Cancer Center — Delaware, Ohio, United States
Grady Memorial Hospital — Delaware, Ohio, United States
Columbus Oncology and Hematology Associates — Dublin, Ohio, United States
Dublin Methodist Hospital — Dublin, Ohio, United States
Armes Family Cancer Center — Findlay, Ohio, United States
Atrium Medical Center-Middletown Regional Hospital — Franklin, Ohio, United States
Dayton Physicians LLC-Atrium — Franklin, Ohio, United States
Miami Valley Cancer Care and Infusion — Greenville, Ohio, United States
Zangmeister Center Grove City — Grove City, Ohio, United States
Greater Dayton Cancer Center — Kettering, Ohio, United States
Kettering Medical Center — Kettering, Ohio, United States
Fairfield Medical Center — Lancaster, Ohio, United States
OhioHealth Mansfield Hospital — Mansfield, Ohio, United States
OhioHealth Marion General Hospital — Marion, Ohio, United States
Memorial Hospital — Marysville, Ohio, United States
Hillcrest Hospital Cancer Center — Mayfield Heights, Ohio, United States
UH Seidman Cancer Center at Lake Health Mentor Campus — Mentor, Ohio, United States
UH Seidman Cancer Center at Southwest General Hospital — Middleburg Heights, Ohio, United States
Knox Community Hospital — Mount Vernon, Ohio, United States
Licking Memorial Hospital — Newark, Ohio, United States
Mercy Health - Perrysburg Hospital — Perrysburg, Ohio, United States
OhioHealth Pickerington Methodist Hospital — Pickerington, Ohio, United States
Southern Ohio Medical Center — Portsmouth, Ohio, United States
Springfield Regional Cancer Center — Springfield, Ohio, United States
Springfield Regional Medical Center — Springfield, Ohio, United States
Mercy Health - Saint Anne Hospital — Toledo, Ohio, United States
Toledo Clinic Cancer Centers-Toledo — Toledo, Ohio, United States
Upper Valley Medical Center — Troy, Ohio, United States
Saint Ann's Hospital — Westerville, Ohio, United States
OhioHealth Westerville Medical Campus/Westerville Cancer Center — Westerville, Ohio, United States
Saint Elizabeth Youngstown Hospital — Youngstown, Ohio, United States
Genesis Healthcare System Cancer Care Center — Zanesville, Ohio, United States
University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma, United States
Providence Newberg Medical Center — Newberg, Oregon, United States
Saint Alphonsus Cancer Care Center-Ontario — Ontario, Oregon, United States
Providence Willamette Falls Medical Center — Oregon City, Oregon, United States
Providence Portland Medical Center — Portland, Oregon, United States
Providence Saint Vincent Medical Center — Portland, Oregon, United States
Oregon Health and Science University — Portland, Oregon, United States
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania, United States
UPMC Altoona — Altoona, Pennsylvania, United States
Lehigh Valley Hospital - Muhlenberg — Bethlehem, Pennsylvania, United States
Bryn Mawr Hospital — Bryn Mawr, Pennsylvania, United States
Pocono Medical Center — East Stroudsburg, Pennsylvania, United States
UPMC Hillman Cancer Center Erie — Erie, Pennsylvania, United States
UPMC Cancer Centers - Arnold Palmer Pavilion — Greensburg, Pennsylvania, United States
Lehigh Valley Hospital-Hazleton — Hazleton, Pennsylvania, United States
UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion — Mechanicsburg, Pennsylvania, United States
Riddle Memorial Hospital — Media, Pennsylvania, United States
UPMC Hillman Cancer Center - Monroeville — Monroeville, Pennsylvania, United States
Paoli Memorial Hospital — Paoli, Pennsylvania, United States
Pennsylvania Hospital — Philadelphia, Pennsylvania, United States
Thomas Jefferson University Hospital — Philadelphia, Pennsylvania, United States
Fox Chase Cancer Center — Philadelphia, Pennsylvania, United States
UPMC-Magee Womens Hospital — Pittsburgh, Pennsylvania, United States
UPMC Hillman Cancer Center — Pittsburgh, Pennsylvania, United States
UPMC-Passavant Hospital — Pittsburgh, Pennsylvania, United States
Guthrie Medical Group PC-Robert Packer Hospital — Sayre, Pennsylvania, United States
Asplundh Cancer Pavilion — Willow Grove, Pennsylvania, United States
Lankenau Medical Center — Wynnewood, Pennsylvania, United States
Women and Infants Hospital — Providence, Rhode Island, United States
Roger Williams Medical Center — Providence, Rhode Island, United States
Prisma Health Cancer Institute - Spartanburg — Boiling Springs, South Carolina, United States
Prisma Health Richland Hospital — Columbia, South Carolina, United States
Prisma Health Cancer Institute - Easley — Easley, South Carolina, United States
Saint Francis Hospital — Greenville, South Carolina, United States
BI-LO Charities Children's Cancer Center — Greenville, South Carolina, United States
Prisma Health Cancer Institute - Butternut — Greenville, South Carolina, United States
Prisma Health Cancer Institute - Faris — Greenville, South Carolina, United States
Saint Francis Cancer Center — Greenville, South Carolina, United States
Prisma Health Cancer Institute - Eastside — Greenville, South Carolina, United States
Prisma Health Cancer Institute - Greer — Greer, South Carolina, United States
Prisma Health Cancer Institute - Seneca — Seneca, South Carolina, United States
Rapid City Regional Hospital — Rapid City, South Dakota, United States
Sanford Cancer Center Oncology Clinic — Sioux Falls, South Dakota, United States
Sanford USD Medical Center - Sioux Falls — Sioux Falls, South Dakota, United States
Baptist Memorial Hospital and Cancer Center-Collierville — Collierville, Tennessee, United States
Regional Cancer Center at Johnson City Medical Center — Johnson City, Tennessee, United States
Ballad Health Cancer Care - Kingsport — Kingsport, Tennessee, United States
Baptist Memorial Hospital and Cancer Center-Memphis — Memphis, Tennessee, United States
Vanderbilt Breast Center at One Hundred Oaks — Nashville, Tennessee, United States
Vanderbilt University/Ingram Cancer Center — Nashville, Tennessee, United States
Hendrick Medical Center — Abilene, Texas, United States
UT Southwestern/Simmons Cancer Center-Dallas — Dallas, Texas, United States
Lyndon Baines Johnson General Hospital — Houston, Texas, United States
Houston Methodist Hospital — Houston, Texas, United States
UT MD Anderson Cancer Center — Houston, Texas, United States
Methodist Willowbrook Hospital — Houston, Texas, United States
Houston Methodist West Hospital — Houston, Texas, United States
Covenant Medical Center-Lakeside — Lubbock, Texas, United States
Houston Methodist Saint John Hospital — Nassau Bay, Texas, United States
Houston Methodist Sugar Land Hospital — Sugar Land, Texas, United States
Scott and White Memorial Hospital — Temple, Texas, United States
Houston Methodist The Woodlands Hospital — The Woodlands, Texas, United States
Ballad Health Cancer Care - Bristol — Bristol, Virginia, United States
University of Virginia Cancer Center — Charlottesville, Virginia, United States
Inova Schar Cancer Institute — Fairfax, Virginia, United States
Inova Fairfax Hospital — Falls Church, Virginia, United States
Henrico Doctor's Hospital — Richmond, Virginia, United States
Virginia Cancer Institute — Richmond, Virginia, United States
VCU Massey Cancer Center at Stony Point — Richmond, Virginia, United States
VCU Massey Comprehensive Cancer Center — Richmond, Virginia, United States
Carilion Roanoke Memorial Hospital — Roanoke, Virginia, United States
VCU Community Memorial Health Center — South Hill, Virginia, United States
Swedish Cancer Institute-Edmonds — Edmonds, Washington, United States
Swedish Cancer Institute-Issaquah — Issaquah, Washington, United States
Providence Regional Cancer System-Lacey — Lacey, Washington, United States
Valley Medical Center — Renton, Washington, United States
Swedish Medical Center-First Hill — Seattle, Washington, United States
Providence Saint Mary Regional Cancer Center — Walla Walla, Washington, United States
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital — Yakima, Washington, United States
Vandalia Health/CAMC Institute for Academic Medicine — Charleston, West Virginia, United States
Edwards Comprehensive Cancer Center — Huntington, West Virginia, United States
West Virginia University Healthcare — Morgantown, West Virginia, United States
ThedaCare Regional Cancer Center — Appleton, Wisconsin, United States
ThedaCare Regional Medical Center - Appleton — Appleton, Wisconsin, United States
Duluth Clinic Ashland — Ashland, Wisconsin, United States
ThedaCare Cancer Care - Berlin — Berlin, Wisconsin, United States
Aurora Cancer Care-Southern Lakes VLCC — Burlington, Wisconsin, United States
Marshfield Medical Center-EC Cancer Center — Eau Claire, Wisconsin, United States
Aurora Health Care Germantown Health Center — Germantown, Wisconsin, United States
Aurora Cancer Care-Grafton — Grafton, Wisconsin, United States
Saint Vincent Hospital Cancer Center Green Bay — Green Bay, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Saint Mary's — Green Bay, Wisconsin, United States
Aurora BayCare Medical Center — Green Bay, Wisconsin, United States
Mercyhealth Hospital and Cancer Center - Janesville — Janesville, Wisconsin, United States
Aurora Cancer Care-Kenosha South — Kenosha, Wisconsin, United States
Gundersen Lutheran Medical Center — La Crosse, Wisconsin, United States
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center — Madison, Wisconsin, United States
University of Wisconsin Carbone Cancer Center - University Hospital — Madison, Wisconsin, United States
Aurora Bay Area Medical Group-Marinette — Marinette, Wisconsin, United States
Marshfield Medical Center-Marshfield — Marshfield, Wisconsin, United States
Aurora Cancer Care-Milwaukee — Milwaukee, Wisconsin, United States
Aurora Saint Luke's Medical Center — Milwaukee, Wisconsin, United States
Aurora Sinai Medical Center — Milwaukee, Wisconsin, United States
Marshfield Medical Center - Minocqua — Minocqua, Wisconsin, United States
ProHealth D N Greenwald Center — Mukwonago, Wisconsin, United States
ThedaCare Regional Medical Center - Neenah — Neenah, Wisconsin, United States
ThedaCare Cancer Care - New London — New London, Wisconsin, United States
Cancer Center of Western Wisconsin — New Richmond, Wisconsin, United States
ProHealth Oconomowoc Memorial Hospital — Oconomowoc, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Oconto Falls — Oconto Falls, Wisconsin, United States
ThedaCare Cancer Care - Oshkosh — Oshkosh, Wisconsin, United States
Vince Lombardi Cancer Clinic - Oshkosh — Oshkosh, Wisconsin, United States
Aurora Cancer Care-Racine — Racine, Wisconsin, United States
Marshfield Medical Center-Rice Lake — Rice Lake, Wisconsin, United States
ThedaCare Cancer Care - Shawano — Shawano, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Sheboygan — Sheboygan, Wisconsin, United States
Sheboygan Physicians Group — Sheboygan, Wisconsin, United States
Vince Lombardi Cancer Clinic-Sheboygan — Sheboygan, Wisconsin, United States
Marshfield Medical Center-River Region at Stevens Point — Stevens Point, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Sturgeon Bay — Sturgeon Bay, Wisconsin, United States
Aurora Medical Center in Summit — Summit, Wisconsin, United States
Vince Lombardi Cancer Clinic-Two Rivers — Two Rivers, Wisconsin, United States
UW Cancer Center at ProHealth Care — Waukesha, Wisconsin, United States
ThedaCare Cancer Care - Waupaca — Waupaca, Wisconsin, United States
Aurora Cancer Care-Milwaukee West — Wauwatosa, Wisconsin, United States
Aurora West Allis Medical Center — West Allis, Wisconsin, United States
Marshfield Medical Center - Weston — Weston, Wisconsin, United States
Puerto Rico Hematology Oncology Group — Bayamón, Puerto Rico
Doctors Cancer Center — Manati, Puerto Rico
Centro Comprensivo de Cancer de UPR — San Juan, Puerto Rico
PROncology — San Juan, Puerto Rico

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