N
← Back to Search
Sponsored

Accelerate Your Clinical Trial Recruitment

Reach thousands of high-intent patients matching your specific inclusion criteria.

Start Campaign
RECRUITING Not applicable ClinicalTrials.gov

Personalized Perioperative Analgesia Platform (PPAP) for Cesarean Section

Sponsor: Senthil Sadhasivam • ClinicalTrials.gov ID: NCT05380531

Registry updated: 2026-09-10
Ad

Recruiting for Similar Conditions?

Sponsors are looking for patients like you. See if you qualify for compensated research studies.

Check Eligibility →

Description

The purpose of this collaborative CTSA (Clinical and Translational Science Award) application is to develop an innovative perioperative precision analgesia platform (PPAP) to improve analgesia and reduce serious immediate and long-term adverse outcomes of perioperative opioids in breastfeeding mothers and their infants

Interventions

  • Preoperative Genotyping (Diagnostic test)
    Genotype based risk prediction and personalized pain management

Eligibility criteria

Inclusion Criteria: Adult women (\>18 yr) All races American Society of Anesthesiologists Classification (ASA) physical status: 1 to 3 undergoing elective Cesarean section that are willing to receive in-patient opioids. Exclusion Criteria: 1. Health conditions including uncontrolled diabetes (gestational or pre-existing) or hypertension (pre-eclampsia, eclampsia, or chronic) 2. Any history of opioid misuse before or during pregnancy-per self-report and clinical notes 3. Preoperative severe pain and opioid use/misuse, allergy to oxycodone 4. Allergy to oxycodone 5. Significant neurological disorders, liver and renal diseases

Conditions

Cesarean Section Complications Opioid Use

Locations

  • Riley Children's Hospital- Clinics / Labor and Delivery Unit — Indianapolis, Indiana, United States
  • Washington University Hospital — St Louis, Missouri, United States
  • UPMC Magee Women's Hospital — Pittsburgh, Pennsylvania, United States
  • University of Pittsburgh — Pittsburgh, Pennsylvania, United States
Sponsored

Partner with Nurenyx

Showcase your study to thousands of motivated patients matching your criteria.

Learn More

Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record