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RECRUITING Not applicable ClinicalTrials.gov

Guideline Oriented Approach To Lipid Lowering In Asia-Pacific

Sponsor: Stephen Nicholls • ClinicalTrials.gov ID: NCT05325034

Registry updated: 2026-10-08
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Description

Multinational, patient-level randomised, multi-phase standard-of-care control arm, parallel group, implementation study. Patients will be recruited during hospitalisation and be randomised to a multifaceted intervention to be delivered either 'early' (baseline) or 'late' (6 months), in a 1:1 fashion.

Interventions

  • Early Intervention (Behavioral)
    Participant and clinician lipid score card to increase the likelihood of effecting guideline-directed change in lipid lowering therapy through two key actors - both the patient and their clinician(s). The Score Card documents four key fields to be completed by the participant, study team and participant's regular clinician including 1) 'current' LDL-C level, 2) participant's level of adherence to lipid-lowering therapy using modified Voil's criteria, 3) lipid-lowering management decisions made at the clinician's appointment and 4) currently prescribed lipid-lowering therapies.

Eligibility criteria

Inclusion Criteria: * 18 years of age * Admission for Type I myocardial infarction Exclusion Criteria: * LDL \<1.4mmol/L at baseline * Unable to provide contact details of primary care physician/general practitioner * Unable to provide written informed consent. * Unlikely to survive \>12 months

Conditions

Cardiovascular Diseases Acute Coronary Syndrome Atherosclerosis Hypercholesterolemia

Locations

  • Illawarra Shoalhaven Local Health District — Wollongong, New South Wales, Australia
  • Cairns & Hinterland Hospital & Health Service — Cairns, Queensland, Australia
  • Flinders Medical Centre — Bedford Park, South Australia, Australia
  • Monash Health — Clayton, Victoria, Australia
  • Western Health — Melbourne, Victoria, Australia
  • Affiliated Zhongshan Hospital of Dalian University — Dalian, Liaoning, China
  • All India Institute of Medical Sciences — New Delhi, India
  • Fukuoka University Hospital — Fukuoka, Japan
  • Kyorin University Hospital — Mitaka, Japan
  • National Cerebral and Cardiovascular Center — Osaka, Japan
  • Osaka Medical and Pharmaceutical University Hospital — Osaka, Japan
  • University Teknologi MARA, Hospital UiTM, UiTM Medical Centre — Shah Alam, Selangor, Malaysia
  • National Heart Institute — Kuala Lumpur, Malaysia
  • University of Malaysia Medical Centre — Kuala Lumpur, Malaysia
  • National Heart Centre — Singapore, Singapore
  • National University Hospital Singapore (NUHS) — Singapore, Singapore
  • PyeongChon Hallym University Sacred Heart Hospital — Pyeongchon, Gyeonggi Province, South Korea
  • Kangnam Hallym University Sacred Heart Hospital — Seoul, South Korea
  • National Cheng Kung University Hospital — Tainan, Taiwan
  • Siriraj Hospital — Bangkok, Thailand
  • Srinagarind Hospital and Queen Sirikit Heart Center of the Northeast — Khon Kaen, Thailand
  • Songklanagarind Hospital — Songkhla, Thailand
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record