N
← Back to Search
Sponsored

Accelerate Your Clinical Trial Recruitment

Reach thousands of high-intent patients matching your specific inclusion criteria.

Start Campaign
RECRUITING Not applicable ClinicalTrials.gov

Cytokine Expression in Psoriasis Patients With and Without Joint Involvement

Sponsor: Poitiers University Hospital • ClinicalTrials.gov ID: NCT05307809

Registry updated: 2026-08-31
Ad

Recruiting for Similar Conditions?

Sponsors are looking for patients like you. See if you qualify for compensated research studies.

Check Eligibility →

Description

The objective of the resarch is to study the cytokine profile of patients with psoriatic arthritis and psoriasis in order to better understand the pathophysiology of the disease and the contribution of cytokines to the presence or absence of joint involvement. This research will compare cytokines levels in sera, in PBMC culture after LPS or CD3/CD28 agonist antibodies, and in skin biopsy.

Interventions

  • Blood sample collection (Other)
    Blood sample collection
  • Skin sample collection (Other)
    Skin sample collection

Eligibility criteria

Inclusion criteria: * For psoriasis patients : * Age over 18 years old * Signed informed consent * 5 year old psoriasis at least * At least one skin lesion over 2 cm * Without any articular symptoms * Without any DMARDs * Without anticoagulant treatments or coagulation disease * With normal articular and enthesis sonography * For psoriatic arthritis patients : * Age over 18 years old * Signed informed consent * Psoriatic arthritis according to CASPAR criteria * Without any DMARDs * Without anticoagulant treatments or coagulation disease * With at least one synovitis at inclusion * For controls * Age and sex matched with a patient without any rheumatic or dermatologic medical conditions * No treatment with corticosteroïds or non-steroïdial anti-inflammatory drugsAge over 18 years old Exclusion criteria: ▪ For psoriasis patients : * Joint damage according to CASPAR criteria * Echography activity in favor of chronic inflammatory rheumatism * For patients and controls: * Without social protection rights * People under judiciary protection, of less than 18 years old, pregnant woman, breast feeding women, jailed patients.

Conditions

Psoriasis Psoriatic Arthritis

Locations

  • Chu Poitiers — Poitiers, France
Sponsored

Partner with Nurenyx

Showcase your study to thousands of motivated patients matching your criteria.

Learn More

Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record