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RECRUITING Phase 4 ClinicalTrials.gov

TES RCT Fleet Enema vs Oral Mechanical Bowel Prep

Sponsor: Nova Scotia Health Authority • ClinicalTrials.gov ID: NCT05148494

Registry updated: 2026-08-21
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Description

There is no consensus about the best bowel preparation prior to transanal endoscopic surgery TES). Cleanliness and visibility in the rectosigmoid and rectum are of utmost importance, possibly even more so than during colonoscopy, to facilitate safe, precise and efficient resection of the rectal lesion and potentially adequate closure of the defect. Both Fleet enemas and oral mechanical bowel preparation are considered standard of care in preparation for TES. This single center two arm single blinded randomized controlled trial will compare the effectiveness of Fleet enemas in comparison to Pico Salax oral mechanical bowel preparation in cleansing the rectum as measured by a modified version of the Ottawa Bowel Prep Scale.

Interventions

  • Fleet Enema (Drug)
    standard pre-op application, see arm description
  • Pico-Salax (Drug)
    standard pre-op application, see arm description

Eligibility criteria

Inclusion Criteria: * undergoing transanal endoscopic surgery at the QEII Health Sciences Center in Halifax by one of the colorectal trained surgeons Exclusion Criteria: * chronic constipation not well controlled with diet or stool softening agents * previous pelvic radiation * inflammatory bowel disease * repeat transanal surgery for the same lesion * patient unable to self-administer enemas * patient unable to tolerate either of the 2 bowel preps due to medical reasons * age over 75 * clear diagnosis of congestive heart failure * daily use of Lasix or similar loop diuretic * chronic steroid use * Transanal Endoscopic Surgery combined with another surgical procedure

Conditions

Colorectal Neoplasms Surgery

Locations

  • Victoria General Hospital — Halifax, Nova Scotia, Canada
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record