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RECRUITING Early Phase 1 ClinicalTrials.gov

Piloting Virtual Reality Environments to Treat PTSD in Healthcare Workers

Sponsor: Weill Medical College of Cornell University • ClinicalTrials.gov ID: NCT04887116

Registry updated: 2026-09-16
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Description

Healthcare workers and COVID-19 patients may experience psychological distress consequent to the pandemic, and are at particularly elevated risk for experiencing posttraumatic stress disorder (PTSD), based on evidence from previous infectious disease outbreaks. The best-validated treatment for PTSD is exposure therapy. Exposure therapy help patients suffering from PTSD to revisit and overcome their traumatic experiences. Including virtual reality in exposure therapy has a long history in treating PTSD; and has been used to treat military veterans and first-responders following 9/11. The investigators are developing and testing a virtual environment to treat PTSD including sub threshold PTSD symptoms in HCWs who experience occupational related trauma (e.g., working with COVID-19 patients) and COVID-19 patients. An independent evaluator will assess symptoms of PTSD and other psychopathology, using structured clinical interviews and self-report measures with well-established psychometric properties, at baseline, halfway through treatment, after completion of treatment, and at three-months post-treatment. Participants will complete ten ninety minute sessions (in-person or remotely), twice a week for five weeks aimed at mitigating their symptoms of PTSD. Remote participants will receive VR headsets after the baseline assessment and will keep them for the duration of the study. The pilot study will aim to demonstrate the feasibility and the tolerability of the virtual reality intervention in these populations.

Interventions

  • Virtual Reality Exposure Therapy (Behavioral)
    Ten ninety minute sessions of Virtual Reality Exposure Therapy twice a week for five weeks, either remotely or in person.

Eligibility criteria

Inclusion Criteria: * A COVID-19 patient or any healthcare worker providing medical care or support who experiences occupational-related trauma * English-speaking * Age ≥18 * Medically stable * Diagnosed with PTSD or sub threshold PTSD * Ability to provide informed consent and function at an intellectual level sufficient to allow accurate completion of all assessment instruments * Stable on psychotropic medication for the prior 60 days Exclusion Criteria: * Current significant unstable medical illness such that the participant could not attend sessions regularly or complete assessments * Patients who in the investigator's judgment pose a current homicidal, suicidal or other risk * Lifetime or Current diagnosis of schizophrenia or other psychotic disorder * Participation in a clinical trial or concurrent evidence-based treatment for psychiatric conditions or PTSD during the previous 3 months * History of motion sickness or seizures

Conditions

Posttraumatic Stress Disorder

Locations

  • Weill Cornell Medicine — New York, New York, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record