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RECRUITING Not applicable ClinicalTrials.gov

Transdiagnostic Cognitive Biomarkers

Sponsor: University of Minnesota • ClinicalTrials.gov ID: NCT04864080

Registry updated: 2026-09-15
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Description

The overall objective of this study is to determine the feasibility of identifying transdiagnostic biomarkers of cognitive function mediated by neuromodulation of the dorsolateral prefrontal cortex that are translatable across disease groups in order to more accurately phenotype clusters of cognitive dysfunction. Completing behavioral paradigms with electrophysiology and TMS is a challenging frontier. This study focuses on the feasibility of such an endeavor for those with chronic pain or depression as well as healthy controls.

Interventions

  • Computer game/task (Behavioral)
    N-back, COGED, PacMan game, Bandit task, Websurf task.
  • Health surveys online (Behavioral)
    Health surveys to study themes like pain, sleep, depression and anxiety, and PTSD.

Eligibility criteria

Arm 1, healthy controls: Inclusion Criteria: * Have access to the online study platform. Exclusion Criteria: * under 18, non-English speaking Arm 2: pain and depression: Inclusion Criteria: * Pain or depression Exclusion Criteria: * pregnant women

Conditions

Pain Depression

Locations

  • University of Minnesota — Minneapolis, Minnesota, United States
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

View Official Record