RECRUITING Phase 3 ClinicalTrials.gov

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

Sponsor: ECOG-ACRIN Cancer Research Group • ClinicalTrials.gov ID: NCT04566328

Registry updated: 2026-08-19

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Description

This phase III trial compares the combination of four drugs (daratumumab, bortezomib, lenalidomide and dexamethasone) to the use of a three drug combination (daratumumab, lenalidomide and dexamethasone). Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as lenalidomide, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Daratumumab is a monoclonal antibody that may interfere with the ability of cancer cells to grow and spread. Anti-inflammatory drugs, such as dexamethasone lower the body's immune response and are used with other drugs in the treatment of some types of cancer. Adding bortezomib to daratumumab, lenalidomide, and dexamethasone may be more effective in shrinking the cancer or preventing it from returning, compared to continuing on daratumumab, lenalidomide, and dexamethasone.

Interventions

Bortezomib (Drug)
Given SC
Daratumumab and Hyaluronidase-fihj (Biological)
Given SC
Dexamethasone (Drug)
Given PO
Lenalidomide (Drug)
Given PO
Quality-of-Life Assessment (Other)
Ancillary studies

Eligibility criteria

Inclusion Criteria: * STEP 0 - Patient must have an Eastern Cooperative Oncology Group (ECOG) performance status (PS) of 0-2 (PS 3 allowed if secondary to pain) * STEP 0 - Patient must have newly diagnosed multiple myeloma (MM) by International Myeloma Working Group (IMWG) criteria * STEP 0 - Patient must agree to register to the mandatory REVLIMID Risk Evaluation and Mitigation Strategy (RevREMS) program and be willing and able to comply with the requirements of RevREMS * STEP 0 - Patient must be able to undergo diagnostic bone marrow aspirate following preregistration. * NOTE: Bone marrow aspirate specimen must be submitted to Adaptive Biotechnologies for clonoSEQ Assay * NOTE: Adaptive Biotechnologies will release results to the diagnostic Portal from the Clonality (ID) test within fourteen (14) days of receipt and reconciliation of fresh bone marrow specimen to the submitting institution * STEP 1 - Patient must meet all eligibility criteria in STEP 0 with exception of allergy requirement * STEP 1 - Institution must have received the Clonality (ID) test results from Adaptive Biotechnologies and dominant sequences were identified * STEP 1 - Patient must have standard risk MM as defined by the Revised International Staging System (RISS) stage I or II * NOTE: R-ISS stage is based on serum beta2 microglobulin, albumin and lactate dehydrogenase (LDH) levels along with presence of chromosomal abnormalities (CA) detected by interphase fluorescent in situ hybridization (iFISH). Presence of del(17p), t(4;14), and/or t(14;16) is considered high risk and absence of these, including any other findings, are standard risk * R-ISS stage * Stage I: ISS stage I \[beta2 macroglobulin \< 3.5 mg/L, albumin \> 3.5 g/dL\] AND standard-risk CA AND normal LDH * Stage II: Not R-ISS stage I or III * Stage III: ISS stage III \[beta2 macroglobulin \> 5.5 mg/L\] AND high-risk CA OR high LDH (\> upper limit of normal) \[patients with stage III are ineligible\] * STEP 1 - Patient must have measurable or evaluable disease as defined by having one or more of the following, obtained within 28 days prior to registration: * \>= 1 g/dL monoclonal protein (M-protein) on serum protein electrophoresis * \>= 200 mg/24 hours of monoclonal protein on a 24-hour urine protein electrophoresis * Involved free light chain \>= 10 mg/dL or \>= 100 mg/L AND abnormal serum immunoglobulin kappa to lambda free light chain ratio (\< 0.26 or \> 1.65) * Monoclonal bone marrow plasmacytosis \>= 30% (evaluable disease) * STEP 1 - Patients must have a serum protein electrophoresis (SPEP), urine protein electrophoresis (UPEP), and serum free light chain (FLC) assay performed within 28 days prior to registration. In addition, a bone marrow biopsy and/or aspirate is required within 28 days if bone marrow is being followed for response * NOTE: UPEP (on a 24-hour collection) is required, no substitute method is acceptable. Urine must be followed monthly if the baseline urine M-spike is \>= 200 mg/24 hr. Please note that if both serum and urine M-components are present, both must be followed in order to evaluate response * NOTE: The serum free light chain test is required to be done if the patient does not have measurable disease in the serum or urine. Measurable disease in the serum is defined as having a serum M-spike \>= 1 g/dL. Measurable disease in the urine is defined as having a urine M-spike \>= 200 mg/24 hr * STEP 1 - Calculated creatinine clearance \> 30 mL/min (obtained =\< 14 days prior to Step 1 registration) * STEP 1 - Absolute neutrophil count (ANC) \>= 1000/mm\^3 (obtained =\< 14 days prior to Step 1 registration) * STEP 1 - Untransfused platelet count \>= 75,000/mm\^3 (obtained =\< 14 days prior to Step 1 registration) * STEP 1 - Hemoglobin \>= 8.0 g/dL (obtained =\< 14 days prior to Step 1 registration) * STEP 1 - Total bilirubin =\< 1.5 x ULN (institutional upper limit of normal) (obtained =\< 14 days prior to Step 1 registration) * STEP 1 - Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) =\< 3 x ULN (obtained =\< 14 days prior to Step 1 registration) * STEP 1 - Patient must have received no more than one cycle (28 days or less) of prior chemotherapy and no more than 160 mg of prior dexamethasone (or equivalent dose of prednisone) for treatment of symptomatic myeloma. Patient must not have been exposed to daratumumab for treatment of symptomatic myeloma. Prior radiation therapy to symptomatic lesions is allowed provided there are no residual toxicity related to radiation and blood counts meet the study requirements. Radiation treatment must be completed at least 14 days prior to Step 1 registration * STEP 1 - Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months of randomization are eligible for this trial * STEP 1 - For patients with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy, if indicated * STEP 1 - Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load * STEP 1 - Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial * STEP 1 - Patients with known history or current symptoms of cardiac disease, or history of treatment with cardiotoxic agents, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. To be eligible for this trial, patients should be class 2B or better. Patients must not have evidence of current uncontrolled cardiovascular conditions, including hypertension, cardiac arrhythmias, congestive heart failure, unstable angina, or myocardial infarction within 6 months prior to Step 1 registration * STEP 1 - Patient may have a history of current or previous deep vein thrombosis (DVT) or pulmonary embolism (PE) but must be willing to take some form of anti-coagulation as prophylaxis if they are not currently on full-dose anticoagulation * STEP 1 - Patients with a history of chronic obstructive pulmonary disease (COPD) must have FEV1 testing done within 28 days prior to Step 1 registration and the forced expiratory volume in 1 second (FEV1) must be \> 50% of predicted normal * STEP 2 - Institution must have received Tracking (MRD) test results from Adaptive Biotechnologies * STEP 2 - Patient must have completed the Step 1 Induction phase of this protocol without experiencing progression * STEP 2 - Patient must be registered to Step 2 within 8 weeks of completing Step 1 Induction Treatment, counting from last day of completion of last cycle * STEP 2 - Patient must have an ECOG performance status (PS) of 0-2 (PS 3 allowed if secondary to pain) * STEP 2 - Any adverse event(s) related to Step 1 Induction Treatment must have resolved to grade 2 or less * STEP 2 - Hemoglobin \>= 8 g/dL (obtained within 14 days prior to Step 2 randomization) * STEP 2 - Platelet count \>= 50,000/mm\^3 (obtained within 14 days prior to Step 2 randomization) * STEP 2 - Absolute neutrophil count (ANC) \>= 1000/mm\^3 (obtained within 14 days prior to Step 2 randomization) * STEP 2 - Calculated creatinine clearance \>= 30 mL/min (obtained within 14 days prior to Step 2 randomization) * STEP 2 - Total bilirubin =\< 1.5 x ULN (Institutional upper limit of normal) (obtained within 14 days prior to Step 2 randomization) * STEP 2 - ALT and AST \< 3 x ULN (obtained within 14 days prior to Step 2 randomization) Exclusion Criteria: * STEP 0 - Patient must not have any known allergies, hypersensitivity, or intolerance to corticosteroids, monoclonal antibodies or human proteins, or their excipients (refer to respective package inserts or Investigator's Brochure), or known sensitivity to mammalian-derived products * STEP 1 - Women must not be pregnant or breast-feeding due to the potential harm and teratogenic effects to an unborn fetus and possible risk for adverse events in nursing infants with the treatment regimens being used. All females of childbearing potential must have a blood test or urine study with a sensitivity of at least 25 mIU/mL within 10-14 days prior to Step 1 registration to rule out pregnancy and again within 24 hours prior to the first dose of lenalidomide. Females of childbearing potential must also agree to ongoing pregnancy testing while on protocol treatment. A female of childbearing potential is defined as any woman, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: * Has achieved menarche at some point, * Has not undergone a hysterectomy or bilateral oophorectomy; or * Has not been naturally postmenopausal (amenorrhea following cancer therapy does not rule out childbearing potential) for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months) * STEP 1 - Women of childbearing potential must not expect to conceive children by using accepted and effective method(s) of contraception (for this protocol defined as the use of TWO acceptable methods of birth control, one highly effective method and one additional effective method AT THE SAME TIME for 1) at least 28 days before starting protocol treatment; 2) while participating in the study; 3) during dose interruptions; and 4) for at least 3 months days after the last dose of protocol treatment) OR by practicing true abstinence from sexual intercourse for the duration of their participation in the study (periodic abstinence \[e.g., calendar, ovulation, symptothermal, post-ovulation methods\] and withdrawal are not acceptable methods of contraception). Men must not expect to father children by practicing true abstinence from sexual intercourse for the duration of their participation in the study (periodic abstinence \[e.g., calendar, ovulation, symptothermal, post-ovulation methods\] and withdrawal are not acceptable methods of contraception) OR use a latex condom during sexual contact with a female of child bearing potential while participating in the study and for at least 3 months after the last dose of protocol treatment even if they have had a successful vasectomy. Men must also agree to abstain from donating sperm while on study treatment and for 3 months after the last dose of protocol treatment even if they have had a successful vasectomy. Both women and men must both agree to abstain from donating blood during study participation and for at least 28 days after the last dose of protocol treatment * STEP 1 - Patient must not have peripheral neuropathy \>= grade 2 on clinical examination or grade 1 with pain at time of Step 1 registration * STEP 1 - Patient must not have any serious medical or psychiatric illness that could, in the investigator's opinion, potentially interfere with the completion of treatment according to this protocol * STEP 1 - Patient must not have moderate or severe persistent asthma within the past 2 years, or uncontrolled asthma of any classification * NOTE: Patients who currently have controlled intermittent asthma or controlled mild persistent asthma are allowed to register * STEP 1 - Patient must not receive any other concurrent chemotherapy, or any ancillary therapy considered investigational while on this protocol * NOTE: Bisphosphonates are considered to be supportive care rather than therapy, and are thus allowed while on protocol treatment * STEP 2 - Patient must not have received any non-protocol therapy outside of the assigned Step 1 Induction treatment including stem cell transplant * STEP 2 - Women must not be pregnant or breast-feeding due to the potential harm and teratogenic effects to an unborn fetus and possible risk for adverse events in nursing infants with the treatment regimens being used. All females of childbearing potential must have a blood test or urine study with a sensitivity of at least 25 mIU/mL within 10-14 days prior to Step 2 randomization to rule out pregnancy and again within 24 hours prior to the first dose of lenalidomide. Females of childbearing potential must also agree to ongoing pregnancy testing while on protocol treatment. A female of childbearing potential is defined as any woman, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: * Has achieved menarche at some point, * Has not undergone a hysterectomy or bilateral oophorectomy; or * Has not been naturally postmenopausal (amenorrhea following cancer therapy does not rule out childbearing potential) for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months). * STEP 2 - Women of childbearing potential must not expect to conceive children by using accepted and effective method(s) of contraception (for this protocol defined as the use of TWO acceptable methods of birth control, one highly effective method and one additional effective method AT THE SAME TIME for 1) at least 28 days before starting protocol treatment; 2) while participating in the study; 3) during dose interruptions; and 4) for at least 3 months days after the last dose of protocol treatment) OR by practicing true abstinence from sexual intercourse for the duration of their participation in the study (periodic abstinence \[e.g., calendar, ovulation, symptothermal, post-ovulation methods\] and withdrawal are not acceptable methods of contraception). Men must not expect to father children by practicing true abstinence from sexual intercourse for the duration of their participation in the study (periodic abstinence \[e.g., calendar, ovulation, symptothermal, post-ovulation methods\] and withdrawal are not acceptable methods of contraception) OR use a latex condom during sexual contact with a female of child bearing potential while participating in the study and for at least 3 months after the last dose of protocol treatment even if they have had a successful vasectomy. Men must also agree to abstain from donating sperm while on study treatment and for 3 months after the last dose of protocol treatment even if they have had a successful vasectomy. Both women and men must both agree to abstain from donating blood during study participation and for at least 28 days after the last dose of protocol treatment

Conditions

Plasma Cell Myeloma RISS Stage I Plasma Cell Myeloma RISS Stage II Plasma Cell Myeloma

Locations

Anchorage Associates in Radiation Medicine — Anchorage, Alaska, United States
Anchorage Radiation Therapy Center — Anchorage, Alaska, United States
Alaska Breast Care and Surgery LLC — Anchorage, Alaska, United States
Alaska Oncology and Hematology LLC — Anchorage, Alaska, United States
Alaska Women's Cancer Care — Anchorage, Alaska, United States
Anchorage Oncology Centre — Anchorage, Alaska, United States
Katmai Oncology Group — Anchorage, Alaska, United States
Providence Alaska Medical Center — Anchorage, Alaska, United States
Cancer Center at Saint Joseph's — Phoenix, Arizona, United States
University of Arizona Cancer Center-Orange Grove Campus — Tucson, Arizona, United States
Banner University Medical Center - Tucson — Tucson, Arizona, United States
University of Arizona Cancer Center-North Campus — Tucson, Arizona, United States
Mercy Hospital Fort Smith — Fort Smith, Arkansas, United States
CHI Saint Vincent Cancer Center Hot Springs — Hot Springs, Arkansas, United States
CARTI Cancer Center — Little Rock, Arkansas, United States
John L McClellan Memorial Veterans Hospital — Little Rock, Arkansas, United States
Mission Hope Medical Oncology - Arroyo Grande — Arroyo Grande, California, United States
Sutter Auburn Faith Hospital — Auburn, California, United States
Sutter Cancer Centers Radiation Oncology Services-Auburn — Auburn, California, United States
Alta Bates Summit Medical Center-Herrick Campus — Berkeley, California, United States
Providence Saint Joseph Medical Center/Disney Family Cancer Center — Burbank, California, United States
Mills-Peninsula Medical Center — Burlingame, California, United States
Sutter Cancer Centers Radiation Oncology Services-Cameron Park — Cameron Park, California, United States
Mercy Cancer Center - Carmichael — Carmichael, California, United States
Mercy San Juan Medical Center — Carmichael, California, United States
Eden Hospital Medical Center — Castro Valley, California, United States
Sutter Davis Hospital — Davis, California, United States
Mercy Cancer Center - Elk Grove — Elk Grove, California, United States
Palo Alto Medical Foundation-Fremont — Fremont, California, United States
Washington Health — Fremont, California, United States
Mercy Cancer Center — Merced, California, United States
Memorial Medical Center — Modesto, California, United States
Palo Alto Medical Foundation-Camino Division — Mountain View, California, United States
Palo Alto Medical Foundation-Gynecologic Oncology — Mountain View, California, United States
Sutter Cancer Research Consortium — Novato, California, United States
Palo Alto Medical Foundation Health Care — Palo Alto, California, United States
Mercy Cancer Center - Rocklin — Rocklin, California, United States
Sutter Cancer Centers Radiation Oncology Services-Roseville — Roseville, California, United States
Sutter Roseville Medical Center — Roseville, California, United States
Mercy Cancer Center - Sacramento — Sacramento, California, United States
Sutter Medical Center Sacramento — Sacramento, California, United States
California Pacific Medical Center-Pacific Campus — San Francisco, California, United States
Pacific Central Coast Health Center-San Luis Obispo — San Luis Obispo, California, United States
Mills Health Center — San Mateo, California, United States
Ridley-Tree Cancer Center — Santa Barbara, California, United States
Palo Alto Medical Foundation-Santa Cruz — Santa Cruz, California, United States
Santa Cruz Radiation Oncology Medical Group — Santa Cruz, California, United States
Mission Hope Medical Oncology - Santa Maria — Santa Maria, California, United States
Sutter Pacific Medical Foundation — Santa Rosa, California, United States
Saint Joseph's Medical Center — Stockton, California, United States
Palo Alto Medical Foundation-Sunnyvale — Sunnyvale, California, United States
Sutter Solano Medical Center/Cancer Center — Vallejo, California, United States
Woodland Memorial Hospital — Woodland, California, United States
Penrose-Saint Francis Healthcare — Colorado Springs, Colorado, United States
Rocky Mountain Cancer Centers-Penrose — Colorado Springs, Colorado, United States
Saint Francis Cancer Center — Colorado Springs, Colorado, United States
AdventHealth Porter — Denver, Colorado, United States
CommonSpirit Cancer Center Mercy — Durango, Colorado, United States
Mercy Medical Center — Durango, Colorado, United States
CommonSpirit Saint Anthony Hospital Cancer Center — Lakewood, Colorado, United States
AdventHealth Littleton — Littleton, Colorado, United States
Longmont United Hospital — Longmont, Colorado, United States
Rocky Mountain Cancer Centers-Longmont — Longmont, Colorado, United States
AdventHealth Parker — Parker, Colorado, United States
Saint Mary Corwin Medical Center — Pueblo, Colorado, United States
Saint Anthony North Hospital — Westminster, Colorado, United States
Smilow Cancer Hospital-Derby Care Center — Derby, Connecticut, United States
Smilow Cancer Hospital Care Center-Fairfield — Fairfield, Connecticut, United States
Smilow Cancer Hospital Care Center at Glastonbury — Glastonbury, Connecticut, United States
Smilow Cancer Hospital Care Center at Greenwich — Greenwich, Connecticut, United States
Smilow Cancer Hospital Care Center - Guilford — Guilford, Connecticut, United States
Hartford Hospital — Hartford, Connecticut, United States
Smilow Cancer Hospital Care Center at Saint Francis — Hartford, Connecticut, United States
Midstate Medical Center — Meriden, Connecticut, United States
The Hospital of Central Connecticut — New Britain, Connecticut, United States
Smilow Cancer Center/Yale-New Haven Hospital — New Haven, Connecticut, United States
Yale University — New Haven, Connecticut, United States
Yale-New Haven Hospital North Haven Medical Center — North Haven, Connecticut, United States
Smilow Cancer Hospital-Orange Care Center — Orange, Connecticut, United States
Smilow Cancer Hospital-Torrington Care Center — Torrington, Connecticut, United States
Smilow Cancer Hospital Care Center-Trumbull — Trumbull, Connecticut, United States
Smilow Cancer Hospital-Waterbury Care Center — Waterbury, Connecticut, United States
Smilow Cancer Hospital Care Center - Waterford — Waterford, Connecticut, United States
Beebe Medical Center — Lewes, Delaware, United States
Beebe South Coastal Health Campus — Millville, Delaware, United States
Delaware Clinical and Laboratory Physicians PA — Newark, Delaware, United States
Helen F Graham Cancer Center — Newark, Delaware, United States
Medical Oncology Hematology Consultants PA — Newark, Delaware, United States
Christiana Care Health System-Christiana Hospital — Newark, Delaware, United States
Beebe Health Campus — Rehoboth Beach, Delaware, United States
TidalHealth Nanticoke / Allen Cancer Center — Seaford, Delaware, United States
Christiana Care Health System-Wilmington Hospital — Wilmington, Delaware, United States
Sibley Memorial Hospital — Washington D.C., District of Columbia, United States
Holy Cross Hospital — Fort Lauderdale, Florida, United States
University of Florida Health Science Center - Jacksonville — Jacksonville, Florida, United States
Sacred Heart Hospital — Pensacola, Florida, United States
Saint Alphonsus Cancer Care Center-Boise — Boise, Idaho, United States
Saint Luke's Cancer Institute - Boise — Boise, Idaho, United States
Saint Alphonsus Cancer Care Center-Caldwell — Caldwell, Idaho, United States
Kootenai Health - Coeur d'Alene — Coeur d'Alene, Idaho, United States
Walter Knox Memorial Hospital — Emmett, Idaho, United States
Saint Luke's Cancer Institute - Fruitland — Fruitland, Idaho, United States
Idaho Urologic Institute-Meridian — Meridian, Idaho, United States
Saint Luke's Cancer Institute - Meridian — Meridian, Idaho, United States
Saint Alphonsus Cancer Care Center-Nampa — Nampa, Idaho, United States
Saint Luke's Cancer Institute - Nampa — Nampa, Idaho, United States
Kootenai Clinic Cancer Services - Post Falls — Post Falls, Idaho, United States
Kootenai Clinic Cancer Services - Sandpoint — Sandpoint, Idaho, United States
Saint Luke's Cancer Institute - Twin Falls — Twin Falls, Idaho, United States
OSF Saint Anthony's Health Center — Alton, Illinois, United States
Rush-Copley Medical Center — Aurora, Illinois, United States
Advocate Outpatient Center - Aurora — Aurora, Illinois, United States
Advocate Good Shepherd Hospital — Barrington, Illinois, United States
Illinois CancerCare-Bloomington — Bloomington, Illinois, United States
Loyola Center for Health at Burr Ridge — Burr Ridge, Illinois, United States
Illinois CancerCare-Canton — Canton, Illinois, United States
Memorial Hospital of Carbondale — Carbondale, Illinois, United States
SIH Cancer Institute — Carterville, Illinois, United States
Illinois CancerCare-Carthage — Carthage, Illinois, United States
Centralia Oncology Clinic — Centralia, Illinois, United States
Saint Mary's Hospital — Centralia, Illinois, United States
Mount Sinai Hospital Medical Center — Chicago, Illinois, United States
John H Stroger Jr Hospital of Cook County — Chicago, Illinois, United States
University of Illinois — Chicago, Illinois, United States
Advocate Illinois Masonic Medical Center — Chicago, Illinois, United States
AMG Crystal Lake - Oncology — Crystal Lake, Illinois, United States
Carle at The Riverfront — Danville, Illinois, United States
Cancer Care Specialists of Illinois - Decatur — Decatur, Illinois, United States
Decatur Memorial Hospital — Decatur, Illinois, United States
Northwestern Medicine Cancer Center Kishwaukee — DeKalb, Illinois, United States
Illinois CancerCare-Dixon — Dixon, Illinois, United States
Advocate Good Samaritan Hospital — Downers Grove, Illinois, United States
Carle Physician Group-Effingham — Effingham, Illinois, United States
Crossroads Cancer Center — Effingham, Illinois, United States
Advocate Sherman Hospital — Elgin, Illinois, United States
Illinois CancerCare-Eureka — Eureka, Illinois, United States
Illinois CancerCare-Galesburg — Galesburg, Illinois, United States
Western Illinois Cancer Treatment Center — Galesburg, Illinois, United States
Northwestern Medicine Cancer Center Delnor — Geneva, Illinois, United States
Advocate South Suburban Hospital — Hazel Crest, Illinois, United States
Loyola Medicine Homer Glen — Homer Glen, Illinois, United States
Illinois CancerCare-Kewanee Clinic — Kewanee, Illinois, United States
AMG Libertyville - Oncology — Libertyville, Illinois, United States
Condell Memorial Hospital — Libertyville, Illinois, United States
Illinois CancerCare-Macomb — Macomb, Illinois, United States
Carle Physician Group-Mattoon/Charleston — Mattoon, Illinois, United States
Loyola University Medical Center — Maywood, Illinois, United States
Marjorie Weinberg Cancer Center at Loyola-Gottlieb — Melrose Park, Illinois, United States
SSM Health Good Samaritan — Mount Vernon, Illinois, United States
Carle BroMenn Medical Center — Normal, Illinois, United States
Carle Cancer Institute Normal — Normal, Illinois, United States
Cancer Care Center of O'Fallon — O'Fallon, Illinois, United States
HSHS Saint Elizabeth's Hospital — O'Fallon, Illinois, United States
Advocate Christ Medical Center — Oak Lawn, Illinois, United States
Illinois CancerCare-Ottawa Clinic — Ottawa, Illinois, United States
Advocate Lutheran General Hospital — Park Ridge, Illinois, United States
Illinois CancerCare-Pekin — Pekin, Illinois, United States
Illinois CancerCare-Peoria — Peoria, Illinois, United States
Methodist Medical Center of Illinois — Peoria, Illinois, United States
Illinois CancerCare-Peru — Peru, Illinois, United States
Valley Radiation Oncology — Peru, Illinois, United States
Illinois CancerCare-Princeton — Princeton, Illinois, United States
UW Health Carbone Cancer Center Rockford — Rockford, Illinois, United States
Southern Illinois University School of Medicine — Springfield, Illinois, United States
Springfield Clinic — Springfield, Illinois, United States
Springfield Memorial Hospital — Springfield, Illinois, United States
Carle Cancer Center — Urbana, Illinois, United States
The Carle Foundation Hospital — Urbana, Illinois, United States
Northwestern Medicine Cancer Center Warrenville — Warrenville, Illinois, United States
Illinois CancerCare - Washington — Washington, Illinois, United States
Rush-Copley Healthcare Center — Yorkville, Illinois, United States
IU Health North Hospital — Carmel, Indiana, United States
Indiana University/Melvin and Bren Simon Cancer Center — Indianapolis, Indiana, United States
IU Health Methodist Hospital — Indianapolis, Indiana, United States
Reid Health — Richmond, Indiana, United States
Mary Greeley Medical Center — Ames, Iowa, United States
McFarland Clinic - Ames — Ames, Iowa, United States
UI Health Care Mission Cancer and Blood - Ankeny Clinic — Ankeny, Iowa, United States
McFarland Clinic - Boone — Boone, Iowa, United States
Saint Anthony Regional Hospital — Carroll, Iowa, United States
Mercy Hospital — Cedar Rapids, Iowa, United States
Oncology Associates at Mercy Medical Center — Cedar Rapids, Iowa, United States
Mercy Cancer Center-West Lakes — Clive, Iowa, United States
UI Health Care Mission Cancer and Blood - West Des Moines Clinic — Clive, Iowa, United States
Alegent Health Mercy Hospital — Council Bluffs, Iowa, United States
Greater Regional Medical Center — Creston, Iowa, United States
Iowa Methodist Medical Center — Des Moines, Iowa, United States
UI Health Care Mission Cancer and Blood - Des Moines Clinic — Des Moines, Iowa, United States
Broadlawns Medical Center — Des Moines, Iowa, United States
Mercy Medical Center - Des Moines — Des Moines, Iowa, United States
UI Health Care Mission Cancer and Blood - Laurel Clinic — Des Moines, Iowa, United States
Iowa Lutheran Hospital — Des Moines, Iowa, United States
McFarland Clinic - Trinity Cancer Center — Fort Dodge, Iowa, United States
UI Healthcare Mission Cancer and Blood - Fort Dodge — Fort Dodge, Iowa, United States
McFarland Clinic - Jefferson — Jefferson, Iowa, United States
McFarland Clinic - Marshalltown — Marshalltown, Iowa, United States
Siouxland Regional Cancer Center — Sioux City, Iowa, United States
UI Health Care Mission Cancer and Blood - Waukee Clinic — Waukee, Iowa, United States
Methodist West Hospital — West Des Moines, Iowa, United States
Mercy Medical Center-West Lakes — West Des Moines, Iowa, United States
Cancer Center of Kansas - Chanute — Chanute, Kansas, United States
Cancer Center of Kansas - Dodge City — Dodge City, Kansas, United States
Cancer Center of Kansas - El Dorado — El Dorado, Kansas, United States
Central Care Cancer Center - Garden City — Garden City, Kansas, United States
Central Care Cancer Center - Great Bend — Great Bend, Kansas, United States
Cancer Center of Kansas-Independence — Independence, Kansas, United States
Cancer Center of Kansas-Kingman — Kingman, Kansas, United States
Cancer Center of Kansas-Liberal — Liberal, Kansas, United States
Cancer Center of Kansas-Manhattan — Manhattan, Kansas, United States
Cancer Center of Kansas - McPherson — McPherson, Kansas, United States
Cancer Center of Kansas - Newton — Newton, Kansas, United States
Cancer Center of Kansas - Parsons — Parsons, Kansas, United States
Mercy Hospital Pittsburg — Pittsburg, Kansas, United States
Cancer Center of Kansas - Pratt — Pratt, Kansas, United States
Cancer Center of Kansas - Salina — Salina, Kansas, United States
Cancer Center of Kansas - Wellington — Wellington, Kansas, United States
Cancer Center of Kansas-Wichita Medical Arts Tower — Wichita, Kansas, United States
Ascension Via Christi Hospitals Wichita — Wichita, Kansas, United States
Cancer Center of Kansas - Wichita — Wichita, Kansas, United States
Cancer Center of Kansas - Winfield — Winfield, Kansas, United States
CommonSpirit Saint Joseph Hospital - Bardstown — Bardstown, Kentucky, United States
Commonwealth Cancer Center-Corbin — Corbin, Kentucky, United States
CommonSpirit Saint Joseph Hospital - Lexington — Lexington, Kentucky, United States
Saint Joseph Radiation Oncology Resource Center — Lexington, Kentucky, United States
CommonSpirit Saint Joseph Medical Center - East Lexington — Lexington, Kentucky, United States
CommonSpirit Saint Joseph Hospital London — London, Kentucky, United States
Jewish Hospital — Louisville, Kentucky, United States
Saints Mary and Elizabeth Hospital — Louisville, Kentucky, United States
UofL Health Medical Center Northeast — Louisville, Kentucky, United States
CommonSpirit Saint Joseph Hospital Mount Sterling — Mount Sterling, Kentucky, United States
Jewish Hospital Medical Center South — Shepherdsville, Kentucky, United States
LSU Health Baton Rouge-North Clinic — Baton Rouge, Louisiana, United States
Our Lady of the Lake Physician Group — Baton Rouge, Louisiana, United States
Ochsner LSU Health Monroe Medical Center — Monroe, Louisiana, United States
LSU Health Sciences Center at Shreveport — Shreveport, Louisiana, United States
Christiana Care - Union Hospital — Elkton, Maryland, United States
Frederick Memorial Hospital — Frederick, Maryland, United States
FMH James M Stockman Cancer Institute — Frederick, Maryland, United States
Tufts Medical Center — Boston, Massachusetts, United States
Tufts Medical Center Cancer Center Stoneham — Stoneham, Massachusetts, United States
Hickman Cancer Center — Adrian, Michigan, United States
MyMichigan Medical Center Gratiot — Alma, Michigan, United States
MyMichigan Medical Center Alpena — Alpena, Michigan, United States
Trinity Health Saint Joseph Mercy Hospital Ann Arbor — Ann Arbor, Michigan, United States
Bronson Battle Creek — Battle Creek, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology - Brighton — Brighton, Michigan, United States
Trinity Health Medical Center - Brighton — Brighton, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology - Canton — Canton, Michigan, United States
Trinity Health Medical Center - Canton — Canton, Michigan, United States
Caro Cancer Center — Caro, Michigan, United States
Chelsea Hospital — Chelsea, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital — Chelsea, Michigan, United States
Hematology Oncology Consultants-Clarkston — Clarkston, Michigan, United States
Newland Medical Associates-Clarkston — Clarkston, Michigan, United States
Henry Ford Hospital — Detroit, Michigan, United States
Henry Ford Health Saint John Hospital — Detroit, Michigan, United States
Henry Ford River District Hospital — East China Township, Michigan, United States
OSF Saint Francis Hospital and Medical Group — Escanaba, Michigan, United States
Cancer Hematology Centers - Flint — Flint, Michigan, United States
Genesee Hematology Oncology PC — Flint, Michigan, United States
Genesys Hurley Cancer Institute — Flint, Michigan, United States
Hurley Medical Center — Flint, Michigan, United States
MyMichigan Medical Center Gladwin — Gladwin, Michigan, United States
Corewell Health Grand Rapids Hospitals - Butterworth Hospital — Grand Rapids, Michigan, United States
Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital — Grand Rapids, Michigan, United States
Trinity Health Grand Rapids Hospital — Grand Rapids, Michigan, United States
Henry Ford Saint John Hospital - Academic — Grosse Pointe Woods, Michigan, United States
Henry Ford Saint John Hospital - Breast — Grosse Pointe Woods, Michigan, United States
Henry Ford Saint John Hospital - Van Elslander — Grosse Pointe Woods, Michigan, United States
Bronson Methodist Hospital — Kalamazoo, Michigan, United States
West Michigan Cancer Center — Kalamazoo, Michigan, United States
Beacon Kalamazoo Cancer Center — Kalamazoo, Michigan, United States
Beacon Kalamazoo — Kalamazoo, Michigan, United States
University of Michigan Health - Sparrow Lansing — Lansing, Michigan, United States
Hope Cancer Clinic — Livonia, Michigan, United States
Trinity Health Saint Mary Mercy Livonia Hospital — Livonia, Michigan, United States
Henry Ford Saint John Hospital - Macomb Medical — Macomb, Michigan, United States
Henry Ford Warren Hospital - Breast Macomb — Macomb, Michigan, United States
Saint Mary's Oncology/Hematology Associates of Marlette — Marlette, Michigan, United States
MyMichigan Medical Center Midland — Midland, Michigan, United States
Toledo Clinic Cancer Centers-Monroe — Monroe, Michigan, United States
MyMichigan Medical Center Mount Pleasant — Mount Pleasant, Michigan, United States
Trinity Health Muskegon Hospital — Muskegon, Michigan, United States
Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan, United States
Cancer and Hematology Centers of Western Michigan - Norton Shores — Norton Shores, Michigan, United States
Henry Ford Health Providence Novi Hospital — Novi, Michigan, United States
Hope Cancer Center — Pontiac, Michigan, United States
Michigan Healthcare Professionals Pontiac — Pontiac, Michigan, United States
Newland Medical Associates-Pontiac — Pontiac, Michigan, United States
Trinity Health Saint Joseph Mercy Oakland Hospital — Pontiac, Michigan, United States
Corewell Health Reed City Hospital — Reed City, Michigan, United States
Henry Ford Rochester Hospital — Rochester Hills, Michigan, United States
MyMichigan Medical Center Saginaw — Saginaw, Michigan, United States
Oncology Hematology Associates of Saginaw Valley PC — Saginaw, Michigan, United States
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center — Saint Joseph, Michigan, United States
Corewell Health Lakeland Hospitals - Saint Joseph Hospital — Saint Joseph, Michigan, United States
Henry Ford Health Providence Southfield Hospital — Southfield, Michigan, United States
Bhadresh Nayak MD PC-Sterling Heights — Sterling Heights, Michigan, United States
MyMichigan Medical Center Tawas — Tawas City, Michigan, United States
Munson Medical Center — Traverse City, Michigan, United States
Advanced Breast Care Center PLLC — Warren, Michigan, United States
Henry Ford Health Warren Hospital — Warren, Michigan, United States
Henry Ford Madison Heights Hospital - Breast — Warren, Michigan, United States
Henry Ford Warren Hospital - GLCMS — Warren, Michigan, United States
Macomb Hematology Oncology PC — Warren, Michigan, United States
Saint Mary's Oncology/Hematology Associates of West Branch — West Branch, Michigan, United States
University of Michigan Health - West — Wyoming, Michigan, United States
Huron Gastroenterology PC — Ypsilanti, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus — Ypsilanti, Michigan, United States
Sanford Joe Lueken Cancer Center — Bemidji, Minnesota, United States
Fairview Ridges Hospital — Burnsville, Minnesota, United States
Minnesota Oncology - Burnsville — Burnsville, Minnesota, United States
Cambridge Medical Center — Cambridge, Minnesota, United States
Minnesota Oncology Hematology PA-Chaska — Chaska, Minnesota, United States
Mercy Hospital — Coon Rapids, Minnesota, United States
Minnesota Oncology - Coon Rapids — Coon Rapids, Minnesota, United States
Fairview Southdale Hospital — Edina, Minnesota, United States
Minnesota Oncology - Edina — Edina, Minnesota, United States
Unity Hospital — Fridley, Minnesota, United States
Fairview Clinics and Surgery Center Maple Grove — Maple Grove, Minnesota, United States
Minnesota Oncology - Maple Grove — Maple Grove, Minnesota, United States
Minnesota Oncology Hematology PA-Maplewood — Maplewood, Minnesota, United States
Saint John's Hospital - Healtheast — Maplewood, Minnesota, United States
Abbott-Northwestern Hospital — Minneapolis, Minnesota, United States
Hennepin County Medical Center — Minneapolis, Minnesota, United States
Health Partners Inc — Minneapolis, Minnesota, United States
Monticello Cancer Center — Monticello, Minnesota, United States
New Ulm Medical Center — New Ulm, Minnesota, United States
Fairview Northland Medical Center — Princeton, Minnesota, United States
North Memorial Medical Health Center — Robbinsdale, Minnesota, United States
Mayo Clinic in Rochester — Rochester, Minnesota, United States
Coborn Cancer Center at Saint Cloud Hospital — Saint Cloud, Minnesota, United States
Park Nicollet Clinic - Saint Louis Park — Saint Louis Park, Minnesota, United States
Regions Hospital — Saint Paul, Minnesota, United States
United Hospital — Saint Paul, Minnesota, United States
Saint Francis Regional Medical Center — Shakopee, Minnesota, United States
Lakeview Hospital — Stillwater, Minnesota, United States
Sanford Thief River Falls Medical Center — Thief River Falls, Minnesota, United States
Ridgeview Medical Center — Waconia, Minnesota, United States
Rice Memorial Hospital — Willmar, Minnesota, United States
Minnesota Oncology Hematology PA-Woodbury — Woodbury, Minnesota, United States
Fairview Lakes Medical Center — Wyoming, Minnesota, United States
Gulfport Memorial Hospital — Gulfport, Mississippi, United States
Mercy Oncology and Hematology - Clayton-Clarkson — Ballwin, Missouri, United States
Central Care Cancer Center - Bolivar — Bolivar, Missouri, United States
Cox Cancer Center Branson — Branson, Missouri, United States
Mercy Cancer Center - Cape Girardeau — Cape Girardeau, Missouri, United States
Saint Francis Medical Center — Cape Girardeau, Missouri, United States
Saint Luke's Hospital — Chesterfield, Missouri, United States
Parkland Health Center - Farmington — Farmington, Missouri, United States
MU Health Care Goldschmidt Cancer Center — Jefferson City, Missouri, United States
Freeman Health System — Joplin, Missouri, United States
Mercy Hospital Joplin — Joplin, Missouri, United States
Kansas City Veterans Affairs Medical Center — Kansas City, Missouri, United States
Lake Regional Hospital — Osage Beach, Missouri, United States
Mercy Clinic-Rolla-Cancer and Hematology — Rolla, Missouri, United States
Phelps Health Delbert Day Cancer Institute — Rolla, Missouri, United States
Heartland Regional Medical Center — Saint Joseph, Missouri, United States
Sainte Genevieve County Memorial Hospital — Sainte Genevieve, Missouri, United States
Mercy Hospital Springfield — Springfield, Missouri, United States
CoxHealth South Hospital — Springfield, Missouri, United States
Mercy Infusion Center - Chippewa — St Louis, Missouri, United States
Mercy Hospital South — St Louis, Missouri, United States
Missouri Baptist Medical Center — St Louis, Missouri, United States
Mercy Hospital Saint Louis — St Louis, Missouri, United States
Missouri Baptist Sullivan Hospital — Sullivan, Missouri, United States
Mercy Hospital Washington — Washington, Missouri, United States
Community Hospital of Anaconda — Anaconda, Montana, United States
Billings Clinic Cancer Center — Billings, Montana, United States
Bozeman Health Deaconess Hospital — Bozeman, Montana, United States
Benefis Sletten Cancer Institute — Great Falls, Montana, United States
Great Falls Clinic — Great Falls, Montana, United States
Hi-Line Sletten Cancer Center — Havre, Montana, United States
Benefis Helena Specialty Center — Helena, Montana, United States
Logan Health Medical Center — Kalispell, Montana, United States
Saint Patrick Hospital - Community Hospital — Missoula, Montana, United States
Community Medical Center — Missoula, Montana, United States
CHI Health Saint Francis — Grand Island, Nebraska, United States
Nebraska Cancer Specialists/Oncology Hematology West PC — Grand Island, Nebraska, United States
CHI Health Good Samaritan — Kearney, Nebraska, United States
Saint Elizabeth Regional Medical Center — Lincoln, Nebraska, United States
Cancer Partners of Nebraska — Lincoln, Nebraska, United States
Alegent Health Immanuel Medical Center — Omaha, Nebraska, United States
Alegent Health Bergan Mercy Medical Center — Omaha, Nebraska, United States
Alegent Health Lakeside Hospital — Omaha, Nebraska, United States
Midlands Community Hospital — Papillion, Nebraska, United States
Jefferson Cherry Hill Hospital — Cherry Hill, New Jersey, United States
Englewood Hospital and Medical Center — Englewood, New Jersey, United States
Morristown Medical Center — Morristown, New Jersey, United States
Sidney Kimmel Cancer Center Washington Township — Sewell, New Jersey, United States
Overlook Hospital — Summit, New Jersey, United States
University of New Mexico Cancer Center — Albuquerque, New Mexico, United States
Hematology Oncology Associates of Central New York-Auburn — Auburn, New York, United States
Lourdes Hospital — Binghamton, New York, United States
Hematology Oncology Associates of CNY at Camillus — Camillus, New York, United States
Hematology Oncology Associates of Central New York-East Syracuse — East Syracuse, New York, United States
Glens Falls Hospital — Glens Falls, New York, United States
University of Rochester — Rochester, New York, United States
Stony Brook University Medical Center — Stony Brook, New York, United States
State University of New York Upstate Medical University — Syracuse, New York, United States
Upstate Cancer Center at Verona — Verona, New York, United States
Good Samaritan University Hospital — West Islip, New York, United States
Southeastern Medical Oncology Center-Clinton — Clinton, North Carolina, United States
Southeastern Medical Oncology Center-Goldsboro — Goldsboro, North Carolina, United States
East Carolina University — Greenville, North Carolina, United States
Southeastern Medical Oncology Center-Jacksonville — Jacksonville, North Carolina, United States
ECU Health Oncology Kenansville — Kenansville, North Carolina, United States
ECU Health Oncology Kinston — Kinston, North Carolina, United States
ECU Health Oncology Richlands — Richlands, North Carolina, United States
Sanford Bismarck Medical Center — Bismarck, North Dakota, United States
Sanford South University Medical Center — Fargo, North Dakota, United States
Southpointe-Sanford Medical Center Fargo — Fargo, North Dakota, United States
Sanford Medical Center Fargo — Fargo, North Dakota, United States
Sanford Broadway Medical Center — Fargo, North Dakota, United States
Sanford Roger Maris Cancer Center — Fargo, North Dakota, United States
OhioHealth O'Bleness Hospital — Athens, Ohio, United States
UHHS-Chagrin Highlands Medical Center — Beachwood, Ohio, United States
Indu and Raj Soin Medical Center — Beavercreek, Ohio, United States
Strecker Cancer Center-Belpre — Belpre, Ohio, United States
Saint Elizabeth Boardman Hospital — Boardman, Ohio, United States
Dayton Physicians LLC-Miami Valley South — Centerville, Ohio, United States
Miami Valley Hospital South — Centerville, Ohio, United States
Geauga Hospital — Chardon, Ohio, United States
Adena Regional Medical Center — Chillicothe, Ohio, United States
University of Cincinnati Cancer Center-UC Medical Center — Cincinnati, Ohio, United States
Good Samaritan Hospital - Cincinnati — Cincinnati, Ohio, United States
Oncology Hematology Care Inc-Kenwood — Cincinnati, Ohio, United States
Bethesda North Hospital — Cincinnati, Ohio, United States
TriHealth Cancer Institute-Westside — Cincinnati, Ohio, United States
TriHealth Cancer Institute-Anderson — Cincinnati, Ohio, United States
Case Western Reserve University — Cleveland, Ohio, United States
Louis Stokes Cleveland VA Medical Center — Cleveland, Ohio, United States
MetroHealth Medical Center — Cleveland, Ohio, United States
Mount Carmel East Hospital — Columbus, Ohio, United States
Columbus Oncology and Hematology Associates Inc — Columbus, Ohio, United States
Riverside Methodist Hospital — Columbus, Ohio, United States
Grant Medical Center — Columbus, Ohio, United States
The Mark H Zangmeister Center — Columbus, Ohio, United States
Mount Carmel Health Center West — Columbus, Ohio, United States
Doctors Hospital — Columbus, Ohio, United States
Miami Valley Hospital — Dayton, Ohio, United States
Premier Blood and Cancer Center — Dayton, Ohio, United States
Dayton Physician LLC - Englewood — Dayton, Ohio, United States
Miami Valley Hospital North — Dayton, Ohio, United States
Delaware Health Center-Grady Cancer Center — Delaware, Ohio, United States
Grady Memorial Hospital — Delaware, Ohio, United States
Columbus Oncology and Hematology Associates — Dublin, Ohio, United States
Dublin Methodist Hospital — Dublin, Ohio, United States
Armes Family Cancer Center — Findlay, Ohio, United States
Blanchard Valley Hospital — Findlay, Ohio, United States
Orion Cancer Care — Findlay, Ohio, United States
Atrium Medical Center-Middletown Regional Hospital — Franklin, Ohio, United States
Dayton Physicians LLC-Atrium — Franklin, Ohio, United States
Central Ohio Breast and Endocrine Surgery — Gahanna, Ohio, United States
Dayton Physicians LLC-Wayne — Greenville, Ohio, United States
Miami Valley Cancer Care and Infusion — Greenville, Ohio, United States
Wayne Hospital — Greenville, Ohio, United States
Mount Carmel Grove City Hospital — Grove City, Ohio, United States
Zangmeister Center Grove City — Grove City, Ohio, United States
Greater Dayton Cancer Center — Kettering, Ohio, United States
Kettering Medical Center — Kettering, Ohio, United States
Fairfield Medical Center — Lancaster, Ohio, United States
Saint Rita's Medical Center — Lima, Ohio, United States
OhioHealth Mansfield Hospital — Mansfield, Ohio, United States
Marietta Memorial Hospital — Marietta, Ohio, United States
OhioHealth Marion General Hospital — Marion, Ohio, United States
Memorial Hospital — Marysville, Ohio, United States
Toledo Clinic Cancer Centers-Maumee — Maumee, Ohio, United States
UH Seidman Cancer Center at Landerbrook Health Center — Mayfield Heights, Ohio, United States
Knox Community Hospital — Mount Vernon, Ohio, United States
Mount Carmel New Albany Surgical Hospital — New Albany, Ohio, United States
Licking Memorial Hospital — Newark, Ohio, United States
Newark Radiation Oncology — Newark, Ohio, United States
University Hospitals Parma Medical Center — Parma, Ohio, United States
Mercy Health - Perrysburg Hospital — Perrysburg, Ohio, United States
OhioHealth Pickerington Methodist Hospital — Pickerington, Ohio, United States
Southern Ohio Medical Center — Portsmouth, Ohio, United States
Springfield Regional Cancer Center — Springfield, Ohio, United States
Springfield Regional Medical Center — Springfield, Ohio, United States
Mercy Health - Saint Vincent Hospital — Toledo, Ohio, United States
Mercy Health - Saint Anne Hospital — Toledo, Ohio, United States
Mercy Health Sylvania Radiation Oncology Center — Toledo, Ohio, United States
Toledo Clinic Cancer Centers-Toledo — Toledo, Ohio, United States
Dayton Physicians LLC - Troy — Troy, Ohio, United States
Upper Valley Medical Center — Troy, Ohio, United States
University Hospitals Sharon Health Center — Wadsworth, Ohio, United States
Saint Joseph Warren Hospital — Warren, Ohio, United States
University of Cincinnati Cancer Center-West Chester — West Chester, Ohio, United States
Saint Ann's Hospital — Westerville, Ohio, United States
OhioHealth Westerville Medical Campus/Westerville Cancer Center — Westerville, Ohio, United States
UH Seidman Cancer Center at Saint John Medical Center — Westlake, Ohio, United States
Clinton Memorial Hospital/Foster J Boyd Regional Cancer Center — Wilmington, Ohio, United States
Saint Elizabeth Youngstown Hospital — Youngstown, Ohio, United States
Genesis Healthcare System Cancer Care Center — Zanesville, Ohio, United States
Mercy Hospital Oklahoma City — Oklahoma City, Oklahoma, United States
Saint Alphonsus Cancer Care Center-Baker City — Baker City, Oregon, United States
Saint Charles Health System — Bend, Oregon, United States
Clackamas Radiation Oncology Center — Clackamas, Oregon, United States
Providence Cancer Institute Clackamas Clinic — Clackamas, Oregon, United States
Bay Area Hospital — Coos Bay, Oregon, United States
Providence Hood River Memorial Hospital — Hood River, Oregon, United States
Providence Newberg Medical Center — Newberg, Oregon, United States
Saint Alphonsus Cancer Care Center-Ontario — Ontario, Oregon, United States
Providence Willamette Falls Medical Center — Oregon City, Oregon, United States
Providence Portland Medical Center — Portland, Oregon, United States
Providence Saint Vincent Medical Center — Portland, Oregon, United States
Oregon Health and Science University — Portland, Oregon, United States
Saint Charles Health System-Redmond — Redmond, Oregon, United States
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania, United States
Lehigh Valley Hospital - Muhlenberg — Bethlehem, Pennsylvania, United States
Christiana Care Health System-Concord Health Center — Chadds Ford, Pennsylvania, United States
Geisinger Medical Center — Danville, Pennsylvania, United States
Geisinger Cancer Center Dickson City — Dickson City, Pennsylvania, United States
Pocono Medical Center — East Stroudsburg, Pennsylvania, United States
Penn State Health Medical Group - Andrews Patel Hematology/Oncology East — Harrisburg, Pennsylvania, United States
Geisinger Medical Center-Cancer Center Hazleton — Hazleton, Pennsylvania, United States
Lehigh Valley Hospital-Hazleton — Hazleton, Pennsylvania, United States
Penn State Milton S Hershey Medical Center — Hershey, Pennsylvania, United States
Geisinger Medical Oncology-Lewisburg — Lewisburg, Pennsylvania, United States
Thomas Jefferson University Hospital — Philadelphia, Pennsylvania, United States
Geisinger Cancer Services-Pottsville — Pottsville, Pennsylvania, United States
Penn State Health Saint Joseph Medical Center — Reading, Pennsylvania, United States
Community Medical Center — Scranton, Pennsylvania, United States
Reading Hospital — West Reading, Pennsylvania, United States
Geisinger Wyoming Valley/Henry Cancer Center — Wilkes-Barre, Pennsylvania, United States
Smilow Cancer Hospital Care Center - Westerly — Westerly, Rhode Island, United States
Ralph H Johnson VA Medical Center — Charleston, South Carolina, United States
Medical University of South Carolina — Charleston, South Carolina, United States
Saint Francis Hospital — Greenville, South Carolina, United States
Saint Francis Cancer Center — Greenville, South Carolina, United States
Rapid City Regional Hospital — Rapid City, South Dakota, United States
Avera Cancer Institute — Sioux Falls, South Dakota, United States
Vanderbilt University/Ingram Cancer Center — Nashville, Tennessee, United States
Saint Joseph Regional Cancer Center — Bryan, Texas, United States
Huntsman Cancer Institute/University of Utah — Salt Lake City, Utah, United States
University of Vermont Medical Center — Burlington, Vermont, United States
University of Vermont and State Agricultural College — Burlington, Vermont, United States
White River Junction Veteran Administration Medical Center — White River Junction, Vermont, United States
University of Virginia Cancer Center — Charlottesville, Virginia, United States
Inova Schar Cancer Institute — Fairfax, Virginia, United States
Inova Fairfax Hospital — Falls Church, Virginia, United States
Centra Alan B Pearson Regional Cancer Center — Lynchburg, Virginia, United States
Virginia Cancer Institute — Richmond, Virginia, United States
VCU Massey Comprehensive Cancer Center — Richmond, Virginia, United States
VCU Community Memorial Health Center — South Hill, Virginia, United States
Providence Regional Cancer System-Aberdeen — Aberdeen, Washington, United States
PeaceHealth Saint Joseph Medical Center — Bellingham, Washington, United States
Highline Medical Center-Main Campus — Burien, Washington, United States
Providence Regional Cancer System-Centralia — Centralia, Washington, United States
Swedish Cancer Institute-Edmonds — Edmonds, Washington, United States
Saint Elizabeth Hospital — Enumclaw, Washington, United States
Providence Regional Cancer Partnership — Everett, Washington, United States
Saint Francis Hospital — Federal Way, Washington, United States
Swedish Cancer Institute-Issaquah — Issaquah, Washington, United States
Kadlec Clinic Hematology and Oncology — Kennewick, Washington, United States
Providence Regional Cancer System-Lacey — Lacey, Washington, United States
Saint Clare Hospital — Lakewood, Washington, United States
PeaceHealth Saint John Medical Center — Longview, Washington, United States
Skagit Regional Health Cancer Care Center — Mount Vernon, Washington, United States
Harrison HealthPartners Hematology and Oncology-Poulsbo — Poulsbo, Washington, United States
Pacific Gynecology Specialists — Seattle, Washington, United States
Swedish Medical Center-Ballard Campus — Seattle, Washington, United States
Swedish Medical Center-Cherry Hill — Seattle, Washington, United States
Swedish Medical Center-First Hill — Seattle, Washington, United States
PeaceHealth United General Medical Center — Sedro-Woolley, Washington, United States
Providence Regional Cancer System-Shelton — Shelton, Washington, United States
Saint Joseph Medical Center Hematology and Oncology - Silverdale — Silverdale, Washington, United States
Cancer Care Northwest - Spokane South — Spokane, Washington, United States
Cancer Care Northwest-Valley — Spokane, Washington, United States
Cancer Care Northwest-North Spokane — Spokane, Washington, United States
Franciscan Research Center-Northwest Medical Plaza — Tacoma, Washington, United States
Northwest Medical Specialties PLLC — Tacoma, Washington, United States
PeaceHealth Southwest Medical Center — Vancouver, Washington, United States
Providence Saint Mary Regional Cancer Center — Walla Walla, Washington, United States
Providence Regional Cancer System-Yelm — Yelm, Washington, United States
West Virginia University Charleston Division — Charleston, West Virginia, United States
ThedaCare Regional Cancer Center — Appleton, Wisconsin, United States
Ascension Northeast Wisconsin-Saint Elizabeth Cancer Center-Appleton — Appleton, Wisconsin, United States
SSM Health Dean Medical Group - Baraboo — Baraboo, Wisconsin, United States
Ascension Southeast Wisconsin Hospital-Elmbrook Campus-Brookfield — Brookfield, Wisconsin, United States
Aurora Cancer Care-Southern Lakes VLCC — Burlington, Wisconsin, United States
Ascension Calumet Hospital-Chilton — Chilton, Wisconsin, United States
Marshfield Clinic-Chippewa Center — Chippewa Falls, Wisconsin, United States
Aurora Saint Luke's South Shore — Cudahy, Wisconsin, United States
HSHS Sacred Heart Hospital — Eau Claire, Wisconsin, United States
Marshfield Medical Center-EC Cancer Center — Eau Claire, Wisconsin, United States
Ascension Southeast Wisconsin Hospital - Franklin — Franklin, Wisconsin, United States
Reiman Cancer Center-Ascension Wisconsin Health Center-Rawson — Franklin, Wisconsin, United States
Aurora Health Care Germantown Health Center — Germantown, Wisconsin, United States
Aurora Cancer Care-Grafton — Grafton, Wisconsin, United States
Saint Vincent Hospital Cancer Center Green Bay — Green Bay, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Saint Mary's — Green Bay, Wisconsin, United States
Aurora BayCare Medical Center — Green Bay, Wisconsin, United States
SSM Health Dean Medical Group - Janesville — Janesville, Wisconsin, United States
University of Wisconsin Carbone Cancer Center - Johnson Creek — Johnson Creek, Wisconsin, United States
Aurora Cancer Care-Kenosha South — Kenosha, Wisconsin, United States
Gundersen Lutheran Medical Center — La Crosse, Wisconsin, United States
Mayo Clinic Health System-Franciscan Healthcare — La Crosse, Wisconsin, United States
Marshfield Medical Center - Ladysmith — Ladysmith, Wisconsin, United States
William S Middleton VA Medical Center — Madison, Wisconsin, United States
SSM Health Dean Medical Group - South Madison Campus — Madison, Wisconsin, United States
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center — Madison, Wisconsin, United States
University of Wisconsin Carbone Cancer Center - University Hospital — Madison, Wisconsin, United States
Aurora Bay Area Medical Group-Marinette — Marinette, Wisconsin, United States
Marshfield Medical Center-Marshfield — Marshfield, Wisconsin, United States
Ascension Columbia Saint Mary's Hospital-Ozaukee Campus-Mequon — Mequon, Wisconsin, United States
Aurora Cancer Care-Milwaukee — Milwaukee, Wisconsin, United States
Ascension Southeast Wisconsin Hospital-Saint Joseph-Milwaukee — Milwaukee, Wisconsin, United States
Ascension Columbia Saint Mary's Hospital-Milwaukee Campus — Milwaukee, Wisconsin, United States
Ascension Saint Francis Hospital-Milwaukee — Milwaukee, Wisconsin, United States
Aurora Saint Luke's Medical Center — Milwaukee, Wisconsin, United States
Aurora Sinai Medical Center — Milwaukee, Wisconsin, United States
Marshfield Medical Center - Minocqua — Minocqua, Wisconsin, United States
ProHealth D N Greenwald Center — Mukwonago, Wisconsin, United States
ThedaCare Regional Medical Center - Neenah — Neenah, Wisconsin, United States
Marshfield Medical Center - Neillsville — Neillsville, Wisconsin, United States
Cancer Center of Western Wisconsin — New Richmond, Wisconsin, United States
ProHealth Oconomowoc Memorial Hospital — Oconomowoc, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Oconto Falls — Oconto Falls, Wisconsin, United States
Ascension Northeast Wisconsin-Mercy Hospital-Oshkosh — Oshkosh, Wisconsin, United States
Vince Lombardi Cancer Clinic - Oshkosh — Oshkosh, Wisconsin, United States
Ascension All Saints Hospital-Spring Street-Racine — Racine, Wisconsin, United States
Aurora Cancer Care-Racine — Racine, Wisconsin, United States
Marshfield Medical Center-Rice Lake — Rice Lake, Wisconsin, United States
Vince Lombardi Cancer Clinic-Sheboygan — Sheboygan, Wisconsin, United States
Marshfield Medical Center-River Region at Stevens Point — Stevens Point, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Sturgeon Bay — Sturgeon Bay, Wisconsin, United States
Aurora Medical Center in Summit — Summit, Wisconsin, United States
Vince Lombardi Cancer Clinic-Two Rivers — Two Rivers, Wisconsin, United States
ProHealth Waukesha Memorial Hospital — Waukesha, Wisconsin, United States
UW Cancer Center at ProHealth Care — Waukesha, Wisconsin, United States
Marshfield Clinic-Wausau Center — Wausau, Wisconsin, United States
Ascension Southeast Wisconsin Hospital-Mayfair Road-Wauwatosa — Wauwatosa, Wisconsin, United States
Aurora Cancer Care-Milwaukee West — Wauwatosa, Wisconsin, United States
Aurora West Allis Medical Center — West Allis, Wisconsin, United States
Marshfield Medical Center - Weston — Weston, Wisconsin, United States
Marshfield Clinic - Wisconsin Rapids Center — Wisconsin Rapids, Wisconsin, United States
Memorial Hospital of Laramie County — Cheyenne, Wyoming, United States
Billings Clinic-Cody — Cody, Wyoming, United States
Welch Cancer Center — Sheridan, Wyoming, United States
Cancer Center-Metro Medical Center Bayamon — Bayamón, Puerto Rico
Puerto Rico Hematology Oncology Group — Bayamón, Puerto Rico
Doctors Cancer Center — Manati, Puerto Rico
San Juan Community Oncology Group — San Juan, Puerto Rico
Centro Comprensivo de Cancer de UPR — San Juan, Puerto Rico
PROncology — San Juan, Puerto Rico
San Juan City Hospital — San Juan, Puerto Rico

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