RECRUITING Phase 3 ClinicalTrials.gov

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

Sponsor: National Cancer Institute (NCI) • ClinicalTrials.gov ID: NCT04269902

Registry updated: 2026-10-20

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Description

This phase III trial compares early treatment with venetoclax and obinutuzumab versus delayed treatment with venetoclax and obinutuzumab in patients with newly diagnosed high-risk chronic lymphocytic leukemia or small lymphocytic lymphoma. Venetoclax is in a class of medications called B-cell lymphoma-2 (BCL-2) inhibitors. It may stop the growth of cancer cells by blocking Bcl-2, a protein needed for cancer cell survival. Immunotherapy with monoclonal antibodies, such as obinutuzumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Starting treatment with the venetoclax and obinutuzumab early (before patients have symptoms) may have better outcomes for patients with chronic lymphocytic leukemia or small lymphocytic lymphoma compared to starting treatment with the venetoclax and obinutuzumab after patients show symptoms.

Interventions

Biospecimen Collection (Procedure)
Undergo collection of blood samples
Bone Marrow Aspiration (Procedure)
Undergo bone marrow aspiration
Bone Marrow Biopsy (Procedure)
Undergo bone marrow biopsy
Computed Tomography (Procedure)
Undergo CT
Obinutuzumab (Biological)
Given IV
Questionnaire Administration (Other)
Ancillary studies
Venetoclax (Drug)
Given PO

Eligibility criteria

Inclusion Criteria: * Participants must have a confirmed diagnosis of chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) (collectively referred to as CLL throughout) according to the 2018 International Workshop on CLL. Participants must have been diagnosed within 18 months prior to registration * Participants must have CLL-International Prognostic Index (CLL-IPI) score \>= 4 and/or complex cytogenetics (defined as 3+ chromosomal abnormalities) * Cytogenetic AND/OR FISH analyses must be completed at a Clinical Laboratory Improvement Act (CLIA)-approved (or laboratories accredited under Accreditation Canada Diagnostics to conduct FISH analyses) laboratory within 18 months prior to registration. At minimum, FISH panel should use probes to detect for abnormalities in chromosomes 13q, 12, 11q, and 17p * TP53 gene mutation analysis performed at any CLIA-approved (or laboratories accredited under Accreditation Canada Diagnostics) lab (if completed) must be obtained within 18 months prior to registration. This sequencing test is distinct from FISH studies for del(17p) * Note: TP53 gene mutation analysis is recommended but not required if the participant meets disease-related study criteria via a combination of risk factors that totals a score of 4 on the CLL-IPI score and/or has complex cytogenetics completed * Immunoglobulin heavy chain locus variable (IgVH) gene mutation analysis performed at any CLIA-approved lab (or laboratories accredited under Accreditation Canada Diagnostics) must be obtained prior to registration (at any time prior to registration) * Serum beta-2 microglobulin level must be obtained within 28 days prior to registration * Participants must not meet any of the IWCLL specified criteria for active CLL therapy * Treatment with high dose corticosteroids and/or intravenous immunoglobulin for autoimmune complications of CLL must be complete at least 4 weeks prior to enrollment * Steroids used for treatment of conditions other than CLL/SLL must be at a dose of at most 20 mg/day of prednisone or equivalent corticosteroid at the time of registration * Prior therapy with anti CD20 monoclonal antibodies is not allowed * Participants must not have received or be currently receiving any prior CLL-directed therapy, including non-protocol-related therapy, anti-cancer immunotherapy, experimental therapy (with exception of agents approved for emergency access use for the prevention or treatment of coronavirus disease 2019 \[COVID-19\]), or radiotherapy * Participants must not be receiving or planning to receive any other investigational agents before completing protocol therapy * Participants must be \>= 18 years of age * Participants must have Eastern Cooperative Oncology Group (ECOG) performance status =\< 2 * Platelet count \>= 100,000/mm\^3 within 28 days prior to registration * Absolute neutrophil count (ANC) \>= 1,000/mm\^3 within 28 days prior to registration * Creatinine clearance \>= 30mL/min (by Cockcroft Gault) within 28 days prior to registration * Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) \< 3.0 x upper limit of normal (ULN) within 28 days prior to registration * Total bilirubin =\< 2.0 x ULN (or 5.0 x ULN if the participant has a history of Gilbert's disease), within 28 days prior to registration * Participants must be able to take oral medications * Human immunodeficiency virus (HIV)-infected participants on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial * Participants with history of malignancy are allowed providing the cancer has not required active treatment within 2 years prior to registration (hormonal therapy is permissible). The following exceptions are permissible: basal cell, squamous cell skin, or non-melanomatous skin cancer, in situ cervical cancer, superficial bladder cancer not treated with intravesical chemotherapy or Bacillus Calmette-Guerin (BCG) within 6 months, localized prostate cancer treated with surgical resection and/or radiation only or requiring no more than chronic hormonal therapy, or prostate cancer with Gleason score ≤ 6, or localized breast cancer treated with surgical resection and/or radiation only or requiring no more than chronic hormonal therapy * Participants must not have current, clinically significant gastrointestinal malabsorption, in the opinion of treating doctor * Participants must not have cirrhosis * Obinutuzumab has been associated with hepatitis reactivation. Participants must not have uncontrolled active infection with hepatitis B or C. Participants with latent hepatitis B infection must agree to take prophylaxis during and for 6 months following active protocol therapy with V-O. * Active infection with hepatitis B or C: * Active infection is defined as detectable hepatitis B deoxyribonucleic acid (DNA) or hepatitis C ribonucleic acid (RNA) by quantitative polymerase chain reaction (PCR). * Latent infection with hepatitis B: * Latent infection is defined as meeting all of the following criteria: * Hepatitis B surface antigen positive * Anti-hepatitis B total core antibody positive * Anti-hepatitis IgM core antibody undetectable * Hepatitis B PCR undetectable * Participants with latent hepatitis B infection must agree to take prophylaxis with anti-hepatitis agents during and for 6 months following active protocol therapy with V-O. * Participants who have received intravenous immunoglobulin (IVIG) therapy within 6 months who are hepatitis B core total antibody positive but PCR undetectable are not mandated to take prophylaxis * Participants must not have had major surgery within 30 days prior registration or minor surgery within 7 days prior to registration. Examples of major surgery include neurosurgical procedures, joint replacements, and surgeries that occur inside the thoracic or abdomino-pelvic cavities. Examples of minor surgery include dental surgery, insertion of a venous access device, skin biopsy, or aspiration of a joint. If a participant has had a bone marrow biopsy for diagnosis or evaluation of CLL, this will not exclude the participant from registration to the study. If there is a question about whether a surgery is major or minor, this should be discussed with the Study Chair * Participants must not have known bleeding disorders (e.g., von Willebrand's disease or hemophilia) * Participants must not have a history of stroke or intracranial hemorrhage within 6 months prior to enrollment * Participants must not require continued therapy with a strong inhibitor or inducer of CYP3A4/5, as venetoclax is extensively metabolized by CYP3A4/5 * Participants must not have uncontrolled autoimmune hemolytic anemia or idiopathic thrombocytopenia purpura * Participants must not have any currently active, clinically significant cardiovascular disease, such as uncontrolled arrhythmia or class 3 or 4 congestive heart failure as defined by the New York Heart Association Functional Classification * Participants must not have a history of myocardial infarction, unstable angina, or acute coronary syndrome within 6 months prior to enrollment * Participants must not be pregnant or nursing, as there are no safety data available for these drug regimens during pregnancy. Women/men of reproductive potential must have agreed to use an effective contraceptive method. A woman is considered to be of "reproductive potential" if she has had menses at any time in the preceding 12 consecutive months. In addition to routine contraceptive methods, "effective contraception" also includes heterosexual celibacy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) defined as a hysterectomy, bilateral oophorectomy or bilateral tubal ligation. However, if at any point a previously celibate participant chooses to become heterosexually active during the time period for use of contraceptive measures outlined in the protocol, he/she is responsible for beginning contraceptive measures * Participants must agree to have specimens submitted for translational medicine (MRD) as outlined * Participants must be offered the opportunity to participate in specimen banking for future research as outlined. * NOTE: With participant's consent, the site must follow through with specimen submission as outlined * Participants who are able to complete patient reported outcome (PRO) forms in English, Spanish, French, German, Russian or Mandarin must be offered the opportunity to participate in the quality of life assessments. (Those participants who are unable to read and write in English, Spanish, French, German, Russian or Mandarin may be registered to S1925 without contributing to the quality of life portion of the study.) * Participants must be informed of the investigational nature of this study and must sign and give written informed consent in accordance with institutional and federal guidelines * NOTE: As a part of the Oncology Patient Enrollment Network (OPEN) registration process the treating institution's identity is provided in order to ensure that the current (within 365 days) date of institutional review board approval for this study has been entered in the system

Conditions

Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma

Locations

University of Alabama at Birmingham Cancer Center — Birmingham, Alabama, United States
Anchorage Associates in Radiation Medicine — Anchorage, Alaska, United States
Anchorage Radiation Therapy Center — Anchorage, Alaska, United States
Alaska Breast Care and Surgery LLC — Anchorage, Alaska, United States
Alaska Oncology and Hematology LLC — Anchorage, Alaska, United States
Alaska Women's Cancer Care — Anchorage, Alaska, United States
Anchorage Oncology Centre — Anchorage, Alaska, United States
Katmai Oncology Group — Anchorage, Alaska, United States
Providence Alaska Medical Center — Anchorage, Alaska, United States
Fairbanks Memorial Hospital — Fairbanks, Alaska, United States
Cancer Center at Saint Joseph's — Phoenix, Arizona, United States
Banner University Medical Center - Tucson — Tucson, Arizona, United States
University of Arizona Cancer Center-North Campus — Tucson, Arizona, United States
Mercy Hospital Fort Smith — Fort Smith, Arkansas, United States
CHI Saint Vincent Cancer Center Hot Springs — Hot Springs, Arkansas, United States
NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro — Jonesboro, Arkansas, United States
Kaiser Permanente-Anaheim — Anaheim, California, United States
Mission Hope Medical Oncology - Arroyo Grande — Arroyo Grande, California, United States
Kaiser Permanente-Baldwin Park — Baldwin Park, California, United States
Kaiser Permanente-Bellflower — Bellflower, California, United States
Providence Saint Joseph Medical Center/Disney Family Cancer Center — Burbank, California, United States
Marshall Cancer Center — Cameron Park, California, United States
Mercy Cancer Center - Carmichael — Carmichael, California, United States
Mercy San Juan Medical Center — Carmichael, California, United States
Enloe Medical Center — Chico, California, United States
UC Irvine Health Cancer Center-Newport — Costa Mesa, California, United States
City of Hope Comprehensive Cancer Center — Duarte, California, United States
Mercy Cancer Center - Elk Grove — Elk Grove, California, United States
Kaiser Permanente-Fontana — Fontana, California, United States
Kaiser Permanente South Bay — Harbor City, California, United States
City of Hope Seacliff — Huntington Beach, California, United States
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care — Irvine, California, United States
City of Hope at Irvine Lennar — Irvine, California, United States
Kaiser Permanente-Irvine — Irvine, California, United States
UCI Health Laguna Hills — Laguna Hills, California, United States
City of Hope Antelope Valley — Lancaster, California, United States
City of Hope at Long Beach Elm — Long Beach, California, United States
Tibor Rubin VA Medical Center — Long Beach, California, United States
Kaiser Permanente Los Angeles Medical Center — Los Angeles, California, United States
Kaiser Permanente West Los Angeles — Los Angeles, California, United States
Fremont - Rideout Cancer Center — Marysville, California, United States
City of Hope Newport Beach — Newport Beach, California, United States
Kaiser Permanente-Ontario — Ontario, California, United States
UC Irvine Health/Chao Family Comprehensive Cancer Center — Orange, California, United States
Stanford Cancer Institute Palo Alto — Palo Alto, California, United States
Kaiser Permanente - Panorama City — Panorama City, California, United States
Kaiser Permanente-Riverside — Riverside, California, United States
Mercy Cancer Center - Rocklin — Rocklin, California, United States
Mercy Cancer Center - Sacramento — Sacramento, California, United States
University of California Davis Comprehensive Cancer Center — Sacramento, California, United States
Kaiser Permanente-San Diego Zion — San Diego, California, United States
Pacific Central Coast Health Center-San Luis Obispo — San Luis Obispo, California, United States
Kaiser Permanente-San Marcos — San Marcos, California, United States
Mission Hope Medical Oncology - Santa Maria — Santa Maria, California, United States
City of Hope South Pasadena — South Pasadena, California, United States
City of Hope South Bay — Torrance, California, United States
City of Hope Upland — Upland, California, United States
Woodland Memorial Hospital — Woodland, California, United States
Kaiser Permanente-Woodland Hills — Woodland Hills, California, United States
Rocky Mountain Cancer Centers-Aurora — Aurora, Colorado, United States
The Medical Center of Aurora — Aurora, Colorado, United States
Boulder Community Foothills Hospital — Boulder, Colorado, United States
Rocky Mountain Cancer Centers-Boulder — Boulder, Colorado, United States
Rocky Mountain Cancer Centers - Centennial — Centennial, Colorado, United States
Penrose-Saint Francis Healthcare — Colorado Springs, Colorado, United States
Rocky Mountain Cancer Centers-Penrose — Colorado Springs, Colorado, United States
Cancer Center of Colorado at Sloan's Lake — Denver, Colorado, United States
National Jewish Health-Main Campus — Denver, Colorado, United States
The Women's Imaging Center — Denver, Colorado, United States
AdventHealth Porter — Denver, Colorado, United States
Colorado Blood Cancer Institute — Denver, Colorado, United States
Presbyterian - Saint Lukes Medical Center - Health One — Denver, Colorado, United States
Rocky Mountain Cancer Centers-Midtown — Denver, Colorado, United States
Saint Joseph Hospital - Cancer Centers of Colorado — Denver, Colorado, United States
Rocky Mountain Cancer Centers-Rose — Denver, Colorado, United States
Rose Medical Center — Denver, Colorado, United States
Western Surgical Care — Denver, Colorado, United States
CommonSpirit Cancer Center Mercy — Durango, Colorado, United States
Mercy Medical Center — Durango, Colorado, United States
Mountain Blue Cancer Care Center - Swedish — Englewood, Colorado, United States
Rocky Mountain Cancer Centers - Swedish — Englewood, Colorado, United States
Swedish Medical Center — Englewood, Colorado, United States
The Melanoma and Skin Cancer Institute — Englewood, Colorado, United States
National Jewish Health-Western Hematology Oncology — Golden, Colorado, United States
Saint Mary's Hospital and Regional Medical Center — Grand Junction, Colorado, United States
Grand Valley Oncology — Grand Junction, Colorado, United States
Banner North Colorado Medical Center — Greeley, Colorado, United States
Good Samaritan Hospital - Cancer Centers of Colorado — Lafayette, Colorado, United States
CommonSpirit Saint Anthony Hospital Cancer Center — Lakewood, Colorado, United States
Rocky Mountain Cancer Centers-Lakewood — Lakewood, Colorado, United States
Rocky Mountain Cancer Centers-Littleton — Littleton, Colorado, United States
AdventHealth Littleton — Littleton, Colorado, United States
Rocky Mountain Cancer Centers-Sky Ridge — Lone Tree, Colorado, United States
Sky Ridge Medical Center — Lone Tree, Colorado, United States
Longmont United Hospital — Longmont, Colorado, United States
Rocky Mountain Cancer Centers-Longmont — Longmont, Colorado, United States
Banner North Colorado Medical Center - Loveland Campus — Loveland, Colorado, United States
AdventHealth Parker — Parker, Colorado, United States
Saint Mary Corwin Medical Center — Pueblo, Colorado, United States
National Jewish Health-Northern Hematology Oncology — Thornton, Colorado, United States
Rocky Mountain Cancer Centers-Thornton — Thornton, Colorado, United States
Beebe Medical Center — Lewes, Delaware, United States
Beebe South Coastal Health Campus — Millville, Delaware, United States
Delaware Clinical and Laboratory Physicians PA — Newark, Delaware, United States
Helen F Graham Cancer Center — Newark, Delaware, United States
Medical Oncology Hematology Consultants PA — Newark, Delaware, United States
Christiana Care Health System-Christiana Hospital — Newark, Delaware, United States
Beebe Health Campus — Rehoboth Beach, Delaware, United States
TidalHealth Nanticoke / Allen Cancer Center — Seaford, Delaware, United States
Christiana Care Health System-Wilmington Hospital — Wilmington, Delaware, United States
MedStar Georgetown University Hospital — Washington D.C., District of Columbia, United States
Sibley Memorial Hospital — Washington D.C., District of Columbia, United States
Holy Cross Hospital — Fort Lauderdale, Florida, United States
Sacred Heart Hospital — Pensacola, Florida, United States
Saint Alphonsus Cancer Care Center-Boise — Boise, Idaho, United States
Saint Luke's Cancer Institute - Boise — Boise, Idaho, United States
Saint Alphonsus Cancer Care Center-Caldwell — Caldwell, Idaho, United States
Kootenai Health - Coeur d'Alene — Coeur d'Alene, Idaho, United States
Walter Knox Memorial Hospital — Emmett, Idaho, United States
Saint Luke's Cancer Institute - Fruitland — Fruitland, Idaho, United States
Idaho Urologic Institute-Meridian — Meridian, Idaho, United States
Saint Luke's Cancer Institute - Meridian — Meridian, Idaho, United States
Saint Alphonsus Cancer Care Center-Nampa — Nampa, Idaho, United States
Saint Luke's Cancer Institute - Nampa — Nampa, Idaho, United States
Kootenai Clinic Cancer Services - Post Falls — Post Falls, Idaho, United States
Kootenai Clinic Cancer Services - Sandpoint — Sandpoint, Idaho, United States
Saint Luke's Cancer Institute - Twin Falls — Twin Falls, Idaho, United States
OSF Saint Anthony's Health Center — Alton, Illinois, United States
Rush-Copley Medical Center — Aurora, Illinois, United States
Illinois CancerCare-Bloomington — Bloomington, Illinois, United States
Loyola Center for Health at Burr Ridge — Burr Ridge, Illinois, United States
Illinois CancerCare-Canton — Canton, Illinois, United States
Memorial Hospital of Carbondale — Carbondale, Illinois, United States
SIH Cancer Institute — Carterville, Illinois, United States
Illinois CancerCare-Carthage — Carthage, Illinois, United States
Centralia Oncology Clinic — Centralia, Illinois, United States
Northwestern University — Chicago, Illinois, United States
University of Chicago Comprehensive Cancer Center — Chicago, Illinois, United States
Carle at The Riverfront — Danville, Illinois, United States
Cancer Care Specialists of Illinois - Decatur — Decatur, Illinois, United States
Decatur Memorial Hospital — Decatur, Illinois, United States
Northwestern Medicine Cancer Center Kishwaukee — DeKalb, Illinois, United States
Illinois CancerCare-Dixon — Dixon, Illinois, United States
Carle Physician Group-Effingham — Effingham, Illinois, United States
Crossroads Cancer Center — Effingham, Illinois, United States
Elmhurst Memorial Hospital — Elmhurst, Illinois, United States
Illinois CancerCare-Eureka — Eureka, Illinois, United States
NorthShore University HealthSystem-Evanston Hospital — Evanston, Illinois, United States
Illinois CancerCare-Galesburg — Galesburg, Illinois, United States
Western Illinois Cancer Treatment Center — Galesburg, Illinois, United States
Northwestern Medicine Cancer Center Delnor — Geneva, Illinois, United States
NorthShore University HealthSystem-Glenbrook Hospital — Glenview, Illinois, United States
Northwestern Medicine Glenview Outpatient Center — Glenview, Illinois, United States
Northwestern Medicine Grayslake Outpatient Center — Grayslake, Illinois, United States
Ingalls Memorial Hospital — Harvey, Illinois, United States
NorthShore University HealthSystem-Highland Park Hospital — Highland Park, Illinois, United States
Loyola Medicine Homer Glen — Homer Glen, Illinois, United States
Illinois CancerCare-Kewanee Clinic — Kewanee, Illinois, United States
Northwestern Medicine Lake Forest Hospital — Lake Forest, Illinois, United States
Illinois CancerCare-Macomb — Macomb, Illinois, United States
Carle Physician Group-Mattoon/Charleston — Mattoon, Illinois, United States
Loyola University Medical Center — Maywood, Illinois, United States
Marjorie Weinberg Cancer Center at Loyola-Gottlieb — Melrose Park, Illinois, United States
SSM Health Good Samaritan — Mount Vernon, Illinois, United States
Edward Hospital/Cancer Center — Naperville, Illinois, United States
UC Comprehensive Cancer Center at Silver Cross — New Lenox, Illinois, United States
Cancer Care Center of O'Fallon — O'Fallon, Illinois, United States
University of Chicago Medicine-Orland Park — Orland Park, Illinois, United States
Illinois CancerCare-Ottawa Clinic — Ottawa, Illinois, United States
Illinois CancerCare-Pekin — Pekin, Illinois, United States
Illinois CancerCare-Peoria — Peoria, Illinois, United States
Methodist Medical Center of Illinois — Peoria, Illinois, United States
Illinois CancerCare-Peru — Peru, Illinois, United States
Valley Radiation Oncology — Peru, Illinois, United States
Edward Hospital/Cancer Center?Plainfield — Plainfield, Illinois, United States
Illinois CancerCare-Princeton — Princeton, Illinois, United States
UW Health Carbone Cancer Center Rockford — Rockford, Illinois, United States
Southern Illinois University School of Medicine — Springfield, Illinois, United States
Springfield Clinic — Springfield, Illinois, United States
Springfield Memorial Hospital — Springfield, Illinois, United States
Carle Cancer Center — Urbana, Illinois, United States
The Carle Foundation Hospital — Urbana, Illinois, United States
Northwestern Medicine Cancer Center Warrenville — Warrenville, Illinois, United States
Illinois CancerCare - Washington — Washington, Illinois, United States
Rush-Copley Healthcare Center — Yorkville, Illinois, United States
UChicago Medicine Northwest Indiana — Crown Point, Indiana, United States
Indiana University/Melvin and Bren Simon Cancer Center — Indianapolis, Indiana, United States
Reid Health — Richmond, Indiana, United States
Mary Greeley Medical Center — Ames, Iowa, United States
McFarland Clinic - Ames — Ames, Iowa, United States
UI Health Care Mission Cancer and Blood - Ankeny Clinic — Ankeny, Iowa, United States
McFarland Clinic - Boone — Boone, Iowa, United States
Saint Anthony Regional Hospital — Carroll, Iowa, United States
Physicians' Clinic of Iowa PC — Cedar Rapids, Iowa, United States
Mercy Cancer Center-West Lakes — Clive, Iowa, United States
UI Health Care Mission Cancer and Blood - West Des Moines Clinic — Clive, Iowa, United States
Alegent Health Mercy Hospital — Council Bluffs, Iowa, United States
Greater Regional Medical Center — Creston, Iowa, United States
Iowa Methodist Medical Center — Des Moines, Iowa, United States
UI Health Care Mission Cancer and Blood - Des Moines Clinic — Des Moines, Iowa, United States
Broadlawns Medical Center — Des Moines, Iowa, United States
Mercy Medical Center - Des Moines — Des Moines, Iowa, United States
UI Health Care Mission Cancer and Blood - Laurel Clinic — Des Moines, Iowa, United States
Iowa Lutheran Hospital — Des Moines, Iowa, United States
McFarland Clinic - Trinity Cancer Center — Fort Dodge, Iowa, United States
UI Healthcare Mission Cancer and Blood - Fort Dodge — Fort Dodge, Iowa, United States
McFarland Clinic - Jefferson — Jefferson, Iowa, United States
McFarland Clinic - Marshalltown — Marshalltown, Iowa, United States
UI Health Care Mission Cancer and Blood - Waukee Clinic — Waukee, Iowa, United States
Methodist West Hospital — West Des Moines, Iowa, United States
Mercy Medical Center-West Lakes — West Des Moines, Iowa, United States
Central Care Cancer Center - Garden City — Garden City, Kansas, United States
Central Care Cancer Center - Great Bend — Great Bend, Kansas, United States
HaysMed — Hays, Kansas, United States
University of Kansas Cancer Center — Kansas City, Kansas, United States
Lawrence Memorial Hospital — Lawrence, Kansas, United States
The University of Kansas Cancer Center - Olathe — Olathe, Kansas, United States
University of Kansas Cancer Center-Overland Park — Overland Park, Kansas, United States
Salina Regional Health Center — Salina, Kansas, United States
University of Kansas Health System Saint Francis Campus — Topeka, Kansas, United States
University of Kansas Hospital-Westwood Cancer Center — Westwood, Kansas, United States
CommonSpirit Saint Joseph Hospital - Bardstown — Bardstown, Kentucky, United States
Commonwealth Cancer Center-Corbin — Corbin, Kentucky, United States
Saint Joseph Radiation Oncology Resource Center — Lexington, Kentucky, United States
CommonSpirit Saint Joseph Medical Center - East Lexington — Lexington, Kentucky, United States
CommonSpirit Saint Joseph Hospital London — London, Kentucky, United States
Jewish Hospital — Louisville, Kentucky, United States
Saints Mary and Elizabeth Hospital — Louisville, Kentucky, United States
UofL Health Medical Center Northeast — Louisville, Kentucky, United States
Jewish Hospital Medical Center South — Shepherdsville, Kentucky, United States
Hematology/Oncology Clinic PLLC — Baton Rouge, Louisiana, United States
Ochsner LSU Health Monroe Medical Center — Monroe, Louisiana, United States
Tulane University School of Medicine — New Orleans, Louisiana, United States
Ochsner LSU Health Saint Mary's Medical Center — Shreveport, Louisiana, United States
LSU Health Sciences Center at Shreveport — Shreveport, Louisiana, United States
Harold Alfond Center for Cancer Care — Augusta, Maine, United States
MaineHealth Cancer Care and IV Therapy - Brunswick — Brunswick, Maine, United States
Mid Coast Hospital — Brunswick, Maine, United States
MaineHealth LincolnHealth Hospital — Damariscotta, Maine, United States
MaineHealth Maine Medical Center - Portland — Portland, Maine, United States
MaineHealth Maine Medical Center- Scarborough — Scarborough, Maine, United States
MaineHealth Cancer Care and IV Therapy - South Portland — South Portland, Maine, United States
Johns Hopkins University/Sidney Kimmel Cancer Center — Baltimore, Maryland, United States
Walter Reed National Military Medical Center — Bethesda, Maryland, United States
Tufts Medical Center — Boston, Massachusetts, United States
Dana-Farber Cancer Institute — Boston, Massachusetts, United States
Tufts Medical Center Cancer Center Stoneham — Stoneham, Massachusetts, United States
Hickman Cancer Center — Adrian, Michigan, United States
Trinity Health Saint Joseph Mercy Hospital Ann Arbor — Ann Arbor, Michigan, United States
Bronson Battle Creek — Battle Creek, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology - Brighton — Brighton, Michigan, United States
Trinity Health Medical Center - Brighton — Brighton, Michigan, United States
Henry Ford Cancer Institute-Downriver — Brownstown, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology - Canton — Canton, Michigan, United States
Trinity Health Medical Center - Canton — Canton, Michigan, United States
Caro Cancer Center — Caro, Michigan, United States
Chelsea Hospital — Chelsea, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital — Chelsea, Michigan, United States
Hematology Oncology Consultants-Clarkston — Clarkston, Michigan, United States
Newland Medical Associates-Clarkston — Clarkston, Michigan, United States
Henry Ford Macomb Hospital-Clinton Township — Clinton Township, Michigan, United States
Henry Ford Medical Center-Fairlane — Dearborn, Michigan, United States
Henry Ford Hospital — Detroit, Michigan, United States
Henry Ford Health Saint John Hospital — Detroit, Michigan, United States
Henry Ford River District Hospital — East China Township, Michigan, United States
Cancer Hematology Centers - Flint — Flint, Michigan, United States
Genesee Hematology Oncology PC — Flint, Michigan, United States
Genesys Hurley Cancer Institute — Flint, Michigan, United States
Hurley Medical Center — Flint, Michigan, United States
Corewell Health Grand Rapids Hospitals - Butterworth Hospital — Grand Rapids, Michigan, United States
Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital — Grand Rapids, Michigan, United States
Trinity Health Grand Rapids Hospital — Grand Rapids, Michigan, United States
Henry Ford Saint John Hospital - Academic — Grosse Pointe Woods, Michigan, United States
Henry Ford Saint John Hospital - Breast — Grosse Pointe Woods, Michigan, United States
Henry Ford Saint John Hospital - Van Elslander — Grosse Pointe Woods, Michigan, United States
Allegiance Health — Jackson, Michigan, United States
Bronson Methodist Hospital — Kalamazoo, Michigan, United States
West Michigan Cancer Center — Kalamazoo, Michigan, United States
Beacon Kalamazoo Cancer Center — Kalamazoo, Michigan, United States
Beacon Kalamazoo — Kalamazoo, Michigan, United States
University of Michigan Health - Sparrow Lansing — Lansing, Michigan, United States
Hope Cancer Clinic — Livonia, Michigan, United States
Trinity Health Saint Mary Mercy Livonia Hospital — Livonia, Michigan, United States
Henry Ford Saint John Hospital - Macomb Medical — Macomb, Michigan, United States
Henry Ford Warren Hospital - Breast Macomb — Macomb, Michigan, United States
Saint Mary's Oncology/Hematology Associates of Marlette — Marlette, Michigan, United States
Toledo Clinic Cancer Centers-Monroe — Monroe, Michigan, United States
Trinity Health Muskegon Hospital — Muskegon, Michigan, United States
Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan, United States
Cancer and Hematology Centers of Western Michigan - Norton Shores — Norton Shores, Michigan, United States
Henry Ford Health Providence Novi Hospital — Novi, Michigan, United States
Henry Ford Medical Center-Columbus — Novi, Michigan, United States
Hope Cancer Center — Pontiac, Michigan, United States
Michigan Healthcare Professionals Pontiac — Pontiac, Michigan, United States
Newland Medical Associates-Pontiac — Pontiac, Michigan, United States
Trinity Health Saint Joseph Mercy Oakland Hospital — Pontiac, Michigan, United States
Corewell Health Reed City Hospital — Reed City, Michigan, United States
MyMichigan Medical Center Saginaw — Saginaw, Michigan, United States
Oncology Hematology Associates of Saginaw Valley PC — Saginaw, Michigan, United States
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center — Saint Joseph, Michigan, United States
Corewell Health Lakeland Hospitals - Saint Joseph Hospital — Saint Joseph, Michigan, United States
Henry Ford Macomb Health Center - Shelby Township — Shelby, Michigan, United States
Henry Ford Health Providence Southfield Hospital — Southfield, Michigan, United States
Bhadresh Nayak MD PC-Sterling Heights — Sterling Heights, Michigan, United States
MyMichigan Medical Center Tawas — Tawas City, Michigan, United States
Munson Medical Center — Traverse City, Michigan, United States
Advanced Breast Care Center PLLC — Warren, Michigan, United States
Henry Ford Health Warren Hospital — Warren, Michigan, United States
Henry Ford Madison Heights Hospital - Breast — Warren, Michigan, United States
Henry Ford Warren Hospital - GLCMS — Warren, Michigan, United States
Macomb Hematology Oncology PC — Warren, Michigan, United States
Henry Ford West Bloomfield Hospital — West Bloomfield, Michigan, United States
Saint Mary's Oncology/Hematology Associates of West Branch — West Branch, Michigan, United States
Henry Ford Wyandotte Hospital — Wyandotte, Michigan, United States
University of Michigan Health - West — Wyoming, Michigan, United States
Huron Gastroenterology PC — Ypsilanti, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus — Ypsilanti, Michigan, United States
Fairview Ridges Hospital — Burnsville, Minnesota, United States
Minnesota Oncology - Burnsville — Burnsville, Minnesota, United States
Cambridge Medical Center — Cambridge, Minnesota, United States
Mercy Hospital — Coon Rapids, Minnesota, United States
Essentia Health - Deer River Clinic — Deer River, Minnesota, United States
Essentia Health Cancer Center — Duluth, Minnesota, United States
Fairview Southdale Hospital — Edina, Minnesota, United States
Unity Hospital — Fridley, Minnesota, United States
Essentia Health Hibbing Clinic — Hibbing, Minnesota, United States
Fairview Clinics and Surgery Center Maple Grove — Maple Grove, Minnesota, United States
Minnesota Oncology Hematology PA-Maplewood — Maplewood, Minnesota, United States
Saint John's Hospital - Healtheast — Maplewood, Minnesota, United States
Abbott-Northwestern Hospital — Minneapolis, Minnesota, United States
Hennepin County Medical Center — Minneapolis, Minnesota, United States
Minneapolis VA Medical Center — Minneapolis, Minnesota, United States
Health Partners Inc — Minneapolis, Minnesota, United States
Monticello Cancer Center — Monticello, Minnesota, United States
New Ulm Medical Center — New Ulm, Minnesota, United States
Fairview Northland Medical Center — Princeton, Minnesota, United States
North Memorial Medical Health Center — Robbinsdale, Minnesota, United States
Coborn Cancer Center at Saint Cloud Hospital — Saint Cloud, Minnesota, United States
Park Nicollet Clinic - Saint Louis Park — Saint Louis Park, Minnesota, United States
Regions Hospital — Saint Paul, Minnesota, United States
United Hospital — Saint Paul, Minnesota, United States
Essentia Health Sandstone — Sandstone, Minnesota, United States
Saint Francis Regional Medical Center — Shakopee, Minnesota, United States
Lakeview Hospital — Stillwater, Minnesota, United States
Essentia Health Virginia Clinic — Virginia, Minnesota, United States
Ridgeview Medical Center — Waconia, Minnesota, United States
Rice Memorial Hospital — Willmar, Minnesota, United States
Minnesota Oncology Hematology PA-Woodbury — Woodbury, Minnesota, United States
Fairview Lakes Medical Center — Wyoming, Minnesota, United States
Baptist Memorial Hospital and Cancer Center-Golden Triangle — Columbus, Mississippi, United States
Baptist Cancer Center-Grenada — Grenada, Mississippi, United States
Baptist Memorial Hospital and Cancer Center-Union County — New Albany, Mississippi, United States
Baptist Memorial Hospital and Cancer Center-Oxford — Oxford, Mississippi, United States
Baptist Memorial Hospital and Cancer Center-Desoto — Southhaven, Mississippi, United States
Mercy Oncology and Hematology - Clayton-Clarkson — Ballwin, Missouri, United States
Central Care Cancer Center - Bolivar — Bolivar, Missouri, United States
Mercy Cancer Center - Cape Girardeau — Cape Girardeau, Missouri, United States
Saint Francis Medical Center — Cape Girardeau, Missouri, United States
Saint Luke's Hospital — Chesterfield, Missouri, United States
Siteman Cancer Center at Saint Peters Hospital — City of Saint Peters, Missouri, United States
Siteman Cancer Center at West County Hospital — Creve Coeur, Missouri, United States
Parkland Health Center - Farmington — Farmington, Missouri, United States
MU Health Care Goldschmidt Cancer Center — Jefferson City, Missouri, United States
Freeman Health System — Joplin, Missouri, United States
Mercy Hospital Joplin — Joplin, Missouri, United States
University Health Truman Medical Center — Kansas City, Missouri, United States
University of Kansas Cancer Center - Briarcliff — Kansas City, Missouri, United States
Kansas City Veterans Affairs Medical Center — Kansas City, Missouri, United States
University of Kansas Cancer Center - North — Kansas City, Missouri, United States
University of Kansas Cancer Center - Lee's Summit — Lee's Summit, Missouri, United States
Mercy Clinic-Rolla-Cancer and Hematology — Rolla, Missouri, United States
Phelps Health Delbert Day Cancer Institute — Rolla, Missouri, United States
Heartland Regional Medical Center — Saint Joseph, Missouri, United States
Sainte Genevieve County Memorial Hospital — Sainte Genevieve, Missouri, United States
Mercy Hospital Springfield — Springfield, Missouri, United States
CoxHealth South Hospital — Springfield, Missouri, United States
Mercy Infusion Center - Chippewa — St Louis, Missouri, United States
Washington University School of Medicine — St Louis, Missouri, United States
Mercy Hospital South — St Louis, Missouri, United States
Siteman Cancer Center-South County — St Louis, Missouri, United States
Missouri Baptist Medical Center — St Louis, Missouri, United States
Siteman Cancer Center at Christian Hospital — St Louis, Missouri, United States
Mercy Hospital Saint Louis — St Louis, Missouri, United States
Missouri Baptist Sullivan Hospital — Sullivan, Missouri, United States
Mercy Hospital Washington — Washington, Missouri, United States
Community Hospital of Anaconda — Anaconda, Montana, United States
Billings Clinic Cancer Center — Billings, Montana, United States
Saint Vincent Healthcare — Billings, Montana, United States
Saint Vincent Frontier Cancer Center — Billings, Montana, United States
Bozeman Health Deaconess Hospital — Bozeman, Montana, United States
Benefis Sletten Cancer Institute — Great Falls, Montana, United States
Great Falls Clinic — Great Falls, Montana, United States
Logan Health Medical Center — Kalispell, Montana, United States
Saint Patrick Hospital - Community Hospital — Missoula, Montana, United States
Community Medical Center — Missoula, Montana, United States
Nebraska Cancer Specialists/Oncology Hematology West PC — Grand Island, Nebraska, United States
CHI Health Good Samaritan — Kearney, Nebraska, United States
Saint Elizabeth Regional Medical Center — Lincoln, Nebraska, United States
Cancer Partners of Nebraska — Lincoln, Nebraska, United States
Alegent Health Immanuel Medical Center — Omaha, Nebraska, United States
Alegent Health Bergan Mercy Medical Center — Omaha, Nebraska, United States
Alegent Health Lakeside Hospital — Omaha, Nebraska, United States
Midlands Community Hospital — Papillion, Nebraska, United States
OptumCare Cancer Care at Charleston — Las Vegas, Nevada, United States
OptumCare Cancer Care at Fort Apache — Las Vegas, Nevada, United States
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center — Lebanon, New Hampshire, United States
Memorial Sloan Kettering Basking Ridge — Basking Ridge, New Jersey, United States
Cooper Hospital University Medical Center — Camden, New Jersey, United States
Jersey City Medical Center — Jersey City, New Jersey, United States
Monmouth Medical Center Southern Campus — Lakewood, New Jersey, United States
Monmouth Medical Center — Long Branch, New Jersey, United States
Memorial Sloan Kettering Monmouth — Middletown, New Jersey, United States
Memorial Sloan Kettering Bergen — Montvale, New Jersey, United States
Rutgers Cancer Institute of New Jersey — New Brunswick, New Jersey, United States
Community Medical Center — Toms River, New Jersey, United States
MD Anderson Cancer Center at Cooper-Voorhees — Voorhees Township, New Jersey, United States
University of New Mexico Cancer Center — Albuquerque, New Mexico, United States
Presbyterian Kaseman Hospital — Albuquerque, New Mexico, United States
Memorial Medical Center-Las Cruces — Las Cruces, New Mexico, United States
Presbyterian Rust Medical Center/Jorgensen Cancer Center — Rio Rancho, New Mexico, United States
Hematology Oncology Associates of Central New York-Auburn — Auburn, New York, United States
Hematology Oncology Associates of CNY at Camillus — Camillus, New York, United States
Memorial Sloan Kettering Commack — Commack, New York, United States
Hematology Oncology Associates of Central New York-East Syracuse — East Syracuse, New York, United States
Glens Falls Hospital — Glens Falls, New York, United States
Memorial Sloan Kettering Westchester — Harrison, New York, United States
Mount Sinai Hospital — New York, New York, United States
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center — New York, New York, United States
Memorial Sloan Kettering Cancer Center — New York, New York, United States
Upstate Cancer Center at Oswego — Oswego, New York, United States
Rochester General Hospital — Rochester, New York, United States
University of Rochester — Rochester, New York, United States
State University of New York Upstate Medical University — Syracuse, New York, United States
SUNY Upstate Medical Center-Community Campus — Syracuse, New York, United States
Memorial Sloan Kettering Nassau — Uniondale, New York, United States
Upstate Cancer Center at Verona — Verona, New York, United States
Wilmot Cancer Institute at Webster — Webster, New York, United States
UNC Lineberger Comprehensive Cancer Center — Chapel Hill, North Carolina, United States
Southeastern Medical Oncology Center-Clinton — Clinton, North Carolina, United States
Durham VA Medical Center — Durham, North Carolina, United States
Duke University Medical Center — Durham, North Carolina, United States
Southeastern Medical Oncology Center-Goldsboro — Goldsboro, North Carolina, United States
East Carolina University — Greenville, North Carolina, United States
Margaret R Pardee Memorial Hospital — Hendersonville, North Carolina, United States
University of North Carolina-Hillsborough Campus — Hillsborough, North Carolina, United States
Southeastern Medical Oncology Center-Jacksonville — Jacksonville, North Carolina, United States
ECU Health Oncology Kenansville — Kenansville, North Carolina, United States
ECU Health Oncology Kinston — Kinston, North Carolina, United States
ECU Health Oncology Richlands — Richlands, North Carolina, United States
Indu and Raj Soin Medical Center — Beavercreek, Ohio, United States
Strecker Cancer Center-Belpre — Belpre, Ohio, United States
Saint Elizabeth Boardman Hospital — Boardman, Ohio, United States
Cleveland Clinic Mercy Hospital — Canton, Ohio, United States
Dayton Physicians LLC-Miami Valley South — Centerville, Ohio, United States
Miami Valley Hospital South — Centerville, Ohio, United States
Adena Regional Medical Center — Chillicothe, Ohio, United States
University of Cincinnati Cancer Center-UC Medical Center — Cincinnati, Ohio, United States
Good Samaritan Hospital - Cincinnati — Cincinnati, Ohio, United States
Oncology Hematology Care Inc-Kenwood — Cincinnati, Ohio, United States
Bethesda North Hospital — Cincinnati, Ohio, United States
TriHealth Cancer Institute-Westside — Cincinnati, Ohio, United States
TriHealth Cancer Institute-Anderson — Cincinnati, Ohio, United States
Cleveland Clinic Cancer Center/Fairview Hospital — Cleveland, Ohio, United States
Cleveland Clinic Foundation — Cleveland, Ohio, United States
Ohio State University Comprehensive Cancer Center — Columbus, Ohio, United States
Mount Carmel East Hospital — Columbus, Ohio, United States
Columbus Oncology and Hematology Associates Inc — Columbus, Ohio, United States
Riverside Methodist Hospital — Columbus, Ohio, United States
Grant Medical Center — Columbus, Ohio, United States
The Mark H Zangmeister Center — Columbus, Ohio, United States
Mount Carmel Health Center West — Columbus, Ohio, United States
Doctors Hospital — Columbus, Ohio, United States
Miami Valley Hospital — Dayton, Ohio, United States
Dayton Physician LLC - Englewood — Dayton, Ohio, United States
Miami Valley Hospital North — Dayton, Ohio, United States
Delaware Health Center-Grady Cancer Center — Delaware, Ohio, United States
Grady Memorial Hospital — Delaware, Ohio, United States
Dublin Methodist Hospital — Dublin, Ohio, United States
Armes Family Cancer Center — Findlay, Ohio, United States
Blanchard Valley Hospital — Findlay, Ohio, United States
Orion Cancer Care — Findlay, Ohio, United States
Atrium Medical Center-Middletown Regional Hospital — Franklin, Ohio, United States
Dayton Physicians LLC-Atrium — Franklin, Ohio, United States
Central Ohio Breast and Endocrine Surgery — Gahanna, Ohio, United States
Dayton Physicians LLC-Wayne — Greenville, Ohio, United States
Wayne Hospital — Greenville, Ohio, United States
Mount Carmel Grove City Hospital — Grove City, Ohio, United States
Greater Dayton Cancer Center — Kettering, Ohio, United States
Kettering Medical Center — Kettering, Ohio, United States
Fairfield Medical Center — Lancaster, Ohio, United States
Saint Rita's Medical Center — Lima, Ohio, United States
OhioHealth Mansfield Hospital — Mansfield, Ohio, United States
Marietta Memorial Hospital — Marietta, Ohio, United States
OhioHealth Marion General Hospital — Marion, Ohio, United States
Memorial Hospital — Marysville, Ohio, United States
Hillcrest Hospital Cancer Center — Mayfield Heights, Ohio, United States
Knox Community Hospital — Mount Vernon, Ohio, United States
Licking Memorial Hospital — Newark, Ohio, United States
Newark Radiation Oncology — Newark, Ohio, United States
Mercy Health - Perrysburg Hospital — Perrysburg, Ohio, United States
Southern Ohio Medical Center — Portsmouth, Ohio, United States
Springfield Regional Cancer Center — Springfield, Ohio, United States
Springfield Regional Medical Center — Springfield, Ohio, United States
ProMedica Flower Hospital — Sylvania, Ohio, United States
Mercy Health - Saint Vincent Hospital — Toledo, Ohio, United States
Mercy Health - Saint Anne Hospital — Toledo, Ohio, United States
Toledo Clinic Cancer Centers-Toledo — Toledo, Ohio, United States
Dayton Physicians LLC - Troy — Troy, Ohio, United States
Upper Valley Medical Center — Troy, Ohio, United States
Saint Joseph Warren Hospital — Warren, Ohio, United States
University of Cincinnati Cancer Center-West Chester — West Chester, Ohio, United States
Saint Ann's Hospital — Westerville, Ohio, United States
Wright-Patterson Medical Center — Wright-Patterson Air Force Base, Ohio, United States
Saint Elizabeth Youngstown Hospital — Youngstown, Ohio, United States
Genesis Healthcare System Cancer Care Center — Zanesville, Ohio, United States
University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma, United States
Mercy Hospital Oklahoma City — Oklahoma City, Oklahoma, United States
Saint Alphonsus Cancer Care Center-Baker City — Baker City, Oregon, United States
Saint Charles Health System — Bend, Oregon, United States
Clackamas Radiation Oncology Center — Clackamas, Oregon, United States
Providence Cancer Institute Clackamas Clinic — Clackamas, Oregon, United States
Bay Area Hospital — Coos Bay, Oregon, United States
Providence Newberg Medical Center — Newberg, Oregon, United States
Saint Alphonsus Cancer Care Center-Ontario — Ontario, Oregon, United States
Providence Willamette Falls Medical Center — Oregon City, Oregon, United States
Providence Portland Medical Center — Portland, Oregon, United States
Providence Saint Vincent Medical Center — Portland, Oregon, United States
Saint Charles Health System-Redmond — Redmond, Oregon, United States
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania, United States
Lehigh Valley Hospital - Muhlenberg — Bethlehem, Pennsylvania, United States
Christiana Care Health System-Concord Health Center — Chadds Ford, Pennsylvania, United States
Geisinger Medical Center — Danville, Pennsylvania, United States
Pocono Medical Center — East Stroudsburg, Pennsylvania, United States
Lehigh Valley Hospital-Hazleton — Hazleton, Pennsylvania, United States
Thomas Jefferson University Hospital — Philadelphia, Pennsylvania, United States
Jefferson Torresdale Hospital — Philadelphia, Pennsylvania, United States
UPMC Hillman Cancer Center — Pittsburgh, Pennsylvania, United States
Geisinger Wyoming Valley/Henry Cancer Center — Wilkes-Barre, Pennsylvania, United States
Asplundh Cancer Pavilion — Willow Grove, Pennsylvania, United States
Prisma Health Cancer Institute - Spartanburg — Boiling Springs, South Carolina, United States
Ralph H Johnson VA Medical Center — Charleston, South Carolina, United States
Medical University of South Carolina — Charleston, South Carolina, United States
Prisma Health Cancer Institute - Easley — Easley, South Carolina, United States
Prisma Health Cancer Institute - Butternut — Greenville, South Carolina, United States
Prisma Health Cancer Institute - Faris — Greenville, South Carolina, United States
Prisma Health Cancer Institute - Eastside — Greenville, South Carolina, United States
Prisma Health Cancer Institute - Greer — Greer, South Carolina, United States
Prisma Health Cancer Institute - Seneca — Seneca, South Carolina, United States
Bristol Regional Medical Center — Bristol, Tennessee, United States
Baptist Memorial Hospital and Cancer Center-Collierville — Collierville, Tennessee, United States
Ballad Health Cancer Care - Kingsport — Kingsport, Tennessee, United States
Wellmont Holston Valley Hospital and Medical Center — Kingsport, Tennessee, United States
Baptist Memorial Hospital and Cancer Center-Memphis — Memphis, Tennessee, United States
Vanderbilt University/Ingram Cancer Center — Nashville, Tennessee, United States
Saint Joseph Regional Cancer Center — Bryan, Texas, United States
UT Southwestern/Simmons Cancer Center-Dallas — Dallas, Texas, United States
STCC at DHR Health Institute for Research and Development — Edinburg, Texas, United States
UT Southwestern Clinical Center at Richardson/Plano — Richardson, Texas, United States
Huntsman Cancer Institute/University of Utah — Salt Lake City, Utah, United States
Ballad Health Cancer Care - Bristol — Bristol, Virginia, United States
Ballad Health Cancer Care - Norton — Norton, Virginia, United States
VCU Massey Cancer Center at Stony Point — Richmond, Virginia, United States
VCU Massey Comprehensive Cancer Center — Richmond, Virginia, United States
Providence Regional Cancer System-Aberdeen — Aberdeen, Washington, United States
FHCC Overlake — Bellevue, Washington, United States
PeaceHealth Saint Joseph Medical Center — Bellingham, Washington, United States
Highline Medical Center-Main Campus — Burien, Washington, United States
Providence Regional Cancer System-Centralia — Centralia, Washington, United States
Swedish Cancer Institute-Edmonds — Edmonds, Washington, United States
Saint Elizabeth Hospital — Enumclaw, Washington, United States
Providence Regional Cancer Partnership — Everett, Washington, United States
Saint Francis Hospital — Federal Way, Washington, United States
Swedish Cancer Institute-Issaquah — Issaquah, Washington, United States
Kadlec Clinic Hematology and Oncology — Kennewick, Washington, United States
FHCC at EvergreenHealth — Kirkland, Washington, United States
Providence Regional Cancer System-Lacey — Lacey, Washington, United States
Saint Clare Hospital — Lakewood, Washington, United States
PeaceHealth Saint John Medical Center — Longview, Washington, United States
Jefferson Healthcare — Port Townsend, Washington, United States
Harrison HealthPartners Hematology and Oncology-Poulsbo — Poulsbo, Washington, United States
Pacific Gynecology Specialists — Seattle, Washington, United States
Swedish Medical Center-Ballard Campus — Seattle, Washington, United States
Fred Hutchinson Cancer Center — Seattle, Washington, United States
Swedish Medical Center-Cherry Hill — Seattle, Washington, United States
Swedish Medical Center-First Hill — Seattle, Washington, United States
FHCC at Northwest Hospital — Seattle, Washington, United States
University of Washington Medical Center - Montlake — Seattle, Washington, United States
PeaceHealth United General Medical Center — Sedro-Woolley, Washington, United States
Providence Regional Cancer System-Shelton — Shelton, Washington, United States
Saint Joseph Medical Center Hematology and Oncology - Silverdale — Silverdale, Washington, United States
Franciscan Research Center-Northwest Medical Plaza — Tacoma, Washington, United States
Northwest Medical Specialties PLLC — Tacoma, Washington, United States
PeaceHealth Southwest Medical Center — Vancouver, Washington, United States
Providence Saint Mary Regional Cancer Center — Walla Walla, Washington, United States
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital — Yakima, Washington, United States
Providence Regional Cancer System-Yelm — Yelm, Washington, United States
Aspirus Cancer Care-Antigo-Volm Cancer Center — Antigo, Wisconsin, United States
ThedaCare Regional Cancer Center — Appleton, Wisconsin, United States
Duluth Clinic Ashland — Ashland, Wisconsin, United States
HSHS Sacred Heart Hospital — Eau Claire, Wisconsin, United States
Marshfield Medical Center-EC Cancer Center — Eau Claire, Wisconsin, United States
Bellin Memorial Hospital — Green Bay, Wisconsin, United States
Saint Vincent Hospital Cancer Center Green Bay — Green Bay, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Saint Mary's — Green Bay, Wisconsin, United States
Gundersen Lutheran Medical Center — La Crosse, Wisconsin, United States
University of Wisconsin Carbone Cancer Center - Eastpark Medical Center — Madison, Wisconsin, United States
University of Wisconsin Carbone Cancer Center - University Hospital — Madison, Wisconsin, United States
Marshfield Medical Center-Marshfield — Marshfield, Wisconsin, United States
Aspirus Medford Hospital — Medford, Wisconsin, United States
Zablocki Veterans Administration Medical Center — Milwaukee, Wisconsin, United States
Marshfield Medical Center - Minocqua — Minocqua, Wisconsin, United States
Cancer Center of Western Wisconsin — New Richmond, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Oconto Falls — Oconto Falls, Wisconsin, United States
Aspirus Cancer Care-Rhinelander-James Beck Cancer Center — Rhinelander, Wisconsin, United States
Marshfield Medical Center-Rice Lake — Rice Lake, Wisconsin, United States
Saint Vincent Hospital Cancer Center at Sheboygan — Sheboygan, Wisconsin, United States
Aspirus Cancer Care - Stevens Point — Stevens Point, Wisconsin, United States
Marshfield Medical Center-River Region at Stevens Point — Stevens Point, Wisconsin, United States
Aspirus Cancer Care-Wausau — Wausau, Wisconsin, United States
Marshfield Medical Center - Weston — Weston, Wisconsin, United States
Aspirus Cancer Care - Wisconsin Rapids — Wisconsin Rapids, Wisconsin, United States
Cheyenne Regional Medical Center-West — Cheyenne, Wyoming, United States
Billings Clinic-Cody — Cody, Wyoming, United States
Welch Cancer Center — Sheridan, Wyoming, United States
BCCA-Vancouver Cancer Centre — Vancouver, British Columbia, Canada
CancerCare Manitoba — Winnipeg, Manitoba, Canada
Atlantic Health Sciences Corporation-Saint John Regional Hospital — Saint John, New Brunswick, Canada
QEII Health Sciences Centre/Nova Scotia Health Authority — Halifax, Nova Scotia, Canada
Lakeridge Health Oshawa — Oshawa, Ontario, Canada
Ottawa Hospital and Cancer Center-General Campus — Ottawa, Ontario, Canada
Jewish General Hospital — Montreal, Quebec, Canada
Allan Blair Cancer Centre — Regina, Saskatchewan, Canada

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