RECRUITING Phase 2 ClinicalTrials.gov

Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors

Sponsor: National Cancer Institute (NCI) • ClinicalTrials.gov ID: NCT03866382

Registry updated: 2026-10-19

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Description

This phase II trial studies how well cabozantinib works in combination with nivolumab and ipilimumab in treating patients with rare genitourinary (GU) tumors that has spread from where it first started (primary site) to other places in the body. Cabozantinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as nivolumab and ipilimumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Giving cabozantinib, nivolumab, and ipilimumab may work better in treating patients with genitourinary tumors that have no treatment options compared to giving cabozantinib, nivolumab, or ipilimumab alone.

Interventions

Biospecimen Collection (Procedure)
Undergo blood and urine sample collection
Bone Scan (Procedure)
Undergo bone scan
Cabozantinib S-malate (Drug)
Given PO
Computed Tomography (Procedure)
Undergo CT and/or PET/CT scan
Echocardiography Test (Procedure)
Undergo echocardiography
Ipilimumab (Biological)
Given IV
Magnetic Resonance Imaging (Procedure)
Undergo MRI
Nivolumab (Biological)
Given IV
Positron Emission Tomography (Procedure)
Undergo PET/CT scan

Eligibility criteria

Inclusion Criteria: * Metastatic disease defined as new or progressive lesions on cross-sectional imaging or bone scan. Patients must have at least: * One measurable site of disease as per Response Evaluation Criteria in Solid Tumors (RECIST) version (v) 1.1 * One bone lesion on bone scan (tec99 or sodium fluoride \[NaF\] PET/CT, CT or MRI) for the bone-only cohort. * Histologically confirmed diagnosis of one of the following metastatic cohorts: * Small cell/ neuroendocrine carcinoma of the bladder (Cohort A)- All urothelial carcinomas with any amount of neuroendocrine differentiation (including small cell differentiation) will be included. If the tumor is purely neuroendocrine, metastasis from another site of origin should be clinically excluded * Adenocarcinoma of the bladder, or urachal adenocarcinoma, or bladder/urethra clear cell adenocarcinoma (Cohort B) - must be pure (per World Health Organization \[WHO\] definition), (i.e. urothelial carcinoma with glandular differentiation is not considered a pure adenocarcinoma * Squamous cell carcinoma of the bladder (Cohort C) - must be pure (i.e. urothelial carcinoma with squamous differentiation is not considered a pure squamous cell carcinoma) * Plasmacytoid urothelial carcinoma (Cohort D) - Tumor should show predominantly \> or equal \~ 50% plasmacytoid histology (including all types of discohesive growth, such as tumors with signet-ring and/or rhabdoid features as well) * Any penile cancer (Cohort E) * Sarcomatoid renal cell carcinoma (Cohort F) - Tumor should be predominantly sarcomatoid \~ 50% (including rhabdoid differentiation) is also unclassified renal cell carcinomas (RCCs): all (assuming they are high grade with metastasis) malignant angiomyolipomas are allowed * Other miscellaneous histologic variants of the urothelial carcinoma, such as, but not limited to (Cohort G) : Micropapillary (Tumor should show predominantly \> or equal 50% micropapillary architecture), giant cell, lipid-rich, clear cell and nested variants (Tumor should predominantly \> or equal 50% show these features), large cell neuroendocrine carcinoma, lymphoepithelioma-like carcinoma and mixed patterns will be considered, as well as small cell neuroendocrine prostate cancer (Only treatment-naïve primary small cell of prostate with any amount of small cell component allowed. Post-treatment small cell prostatic carcinomas are not allowed), Malignant testicular Sertoli or Leydig cell tumors, and papillary and chromophobe RCC * Note: Translocation positive renal cell carcinoma patients are eligible. However, AREN1721 should be considered before this trial * Sarcomatoid urothelial carcinoma (Cohort H) - Tumor should show predominantly \~ 50% sarcomatoid differentiation * Renal medullary carcinoma (Cohort I) - Per World Health Organization (WHO) definition, ideally confirmed with immunostains * Bone-only metastatic GU tumors (non-prostate) (Cohort J) - All genitourinary histologies, except prostate are eligible * Renal Collecting Duct Carcinoma (Cohort K) - Per WHO definition (medullary involvement, predominant tubular morphology, desmoplastic stromal reaction, high grade cytology, infiltrative growth pattern, and absence of other renal cell carcinoma subtype or urothelial carcinoma) * Urethra carcinoma (Cohort L) - May be of any histology but if urothelial carcinoma then must be isolated to the urethra and not have metachronous or synchronous urothelial carcinoma of the bladder * H\&E slides from diagnostic tumor tissue for retrospective central pathology review * Patients may have received up to 2 systemic anti-cancer treatments or be treatment naive. Patients with small cell carcinoma should have received a platinum-based combination regimen either as neoadjuvant, adjuvant or first-line treatment). Patients in the bone-only cohort may be urothelial carcinoma histology but must receive standard cisplatin-based chemotherapy (if cisplatin-eligible) * Age \>= 18 years * Patients must be able to swallow oral formulation of the tablets * Karnofsky performance status \>= 80% * Absolute neutrophil count (ANC) \>= 1,000/mcL * Platelet count \>= 75,000/mcL * Total bilirubin =\< 1.5 x upper limit of normal (ULN). For subjects with known Gilbert's disease or similar syndrome with slow conjugation of bilirubin, total bilirubin =\< 3.0 mg/dL * Aspartate aminotransferase (AST)/alanine aminotransferase (ALT) =\< 3.0 x institutional upper limit of normal (ULN) (or =\< 5 x ULN for patients with liver metastases or Gilbert's disease) * Creatinine =\< 1.5 x upper limit of normal (ULN) OR creatinine clearance \>= 40 mL/min/1.73 m\^2 (calculated using the Chronic Kidney Disease Epidemiology \[CKD-EPI\] equation or Cockcroft-Gault formula) for patients with creatinine levels above institutional normal * Hemoglobin \>= 9 g/dL (transfusion of packed red blood cells \[PRBCs\] allowed) * Serum albumin \>= 3.2 g/dL * Lipase and amylase =\< 2.0 x ULN and no radiologic (on baseline anatomical imaging) or clinical evidence of pancreatitis * Prior treatment with MET or VEGFR inhibitors is allowed. However, prior cabozantinib will not be allowed. Also, patients that have received both prior MET or VEGF and prior PD-1/PD-L1/CTLA-4 (sequentially or in combination) are also not allowed * No prior treatment with any therapy on the PD-1/PD-L1 axis or anti- CTLA-4/CTLA-4 inhibitors with the exception of patients with "urothelial carcinoma" histology (cohorts D, H, J, L) * Human immunodeficiency virus (HIV)-positive patients are eligible if on stable dose of highly active antiretroviral therapy (HAART), no clinically significant drug-drug interactions are anticipated with the current HAART regimen, CD4 counts are greater than 350 and viral load is undetectable * Patients with rheumatoid arthritis and other rheumatologic arthropathies, Sjogren's syndrome and psoriasis controlled with topical medication only and patients with positive serology, such as antinuclear antibodies (ANA), anti-thyroid antibodies etc. are eligible but should be considered for rheumatologic evaluation for the presence of target organ involvement and potential need for systemic treatment * Patients with vitiligo, endocrine deficiencies including thyroiditis managed with replacement hormones or medications (e.g. thyroiditis managed with propylthiouracil \[PTU\] or methimazole) including physiologic oral corticosteroids are eligible * Patients who have evidence of active or acute diverticulitis, intra-abdominal abscess, and gastrointestinal (GI) obstruction, within 12 months are not eligible * Women of childbearing potential must have a negative pregnancy test =\< 7 days prior to registration * Women of childbearing potential include women who have experienced menarche and who have not undergone successful surgical sterilization (hysterectomy, bilateral tubal ligation, or bilateral oophorectomy) or are not postmenopausal. Post menopause is defined as amenorrhea \>= 12 consecutive months. Note: women who have been amenorrheic for 12 or more months are still considered to be of childbearing potential if the amenorrhea is possibly due to prior chemotherapy, antiestrogens, ovarian suppression or any other reversible reason * Pregnant women may not participate in this study because with cabozantinib, nivolumab, and ipilimumab have potential for teratogenic or abortifacient effects. Because there is an unknown but potential risk for adverse events in nursing infants secondary to treatment of the mother with cabozantinib, nivolumab, and ipilimumab, breastfeeding should be discontinued if the mother is treated with these agents * The patient has received no cytotoxic chemotherapy (including investigational cytotoxic chemotherapy) or biologic agents (e.g., cytokines or antibodies) within 2 weeks before the first dose of study treatment * The patient has received no radiation therapy: * To the lungs and mediastinum or abdomen within 4 weeks before the first dose of study treatment, or has ongoing complications, or is healing from prior radiation therapy * To brain metastasis within 3 weeks for whole-brain radiotherapy (WBXRT), and 2 weeks for stereotactic body radiation therapy (SBRT) before the first dose of study treatment * To the abdomen within 4 weeks before the first dose of study treatment, or has ongoing complications, or is healing from prior radiation therapy * To any other site(s) within 2 weeks before the first dose of study treatment * The patient has received no radionuclide treatment within 6 weeks of the first dose of study treatment * The patient has received no prior treatment with a small molecule kinase inhibitor within 14 days or five half-lives of the compound or active metabolites, whichever is longer, before the first dose of study treatment * The patient has received no prior treatment with hormonal therapy within 14 days or five half-lives of the compound or active metabolites, whichever is longer, before the first dose of study treatment. Subjects receiving gonadotropin-releasing hormone (GnRH) agonists and antagonists are allowed to participate * The patient has not received any other type of investigational agent within 14 days before the first dose of study treatment * The patient must have recovered to baseline or Common Terminology Criteria for Adverse Events (CTCAE) =\< grade 1 from toxicity due to all prior therapies except alopecia, neuropathy and other non-clinically significant adverse events (AEs) defined as lab elevation with no associated symptoms or sequelae * The patient may not have active brain metastases or epidural disease. Patients with brain metastases previously treated with whole brain radiation or radiosurgery who are asymptomatic and do not require steroid treatment for at least 2 weeks before starting study treatment are eligible. Neurosurgical resection of brain metastases or brain biopsy is permitted if completed at least 3 months before starting study treatment. Baseline brain imaging with contrast-enhanced CT or MRI scans for subjects with known brain metastases is required to confirm eligibility * No concomitant treatment with warfarin. Aspirin (up to 325 mg/day), thrombin or factor Xa inhibitors, low-dose warfarin (=\< 1 mg/day), prophylactic and therapeutic low molecular weight heparin (LMWH) are permitted * No chronic concomitant treatment with strong CYP3A4 inducers (e.g., dexamethasone, phenytoin, carbamazepine, rifampin, rifabutin, rifapentine, phenobarbital, and St. John's wort) or strong CYP3A4 inhibitors * Because the lists of these agents are constantly changing, it is important to regularly consult medical reference texts such as the Physicians' Desk Reference may also provide this information. As part of the enrollment/informed consent procedures, the patient will be counseled on the risk of interactions with other agents, and what to do if new medications need to be prescribed or if the patient is considering a new over-the-counter medicine or herbal product * The patient has not experienced any of the following: * Clinically-significant gastrointestinal bleeding within 6 months before the first dose of study treatment * Hemoptysis of \>= 0.5 teaspoon (2.5 mL) of red blood per day within 1 months before the first dose of study treatment * Any other signs indicative of pulmonary hemorrhage within 3 months before the first dose of study treatment * The patient has no tumor invading any major blood vessels * The patient has no evidence of tumor invading the GI tract (esophagus, stomach, small or large bowel, rectum or anus), or any evidence of endotracheal or endobronchial tumor within 28 days before the first dose of cabozantinib. Patients with rectal tumor masses are not eligible * The patient has no uncontrolled, significant intercurrent or recent illness including, but not limited to, the following conditions: * Cardiovascular disorders including: * Congestive heart failure (CHF): New York Heart Association (NYHA) class III (moderate) or class IV (severe) at the time of screening. * Concurrent uncontrolled hypertension defined as sustained blood pressure (BP) \> 150 mm Hg systolic, or \> 90 mm Hg diastolic despite optimal antihypertensive treatment within 7 days of the first dose of study treatment * The subject has a corrected QT interval calculated by the Fridericia formula (QTcF) \> 500 ms within 28 days before randomization. Note: if initial QTcF is found to be \> 500 ms, two additional electrocardiograms (EKGs) separated by at least 3 minutes should be performed. If the average of these three consecutive results for QTcF is =\< 500 ms, the subject meets eligibility in this regard * Any history of congenital long QT syndrome * Any of the following within 6 months before registration of study treatment: * Unstable angina pectoris * Clinically-significant cardiac arrhythmias (patients with atrial fibrillation are eligible) * Stroke (including transient ischemic attack \[TIA\], or other ischemic event) * Myocardial infarction * Cardiomyopathy * No significant gastrointestinal disorders particularly those associated with a high risk of perforation or fistula formation including: * Any of the following that have not resolved within 28 days before the first dose of study treatment: * Active peptic ulcer disease * Acute diverticulitis, cholecystitis, symptomatic cholangitis or appendicitis, or malabsorption syndrome * None of the following within 2 years before the first dose of study treatment: * Abdominal fistula or genitourinary fistula * Gastrointestinal perforation * Bowel obstruction or gastric outlet obstruction * Intra-abdominal abscess. Note: Complete resolution of an intra-abdominal abscess must be confirmed prior to initiating treatment with cabozantinib even if the abscess occurred more than 2 years before the first dose of study treatment * Disorders associated with a high risk of fistula formation including percutaneous endoscopic gastrostomy (PEG) tube placement are not eligible * No other clinically significant disorders such as: * Severe active infection requiring IV systemic treatment within 14 days before the first dose of study treatment * Serious non-healing wound/ulcer/bone fracture within 28 days before the first dose of study treatment * History of organ or allogeneic stem cell transplant * Concurrent uncompensated hypothyroidism or thyroid dysfunction within 7 days before the first dose of study treatment (for asymptomatic patients with an elevated thyroid-stimulating hormone \[TSH\], thyroid replacement may be initiated if clinically indicated without delaying the start of study treatment) * No history of major surgery as follows: * Major surgery within 3 months of the first dose of cabozantinib; however, if there were no wound healing complications, patients with rapidly growing aggressive cancers, may start as soon as 6 weeks if wound has completely healed post-surgery * Minor surgery within 1 month of the first dose of cabozantinib if there were no wound healing complications or within 3 months of the first dose of cabozantinib if there were wound complications excluding core biopsies and mediport placement * Complete wound healing from prior surgery must be confirmed before the first dose of cabozantinib irrespective of the time from surgery * No history of severe hypersensitivity reaction to any monoclonal antibody * No evidence of active malignancy, requiring systemic treatment within 2 years of registration * No history of allergic reactions attributed to compounds of similar chemical or biologic composition to cabozantinib, nivolumab, ipilimumab or other agents used in study * No positive test for hepatitis B virus surface antigen (HBV sAg) or hepatitis C virus ribonucleic acid (HCV antibody) indicating acute or chronic infection. If HBV sAG is positive, subsequent ribonucleic acid (RNA) polymerase chain reaction (PCR) must be negative * No patients with active autoimmune disease or history of autoimmune disease that might recur, which may affect vital organ function or require immune suppressive treatment including systemic corticosteroids. These include, but are not limited to patients with a history of immune related neurologic disease, multiple sclerosis, autoimmune (demyelinating) neuropathy, Guillain-Barre syndrome, myasthenia gravis; systemic autoimmune disease such as systemic lupus erythematosus (SLE), connective tissue diseases, scleroderma, inflammatory bowel disease (IBD), Crohn's, ulcerative colitis, hepatitis; and patients with a history of toxic epidermal necrolysis (TEN), Stevens-Johnson syndrome, or phospholipid syndrome should be excluded because of the risk of recurrence or exacerbation of disease

Conditions

Bladder Adenocarcinoma Bladder Clear Cell Adenocarcinoma Bladder Mixed Adenocarcinoma Bladder Neuroendocrine Carcinoma Bladder Small Cell Neuroendocrine Carcinoma Bladder Squamous Cell Carcinoma Chromophobe Renal Cell Carcinoma Collecting Duct Carcinoma Invasive Bladder Giant Cell Urothelial Carcinoma Invasive Bladder Lymphoepithelioma-Like Carcinoma Invasive Bladder Nested Urothelial Carcinoma Invasive Bladder Plasmacytoid Urothelial Carcinoma Invasive Bladder Sarcomatoid Urothelial Carcinoma Invasive Bladder Urothelial Carcinoma Kidney Medullary Carcinoma Large Cell Neuroendocrine Carcinoma Malignant Testicular Leydig Cell Tumor Malignant Testicular Sertoli Cell Tumor Metastatic Bladder Carcinoma Metastatic Bladder Clear Cell (Glycogen-Rich) Urothelial Carcinoma Metastatic Bladder Giant Cell Urothelial Carcinoma Metastatic Bladder Large Cell Neuroendocrine Carcinoma Metastatic Bladder Lipid-Rich Urothelial Carcinoma Metastatic Bladder Micropapillary Urothelial Carcinoma Metastatic Bladder Plasmacytoid Urothelial Carcinoma Metastatic Bladder Sarcomatoid Urothelial Carcinoma Metastatic Bladder Small Cell Neuroendocrine Carcinoma Metastatic Bladder Squamous Cell Carcinoma Metastatic Chromophobe Renal Cell Carcinoma Metastatic Kidney Medullary Carcinoma Metastatic Malignant Genitourinary System Neoplasm Metastatic Papillary Renal Cell Carcinoma Metastatic Penile Carcinoma Metastatic Prostate Small Cell Neuroendocrine Carcinoma Metastatic Sarcomatoid Renal Cell Carcinoma Metastatic Urethral Carcinoma Papillary Renal Cell Carcinoma Sarcomatoid Renal Cell Carcinoma Stage IV Bladder Cancer AJCC v8 Stage IV Penile Cancer AJCC v8 Stage IV Renal Cell Cancer AJCC v8 Stage IV Urethral Cancer AJCC v8 Stage IVB Prostate Cancer AJCC v8 Urachal Adenocarcinoma Urethral Clear Cell Adenocarcinoma

Locations

University of Alabama at Birmingham Cancer Center — Birmingham, Alabama, United States
Anchorage Associates in Radiation Medicine — Anchorage, Alaska, United States
Anchorage Radiation Therapy Center — Anchorage, Alaska, United States
Alaska Breast Care and Surgery LLC — Anchorage, Alaska, United States
Alaska Oncology and Hematology LLC — Anchorage, Alaska, United States
Alaska Women's Cancer Care — Anchorage, Alaska, United States
Anchorage Oncology Centre — Anchorage, Alaska, United States
Katmai Oncology Group — Anchorage, Alaska, United States
Providence Alaska Medical Center — Anchorage, Alaska, United States
Kingman Regional Medical Center — Kingman, Arizona, United States
Cancer Center at Saint Joseph's — Phoenix, Arizona, United States
Mayo Clinic Hospital in Arizona — Phoenix, Arizona, United States
Mayo Clinic in Arizona — Scottsdale, Arizona, United States
University of Arizona Cancer Center-Orange Grove Campus — Tucson, Arizona, United States
Banner University Medical Center - Tucson — Tucson, Arizona, United States
University of Arizona Cancer Center-North Campus — Tucson, Arizona, United States
Mercy Hospital Fort Smith — Fort Smith, Arkansas, United States
CHI Saint Vincent Cancer Center Hot Springs — Hot Springs, Arkansas, United States
Mission Hope Medical Oncology - Arroyo Grande — Arroyo Grande, California, United States
PCR Oncology — Arroyo Grande, California, United States
Providence Saint Joseph Medical Center/Disney Family Cancer Center — Burbank, California, United States
Community Cancer Institute — Clovis, California, United States
University Oncology Associates — Clovis, California, United States
Epic Care-Dublin — Dublin, California, United States
Bay Area Breast Surgeons Inc — Emeryville, California, United States
Epic Care Partners in Cancer Care — Emeryville, California, United States
Marin Cancer Care Inc — Greenbrae, California, United States
Keck Medicine of USC Koreatown — Los Angeles, California, United States
Los Angeles General Medical Center — Los Angeles, California, United States
USC / Norris Comprehensive Cancer Center — Los Angeles, California, United States
UCLA / Jonsson Comprehensive Cancer Center — Los Angeles, California, United States
Contra Costa Regional Medical Center — Martinez, California, United States
USC Norris Oncology/Hematology-Newport Beach — Newport Beach, California, United States
Alta Bates Summit Medical Center - Summit Campus — Oakland, California, United States
Bay Area Tumor Institute — Oakland, California, United States
Pacific Central Coast Health Center-San Luis Obispo — San Luis Obispo, California, United States
Mission Hope Medical Oncology - Santa Maria — Santa Maria, California, United States
Epic Care Cyberknife Center — Walnut Creek, California, United States
Penrose-Saint Francis Healthcare — Colorado Springs, Colorado, United States
Rocky Mountain Cancer Centers-Penrose — Colorado Springs, Colorado, United States
AdventHealth Porter — Denver, Colorado, United States
CommonSpirit Cancer Center Mercy — Durango, Colorado, United States
Mercy Medical Center — Durango, Colorado, United States
CommonSpirit Saint Anthony Hospital Cancer Center — Lakewood, Colorado, United States
AdventHealth Littleton — Littleton, Colorado, United States
Longmont United Hospital — Longmont, Colorado, United States
Rocky Mountain Cancer Centers-Longmont — Longmont, Colorado, United States
AdventHealth Parker — Parker, Colorado, United States
Saint Mary Corwin Medical Center — Pueblo, Colorado, United States
MedStar Georgetown University Hospital — Washington D.C., District of Columbia, United States
Mount Sinai Comprehensive Cancer Center at Aventura — Aventura, Florida, United States
Holy Cross Hospital — Fort Lauderdale, Florida, United States
Mount Sinai Medical Center — Miami Beach, Florida, United States
Orlando Health Cancer Institute — Orlando, Florida, United States
Emory University Hospital Midtown — Atlanta, Georgia, United States
Emory University Hospital/Winship Cancer Institute — Atlanta, Georgia, United States
Emory Saint Joseph's Hospital — Atlanta, Georgia, United States
Emory Johns Creek Hospital — Johns Creek, Georgia, United States
Saint Alphonsus Cancer Care Center-Boise — Boise, Idaho, United States
Saint Luke's Cancer Institute - Boise — Boise, Idaho, United States
Saint Alphonsus Cancer Care Center-Caldwell — Caldwell, Idaho, United States
Kootenai Health - Coeur d'Alene — Coeur d'Alene, Idaho, United States
Walter Knox Memorial Hospital — Emmett, Idaho, United States
Saint Luke's Cancer Institute - Fruitland — Fruitland, Idaho, United States
Idaho Urologic Institute-Meridian — Meridian, Idaho, United States
Saint Luke's Cancer Institute - Meridian — Meridian, Idaho, United States
Saint Alphonsus Cancer Care Center-Nampa — Nampa, Idaho, United States
Saint Luke's Cancer Institute - Nampa — Nampa, Idaho, United States
Kootenai Clinic Cancer Services - Post Falls — Post Falls, Idaho, United States
Kootenai Clinic Cancer Services - Sandpoint — Sandpoint, Idaho, United States
Saint Luke's Cancer Institute - Twin Falls — Twin Falls, Idaho, United States
OSF Saint Anthony's Health Center — Alton, Illinois, United States
Rush-Copley Medical Center — Aurora, Illinois, United States
Illinois CancerCare-Bloomington — Bloomington, Illinois, United States
Loyola Center for Health at Burr Ridge — Burr Ridge, Illinois, United States
Illinois CancerCare-Canton — Canton, Illinois, United States
Memorial Hospital of Carbondale — Carbondale, Illinois, United States
SIH Cancer Institute — Carterville, Illinois, United States
Illinois CancerCare-Carthage — Carthage, Illinois, United States
Northwestern University — Chicago, Illinois, United States
Rush MD Anderson Cancer Center — Chicago, Illinois, United States
University of Illinois — Chicago, Illinois, United States
University of Chicago Comprehensive Cancer Center — Chicago, Illinois, United States
Carle at The Riverfront — Danville, Illinois, United States
Cancer Care Specialists of Illinois - Decatur — Decatur, Illinois, United States
Decatur Memorial Hospital — Decatur, Illinois, United States
Illinois CancerCare-Dixon — Dixon, Illinois, United States
Carle Physician Group-Effingham — Effingham, Illinois, United States
Crossroads Cancer Center — Effingham, Illinois, United States
Illinois CancerCare-Eureka — Eureka, Illinois, United States
Illinois CancerCare-Galesburg — Galesburg, Illinois, United States
Western Illinois Cancer Treatment Center — Galesburg, Illinois, United States
Loyola Medicine Homer Glen — Homer Glen, Illinois, United States
Illinois CancerCare-Kewanee Clinic — Kewanee, Illinois, United States
Northwestern Medicine Lake Forest Hospital — Lake Forest, Illinois, United States
Illinois CancerCare-Macomb — Macomb, Illinois, United States
Carle Physician Group-Mattoon/Charleston — Mattoon, Illinois, United States
Loyola University Medical Center — Maywood, Illinois, United States
Marjorie Weinberg Cancer Center at Loyola-Gottlieb — Melrose Park, Illinois, United States
SSM Health Good Samaritan — Mount Vernon, Illinois, United States
UC Comprehensive Cancer Center at Silver Cross — New Lenox, Illinois, United States
Cancer Care Center of O'Fallon — O'Fallon, Illinois, United States
Rush MD Anderson Cancer Center at Rush Oak Park — Oak Park, Illinois, United States
University of Chicago Medicine-Orland Park — Orland Park, Illinois, United States
Illinois CancerCare-Ottawa Clinic — Ottawa, Illinois, United States
Illinois CancerCare-Pekin — Pekin, Illinois, United States
Illinois CancerCare-Peoria — Peoria, Illinois, United States
Methodist Medical Center of Illinois — Peoria, Illinois, United States
Illinois CancerCare-Peru — Peru, Illinois, United States
Valley Radiation Oncology — Peru, Illinois, United States
Illinois CancerCare-Princeton — Princeton, Illinois, United States
Memorial Hospital East — Shiloh, Illinois, United States
Southern Illinois University School of Medicine — Springfield, Illinois, United States
Springfield Clinic — Springfield, Illinois, United States
Springfield Memorial Hospital — Springfield, Illinois, United States
Southwest Illinois Health Services LLP — Swansea, Illinois, United States
Carle Cancer Center — Urbana, Illinois, United States
The Carle Foundation Hospital — Urbana, Illinois, United States
Illinois CancerCare - Washington — Washington, Illinois, United States
Rush-Copley Healthcare Center — Yorkville, Illinois, United States
Reid Health — Richmond, Indiana, United States
Mary Greeley Medical Center — Ames, Iowa, United States
McFarland Clinic - Ames — Ames, Iowa, United States
UI Health Care Mission Cancer and Blood - Ankeny Clinic — Ankeny, Iowa, United States
University of Iowa Healthcare Cancer Services Quad Cities — Bettendorf, Iowa, United States
McFarland Clinic - Boone — Boone, Iowa, United States
Mercy Cancer Center-West Lakes — Clive, Iowa, United States
UI Health Care Mission Cancer and Blood - West Des Moines Clinic — Clive, Iowa, United States
Alegent Health Mercy Hospital — Council Bluffs, Iowa, United States
Greater Regional Medical Center — Creston, Iowa, United States
Iowa Methodist Medical Center — Des Moines, Iowa, United States
UI Health Care Mission Cancer and Blood - Des Moines Clinic — Des Moines, Iowa, United States
Mercy Medical Center - Des Moines — Des Moines, Iowa, United States
UI Health Care Mission Cancer and Blood - Laurel Clinic — Des Moines, Iowa, United States
McFarland Clinic - Trinity Cancer Center — Fort Dodge, Iowa, United States
University of Iowa/Holden Comprehensive Cancer Center — Iowa City, Iowa, United States
McFarland Clinic - Jefferson — Jefferson, Iowa, United States
McFarland Clinic - Marshalltown — Marshalltown, Iowa, United States
UI Health Care Mission Cancer and Blood - Waukee Clinic — Waukee, Iowa, United States
Mercy Medical Center-West Lakes — West Des Moines, Iowa, United States
Cancer Center of Kansas - Chanute — Chanute, Kansas, United States
Cancer Center of Kansas - Dodge City — Dodge City, Kansas, United States
Cancer Center of Kansas - El Dorado — El Dorado, Kansas, United States
University of Kansas Clinical Research Center — Fairway, Kansas, United States
Central Care Cancer Center - Garden City — Garden City, Kansas, United States
Central Care Cancer Center - Great Bend — Great Bend, Kansas, United States
HaysMed — Hays, Kansas, United States
Cancer Center of Kansas-Independence — Independence, Kansas, United States
Cancer Center of Kansas-Kingman — Kingman, Kansas, United States
Lawrence Memorial Hospital — Lawrence, Kansas, United States
Cancer Center of Kansas-Liberal — Liberal, Kansas, United States
Cancer Center of Kansas-Manhattan — Manhattan, Kansas, United States
Cancer Center of Kansas - McPherson — McPherson, Kansas, United States
Cancer Center of Kansas - Newton — Newton, Kansas, United States
The University of Kansas Cancer Center - Olathe — Olathe, Kansas, United States
Cancer Center of Kansas - Parsons — Parsons, Kansas, United States
Freeman Physician Group of Pittsburg — Pittsburg, Kansas, United States
Mercy Hospital Pittsburg — Pittsburg, Kansas, United States
Cancer Center of Kansas - Pratt — Pratt, Kansas, United States
Cancer Center of Kansas - Salina — Salina, Kansas, United States
Salina Regional Health Center — Salina, Kansas, United States
University of Kansas Health System Saint Francis Campus — Topeka, Kansas, United States
Cancer Center of Kansas - Wellington — Wellington, Kansas, United States
University of Kansas Hospital-Westwood Cancer Center — Westwood, Kansas, United States
Cancer Center of Kansas-Wichita Medical Arts Tower — Wichita, Kansas, United States
Ascension Via Christi Hospitals Wichita — Wichita, Kansas, United States
Cancer Center of Kansas - Wichita — Wichita, Kansas, United States
Cancer Center of Kansas - Winfield — Winfield, Kansas, United States
CommonSpirit Saint Joseph Hospital - Bardstown — Bardstown, Kentucky, United States
Commonwealth Cancer Center-Corbin — Corbin, Kentucky, United States
Saint Joseph Radiation Oncology Resource Center — Lexington, Kentucky, United States
CommonSpirit Saint Joseph Medical Center - East Lexington — Lexington, Kentucky, United States
University of Kentucky/Markey Cancer Center — Lexington, Kentucky, United States
CommonSpirit Saint Joseph Hospital London — London, Kentucky, United States
Jewish Hospital — Louisville, Kentucky, United States
Saints Mary and Elizabeth Hospital — Louisville, Kentucky, United States
UofL Health Medical Center Northeast — Louisville, Kentucky, United States
Jewish Hospital Medical Center South — Shepherdsville, Kentucky, United States
Hematology/Oncology Clinic PLLC — Baton Rouge, Louisiana, United States
Louisiana Hematology Oncology Associates LLC — Baton Rouge, Louisiana, United States
Ochsner High Grove — Baton Rouge, Louisiana, United States
Northshore Oncology Associates-Covington — Covington, Louisiana, United States
Ochsner Medical Center Kenner — Kenner, Louisiana, United States
Mary Bird Perkins Cancer Center - Metairie — Metairie, Louisiana, United States
East Jefferson General Hospital — Metairie, Louisiana, United States
LSU Healthcare Network / Metairie Multi-Specialty Clinic — Metairie, Louisiana, United States
Louisiana State University Health Science Center — New Orleans, Louisiana, United States
Tulane University School of Medicine — New Orleans, Louisiana, United States
Ochsner Medical Center Jefferson — New Orleans, Louisiana, United States
Greater Baltimore Medical Center — Baltimore, Maryland, United States
National Institutes of Health Clinical Center — Bethesda, Maryland, United States
FMH James M Stockman Cancer Institute — Frederick, Maryland, United States
Lahey Clinic — Burlington, Massachusetts, United States
Lahey Clinic Peabody — Peabody, Massachusetts, United States
Mercy Medical Center — Springfield, Massachusetts, United States
Beth Israel Deaconess Medical Center/Winchester Center for Cancer Care — Winchester, Massachusetts, United States
Trinity Health Saint Joseph Mercy Hospital Ann Arbor — Ann Arbor, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology - Brighton — Brighton, Michigan, United States
Trinity Health Medical Center - Brighton — Brighton, Michigan, United States
Henry Ford Cancer Institute-Downriver — Brownstown, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology - Canton — Canton, Michigan, United States
Trinity Health Medical Center - Canton — Canton, Michigan, United States
Caro Cancer Center — Caro, Michigan, United States
Chelsea Hospital — Chelsea, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital — Chelsea, Michigan, United States
Hematology Oncology Consultants-Clarkston — Clarkston, Michigan, United States
Newland Medical Associates-Clarkston — Clarkston, Michigan, United States
Henry Ford Macomb Hospital-Clinton Township — Clinton Township, Michigan, United States
Henry Ford Medical Center-Fairlane — Dearborn, Michigan, United States
Henry Ford Hospital — Detroit, Michigan, United States
Henry Ford Health Saint John Hospital — Detroit, Michigan, United States
Henry Ford River District Hospital — East China Township, Michigan, United States
Cancer Hematology Centers - Flint — Flint, Michigan, United States
Genesee Hematology Oncology PC — Flint, Michigan, United States
Genesys Hurley Cancer Institute — Flint, Michigan, United States
Hurley Medical Center — Flint, Michigan, United States
Henry Ford Saint John Hospital - Academic — Grosse Pointe Woods, Michigan, United States
Henry Ford Saint John Hospital - Breast — Grosse Pointe Woods, Michigan, United States
Henry Ford Saint John Hospital - Van Elslander — Grosse Pointe Woods, Michigan, United States
Allegiance Health — Jackson, Michigan, United States
University of Michigan Health - Sparrow Lansing — Lansing, Michigan, United States
Hope Cancer Clinic — Livonia, Michigan, United States
Trinity Health Saint Mary Mercy Livonia Hospital — Livonia, Michigan, United States
Henry Ford Saint John Hospital - Macomb Medical — Macomb, Michigan, United States
Henry Ford Warren Hospital - Breast Macomb — Macomb, Michigan, United States
Saint Mary's Oncology/Hematology Associates of Marlette — Marlette, Michigan, United States
Henry Ford Medical Center-Columbus — Novi, Michigan, United States
Hope Cancer Center — Pontiac, Michigan, United States
Michigan Healthcare Professionals Pontiac — Pontiac, Michigan, United States
Newland Medical Associates-Pontiac — Pontiac, Michigan, United States
Trinity Health Saint Joseph Mercy Oakland Hospital — Pontiac, Michigan, United States
Huron Medical Center PC — Port Huron, Michigan, United States
Lake Huron Medical Center — Port Huron, Michigan, United States
Henry Ford Rochester Hospital — Rochester Hills, Michigan, United States
MyMichigan Medical Center Saginaw — Saginaw, Michigan, United States
Oncology Hematology Associates of Saginaw Valley PC — Saginaw, Michigan, United States
Henry Ford Macomb Health Center - Shelby Township — Shelby, Michigan, United States
Bhadresh Nayak MD PC-Sterling Heights — Sterling Heights, Michigan, United States
MyMichigan Medical Center Tawas — Tawas City, Michigan, United States
Advanced Breast Care Center PLLC — Warren, Michigan, United States
Henry Ford Health Warren Hospital — Warren, Michigan, United States
Henry Ford Madison Heights Hospital - Breast — Warren, Michigan, United States
Henry Ford Warren Hospital - GLCMS — Warren, Michigan, United States
Macomb Hematology Oncology PC — Warren, Michigan, United States
Henry Ford West Bloomfield Hospital — West Bloomfield, Michigan, United States
Saint Mary's Oncology/Hematology Associates of West Branch — West Branch, Michigan, United States
Henry Ford Wyandotte Hospital — Wyandotte, Michigan, United States
Huron Gastroenterology PC — Ypsilanti, Michigan, United States
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus — Ypsilanti, Michigan, United States
Riverwood Healthcare Center — Aitkin, Minnesota, United States
Essentia Health Saint Joseph's Medical Center — Brainerd, Minnesota, United States
Fairview Ridges Hospital — Burnsville, Minnesota, United States
Minnesota Oncology - Burnsville — Burnsville, Minnesota, United States
Cambridge Medical Center — Cambridge, Minnesota, United States
Mercy Hospital — Coon Rapids, Minnesota, United States
Essentia Health - Deer River Clinic — Deer River, Minnesota, United States
Essentia Health Saint Mary's - Detroit Lakes Clinic — Detroit Lakes, Minnesota, United States
Essentia Health Cancer Center — Duluth, Minnesota, United States
Essentia Health Saint Mary's Medical Center — Duluth, Minnesota, United States
Miller-Dwan Hospital — Duluth, Minnesota, United States
Fairview Southdale Hospital — Edina, Minnesota, United States
Lake Region Healthcare Corporation-Cancer Care — Fergus Falls, Minnesota, United States
Essentia Health - Fosston — Fosston, Minnesota, United States
Unity Hospital — Fridley, Minnesota, United States
Essentia Health Hibbing Clinic — Hibbing, Minnesota, United States
Fairview Clinics and Surgery Center Maple Grove — Maple Grove, Minnesota, United States
Minnesota Oncology Hematology PA-Maplewood — Maplewood, Minnesota, United States
Saint John's Hospital - Healtheast — Maplewood, Minnesota, United States
Abbott-Northwestern Hospital — Minneapolis, Minnesota, United States
Hennepin County Medical Center — Minneapolis, Minnesota, United States
Health Partners Inc — Minneapolis, Minnesota, United States
Monticello Cancer Center — Monticello, Minnesota, United States
New Ulm Medical Center — New Ulm, Minnesota, United States
Essentia Health - Park Rapids — Park Rapids, Minnesota, United States
Fairview Northland Medical Center — Princeton, Minnesota, United States
North Memorial Medical Health Center — Robbinsdale, Minnesota, United States
Mayo Clinic in Rochester — Rochester, Minnesota, United States
Park Nicollet Clinic - Saint Louis Park — Saint Louis Park, Minnesota, United States
Regions Hospital — Saint Paul, Minnesota, United States
United Hospital — Saint Paul, Minnesota, United States
Essentia Health Sandstone — Sandstone, Minnesota, United States
Saint Francis Regional Medical Center — Shakopee, Minnesota, United States
Lakeview Hospital — Stillwater, Minnesota, United States
Essentia Health Virginia Clinic — Virginia, Minnesota, United States
Ridgeview Medical Center — Waconia, Minnesota, United States
Rice Memorial Hospital — Willmar, Minnesota, United States
Minnesota Oncology Hematology PA-Woodbury — Woodbury, Minnesota, United States
Fairview Lakes Medical Center — Wyoming, Minnesota, United States
University of Mississippi Medical Center — Jackson, Mississippi, United States
Mercy Oncology and Hematology - Clayton-Clarkson — Ballwin, Missouri, United States
Central Care Cancer Center - Bolivar — Bolivar, Missouri, United States
Parkland Health Center-Bonne Terre — Bonne Terre, Missouri, United States
Cox Cancer Center Branson — Branson, Missouri, United States
Mercy Cancer Center - Cape Girardeau — Cape Girardeau, Missouri, United States
Saint Francis Medical Center — Cape Girardeau, Missouri, United States
Siteman Cancer Center at Saint Peters Hospital — City of Saint Peters, Missouri, United States
Siteman Cancer Center at West County Hospital — Creve Coeur, Missouri, United States
Parkland Health Center - Farmington — Farmington, Missouri, United States
MU Health Care Goldschmidt Cancer Center — Jefferson City, Missouri, United States
Freeman Health System — Joplin, Missouri, United States
Mercy Hospital Joplin — Joplin, Missouri, United States
University Health Truman Medical Center — Kansas City, Missouri, United States
University of Kansas Cancer Center - Lee's Summit — Lee's Summit, Missouri, United States
Mercy Clinic-Rolla-Cancer and Hematology — Rolla, Missouri, United States
Phelps Health Delbert Day Cancer Institute — Rolla, Missouri, United States
Heartland Regional Medical Center — Saint Joseph, Missouri, United States
Sainte Genevieve County Memorial Hospital — Sainte Genevieve, Missouri, United States
Mercy Hospital Springfield — Springfield, Missouri, United States
CoxHealth South Hospital — Springfield, Missouri, United States
Mercy Infusion Center - Chippewa — St Louis, Missouri, United States
Washington University School of Medicine — St Louis, Missouri, United States
Mercy Hospital South — St Louis, Missouri, United States
Siteman Cancer Center-South County — St Louis, Missouri, United States
Missouri Baptist Medical Center — St Louis, Missouri, United States
Siteman Cancer Center at Christian Hospital — St Louis, Missouri, United States
Mercy Hospital Saint Louis — St Louis, Missouri, United States
Missouri Baptist Sullivan Hospital — Sullivan, Missouri, United States
Mercy Hospital Washington — Washington, Missouri, United States
Community Hospital of Anaconda — Anaconda, Montana, United States
Billings Clinic Cancer Center — Billings, Montana, United States
Bozeman Health Deaconess Hospital — Bozeman, Montana, United States
Benefis Sletten Cancer Institute — Great Falls, Montana, United States
Great Falls Clinic — Great Falls, Montana, United States
Saint Peter's Community Hospital — Helena, Montana, United States
Logan Health Medical Center — Kalispell, Montana, United States
Saint Patrick Hospital - Community Hospital — Missoula, Montana, United States
Community Medical Center — Missoula, Montana, United States
Nebraska Medicine-Bellevue — Bellevue, Nebraska, United States
Nebraska Cancer Specialists/Oncology Hematology West PC — Grand Island, Nebraska, United States
CHI Health Good Samaritan — Kearney, Nebraska, United States
Saint Elizabeth Regional Medical Center — Lincoln, Nebraska, United States
Nebraska Cancer Specialists/Oncology Hematology West PC - MECC — Omaha, Nebraska, United States
Nebraska Methodist Hospital — Omaha, Nebraska, United States
Oncology Associates PC — Omaha, Nebraska, United States
Nebraska Medicine-Village Pointe — Omaha, Nebraska, United States
Alegent Health Immanuel Medical Center — Omaha, Nebraska, United States
Alegent Health Bergan Mercy Medical Center — Omaha, Nebraska, United States
Alegent Health Lakeside Hospital — Omaha, Nebraska, United States
University of Nebraska Medical Center — Omaha, Nebraska, United States
Midlands Community Hospital — Papillion, Nebraska, United States
Carson Tahoe Regional Medical Center — Carson City, Nevada, United States
Cancer and Blood Specialists-Henderson — Henderson, Nevada, United States
Comprehensive Cancer Centers of Nevada - Henderson — Henderson, Nevada, United States
Comprehensive Cancer Centers of Nevada-Horizon Ridge — Henderson, Nevada, United States
Las Vegas Cancer Center-Henderson — Henderson, Nevada, United States
Comprehensive Cancer Centers of Nevada-Southeast Henderson — Henderson, Nevada, United States
Las Vegas Urology - Green Valley — Henderson, Nevada, United States
Las Vegas Urology - Pebble — Henderson, Nevada, United States
Oncology Las Vegas - Henderson — Henderson, Nevada, United States
Urology Specialists of Nevada - Green Valley — Henderson, Nevada, United States
Las Vegas Urology - Pecos — Las Vegas, Nevada, United States
Desert West Surgery — Las Vegas, Nevada, United States
OptumCare Cancer Care at Charleston — Las Vegas, Nevada, United States
University Medical Center of Southern Nevada — Las Vegas, Nevada, United States
Hope Cancer Care of Nevada — Las Vegas, Nevada, United States
Cancer and Blood Specialists-Shadow — Las Vegas, Nevada, United States
Radiation Oncology Centers of Nevada Central — Las Vegas, Nevada, United States
Urology Specialists of Nevada - Central — Las Vegas, Nevada, United States
HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway — Las Vegas, Nevada, United States
Sunrise Hospital and Medical Center — Las Vegas, Nevada, United States
HealthCare Partners Medical Group Oncology/Hematology-San Martin — Las Vegas, Nevada, United States
Las Vegas Prostate Cancer Center — Las Vegas, Nevada, United States
Las Vegas Urology - Sunset — Las Vegas, Nevada, United States
Urology Specialists of Nevada - Southwest — Las Vegas, Nevada, United States
Radiation Oncology Centers of Nevada Southeast — Las Vegas, Nevada, United States
Ann M Wierman MD LTD — Las Vegas, Nevada, United States
Cancer and Blood Specialists-Tenaya — Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada - Northwest — Las Vegas, Nevada, United States
HealthCare Partners Medical Group Oncology/Hematology-Tenaya — Las Vegas, Nevada, United States
Las Vegas Urology - Cathedral Rock — Las Vegas, Nevada, United States
Las Vegas Urology - Smoke Ranch — Las Vegas, Nevada, United States
Oncology Las Vegas - Tenaya — Las Vegas, Nevada, United States
OptumCare Cancer Care at MountainView — Las Vegas, Nevada, United States
Urology Specialists of Nevada - Northwest — Las Vegas, Nevada, United States
Alliance for Childhood Diseases/Cure 4 the Kids Foundation — Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada - Town Center — Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada-Summerlin — Las Vegas, Nevada, United States
Summerlin Hospital Medical Center — Las Vegas, Nevada, United States
Las Vegas Cancer Center-Medical Center — Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada — Las Vegas, Nevada, United States
HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills — Las Vegas, Nevada, United States
Comprehensive Cancer Centers of Nevada - Central Valley — Las Vegas, Nevada, United States
University Cancer Center — Las Vegas, Nevada, United States
OptumCare Cancer Care at Fort Apache — Las Vegas, Nevada, United States
Hope Cancer Care of Nevada-Pahrump — Pahrump, Nevada, United States
Renown Regional Medical Center — Reno, Nevada, United States
Saint Mary's Regional Medical Center — Reno, Nevada, United States
Radiation Oncology Associates — Reno, Nevada, United States
Memorial Sloan Kettering Basking Ridge — Basking Ridge, New Jersey, United States
Memorial Sloan Kettering Monmouth — Middletown, New Jersey, United States
Memorial Sloan Kettering Bergen — Montvale, New Jersey, United States
New York-Presbyterian/Brooklyn Methodist Hospital — Brooklyn, New York, United States
Maimonides Medical Center — Brooklyn, New York, United States
Roswell Park Cancer Institute — Buffalo, New York, United States
Memorial Sloan Kettering Commack — Commack, New York, United States
Memorial Sloan Kettering Westchester — Harrison, New York, United States
Northwell Health/Center for Advanced Medicine — Lake Success, New York, United States
NYU Langone Hospital - Long Island — Mineola, New York, United States
Laura and Isaac Perlmutter Cancer Center at NYU Langone — New York, New York, United States
NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center — New York, New York, United States
Memorial Sloan Kettering Cancer Center — New York, New York, United States
NYP/Weill Cornell Medical Center — New York, New York, United States
University of Rochester — Rochester, New York, United States
State University of New York Upstate Medical University — Syracuse, New York, United States
Memorial Sloan Kettering Nassau — Uniondale, New York, United States
UNC Lineberger Comprehensive Cancer Center — Chapel Hill, North Carolina, United States
Margaret R Pardee Memorial Hospital — Hendersonville, North Carolina, United States
Essentia Health Cancer Center-South University Clinic — Fargo, North Dakota, United States
Essentia Health - Jamestown Clinic — Jamestown, North Dakota, United States
Indu and Raj Soin Medical Center — Beavercreek, Ohio, United States
Strecker Cancer Center-Belpre — Belpre, Ohio, United States
Saint Elizabeth Boardman Hospital — Boardman, Ohio, United States
Dayton Physicians LLC-Miami Valley South — Centerville, Ohio, United States
Miami Valley Hospital South — Centerville, Ohio, United States
Adena Regional Medical Center — Chillicothe, Ohio, United States
University of Cincinnati Cancer Center-UC Medical Center — Cincinnati, Ohio, United States
Good Samaritan Hospital - Cincinnati — Cincinnati, Ohio, United States
Oncology Hematology Care Inc-Kenwood — Cincinnati, Ohio, United States
Bethesda North Hospital — Cincinnati, Ohio, United States
TriHealth Cancer Institute-Westside — Cincinnati, Ohio, United States
TriHealth Cancer Institute-Anderson — Cincinnati, Ohio, United States
Ohio State University Comprehensive Cancer Center — Columbus, Ohio, United States
Mount Carmel East Hospital — Columbus, Ohio, United States
Columbus Oncology and Hematology Associates Inc — Columbus, Ohio, United States
Riverside Methodist Hospital — Columbus, Ohio, United States
Grant Medical Center — Columbus, Ohio, United States
The Mark H Zangmeister Center — Columbus, Ohio, United States
Mount Carmel Health Center West — Columbus, Ohio, United States
Doctors Hospital — Columbus, Ohio, United States
Good Samaritan Hospital - Dayton — Dayton, Ohio, United States
Miami Valley Hospital — Dayton, Ohio, United States
Dayton Physician LLC - Englewood — Dayton, Ohio, United States
Miami Valley Hospital North — Dayton, Ohio, United States
Delaware Health Center-Grady Cancer Center — Delaware, Ohio, United States
Grady Memorial Hospital — Delaware, Ohio, United States
Dublin Methodist Hospital — Dublin, Ohio, United States
Armes Family Cancer Center — Findlay, Ohio, United States
Blanchard Valley Hospital — Findlay, Ohio, United States
Orion Cancer Care — Findlay, Ohio, United States
Atrium Medical Center-Middletown Regional Hospital — Franklin, Ohio, United States
Dayton Physicians LLC-Atrium — Franklin, Ohio, United States
Central Ohio Breast and Endocrine Surgery — Gahanna, Ohio, United States
Dayton Physicians LLC-Wayne — Greenville, Ohio, United States
Wayne Hospital — Greenville, Ohio, United States
Mount Carmel Grove City Hospital — Grove City, Ohio, United States
Greater Dayton Cancer Center — Kettering, Ohio, United States
First Dayton Cancer Care — Kettering, Ohio, United States
Kettering Medical Center — Kettering, Ohio, United States
Fairfield Medical Center — Lancaster, Ohio, United States
Saint Rita's Medical Center — Lima, Ohio, United States
OhioHealth Mansfield Hospital — Mansfield, Ohio, United States
Marietta Memorial Hospital — Marietta, Ohio, United States
OhioHealth Marion General Hospital — Marion, Ohio, United States
Memorial Hospital — Marysville, Ohio, United States
Knox Community Hospital — Mount Vernon, Ohio, United States
Licking Memorial Hospital — Newark, Ohio, United States
Newark Radiation Oncology — Newark, Ohio, United States
Mercy Health - Perrysburg Hospital — Perrysburg, Ohio, United States
Southern Ohio Medical Center — Portsmouth, Ohio, United States
Springfield Regional Cancer Center — Springfield, Ohio, United States
Springfield Regional Medical Center — Springfield, Ohio, United States
Mercy Health - Saint Vincent Hospital — Toledo, Ohio, United States
Mercy Health - Saint Anne Hospital — Toledo, Ohio, United States
Dayton Physicians LLC - Troy — Troy, Ohio, United States
Upper Valley Medical Center — Troy, Ohio, United States
Saint Joseph Warren Hospital — Warren, Ohio, United States
University of Cincinnati Cancer Center-West Chester — West Chester, Ohio, United States
Saint Ann's Hospital — Westerville, Ohio, United States
OhioHealth Westerville Medical Campus/Westerville Cancer Center — Westerville, Ohio, United States
Saint Elizabeth Youngstown Hospital — Youngstown, Ohio, United States
Genesis Healthcare System Cancer Care Center — Zanesville, Ohio, United States
Cancer Centers of Southwest Oklahoma Research — Lawton, Oklahoma, United States
University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma, United States
Mercy Hospital Oklahoma City — Oklahoma City, Oklahoma, United States
Oklahoma Cancer Specialists and Research Institute-Tulsa — Tulsa, Oklahoma, United States
Saint Alphonsus Cancer Care Center-Baker City — Baker City, Oregon, United States
Saint Charles Health System — Bend, Oregon, United States
Clackamas Radiation Oncology Center — Clackamas, Oregon, United States
Providence Cancer Institute Clackamas Clinic — Clackamas, Oregon, United States
Bay Area Hospital — Coos Bay, Oregon, United States
Providence Newberg Medical Center — Newberg, Oregon, United States
Saint Alphonsus Cancer Care Center-Ontario — Ontario, Oregon, United States
Providence Willamette Falls Medical Center — Oregon City, Oregon, United States
Providence Portland Medical Center — Portland, Oregon, United States
Providence Saint Vincent Medical Center — Portland, Oregon, United States
Oregon Health and Science University — Portland, Oregon, United States
Saint Charles Health System-Redmond — Redmond, Oregon, United States
Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania, United States
Lehigh Valley Hospital - Muhlenberg — Bethlehem, Pennsylvania, United States
Pocono Medical Center — East Stroudsburg, Pennsylvania, United States
UPMC Hillman Cancer Center Erie — Erie, Pennsylvania, United States
Saint Vincent Hospital — Erie, Pennsylvania, United States
UPMC Cancer Centers - Arnold Palmer Pavilion — Greensburg, Pennsylvania, United States
Lehigh Valley Hospital-Hazleton — Hazleton, Pennsylvania, United States
Jefferson Hospital — Jefferson Hills, Pennsylvania, United States
Forbes Hospital — Monroeville, Pennsylvania, United States
UPMC Cancer Center - Monroeville — Monroeville, Pennsylvania, United States
UPMC Hillman Cancer Center - Monroeville — Monroeville, Pennsylvania, United States
Arnold Palmer Cancer Center Medical Oncology Norwin — N. Huntingdon, Pennsylvania, United States
Allegheny Valley Hospital — Natrona Heights, Pennsylvania, United States
Allegheny General Hospital — Pittsburgh, Pennsylvania, United States
West Penn Hospital — Pittsburgh, Pennsylvania, United States
UPMC Hillman Cancer Center — Pittsburgh, Pennsylvania, United States
UPMC-Shadyside Hospital — Pittsburgh, Pennsylvania, United States
UPMC-Passavant Hospital — Pittsburgh, Pennsylvania, United States
UPMC-Saint Clair Hospital Cancer Center — Pittsburgh, Pennsylvania, United States
Wexford Health and Wellness Pavilion — Wexford, Pennsylvania, United States
Medical University of South Carolina — Charleston, South Carolina, United States
University Cancer Specialists - Alcoa — Alcoa, Tennessee, United States
Vanderbilt-Ingram Cancer Center Cool Springs — Franklin, Tennessee, United States
University of Tennessee - Knoxville — Knoxville, Tennessee, United States
Vanderbilt Breast Center at One Hundred Oaks — Nashville, Tennessee, United States
Vanderbilt University/Ingram Cancer Center — Nashville, Tennessee, United States
Saint Joseph Regional Cancer Center — Bryan, Texas, United States
UT Southwestern Simmons Cancer Center - RedBird — Dallas, Texas, United States
UT Southwestern/Simmons Cancer Center-Dallas — Dallas, Texas, United States
UT Southwestern/Simmons Cancer Center-Fort Worth — Fort Worth, Texas, United States
UT Southwestern Clinical Center at Richardson/Plano — Richardson, Texas, United States
Providence Regional Cancer System-Aberdeen — Aberdeen, Washington, United States
Overlake Medical Center — Bellevue, Washington, United States
PeaceHealth Saint Joseph Medical Center — Bellingham, Washington, United States
Highline Medical Center-Main Campus — Burien, Washington, United States
Providence Regional Cancer System-Centralia — Centralia, Washington, United States
Swedish Cancer Institute-Edmonds — Edmonds, Washington, United States
Saint Elizabeth Hospital — Enumclaw, Washington, United States
Providence Regional Cancer Partnership — Everett, Washington, United States
Saint Francis Hospital — Federal Way, Washington, United States
Swedish Cancer Institute-Issaquah — Issaquah, Washington, United States
Kadlec Clinic Hematology and Oncology — Kennewick, Washington, United States
Providence Regional Cancer System-Lacey — Lacey, Washington, United States
Saint Clare Hospital — Lakewood, Washington, United States
PeaceHealth Saint John Medical Center — Longview, Washington, United States
Harrison HealthPartners Hematology and Oncology-Poulsbo — Poulsbo, Washington, United States
Valley Medical Center — Renton, Washington, United States
Pacific Gynecology Specialists — Seattle, Washington, United States
Swedish Medical Center-Ballard Campus — Seattle, Washington, United States
Swedish Medical Center-Cherry Hill — Seattle, Washington, United States
Swedish Medical Center-First Hill — Seattle, Washington, United States
PeaceHealth United General Medical Center — Sedro-Woolley, Washington, United States
Providence Regional Cancer System-Shelton — Shelton, Washington, United States
Saint Joseph Medical Center Hematology and Oncology - Silverdale — Silverdale, Washington, United States
Franciscan Research Center-Northwest Medical Plaza — Tacoma, Washington, United States
Northwest Medical Specialties PLLC — Tacoma, Washington, United States
PeaceHealth Southwest Medical Center — Vancouver, Washington, United States
Providence Saint Mary Regional Cancer Center — Walla Walla, Washington, United States
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital — Yakima, Washington, United States
Providence Regional Cancer System-Yelm — Yelm, Washington, United States
Duluth Clinic Ashland — Ashland, Wisconsin, United States
Northwest Wisconsin Cancer Center — Ashland, Wisconsin, United States
Aurora Cancer Care-Southern Lakes VLCC — Burlington, Wisconsin, United States
Aurora Saint Luke's South Shore — Cudahy, Wisconsin, United States
Marshfield Medical Center-EC Cancer Center — Eau Claire, Wisconsin, United States
Mayo Clinic Health System-Eau Claire Clinic — Eau Claire, Wisconsin, United States
Aurora Health Care Germantown Health Center — Germantown, Wisconsin, United States
Aurora Cancer Care-Grafton — Grafton, Wisconsin, United States
Aurora BayCare Medical Center — Green Bay, Wisconsin, United States
Aurora Cancer Care-Kenosha South — Kenosha, Wisconsin, United States
Aurora Bay Area Medical Group-Marinette — Marinette, Wisconsin, United States
Marshfield Medical Center-Marshfield — Marshfield, Wisconsin, United States
Aurora Cancer Care-Milwaukee — Milwaukee, Wisconsin, United States
Aurora Saint Luke's Medical Center — Milwaukee, Wisconsin, United States
Aurora Sinai Medical Center — Milwaukee, Wisconsin, United States
Marshfield Medical Center - Minocqua — Minocqua, Wisconsin, United States
ProHealth D N Greenwald Center — Mukwonago, Wisconsin, United States
Cancer Center of Western Wisconsin — New Richmond, Wisconsin, United States
ProHealth Oconomowoc Memorial Hospital — Oconomowoc, Wisconsin, United States
Vince Lombardi Cancer Clinic - Oshkosh — Oshkosh, Wisconsin, United States
Aurora Cancer Care-Racine — Racine, Wisconsin, United States
Marshfield Medical Center-Rice Lake — Rice Lake, Wisconsin, United States
Vince Lombardi Cancer Clinic-Sheboygan — Sheboygan, Wisconsin, United States
Marshfield Medical Center-River Region at Stevens Point — Stevens Point, Wisconsin, United States
Aurora Medical Center in Summit — Summit, Wisconsin, United States
Vince Lombardi Cancer Clinic-Two Rivers — Two Rivers, Wisconsin, United States
ProHealth Waukesha Memorial Hospital — Waukesha, Wisconsin, United States
UW Cancer Center at ProHealth Care — Waukesha, Wisconsin, United States
Aurora Cancer Care-Milwaukee West — Wauwatosa, Wisconsin, United States
Aurora West Allis Medical Center — West Allis, Wisconsin, United States
Marshfield Medical Center - Weston — Weston, Wisconsin, United States
Billings Clinic-Cody — Cody, Wyoming, United States
Welch Cancer Center — Sheridan, Wyoming, United States
Pan American Center for Oncology Trials LLC — San Juan, Puerto Rico

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