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RECRUITING Phase 3 ClinicalTrials.gov

Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors

Sponsor: Children's Oncology Group • ClinicalTrials.gov ID: NCT03067181

Registry updated: 2026-08-25
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Description

This phase III trial studies how well active surveillance help doctors to monitor subjects with low risk germ cell tumors for recurrence after their tumor is removed. When the germ cell tumor has spread outside of the organ in which it developed, it is considered metastatic. Chemotherapy drugs, such as bleomycin, carboplatin, etoposide, and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. The trial studies whether carboplatin or cisplatin is the preferred chemotherapy to use in treating metastatic standard risk germ cell tumors.

Interventions

  • Best Practice (Other)
    Undergo observation
  • Biopsy Procedure (Procedure)
    Undergo a tumor biopsy
  • Biospecimen Collection (Procedure)
    Undergo blood sample collection
  • Bleomycin Sulfate (Biological)
    Given IV
  • Carboplatin (Drug)
    Given IV
  • Cisplatin (Drug)
    Given IV
  • Computed Tomography (Procedure)
    Undergo a CT scan
  • Etoposide (Drug)
    Given IV
  • Magnetic Resonance Imaging (Procedure)
    Undergo MRI
  • Pulmonary Function Test (Procedure)
    Undergo a pulmonary function test
  • Questionnaire Administration (Other)
    Ancillary studies

Eligibility criteria

Inclusion Criteria: * There is no age limit for the low risk stratum (stage I ovarian immature teratoma and stage I non-seminoma or seminoma malignant GCT \[all sites\]) * Standard risk 1: Patients must be \< 11 years of age at enrollment * Standard risk 2: Patients must be \>= 11 and \< 25 years of age at enrollment * Patients enrolling on one of the low risk arms must be newly diagnosed with a stage I germ cell tumor; for the standard risk arms, patients must be newly diagnosed with malignant germ cell tumor (stage II or higher). * Histologic confirmation of a primary extracranial germ cell tumor in any of the categories outlined below is required of all patients at enrollment , with the following exceptions: * Among patients were initially diagnosed with completely resected non-seminoma malignant GCT and later recur during observation post surgery, a diagnostic biopsy is not required for enrollment if elevated tumor markers rise to \> 5 x upper limit of normal (ULN) on at least 2 measurements taken at least 1 week apart. The pathology report of initial surgery should be provided * Patients may be enrolled without histologic or cytologic confirmation in the rare case where there are exceptionally raised tumor markers (alpha fetoprotein \[AFP- ≥ 500 ng/mL or HCG ≥ 500 IU/L) and radiologic features consistent with GCT. In addition, the treating clinician must deem that the patient's tumor is not suitable for upfront resection and that a biopsy is not in the patient's best interest; or that there is a need to start therapy urgently * Low risk immature teratoma (IT); site: ovarian; stage: any; grade: any; histology: pure immature teratoma, mixed immature and mature teratoma, (may contain microscopic foci of yolk sac tumor \[\< 3 mm\], but no other pathological evidence of MGCT); tumor markers: alpha-FP =\< 1,000 ng/mL, beta-HCG institutional normal; all ages * Low risk stage I non-seminoma MGCT; site: ovarian, testicular, or extragonadal; stage: COG stage I, FIGO stage IA and IB, American Joint Committee on Cancer (AJCC) testicular stage IA, IB and IS; histology: must contain at least one of the following: yolk sac tumor, embryonal carcinoma, or choriocarcinoma (pure or mixed); all ages * Low risk stage I seminoma-MGCT; site: testicular; stage: COG stage I; AJCC testicular stage IA IB, and IS; histology: must contain only seminoma; may contain immature/mature teratoma; may NOT contain yolk sac tumor, embryonal carcinoma, or choriocarcinoma; all ages * Standard risk 1 (SR1); site: ovarian, testicular, or extragonadal; stage: COG stage II-IV, FIGO stage IC-IV, (International Germ Cell Consensus Classification \[IGCCC\] criteria DO NOT apply); histology: must contain at least one of the following: yolk sac tumor, embryonal carcinoma, or choriocarcinoma; age (years) \< 11 * Standard risk 2 (SR2) * Site: ovarian; stage: COG stage II, III, and III-X, FIGO stage IC, II and III; histology: must contain at least one of the following: yolk sac tumor, embryonal carcinoma, or choriocarcinoma; age (years) \>= 11 and \< 25 * Site: testicular; stage: COG stage II-IV, AJCC stage II, III, IGCCC good risk; histology: must contain at least one of the following: yolk sac tumor, embryonal carcinoma, or choriocarcinoma: must be IGCCC good risk; post op: alpha-FP \< 1,000 ng/mL, beta-HCG \< 5,000 IU/mL and lactate dehydrogenase (LDH) \< 3.0 x normal; age (years) \>= 11 and \< 25 * Notes: * IGCCC criteria only apply to SR2 patients with a testicular primary tumor * Use post-op tumor marker levels to determine IGCCC risk group * Pure seminoma patients are not eligible for the standard risk arms of the study * For the low risk stage I non-seminoma MGCT and the standard risk arms, components of yolk sac tumor, embryonal carcinoma, or choriocarcinoma can be mixed with other forms of GCT, such as seminoma or mature or immature teratoma; if yolk sac tumor is the only malignant component present, then it must be deemed by the pathologist to be greater than a "microscopic component" of yolk sac tumor * Patients must have a performance status corresponding to Eastern Cooperative Oncology Group (ECOG) scores of 0, 1, 2 or 3; use Karnofsky for patients \> 16 years of age and Lansky for patients =\< 16 years of age * Organ function requirements apply ONLY to patients who will receive chemotherapy (SR1 and SR2 patients) * Adequate renal function defined as: * Creatinine clearance or radioisotope glomerular filtration rate (GFR) \>= 70 mL/min/1.73 m\^2 (within 7 days prior to enrollment) OR * A serum creatinine based on age/sex as follows (within 7 days prior to enrollment): (mg/dL) * 1 month to \< 6 months male: 0.4 female: 0.4 * 6 months to \< 1 year male: 0.5 female: 0.5 * 1 to \< 2 years male: 0.6 female: 0.6 * 2 to \< 6 years male: 0.8 female: 0.8 * 6 to \< 10 years male: 1 female: 1 * 10 to \< 13 years male: 1.2 female: 1.2 * 13 to \< 16 years: male: 1.5 female: 1.4 * \>= 16 years male: 1.7 female: 1.4 * Total bilirubin =\< 2 x upper limit of normal (ULN) for age (within 7 days prior to enrollment) * Unless due to Gilbert's disease, malignant involvement of liver or vanishing bile duct syndrome * Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) \< 3 x upper limit of normal (ULN) (within 7 days prior to enrollment) * Unless due to Gilbert's disease, malignant involvement of liver or vanishing bile duct syndrome * Peripheral absolute neutrophil count (ANC) \>= 750/mm\^3 (within 7 days prior to enrollment) AND * Platelet count \>= 75,000/mm\^3 (within 7 days prior to enrollment) * Patients enrolling on the standard risk arms must be medically fit to receive protocol treatment and with no contraindications to protocol treatment * Eligibility criteria to participate in the pilot study of the AYA-Hears instrument (patient reported outcomes \[PROs\] of ototoxicity) Note: participants in group 1 will not receive AGCT1531 protocol-directed therapy; all other AYA-HEARS patients must be enrolled on the AGCT1531 SR2 arm in order to participate * \>= 11 and \< 25 years old at enrollment * Able to fluently speak and read English * Has received prior cisplatin- or carboplatin-based chemotherapy regimen for malignancy including diagnoses other than germ cell tumor * Followed for cancer or survivorship care at one of the following institutions: * Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center * Dana Farber/Harvard Cancer Center * Hospital for Sick Children * Children's Hospital of Eastern Ontario * Oregon Health and Science University * Seattle Children's Hospital * Yale University Exclusion Criteria: * Patients with any diagnoses not listed including: * Stage I testicular cancer patients who have undergone primary RPLND (retroperitoneal lymph node dissection) * Pure ovarian or extragonadal dysgerminoma/seminoma * Pure mature teratoma * Pure immature teratoma with alpha-fetoprotein (AFP) \>= 1000 ng/mL * "Poor risk" GCT (age \>= 11 years old and COG stage IV ovarian, COG stage II- IV extragonadal, or IGCCC intermediate or poor risk testicular), or * Primary central nervous system (CNS) germ cell tumor * Germ cell tumor with somatic malignant transformation * Spermatocytic seminoma * Patients must have had no prior systemic therapy for the current cancer diagnosis * Patients must have had no prior radiation therapy with the exception of CNS irradiation of brain metastases; (this exception only applies to SR1 patients; any patients over age 11 with distant metastases to brain \[stage IV disease\] would be considered poor risk and therefore not eligible for this trial) * Patients with significant, pre-existing co-morbid respiratory disease that contraindicate the use of bleomycin are ineligible for the standard risk arms of the trial * Female patients who are pregnant since fetal toxicities and teratogenic effects have been noted for several of the study drugs; a pregnancy test is required for female patients of childbearing potential; (this criteria applies ONLY to patients who will receive chemotherapy \[SR1 and SR2 patients\]) * Lactating females who plan to breastfeed their infants; (this criteria applies ONLY to patients who will receive chemotherapy \[SR1 and SR2 patients\]) * Sexually active patients of reproductive potential who have not agreed to use an effective contraceptive method for the duration of their study participation; (this criteria applies ONLY to patients who will receive chemotherapy \[SR1 and SR2 patients\])

Conditions

Childhood Extracranial Germ Cell Tumor Extragonadal Embryonal Carcinoma Germ Cell Tumor Malignant Germ Cell Tumor Malignant Ovarian Teratoma Stage I Ovarian Choriocarcinoma Stage I Ovarian Embryonal Carcinoma AJCC v6 and v7 Stage I Ovarian Yolk Sac Tumor AJCC v6 and v7 Stage I Testicular Choriocarcinoma AJCC v6 and v7 Stage I Testicular Embryonal Carcinoma AJCC v6 and v7 Stage I Testicular Seminoma AJCC v6 and v7 Stage I Testicular Yolk Sac Tumor AJCC v6 and v7 Stage II Ovarian Choriocarcinoma Stage II Ovarian Embryonal Carcinoma AJCC v6 and v7 Stage II Ovarian Yolk Sac Tumor AJCC v6 and v7 Stage II Testicular Choriocarcinoma AJCC v6 and v7 Stage II Testicular Embryonal Carcinoma AJCC v6 and v7 Stage II Testicular Yolk Sac Tumor AJCC v6 and v7 Stage III Ovarian Choriocarcinoma Stage III Ovarian Embryonal Carcinoma AJCC v6 and v7 Stage III Ovarian Yolk Sac Tumor AJCC v6 and v7 Stage III Testicular Choriocarcinoma AJCC v6 and v7 Stage III Testicular Embryonal Carcinoma AJCC v6 and v7 Stage III Testicular Yolk Sac Tumor AJCC v6 and v7 Stage IV Ovarian Choriocarcinoma Stage IV Ovarian Embryonal Carcinoma AJCC v6 and v7 Stage IV Ovarian Yolk Sac Tumor AJCC v6 and v7 Testicular Mixed Choriocarcinoma and Embryonal Carcinoma Testicular Mixed Choriocarcinoma and Teratoma Testicular Mixed Choriocarcinoma and Yolk Sac Tumor

Locations

  • Children's Hospital of Alabama — Birmingham, Alabama, United States
  • USA Health Strada Patient Care Center — Mobile, Alabama, United States
  • Anchorage Associates in Radiation Medicine — Anchorage, Alaska, United States
  • Anchorage Radiation Therapy Center — Anchorage, Alaska, United States
  • Alaska Breast Care and Surgery LLC — Anchorage, Alaska, United States
  • Alaska Oncology and Hematology LLC — Anchorage, Alaska, United States
  • Alaska Women's Cancer Care — Anchorage, Alaska, United States
  • Anchorage Oncology Centre — Anchorage, Alaska, United States
  • Katmai Oncology Group — Anchorage, Alaska, United States
  • Providence Alaska Medical Center — Anchorage, Alaska, United States
  • Kingman Regional Medical Center — Kingman, Arizona, United States
  • Banner Children's at Desert — Mesa, Arizona, United States
  • Cancer Center at Saint Joseph's — Phoenix, Arizona, United States
  • Phoenix Childrens Hospital — Phoenix, Arizona, United States
  • Banner University Medical Center - Tucson — Tucson, Arizona, United States
  • University of Arizona Cancer Center-North Campus — Tucson, Arizona, United States
  • CHI Saint Vincent Cancer Center Hot Springs — Hot Springs, Arkansas, United States
  • Arkansas Children's Hospital — Little Rock, Arkansas, United States
  • CARTI Cancer Center — Little Rock, Arkansas, United States
  • University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States
  • Kaiser Permanente-Anaheim — Anaheim, California, United States
  • Mission Hope Medical Oncology - Arroyo Grande — Arroyo Grande, California, United States
  • PCR Oncology — Arroyo Grande, California, United States
  • Kaiser Permanente-Bellflower — Bellflower, California, United States
  • Providence Saint Joseph Medical Center/Disney Family Cancer Center — Burbank, California, United States
  • Mercy Cancer Center - Carmichael — Carmichael, California, United States
  • Mercy San Juan Medical Center — Carmichael, California, United States
  • Kaiser Permanente Downey Medical Center — Downey, California, United States
  • City of Hope Comprehensive Cancer Center — Duarte, California, United States
  • Mercy Cancer Center - Elk Grove — Elk Grove, California, United States
  • Kaiser Permanente-Fontana — Fontana, California, United States
  • UC San Diego Moores Cancer Center — La Jolla, California, United States
  • Loma Linda University Medical Center — Loma Linda, California, United States
  • Miller Children's and Women's Hospital Long Beach — Long Beach, California, United States
  • Children's Hospital Los Angeles — Los Angeles, California, United States
  • Kaiser Permanente Los Angeles Medical Center — Los Angeles, California, United States
  • Los Angeles General Medical Center — Los Angeles, California, United States
  • USC / Norris Comprehensive Cancer Center — Los Angeles, California, United States
  • Cedars-Sinai Medical Center — Los Angeles, California, United States
  • Mattel Children's Hospital UCLA — Los Angeles, California, United States
  • UCLA / Jonsson Comprehensive Cancer Center — Los Angeles, California, United States
  • Valley Children's Hospital — Madera, California, United States
  • Providence Queen of The Valley — Napa, California, United States
  • USC Norris Oncology/Hematology-Newport Beach — Newport Beach, California, United States
  • UCSF Benioff Children's Hospital Oakland — Oakland, California, United States
  • Kaiser Permanente-Oakland — Oakland, California, United States
  • Children's Hospital of Orange County — Orange, California, United States
  • Lucile Packard Children's Hospital Stanford University — Palo Alto, California, United States
  • Stanford Cancer Institute Palo Alto — Palo Alto, California, United States
  • Mercy Cancer Center - Rocklin — Rocklin, California, United States
  • Kaiser Permanente-Roseville — Roseville, California, United States
  • Mercy Cancer Center - Sacramento — Sacramento, California, United States
  • Sutter Medical Center Sacramento — Sacramento, California, United States
  • University of California Davis Comprehensive Cancer Center — Sacramento, California, United States
  • Kaiser Permanente-San Diego Mission — San Diego, California, United States
  • Rady Children's Hospital - San Diego — San Diego, California, United States
  • Naval Medical Center -San Diego — San Diego, California, United States
  • UCSF Medical Center-Mission Bay — San Francisco, California, United States
  • Pacific Central Coast Health Center-San Luis Obispo — San Luis Obispo, California, United States
  • Kaiser Permanente Medical Center - Santa Clara — Santa Clara, California, United States
  • Mission Hope Medical Oncology - Santa Maria — Santa Maria, California, United States
  • Providence Medical Foundation - Santa Rosa — Santa Rosa, California, United States
  • Providence Santa Rosa Memorial Hospital — Santa Rosa, California, United States
  • Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center — Torrance, California, United States
  • Woodland Memorial Hospital — Woodland, California, United States
  • Children's Hospital Colorado — Aurora, Colorado, United States
  • UCHealth University of Colorado Hospital — Aurora, Colorado, United States
  • Penrose-Saint Francis Healthcare — Colorado Springs, Colorado, United States
  • Rocky Mountain Cancer Centers-Penrose — Colorado Springs, Colorado, United States
  • UCHealth Memorial Hospital Central — Colorado Springs, Colorado, United States
  • Memorial Hospital North — Colorado Springs, Colorado, United States
  • Saint Francis Cancer Center — Colorado Springs, Colorado, United States
  • AdventHealth Porter — Denver, Colorado, United States
  • Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center — Denver, Colorado, United States
  • CommonSpirit Cancer Center Mercy — Durango, Colorado, United States
  • Mercy Medical Center — Durango, Colorado, United States
  • Poudre Valley Hospital — Fort Collins, Colorado, United States
  • Cancer Care and Hematology-Fort Collins — Fort Collins, Colorado, United States
  • Mountain Blue Cancer Care Center — Golden, Colorado, United States
  • UCHealth Greeley Hospital — Greeley, Colorado, United States
  • CommonSpirit Saint Anthony Hospital Cancer Center — Lakewood, Colorado, United States
  • Rocky Mountain Cancer Centers-Lakewood — Lakewood, Colorado, United States
  • AdventHealth Littleton — Littleton, Colorado, United States
  • UCHealth Lone Tree Health Center — Lone Tree, Colorado, United States
  • Longmont United Hospital — Longmont, Colorado, United States
  • Rocky Mountain Cancer Centers-Longmont — Longmont, Colorado, United States
  • Medical Center of the Rockies — Loveland, Colorado, United States
  • AdventHealth Parker — Parker, Colorado, United States
  • Rocky Mountain Cancer Centers-Parker — Parker, Colorado, United States
  • Saint Mary Corwin Medical Center — Pueblo, Colorado, United States
  • Rocky Mountain Cancer Centers - Pueblo — Pueblo, Colorado, United States
  • Rocky Mountain Cancer Centers-Thornton — Thornton, Colorado, United States
  • Connecticut Children's Medical Center — Hartford, Connecticut, United States
  • Yale University — New Haven, Connecticut, United States
  • Alfred I duPont Hospital for Children — Wilmington, Delaware, United States
  • Kaiser Permanente-Capitol Hill Medical Center — Washington D.C., District of Columbia, United States
  • MedStar Georgetown University Hospital — Washington D.C., District of Columbia, United States
  • Children's National Medical Center — Washington D.C., District of Columbia, United States
  • Broward Health Medical Center — Fort Lauderdale, Florida, United States
  • Golisano Children's Hospital of Southwest Florida — Fort Myers, Florida, United States
  • UF Health Cancer Institute - Gainesville — Gainesville, Florida, United States
  • Memorial Regional Hospital/Joe DiMaggio Children's Hospital — Hollywood, Florida, United States
  • Nemours Children's Clinic-Jacksonville — Jacksonville, Florida, United States
  • University of Miami Miller School of Medicine-Sylvester Cancer Center — Miami, Florida, United States
  • Nicklaus Children's Hospital — Miami, Florida, United States
  • Miami Cancer Institute — Miami, Florida, United States
  • AdventHealth Orlando — Orlando, Florida, United States
  • Arnold Palmer Hospital for Children — Orlando, Florida, United States
  • Nemours Children's Hospital — Orlando, Florida, United States
  • Nemours Children's Clinic - Pensacola — Pensacola, Florida, United States
  • Sacred Heart Hospital — Pensacola, Florida, United States
  • Johns Hopkins All Children's Hospital — St. Petersburg, Florida, United States
  • Tampa General Hospital — Tampa, Florida, United States
  • Saint Joseph's Hospital/Children's Hospital-Tampa — Tampa, Florida, United States
  • Saint Mary's Medical Center — West Palm Beach, Florida, United States
  • Children's Healthcare of Atlanta - Arthur M Blank Hospital — Atlanta, Georgia, United States
  • Augusta University Medical Center — Augusta, Georgia, United States
  • Atrium Health Navicent — Macon, Georgia, United States
  • Memorial Health University Medical Center — Savannah, Georgia, United States
  • Straub Clinic and Hospital — Honolulu, Hawaii, United States
  • Kaiser Permanente Moanalua Medical Center — Honolulu, Hawaii, United States
  • Kapiolani Medical Center for Women and Children — Honolulu, Hawaii, United States
  • Tripler Army Medical Center — Honolulu, Hawaii, United States
  • Saint Luke's Cancer Institute - Boise — Boise, Idaho, United States
  • Saint Luke's Cancer Institute - Fruitland — Fruitland, Idaho, United States
  • Saint Luke's Cancer Institute - Meridian — Meridian, Idaho, United States
  • Saint Luke's Cancer Institute - Nampa — Nampa, Idaho, United States
  • Saint Luke's Cancer Institute - Twin Falls — Twin Falls, Idaho, United States
  • Rush-Copley Medical Center — Aurora, Illinois, United States
  • Illinois CancerCare-Bloomington — Bloomington, Illinois, United States
  • Illinois CancerCare-Canton — Canton, Illinois, United States
  • Memorial Hospital of Carbondale — Carbondale, Illinois, United States
  • SIH Cancer Institute — Carterville, Illinois, United States
  • Illinois CancerCare-Carthage — Carthage, Illinois, United States
  • Centralia Oncology Clinic — Centralia, Illinois, United States
  • Lurie Children's Hospital-Chicago — Chicago, Illinois, United States
  • John H Stroger Jr Hospital of Cook County — Chicago, Illinois, United States
  • Rush MD Anderson Cancer Center — Chicago, Illinois, United States
  • University of Illinois — Chicago, Illinois, United States
  • University of Chicago Comprehensive Cancer Center — Chicago, Illinois, United States
  • Carle at The Riverfront — Danville, Illinois, United States
  • Cancer Care Specialists of Illinois - Decatur — Decatur, Illinois, United States
  • Decatur Memorial Hospital — Decatur, Illinois, United States
  • Illinois CancerCare-Dixon — Dixon, Illinois, United States
  • Carle Physician Group-Effingham — Effingham, Illinois, United States
  • Crossroads Cancer Center — Effingham, Illinois, United States
  • Illinois CancerCare-Eureka — Eureka, Illinois, United States
  • NorthShore University HealthSystem-Evanston Hospital — Evanston, Illinois, United States
  • Illinois CancerCare-Galesburg — Galesburg, Illinois, United States
  • Western Illinois Cancer Treatment Center — Galesburg, Illinois, United States
  • NorthShore University HealthSystem-Glenbrook Hospital — Glenview, Illinois, United States
  • NorthShore University HealthSystem-Highland Park Hospital — Highland Park, Illinois, United States
  • Illinois CancerCare-Kewanee Clinic — Kewanee, Illinois, United States
  • Illinois CancerCare-Macomb — Macomb, Illinois, United States
  • Carle Physician Group-Mattoon/Charleston — Mattoon, Illinois, United States
  • Loyola University Medical Center — Maywood, Illinois, United States
  • Cancer Care Center of O'Fallon — O'Fallon, Illinois, United States
  • HSHS Saint Elizabeth's Hospital — O'Fallon, Illinois, United States
  • Advocate Children's Hospital-Oak Lawn — Oak Lawn, Illinois, United States
  • Illinois CancerCare-Ottawa Clinic — Ottawa, Illinois, United States
  • Advocate Children's Hospital-Park Ridge — Park Ridge, Illinois, United States
  • Illinois CancerCare-Pekin — Pekin, Illinois, United States
  • OSF Saint Francis Radiation Oncology at Pekin — Pekin, Illinois, United States
  • Illinois CancerCare-Peoria — Peoria, Illinois, United States
  • OSF Saint Francis Radiation Oncology at Peoria Cancer Center — Peoria, Illinois, United States
  • Methodist Medical Center of Illinois — Peoria, Illinois, United States
  • OSF Children's Hospital of Illinois — Peoria, Illinois, United States
  • OSF Saint Francis Medical Center — Peoria, Illinois, United States
  • Illinois CancerCare-Peru — Peru, Illinois, United States
  • Valley Radiation Oncology — Peru, Illinois, United States
  • Illinois CancerCare-Princeton — Princeton, Illinois, United States
  • North Shore Medical Center — Skokie, Illinois, United States
  • Saint John's Hospital — Springfield, Illinois, United States
  • Southern Illinois University School of Medicine — Springfield, Illinois, United States
  • Springfield Clinic — Springfield, Illinois, United States
  • Springfield Memorial Hospital — Springfield, Illinois, United States
  • Southwest Illinois Health Services LLP — Swansea, Illinois, United States
  • Carle Cancer Center — Urbana, Illinois, United States
  • The Carle Foundation Hospital — Urbana, Illinois, United States
  • Illinois CancerCare - Washington — Washington, Illinois, United States
  • Rush-Copley Healthcare Center — Yorkville, Illinois, United States
  • IU Health North Hospital — Carmel, Indiana, United States
  • Deaconess Clinic Downtown — Evansville, Indiana, United States
  • Indiana University/Melvin and Bren Simon Cancer Center — Indianapolis, Indiana, United States
  • Riley Hospital for Children — Indianapolis, Indiana, United States
  • Ascension Saint Vincent Indianapolis Hospital — Indianapolis, Indiana, United States
  • Chancellor Center for Oncology — Newburgh, Indiana, United States
  • Memorial Hospital of South Bend — South Bend, Indiana, United States
  • UI Health Care Mission Cancer and Blood - Ankeny Clinic — Ankeny, Iowa, United States
  • Mercy Cancer Center-West Lakes — Clive, Iowa, United States
  • UI Health Care Mission Cancer and Blood - West Des Moines Clinic — Clive, Iowa, United States
  • Alegent Health Mercy Hospital — Council Bluffs, Iowa, United States
  • Greater Regional Medical Center — Creston, Iowa, United States
  • Blank Children's Hospital — Des Moines, Iowa, United States
  • Iowa Methodist Medical Center — Des Moines, Iowa, United States
  • UI Health Care Mission Cancer and Blood - Des Moines Clinic — Des Moines, Iowa, United States
  • Mercy Medical Center - Des Moines — Des Moines, Iowa, United States
  • UI Health Care Mission Cancer and Blood - Laurel Clinic — Des Moines, Iowa, United States
  • Iowa Lutheran Hospital — Des Moines, Iowa, United States
  • University of Iowa/Holden Comprehensive Cancer Center — Iowa City, Iowa, United States
  • UI Health Care Mission Cancer and Blood - Waukee Clinic — Waukee, Iowa, United States
  • Mercy Medical Center-West Lakes — West Des Moines, Iowa, United States
  • The Iowa Clinic PC — West Des Moines, Iowa, United States
  • Wesley Medical Center — Wichita, Kansas, United States
  • CommonSpirit Saint Joseph Hospital - Bardstown — Bardstown, Kentucky, United States
  • Commonwealth Cancer Center-Corbin — Corbin, Kentucky, United States
  • CommonSpirit Saint Joseph Hospital - Lexington — Lexington, Kentucky, United States
  • Saint Joseph Radiation Oncology Resource Center — Lexington, Kentucky, United States
  • CommonSpirit Saint Joseph Medical Center - East Lexington — Lexington, Kentucky, United States
  • University of Kentucky/Markey Cancer Center — Lexington, Kentucky, United States
  • CommonSpirit Saint Joseph Hospital London — London, Kentucky, United States
  • Jewish Hospital — Louisville, Kentucky, United States
  • Norton Children's Hospital — Louisville, Kentucky, United States
  • Saints Mary and Elizabeth Hospital — Louisville, Kentucky, United States
  • UofL Health Medical Center Northeast — Louisville, Kentucky, United States
  • CommonSpirit Saint Joseph Hospital Mount Sterling — Mount Sterling, Kentucky, United States
  • Jewish Hospital Medical Center South — Shepherdsville, Kentucky, United States
  • University Medical Center New Orleans — New Orleans, Louisiana, United States
  • Children's Hospital New Orleans — New Orleans, Louisiana, United States
  • Ochsner Medical Center Jefferson — New Orleans, Louisiana, United States
  • Eastern Maine Medical Center — Bangor, Maine, United States
  • Lafayette Family Cancer Center-EMMC — Brewer, Maine, United States
  • MaineHealth Maine Medical Center - Portland — Portland, Maine, United States
  • Maine Children's Cancer Program — Scarborough, Maine, United States
  • MaineHealth Maine Medical Center- Scarborough — Scarborough, Maine, United States
  • University of Maryland/Greenebaum Cancer Center — Baltimore, Maryland, United States
  • Sinai Hospital of Baltimore — Baltimore, Maryland, United States
  • Johns Hopkins University/Sidney Kimmel Cancer Center — Baltimore, Maryland, United States
  • Walter Reed National Military Medical Center — Bethesda, Maryland, United States
  • Tufts Children's Hospital — Boston, Massachusetts, United States
  • Tufts Medical Center — Boston, Massachusetts, United States
  • Massachusetts General Hospital Cancer Center — Boston, Massachusetts, United States
  • Dana-Farber Cancer Institute — Boston, Massachusetts, United States
  • Baystate Medical Center — Springfield, Massachusetts, United States
  • UMass Memorial Medical Center - University Campus — Worcester, Massachusetts, United States
  • C S Mott Children's Hospital — Ann Arbor, Michigan, United States
  • University of Michigan Rogel Cancer Center — Ann Arbor, Michigan, United States
  • Bronson Battle Creek — Battle Creek, Michigan, United States
  • Children's Hospital of Michigan — Detroit, Michigan, United States
  • Henry Ford Health Saint John Hospital — Detroit, Michigan, United States
  • Michigan State University — East Lansing, Michigan, United States
  • OSF Saint Francis Hospital and Medical Group — Escanaba, Michigan, United States
  • Hurley Medical Center — Flint, Michigan, United States
  • Corewell Health Grand Rapids Hospitals - Butterworth Hospital — Grand Rapids, Michigan, United States
  • Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital — Grand Rapids, Michigan, United States
  • Trinity Health Grand Rapids Hospital — Grand Rapids, Michigan, United States
  • Bronson Methodist Hospital — Kalamazoo, Michigan, United States
  • West Michigan Cancer Center — Kalamazoo, Michigan, United States
  • Beacon Kalamazoo — Kalamazoo, Michigan, United States
  • Trinity Health Muskegon Hospital — Muskegon, Michigan, United States
  • Corewell Health Lakeland Hospitals - Niles Hospital — Niles, Michigan, United States
  • Lake Huron Medical Center — Port Huron, Michigan, United States
  • Corewell Health Reed City Hospital — Reed City, Michigan, United States
  • Corewell Health Children's — Royal Oak, Michigan, United States
  • Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center — Saint Joseph, Michigan, United States
  • Corewell Health Lakeland Hospitals - Saint Joseph Hospital — Saint Joseph, Michigan, United States
  • Munson Medical Center — Traverse City, Michigan, United States
  • University of Michigan Health - West — Wyoming, Michigan, United States
  • Essentia Health Cancer Center — Duluth, Minnesota, United States
  • Children's Hospitals and Clinics of Minnesota - Minneapolis — Minneapolis, Minnesota, United States
  • University of Minnesota/Masonic Cancer Center — Minneapolis, Minnesota, United States
  • Mayo Clinic in Rochester — Rochester, Minnesota, United States
  • University of Mississippi Medical Center — Jackson, Mississippi, United States
  • Parkland Health Center-Bonne Terre — Bonne Terre, Missouri, United States
  • Mercy Cancer Center - Cape Girardeau — Cape Girardeau, Missouri, United States
  • Saint Francis Medical Center — Cape Girardeau, Missouri, United States
  • University of Missouri Children's Hospital — Columbia, Missouri, United States
  • Parkland Health Center - Farmington — Farmington, Missouri, United States
  • MU Health Care Goldschmidt Cancer Center — Jefferson City, Missouri, United States
  • Children's Mercy Hospitals and Clinics — Kansas City, Missouri, United States
  • Lake Regional Hospital — Osage Beach, Missouri, United States
  • Sainte Genevieve County Memorial Hospital — Sainte Genevieve, Missouri, United States
  • Washington University School of Medicine — St Louis, Missouri, United States
  • Missouri Baptist Medical Center — St Louis, Missouri, United States
  • Mercy Hospital Saint Louis — St Louis, Missouri, United States
  • Missouri Baptist Sullivan Hospital — Sullivan, Missouri, United States
  • Saint Patrick Hospital - Community Hospital — Missoula, Montana, United States
  • Nebraska Cancer Specialists/Oncology Hematology West PC — Grand Island, Nebraska, United States
  • Fred and Pamela Buffett Cancer Center - Kearney — Kearney, Nebraska, United States
  • CHI Health Good Samaritan — Kearney, Nebraska, United States
  • Saint Elizabeth Regional Medical Center — Lincoln, Nebraska, United States
  • Children's Hospital and Medical Center of Omaha — Omaha, Nebraska, United States
  • Alegent Health Immanuel Medical Center — Omaha, Nebraska, United States
  • Hematology and Oncology Consultants PC — Omaha, Nebraska, United States
  • Alegent Health Bergan Mercy Medical Center — Omaha, Nebraska, United States
  • Alegent Health Lakeside Hospital — Omaha, Nebraska, United States
  • University of Nebraska Medical Center — Omaha, Nebraska, United States
  • Midlands Community Hospital — Papillion, Nebraska, United States
  • Carson Tahoe Regional Medical Center — Carson City, Nevada, United States
  • Cancer and Blood Specialists-Henderson — Henderson, Nevada, United States
  • Comprehensive Cancer Centers of Nevada - Henderson — Henderson, Nevada, United States
  • Comprehensive Cancer Centers of Nevada-Horizon Ridge — Henderson, Nevada, United States
  • Las Vegas Cancer Center-Henderson — Henderson, Nevada, United States
  • Comprehensive Cancer Centers of Nevada-Southeast Henderson — Henderson, Nevada, United States
  • Las Vegas Urology - Green Valley — Henderson, Nevada, United States
  • Las Vegas Urology - Pebble — Henderson, Nevada, United States
  • Urology Specialists of Nevada - Green Valley — Henderson, Nevada, United States
  • Las Vegas Urology - Pecos — Las Vegas, Nevada, United States
  • Desert West Surgery — Las Vegas, Nevada, United States
  • OptumCare Cancer Care at Charleston — Las Vegas, Nevada, United States
  • University Medical Center of Southern Nevada — Las Vegas, Nevada, United States
  • Hope Cancer Care of Nevada — Las Vegas, Nevada, United States
  • Cancer and Blood Specialists-Shadow — Las Vegas, Nevada, United States
  • Radiation Oncology Centers of Nevada Central — Las Vegas, Nevada, United States
  • Urology Specialists of Nevada - Central — Las Vegas, Nevada, United States
  • Women's Cancer Center of Nevada — Las Vegas, Nevada, United States
  • Sunrise Hospital and Medical Center — Las Vegas, Nevada, United States
  • Las Vegas Urology - Sunset — Las Vegas, Nevada, United States
  • Urology Specialists of Nevada - Southwest — Las Vegas, Nevada, United States
  • Radiation Oncology Centers of Nevada Southeast — Las Vegas, Nevada, United States
  • Cancer Therapy and Integrative Medicine — Las Vegas, Nevada, United States
  • Ann M Wierman MD LTD — Las Vegas, Nevada, United States
  • Cancer and Blood Specialists-Tenaya — Las Vegas, Nevada, United States
  • Comprehensive Cancer Centers of Nevada - Northwest — Las Vegas, Nevada, United States
  • Las Vegas Urology - Cathedral Rock — Las Vegas, Nevada, United States
  • Las Vegas Urology - Smoke Ranch — Las Vegas, Nevada, United States
  • OptumCare Cancer Care at MountainView — Las Vegas, Nevada, United States
  • Urology Specialists of Nevada - Northwest — Las Vegas, Nevada, United States
  • Alliance for Childhood Diseases/Cure 4 the Kids Foundation — Las Vegas, Nevada, United States
  • Comprehensive Cancer Centers of Nevada - Town Center — Las Vegas, Nevada, United States
  • Comprehensive Cancer Centers of Nevada-Summerlin — Las Vegas, Nevada, United States
  • Summerlin Hospital Medical Center — Las Vegas, Nevada, United States
  • Las Vegas Cancer Center-Medical Center — Las Vegas, Nevada, United States
  • Comprehensive Cancer Centers of Nevada — Las Vegas, Nevada, United States
  • Comprehensive Cancer Centers of Nevada - Central Valley — Las Vegas, Nevada, United States
  • University Cancer Center — Las Vegas, Nevada, United States
  • OptumCare Cancer Care at Fort Apache — Las Vegas, Nevada, United States
  • Hope Cancer Care of Nevada-Pahrump — Pahrump, Nevada, United States
  • Renown Regional Medical Center — Reno, Nevada, United States
  • Saint Mary's Regional Medical Center — Reno, Nevada, United States
  • Radiation Oncology Associates — Reno, Nevada, United States
  • Cancer Care Specialists - Reno — Reno, Nevada, United States
  • Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center — Lebanon, New Hampshire, United States
  • Hackensack University Medical Center — Hackensack, New Jersey, United States
  • Morristown Medical Center — Morristown, New Jersey, United States
  • Jersey Shore Medical Center — Neptune City, New Jersey, United States
  • Saint Peter's University Hospital — New Brunswick, New Jersey, United States
  • Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital — New Brunswick, New Jersey, United States
  • Newark Beth Israel Medical Center — Newark, New Jersey, United States
  • Saint Joseph's Regional Medical Center — Paterson, New Jersey, United States
  • Presbyterian Hospital — Albuquerque, New Mexico, United States
  • University of New Mexico Cancer Center — Albuquerque, New Mexico, United States
  • Albany Medical Center — Albany, New York, United States
  • Maimonides Medical Center — Brooklyn, New York, United States
  • Roswell Park Cancer Institute — Buffalo, New York, United States
  • Glens Falls Hospital — Glens Falls, New York, United States
  • NYU Langone Hospital - Long Island — Mineola, New York, United States
  • The Steven and Alexandra Cohen Children's Medical Center of New York — New Hyde Park, New York, United States
  • Laura and Isaac Perlmutter Cancer Center at NYU Langone — New York, New York, United States
  • Mount Sinai Hospital — New York, New York, United States
  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center — New York, New York, United States
  • Memorial Sloan Kettering Cancer Center — New York, New York, United States
  • University of Rochester — Rochester, New York, United States
  • Stony Brook University Medical Center — Stony Brook, New York, United States
  • State University of New York Upstate Medical University — Syracuse, New York, United States
  • Montefiore Medical Center-Einstein Campus — The Bronx, New York, United States
  • Montefiore Medical Center-Weiler Hospital — The Bronx, New York, United States
  • Children's Hospital at Montefiore — The Bronx, New York, United States
  • Montefiore Medical Center - Moses Campus — The Bronx, New York, United States
  • New York Medical College — Valhalla, New York, United States
  • Westchester Medical Center — Valhalla, New York, United States
  • Mission Hospital — Asheville, North Carolina, United States
  • UNC Lineberger Comprehensive Cancer Center — Chapel Hill, North Carolina, United States
  • Carolinas Medical Center/Levine Cancer Institute — Charlotte, North Carolina, United States
  • Novant Health Presbyterian Medical Center — Charlotte, North Carolina, United States
  • Oncology Specialists of Charlotte — Charlotte, North Carolina, United States
  • Southern Oncology Specialists-Charlotte — Charlotte, North Carolina, United States
  • Southeastern Medical Oncology Center-Clinton — Clinton, North Carolina, United States
  • Duke University Medical Center — Durham, North Carolina, United States
  • Southeastern Medical Oncology Center-Goldsboro — Goldsboro, North Carolina, United States
  • Wayne Memorial Hospital — Goldsboro, North Carolina, United States
  • East Carolina University — Greenville, North Carolina, United States
  • Novant Health Cancer Institute - Huntersville — Huntersville, North Carolina, United States
  • Southern Oncology Specialists-Huntersville — Huntersville, North Carolina, United States
  • Southeastern Medical Oncology Center-Jacksonville — Jacksonville, North Carolina, United States
  • Matthews Radiation Oncology Center — Matthews, North Carolina, United States
  • Novant Health Cancer Institute - Matthews — Matthews, North Carolina, United States
  • Novant Health Cancer Institute - Mooresville — Mooresville, North Carolina, United States
  • Novant Health Cancer Institute - Rowan — Salisbury, North Carolina, United States
  • Rowan Regional Medical Center — Salisbury, North Carolina, United States
  • Wake Forest University Health Sciences — Winston-Salem, North Carolina, United States
  • Sanford Broadway Medical Center — Fargo, North Dakota, United States
  • Children's Hospital Medical Center of Akron — Akron, Ohio, United States
  • OhioHealth O'Bleness Hospital — Athens, Ohio, United States
  • Strecker Cancer Center-Belpre — Belpre, Ohio, United States
  • Adena Regional Medical Center — Chillicothe, Ohio, United States
  • Good Samaritan Hospital - Cincinnati — Cincinnati, Ohio, United States
  • Cincinnati Children's Hospital Medical Center — Cincinnati, Ohio, United States
  • Bethesda North Hospital — Cincinnati, Ohio, United States
  • TriHealth Cancer Institute-Westside — Cincinnati, Ohio, United States
  • TriHealth Cancer Institute-Anderson — Cincinnati, Ohio, United States
  • Case Western Reserve University — Cleveland, Ohio, United States
  • Rainbow Babies and Childrens Hospital — Cleveland, Ohio, United States
  • Cleveland Clinic Foundation — Cleveland, Ohio, United States
  • Nationwide Children's Hospital — Columbus, Ohio, United States
  • Ohio State University Comprehensive Cancer Center — Columbus, Ohio, United States
  • Mount Carmel East Hospital — Columbus, Ohio, United States
  • Columbus Oncology and Hematology Associates Inc — Columbus, Ohio, United States
  • Riverside Methodist Hospital — Columbus, Ohio, United States
  • Grant Medical Center — Columbus, Ohio, United States
  • The Mark H Zangmeister Center — Columbus, Ohio, United States
  • Mount Carmel Health Center West — Columbus, Ohio, United States
  • Doctors Hospital — Columbus, Ohio, United States
  • Dayton Children's Hospital — Dayton, Ohio, United States
  • Delaware Health Center-Grady Cancer Center — Delaware, Ohio, United States
  • Grady Memorial Hospital — Delaware, Ohio, United States
  • Columbus Oncology and Hematology Associates — Dublin, Ohio, United States
  • Dublin Methodist Hospital — Dublin, Ohio, United States
  • Mount Carmel Grove City Hospital — Grove City, Ohio, United States
  • Saint Rita's Medical Center — Lima, Ohio, United States
  • OhioHealth Mansfield Hospital — Mansfield, Ohio, United States
  • Marietta Memorial Hospital — Marietta, Ohio, United States
  • OhioHealth Marion General Hospital — Marion, Ohio, United States
  • Memorial Hospital — Marysville, Ohio, United States
  • Knox Community Hospital — Mount Vernon, Ohio, United States
  • Licking Memorial Hospital — Newark, Ohio, United States
  • Mercy Health - Perrysburg Hospital — Perrysburg, Ohio, United States
  • OhioHealth Pickerington Methodist Hospital — Pickerington, Ohio, United States
  • Southern Ohio Medical Center — Portsmouth, Ohio, United States
  • ProMedica Flower Hospital — Sylvania, Ohio, United States
  • ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital — Toledo, Ohio, United States
  • Mercy Health - Saint Vincent Hospital — Toledo, Ohio, United States
  • Mercy Health - Saint Anne Hospital — Toledo, Ohio, United States
  • Saint Ann's Hospital — Westerville, Ohio, United States
  • OhioHealth Westerville Medical Campus/Westerville Cancer Center — Westerville, Ohio, United States
  • Clinton Memorial Hospital/Foster J Boyd Regional Cancer Center — Wilmington, Ohio, United States
  • Genesis Healthcare System Cancer Care Center — Zanesville, Ohio, United States
  • Cancer Centers of Southwest Oklahoma Research — Lawton, Oklahoma, United States
  • University of Oklahoma Health Sciences Center — Oklahoma City, Oklahoma, United States
  • Saint Francis Children's Hospital — Tulsa, Oklahoma, United States
  • Saint Charles Health System — Bend, Oregon, United States
  • Clackamas Radiation Oncology Center — Clackamas, Oregon, United States
  • Providence Cancer Institute Clackamas Clinic — Clackamas, Oregon, United States
  • Bay Area Hospital — Coos Bay, Oregon, United States
  • Asante Rogue Regional Medical Center — Medford, Oregon, United States
  • Providence Newberg Medical Center — Newberg, Oregon, United States
  • Providence Willamette Falls Medical Center — Oregon City, Oregon, United States
  • Providence Portland Medical Center — Portland, Oregon, United States
  • Providence Saint Vincent Medical Center — Portland, Oregon, United States
  • Legacy Emanuel Children's Hospital — Portland, Oregon, United States
  • Oregon Health and Science University — Portland, Oregon, United States
  • Jefferson Abington Hospital — Abington, Pennsylvania, United States
  • Lehigh Valley Hospital-Cedar Crest — Allentown, Pennsylvania, United States
  • Lehigh Valley Hospital - Muhlenberg — Bethlehem, Pennsylvania, United States
  • Geisinger Medical Center — Danville, Pennsylvania, United States
  • Penn State Children's Hospital — Hershey, Pennsylvania, United States
  • Children's Hospital of Philadelphia — Philadelphia, Pennsylvania, United States
  • University of Pennsylvania/Abramson Cancer Center — Philadelphia, Pennsylvania, United States
  • Saint Christopher's Hospital for Children — Philadelphia, Pennsylvania, United States
  • UPMC-Magee Womens Hospital — Pittsburgh, Pennsylvania, United States
  • Children's Hospital of Pittsburgh of UPMC — Pittsburgh, Pennsylvania, United States
  • UPMC Hillman Cancer Center — Pittsburgh, Pennsylvania, United States
  • UPMC-Passavant Hospital — Pittsburgh, Pennsylvania, United States
  • Asplundh Cancer Pavilion — Willow Grove, Pennsylvania, United States
  • Rhode Island Hospital — Providence, Rhode Island, United States
  • Prisma Health Cancer Institute - Spartanburg — Boiling Springs, South Carolina, United States
  • Medical University of South Carolina — Charleston, South Carolina, United States
  • Prisma Health Richland Hospital — Columbia, South Carolina, United States
  • Gibbs Cancer Center-Gaffney — Gaffney, South Carolina, United States
  • Saint Francis Hospital — Greenville, South Carolina, United States
  • BI-LO Charities Children's Cancer Center — Greenville, South Carolina, United States
  • Prisma Health Cancer Institute - Butternut — Greenville, South Carolina, United States
  • Prisma Health Cancer Institute - Faris — Greenville, South Carolina, United States
  • Prisma Health Greenville Memorial Hospital — Greenville, South Carolina, United States
  • Saint Francis Cancer Center — Greenville, South Carolina, United States
  • Prisma Health Cancer Institute - Eastside — Greenville, South Carolina, United States
  • Prisma Health Cancer Institute - Greer — Greer, South Carolina, United States
  • Gibbs Cancer Center-Pelham — Greer, South Carolina, United States
  • Prisma Health Cancer Institute - Seneca — Seneca, South Carolina, United States
  • North Grove Medical Park — Spartanburg, South Carolina, United States
  • Spartanburg Medical Center — Spartanburg, South Carolina, United States
  • Spartanburg Medical Center - Mary Black Campus — Spartanburg, South Carolina, United States
  • SMC Center for Hematology Oncology Union — Union, South Carolina, United States
  • Sanford USD Medical Center - Sioux Falls — Sioux Falls, South Dakota, United States
  • T C Thompson Children's Hospital — Chattanooga, Tennessee, United States
  • Memorial Hospital — Chattanooga, Tennessee, United States
  • Pulmonary Medicine Center of Chattanooga-Hixson — Hixson, Tennessee, United States
  • East Tennessee Childrens Hospital — Knoxville, Tennessee, United States
  • Saint Jude Children's Research Hospital — Memphis, Tennessee, United States
  • The Children's Hospital at TriStar Centennial — Nashville, Tennessee, United States
  • Vanderbilt University/Ingram Cancer Center — Nashville, Tennessee, United States
  • Memorial GYN Plus — Ooltewah, Tennessee, United States
  • Texas Tech University Health Sciences Center-Amarillo — Amarillo, Texas, United States
  • The Don and Sybil Harrington Cancer Center — Amarillo, Texas, United States
  • Dell Children's Medical Center of Central Texas — Austin, Texas, United States
  • Saint Joseph Regional Cancer Center — Bryan, Texas, United States
  • Driscoll Children's Hospital — Corpus Christi, Texas, United States
  • Medical City Dallas Hospital — Dallas, Texas, United States
  • Parkland Memorial Hospital — Dallas, Texas, United States
  • UT Southwestern/Simmons Cancer Center-Dallas — Dallas, Texas, United States
  • El Paso Children's Hospital — El Paso, Texas, United States
  • Texas Tech University Health Sciences Center-El Paso — El Paso, Texas, United States
  • Cook Children's Medical Center — Fort Worth, Texas, United States
  • Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center — Houston, Texas, United States
  • UT MD Anderson Cancer Center — Houston, Texas, United States
  • Covenant Children's Hospital — Lubbock, Texas, United States
  • UMC Cancer Center / UMC Health System — Lubbock, Texas, United States
  • Texas Tech University Health Sciences Center-Lubbock — Lubbock, Texas, United States
  • Children's Hospital of San Antonio — San Antonio, Texas, United States
  • Methodist Children's Hospital of South Texas — San Antonio, Texas, United States
  • University Hospital — San Antonio, Texas, United States
  • University of Texas Health Science Center at San Antonio — San Antonio, Texas, United States
  • Scott and White Memorial Hospital — Temple, Texas, United States
  • Primary Children's Hospital — Salt Lake City, Utah, United States
  • Central Vermont Medical Center/National Life Cancer Treatment — Berlin Corners, Vermont, United States
  • University of Vermont Medical Center — Burlington, Vermont, United States
  • University of Vermont and State Agricultural College — Burlington, Vermont, United States
  • University of Virginia Cancer Center — Charlottesville, Virginia, United States
  • Children's Hospital of The King's Daughters — Norfolk, Virginia, United States
  • Naval Medical Center - Portsmouth — Portsmouth, Virginia, United States
  • VCU Massey Comprehensive Cancer Center — Richmond, Virginia, United States
  • Carilion Children's — Roanoke, Virginia, United States
  • Providence Regional Cancer System-Aberdeen — Aberdeen, Washington, United States
  • Overlake Medical Center — Bellevue, Washington, United States
  • PeaceHealth Saint Joseph Medical Center — Bellingham, Washington, United States
  • Highline Medical Center-Main Campus — Burien, Washington, United States
  • Providence Regional Cancer System-Centralia — Centralia, Washington, United States
  • Swedish Cancer Institute-Edmonds — Edmonds, Washington, United States
  • Saint Elizabeth Hospital — Enumclaw, Washington, United States
  • Providence Regional Cancer Partnership — Everett, Washington, United States
  • Saint Francis Hospital — Federal Way, Washington, United States
  • Swedish Cancer Institute-Issaquah — Issaquah, Washington, United States
  • Kadlec Clinic Hematology and Oncology — Kennewick, Washington, United States
  • Providence Regional Cancer System-Lacey — Lacey, Washington, United States
  • Saint Clare Hospital — Lakewood, Washington, United States
  • PeaceHealth Saint John Medical Center — Longview, Washington, United States
  • Harrison HealthPartners Hematology and Oncology-Poulsbo — Poulsbo, Washington, United States
  • Pacific Gynecology Specialists — Seattle, Washington, United States
  • Seattle Children's Hospital — Seattle, Washington, United States
  • Swedish Medical Center-Ballard Campus — Seattle, Washington, United States
  • Kaiser Permanente Washington — Seattle, Washington, United States
  • Swedish Medical Center-Cherry Hill — Seattle, Washington, United States
  • Swedish Medical Center-First Hill — Seattle, Washington, United States
  • Providence Regional Cancer System-Shelton — Shelton, Washington, United States
  • Saint Joseph Medical Center Hematology and Oncology - Silverdale — Silverdale, Washington, United States
  • MultiCare Deaconess Cancer and Blood Specialty Center - Downtown — Spokane, Washington, United States
  • Providence Sacred Heart Medical Center and Children's Hospital — Spokane, Washington, United States
  • MultiCare Deaconess Cancer and Blood Specialty Center - North — Spokane, Washington, United States
  • MultiCare Deaconess Cancer and Blood Specialty Center - Valley — Spokane Valley, Washington, United States
  • Franciscan Research Center-Northwest Medical Plaza — Tacoma, Washington, United States
  • Mary Bridge Children's Hospital and Health Center — Tacoma, Washington, United States
  • Northwest Medical Specialties PLLC — Tacoma, Washington, United States
  • Madigan Army Medical Center — Tacoma, Washington, United States
  • PeaceHealth Southwest Medical Center — Vancouver, Washington, United States
  • Providence Saint Mary Regional Cancer Center — Walla Walla, Washington, United States
  • North Star Lodge Cancer Center at Yakima Valley Memorial Hospital — Yakima, Washington, United States
  • Providence Regional Cancer System-Yelm — Yelm, Washington, United States
  • United Hospital Center — Bridgeport, West Virginia, United States
  • West Virginia University Charleston Division — Charleston, West Virginia, United States
  • Edwards Comprehensive Cancer Center — Huntington, West Virginia, United States
  • WVUH-Berkely Medical Center — Martinsburg, West Virginia, United States
  • West Virginia University Healthcare — Morgantown, West Virginia, United States
  • Camden Clark Medical Center — Parkersburg, West Virginia, United States
  • Green Bay Oncology at Saint Vincent Hospital — Green Bay, Wisconsin, United States
  • Saint Vincent Hospital Cancer Center Green Bay — Green Bay, Wisconsin, United States
  • Saint Vincent Hospital Cancer Center at Saint Mary's — Green Bay, Wisconsin, United States
  • University of Wisconsin Carbone Cancer Center - Johnson Creek — Johnson Creek, Wisconsin, United States
  • University of Wisconsin Carbone Cancer Center - Eastpark Medical Center — Madison, Wisconsin, United States
  • University of Wisconsin Carbone Cancer Center - University Hospital — Madison, Wisconsin, United States
  • Holy Family Memorial Hospital — Manitowoc, Wisconsin, United States
  • Saint Vincent Hospital Cancer Center at Marinette — Marinette, Wisconsin, United States
  • Marshfield Medical Center-Marshfield — Marshfield, Wisconsin, United States
  • Children's Hospital of Wisconsin — Milwaukee, Wisconsin, United States
  • Saint Vincent Hospital Cancer Center at Oconto Falls — Oconto Falls, Wisconsin, United States
  • HSHS Saint Nicholas Hospital — Sheboygan, Wisconsin, United States
  • Saint Vincent Hospital Cancer Center at Sturgeon Bay — Sturgeon Bay, Wisconsin, United States
  • John Hunter Children's Hospital — Hunter Regional Mail Centre, New South Wales, Australia
  • Sydney Children's Hospital — Randwick, New South Wales, Australia
  • The Children's Hospital at Westmead — Westmead, New South Wales, Australia
  • Queensland Children's Hospital — South Brisbane, Queensland, Australia
  • Monash Medical Center-Clayton Campus — Clayton, Victoria, Australia
  • Royal Children's Hospital — Parkville, Victoria, Australia
  • Princess Margaret Hospital for Children — Perth, Western Australia, Australia
  • Perth Children's Hospital — Perth, Western Australia, Australia
  • Alberta Children's Hospital — Calgary, Alberta, Canada
  • University of Alberta Hospital — Edmonton, Alberta, Canada
  • British Columbia Children's Hospital — Vancouver, British Columbia, Canada
  • CancerCare Manitoba — Winnipeg, Manitoba, Canada
  • Janeway Child Health Centre — St. John's, Newfoundland and Labrador, Canada
  • IWK Health Centre — Halifax, Nova Scotia, Canada
  • McMaster Children's Hospital at Hamilton Health Sciences — Hamilton, Ontario, Canada
  • Kingston Health Sciences Centre — Kingston, Ontario, Canada
  • Children's Hospital — London, Ontario, Canada
  • Children's Hospital of Eastern Ontario — Ottawa, Ontario, Canada
  • Odette Cancer Centre- Sunnybrook Health Sciences Centre — Toronto, Ontario, Canada
  • Hospital for Sick Children — Toronto, Ontario, Canada
  • University Health Network-Princess Margaret Hospital — Toronto, Ontario, Canada
  • The Montreal Children's Hospital of the MUHC — Montreal, Quebec, Canada
  • Centre Hospitalier Universitaire Sainte-Justine — Montreal, Quebec, Canada
  • Centre Hospitalier Universitaire de Sherbrooke-Fleurimont — Sherbrooke, Quebec, Canada
  • CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL) — Québec, Canada
  • Tata Memorial Hospital — Mumbai, India
  • Tohoku University School of Medicine — Sendai, Aoba-ku, Japan
  • Chiba University — Chiba-sgi, Chiba, Japan
  • Niigata Cancer Centre — Niigata, Chuo-ku, Japan
  • Kyushu Univeristy — Higashiku, Fukuoka, Japan
  • Hokkaido University Hospital — Sapporo, Hokkaido, Japan
  • Hyogo Prefectural Kobe Children's Hospital — Kobe, Hyōgo, Japan
  • University of Tsukuba Hospital — Tsukuba, Ibaraki, Japan
  • Kanagawa Children's Medical Center — Yokohama, Kanagawa, Japan
  • Saitama Children's Medical Center — Chuo-ku, Saitama, Japan
  • Keio University — Shinjuku-ku, Tokyo, Japan
  • Hiroshima University Hospital — Hiroshima, Japan
  • Kyoto Perfectural University of Medicine — Kyoto, Japan
  • Hyogo College of Medicine — Nishinomiya, Hyogo, Japan
  • Osaka City General Hospital — Osaka, Japan
  • Saitama Medical University International Medical Center — Saitama, Japan
  • National Cancer Center Hospital — Tokyo, Japan
  • Kokuritsu Seiiku Medical Research Center Hospital — Tokyo, Japan
  • Starship Children's Hospital — Grafton, Auckland, New Zealand
  • Christchurch Hospital — Christchurch, New Zealand
  • HIMA San Pablo Oncologic Hospital — Caguas, Puerto Rico
  • San Jorge Children's Hospital — San Juan, Puerto Rico
  • King Faisal Specialist Hospital and Research Centre — Riyadh, Saudi Arabia
  • Sheffield Children's Hospital — Broomhall, England, United Kingdom
  • Addenbrookes Hospital-Medical School — Cambridge, England, United Kingdom
  • Saint Bartholomew's Hospital — London, England, United Kingdom
  • University College London Hospitals NHS Trust - Foley Street — London, England, United Kingdom
  • Royal Manchester Children Hospital — Manchester, England, United Kingdom
  • Royal Victoria Infirmary — Newcastle, England, United Kingdom
  • Freeman Hospital — Newcastle upon Tyne, England, United Kingdom
  • John Radcliffe Hospital — Oxford, England, United Kingdom
  • Weston Park Hospital — Sheffield, England, United Kingdom
  • Saint James's University Hospital — West Yorkshire, England, United Kingdom
  • Western General Hospital — Edinburgh, Scotland, United Kingdom
  • Royal Hospital for Children and Young People — Edinburgh, Scotland, United Kingdom
  • Beatson Oncology Center — Glasgow, Scotland, United Kingdom
  • Royal Hospital for Children — Glasgow, Scotland, United Kingdom
  • Leeds General Infirmary — West Yorkshire, United Kingdom
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Official Source

Data sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

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